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The map label for this gene is tolB

Identifier: 108563490

GI number: 108563490

Start: 1121172

End: 1122425

Strand: Reverse

Name: tolB

Synonym: HPAG1_1065

Alternate gene names: 108563490

Gene position: 1122425-1121172 (Counterclockwise)

Preceding gene: 108563491

Following gene: 108563489

Centisome position: 70.31

GC content: 37.24

Gene sequence:

>1254_bases
ATGAGATATTTATGGCTTTTTTTAATAGGCACTATAGGGCTTTTTGCAACAGATAAAACACTAGATATTATTAAAACCAT
TCAAAAACTTCCTAAGATTGAAGTGCGCTACTCTACAGATAACGATGCCAATTACGCTTTAAAATTGCATGAAGTCTTGG
CGAACGATTTAAAGACTAGCCAGCATTTTGATGTTTCTCAAAACAAGGATCAAGGCGCTATCAATTACACAGAACTCAAG
GATAAAAAAGTCCATCTTGTAGCGCTGGTGAGCGTGGCGGTAGAAAATGGCAATAAAATTTCACGATTAAAACTTTATGA
TGTCAATACAAGCACTCTTGTTAAAACTTTTGACTACCCCATTTTAAGCGCTGATCTATACCCTTTTGCAGCGCACAACA
TGGCCATTGTGGTGAATGATTATTTAAAAGCCCCTTCTATCGCTTGGATGAAGCGCCTTATTGTTTTTTCTAAATATATT
GGACCAGGAATCACAAATATCGCACTAGCCGATTATACGATGCGTTATCAAAAAGAAATCATCAAAAACAACCGACTCAA
TATTTTCCCTAAATGGGCGAACGCTGAACAAACGGAGTTTTATTACACGCAGTATGGCGAAAGAACGCCCATGATTTTAA
AATACAACATTCAAAAAGCCACTCATGAAAATATCGCTAGTTCTCAAGGAATGGCTGTGGTCTCTAGCGTGAGTTCTGAT
GGCTCTAAAATTTTAATGTCTTTAGCCCCTGATGGCCAACCGGATGTGTATTTGTATGACACGCATAAAAAAACTAAAAC
TAAAATAACGCGCTATCCTGGGATAGATGTTTCAGGAGTGTTTTTAGAAGATGACAAGTCTATGGCTTTTGTTTCGGATA
GATCCGGTTATCCTAACATCTATATGAAGAAATTGGGGTTAAAAGAGAGTGCGGAGCAACTCCTTTATGAAGGAAGAAGC
AATGAATCTATTGACGCTTATAAAGATAGTATTGTGTATGTGAGCCGAGAAAACCTTAATGAATTTGGCAAAACGGTGTT
TAATTTGAATTTGATCACTCTAAACAGCAAATATATCCGCAGGCTTACCGTGAATGGCTCTAACCAGATGCCTCGTTTTT
CTACGGATGGGAGAAATATCATGTATATCAAAAAGACACCCCAAGAATACGCCATGGGGCTTATTTTGCTAGACTATAAT
CAGAGTTTTTTATTCCCTTTAAAGAATGTGAAAATACAAGCCTTTGATTGGTAA

Upstream 100 bases:

>100_bases
TGATGACCCTTTTAAATGATTTAAAGAAAGTGGATTTTCCCCCATATCCTGGAGGAAGCATGATTTCTATTCAAGTTAAT
TTCACCACTAAGGAAGAACA

Downstream 100 bases:

>100_bases
GGTTAAATTAAGCGAATGTGAGTTAATATTGACACTTATTAAAATTTGATTCTTGGAGAATTTATAATGAAGAGATCTTC
TGTATTTAGTTCCTTGGTAG

Product: translocation protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRYLWLFLIGTIGLFATDKTLDIIKTIQKLPKIEVRYSTDNDANYALKLHEVLANDLKTSQHFDVSQNKDQGAINYTELK
DKKVHLVALVSVAVENGNKISRLKLYDVNTSTLVKTFDYPILSADLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYI
GPGITNIALADYTMRYQKEIIKNNRLNIFPKWANAEQTEFYYTQYGERTPMILKYNIQKATHENIASSQGMAVVSSVSSD
GSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNIYMKKLGLKESAEQLLYEGRS
NESIDAYKDSIVYVSRENLNEFGKTVFNLNLITLNSKYIRRLTVNGSNQMPRFSTDGRNIMYIKKTPQEYAMGLILLDYN
QSFLFPLKNVKIQAFDW

Sequences:

>Translated_417_residues
MRYLWLFLIGTIGLFATDKTLDIIKTIQKLPKIEVRYSTDNDANYALKLHEVLANDLKTSQHFDVSQNKDQGAINYTELK
DKKVHLVALVSVAVENGNKISRLKLYDVNTSTLVKTFDYPILSADLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYI
GPGITNIALADYTMRYQKEIIKNNRLNIFPKWANAEQTEFYYTQYGERTPMILKYNIQKATHENIASSQGMAVVSSVSSD
GSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNIYMKKLGLKESAEQLLYEGRS
NESIDAYKDSIVYVSRENLNEFGKTVFNLNLITLNSKYIRRLTVNGSNQMPRFSTDGRNIMYIKKTPQEYAMGLILLDYN
QSFLFPLKNVKIQAFDW
>Mature_417_residues
MRYLWLFLIGTIGLFATDKTLDIIKTIQKLPKIEVRYSTDNDANYALKLHEVLANDLKTSQHFDVSQNKDQGAINYTELK
DKKVHLVALVSVAVENGNKISRLKLYDVNTSTLVKTFDYPILSADLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYI
GPGITNIALADYTMRYQKEIIKNNRLNIFPKWANAEQTEFYYTQYGERTPMILKYNIQKATHENIASSQGMAVVSSVSSD
GSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNIYMKKLGLKESAEQLLYEGRS
NESIDAYKDSIVYVSRENLNEFGKTVFNLNLITLNSKYIRRLTVNGSNQMPRFSTDGRNIMYIKKTPQEYAMGLILLDYN
QSFLFPLKNVKIQAFDW

Specific function: Involved in the tonB-independent uptake of proteins

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLB_HELPH (Q1CSE0)

Other databases:

- EMBL:   CP000241
- RefSeq:   YP_627806.1
- ProteinModelPortal:   Q1CSE0
- STRING:   Q1CSE0
- GeneID:   4098970
- GenomeReviews:   CP000241_GR
- KEGG:   hpa:HPAG1_1065
- eggNOG:   COG0823
- HOGENOM:   HBG320885
- OMA:   LNIFPKW
- ProtClustDB:   PRK04043
- BioCyc:   HPYL357544:HPAG1_1065-MONOMER
- HAMAP:   MF_00671
- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943
- Gene3D:   G3DSA:2.130.10.10
- TIGRFAMs:   TIGR02800

Pfam domain/function: PF07676 PD40; PF04052 TolB_N

EC number: NA

Molecular weight: Translated: 47708; Mature: 47708

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLWLFLIGTIGLFATDKTLDIIKTIQKLPKIEVRYSTDNDANYALKLHEVLANDLKTS
CEEEEEEHHHHHHHEECCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCC
QHFDVSQNKDQGAINYTELKDKKVHLVALVSVAVENGNKISRLKLYDVNTSTLVKTFDYP
CCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCEEEEEEEEECCHHHEEEECCCC
ILSADLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYIGPGITNIALADYTMRYQKEI
EEECCCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHH
IKNNRLNIFPKWANAEQTEFYYTQYGERTPMILKYNIQKATHENIASSQGMAVVSSVSSD
HCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHCCCCCEEEEEECCCC
GSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNI
CCEEEEEECCCCCCCEEEEECCCCCCCEEEECCCCCEEEEEEECCCCEEEEECCCCCCCE
YMKKLGLKESAEQLLYEGRSNESIDAYKDSIVYVSRENLNEFGKTVFNLNLITLNSKYIR
EEECCCCHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCHHHHCCEEEEEEEEEECCCEEE
RLTVNGSNQMPRFSTDGRNIMYIKKTPQEYAMGLILLDYNQSFLFPLKNVKIQAFDW
EEEECCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEECCCCEEEEECCCEEEEECC
>Mature Secondary Structure
MRYLWLFLIGTIGLFATDKTLDIIKTIQKLPKIEVRYSTDNDANYALKLHEVLANDLKTS
CEEEEEEHHHHHHHEECCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCC
QHFDVSQNKDQGAINYTELKDKKVHLVALVSVAVENGNKISRLKLYDVNTSTLVKTFDYP
CCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCEEEEEEEEECCHHHEEEECCCC
ILSADLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYIGPGITNIALADYTMRYQKEI
EEECCCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHH
IKNNRLNIFPKWANAEQTEFYYTQYGERTPMILKYNIQKATHENIASSQGMAVVSSVSSD
HCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHCCCCCEEEEEECCCC
GSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNI
CCEEEEEECCCCCCCEEEEECCCCCCCEEEECCCCCEEEEEEECCCCEEEEECCCCCCCE
YMKKLGLKESAEQLLYEGRSNESIDAYKDSIVYVSRENLNEFGKTVFNLNLITLNSKYIR
EEECCCCHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCHHHHCCEEEEEEEEEECCCEEE
RLTVNGSNQMPRFSTDGRNIMYIKKTPQEYAMGLILLDYNQSFLFPLKNVKIQAFDW
EEEECCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEECCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA