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The map label for this gene is slyD [H]

Identifier: 108563487

GI number: 108563487

Start: 1119019

End: 1119576

Strand: Reverse

Name: slyD [H]

Synonym: HPAG1_1062

Alternate gene names: 108563487

Gene position: 1119576-1119019 (Counterclockwise)

Preceding gene: 108563488

Following gene: 108563486

Centisome position: 70.13

GC content: 43.73

Gene sequence:

>558_bases
ATGCAAAACCATGATTTAGAGTCAATCAAACAAGCCGCTTTGATTGAATATGAAGTGAGAGAACAAGGCTCTAGCGTTGT
GCTAGACAGCAACATTTCTAAAGAGCCTTTAGAGTTTATTATAGGTGCTAATCAAATCATAGCAGGGTTAGAAAAGGCGG
TATTAAAGGCTCAAATTGGCGAGTGGGAAGAGGTTGTCATCGCCCCAGAAGAAGCTTATGGGGTTTATGAAAGCAGCTAT
TTGCAAGAAGTCCCTAGAGATCAATTTGAAGGCATTGAATTAGAAAAAGGCATGAGCGTTTTTGGGCAAACTGAAGACAA
CCAAACCATTCAAGCCACTATCAAAGACTTTAGCAACACGCATGTGATGGTGGATTATAACCACCCATTAGCCGGGAAAA
CTTTAGCATTCCGTTTCAAGGTTTTAGGTTTTAGGGAAGTGAGCGAAGAAGAAATTTTAGCTTCACACCATGGCGGTGGG
ACAGGTTGCTGTGGCGGTCATGGGGGCCATGGCGGAAAGAAAGGTGGGGGTTGTGGTTGCTCATGTTCGCATGGATAG

Upstream 100 bases:

>100_bases
AACTATTATAAATTTTTAAACACTTTGCAACACTTGTATCCTTCAAACGAACAAGCTAAAATGGCGCAAAAAATCTTAGA
AAACAAGGAGAAACACCACC

Downstream 100 bases:

>100_bases
TAGGGTATAGGAGTCTTTAAAAGGCAAGGTCATGAATAGTTCTAACCTCAAAAATTGGCTGTTCCCTACCATTTGCTTTT
TTTTATTTTGTTATATTTTA

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MQNHDLESIKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG

Sequences:

>Translated_185_residues
MQNHDLESIKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG
>Mature_185_residues
MQNHDLESIKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDNQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
TGCCGGHGGHGGKKGGGCGCSCSHG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=139, Percent_Identity=35.9712230215827, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19985; Mature: 19985

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHDLESIKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDNQTIQATIKDFSNT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHCCCCCCCCEEEEEEHHCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGTGCCGGHGGHGGKKGGGCGC
EEEEEECCCCCCCEEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
SCSHG
CCCCC
>Mature Secondary Structure
MQNHDLESIKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDNQTIQATIKDFSNT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHCCCCCCCCEEEEEEHHCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGTGCCGGHGGHGGKKGGGCGC
EEEEEECCCCCCCEEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
SCSHG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]