| Definition | Helicobacter pylori HPAG1 chromosome, complete genome. |
|---|---|
| Accession | NC_008086 |
| Length | 1,596,366 |
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The map label for this gene is cheA [H]
Identifier: 108563425
GI number: 108563425
Start: 1054656
End: 1057064
Strand: Direct
Name: cheA [H]
Synonym: HPAG1_1000
Alternate gene names: 108563425
Gene position: 1054656-1057064 (Clockwise)
Preceding gene: 108563424
Following gene: 108563426
Centisome position: 66.07
GC content: 43.21
Gene sequence:
>2409_bases ATGGATGATTTGCAAGAAATAATGGAAGACTTCTTGATTGAAGCCTTTGAAATGAACGAGCAGTTGGATCAGGATTTAGT GGAATTGGAGCATAACCCTGAGGATTTGGACTTGCTCAATCGCATTTTTAGAGTCGCTCACACCATTAAGGGCTCTAGCT CGTTTTTGAATCTTAACATTCTCACGCACCTCACGCACAACATGGAAGATGTCTTGAATCGCGCCAGAAAGGGAGAAATC AAAATCACGCCTGATATTATGGATGTCGTGTTGCGTTCTATTGATTTGATGAAAACCTTACTCGTAACGATTAGAGATAC CGGCTCTGATACTAATAACGGCAAGGAAAACGAGATTGAAGAAGCGGTCAAACAGCTTCAAGCCATCACGAGCCAAAATT TAGAGAGCGCTAAAGAAAGGACTAAAGAAGCCCCCCAAAAAGAAAATAAAGAAGAAGCAAAAGGAGAAAATAAAGAGAAC AAGGCAAAAGCCCCTACTGCAGAAAACCCCGCAAGCGATAACCCGCTAGCCGATGAGCCGGATTTGGATTACGCTAACAT GAGCGCTGAAGAAGTGGAAGCGGAGATTGAACGGCTGCTGAATAAACGCCAAGAAGCCGATAAAGAGCGAAGAGCTCAAA AAAAACAAGAAGCCAAACAAGAAGTTGCCCCAACAAAAGAAGCCCCCAAAACAGAAACCTCCAAAGCCCCTAAAACCGAA ACGAAAGCTAAGGCTAAAGCCGATACTGAAGAAAATAAAGCCCCCTCTATTGGCGTGGAGCAAACCGTTAGGGTGGATGT GCGCCGCTTGGATCACTTAATGAATTTAATCGGTGAGCTTGTGTTAGGAAAAAATCGCTTGATTAGGATTTATAGCGATG TGGAAGAACGCTATGATGGGGAAAAGTTTTTAGAGGAATTAAACCAGGTGGTTTCTTCTATTTCAGCGGTAACGACAGAC TTGCAGCTTGCGGTGATGAAAACCAGGATGCAACCAGTGGGTAAGGTGTTCAATAAATTCCCTCGCATGGTAAGGGATTT GAGCCGGGAATTAGGCAAGAGCATTGAATTGATCATTGAGGGCGAAGAAACCGAATTAGACAAATCCATTGTAGAAGAGA TTGGCGATCCGCTCATCCACATTATCCGCAACTCATGCGATCATGGGATTGAGCCTTTAGAAGAAAGACGAAGGCTTAAC AAGCCTGAAACCGGTAAAGTGCAATTGAGCGCGTATAATGAGGGCAACCACATTGTGATTAAAATCTCTGATGATGGCAA GGGGTTAGACCCTGTGATGCTTAAAGAAAAAGCGATTGAAAAAGGGGTGATTAGCGAAAGAGACGCTGAAGGCATGAGCG ATAGGGAAGCGTTTAACCTCATTTTCAAGCCAGGTTTTTCTACCGCAAAAGTCGTTTCCAATGTTTCAGGCAGGGGTGTT GGCATGGATGTGGTGAAAACCAATATTGAAAAGCTCAATGGGATCATTGAAATTGATTCAGAAGTGGGGGTAGGCACGAC TCAAAAGCTTAAAATCCCTCTCACTCTAGCTATCATTCAAGCTTTACTCGTGGGCGTTCAAGAAGAATATTACGCTATCC CGCTTTCTTCAGTTTTAGAAACCGTGCGCATCAGCCAAGATGAAATCTACACCGTTGATGGCAAGAGCGTGTTGCGCTTG AGAGATGAGGTGCTTTCTTTGGTGCGCCTTTCTGATATTTTTAAAGTGGATGCTATTTTGGAATCCAACTCAGATGTGTA TGTGGTCATCATTGGCTTGGCTGATCAAAAAATTGGCGTGATCGTGGATTATTTAATCGGTCAAGAAGAAGTGGTCATCA AATCTTTAGGTTACTACCTTAAAAACACTAGAGGCATTGCTGGCGCTACGGTGAGAGGCGATGGGAAAATCACTCTTATT GTAGATGTGGGGGCGATGATGGATATGGCAAAAAGCATCAAGGTCAATATCACTACCTTAATGAATGAATCCGAAAACAC CAAGAGCAAAAATTCTCCTAGCGATTATATTGTCTTAGCGATTGATGATAGCAGTACGGATAGAGCGATTATCCGCAAAT GTTTAAAACCATTAGGCATCACGCTTTTAGAAGCCACTAACGGGTTAGAGGGCTTAGAAATGCTTAAAAATGGCGATAAG ATTCCGGACGCTATTTTAGTGGATATTGAGATGCCCAAGATGGACGGCTACACTTTCGCTTCTGAAGTGCGCAAATACAA TAAATTCAAAAACCTGCCTTTGATCGCAGTAACCAGTCGGGTAACTAAAACCGATAGGATGCGTGGCGTTGAATCCGGCA TGACTGAATACATCACCAAACCTTATAGCGGTGAGTATTTAACCACCGTAGTGAAGCGCAGTATTAAATTAGAAGGAGAC CAATCGTGA
Upstream 100 bases:
>100_bases AATTCACCGAAGAAATTTCTAAGATTTTAGACAAGAATGCGTAATTCTTTTTATAAAATTGTAAAATACTCTTATCTCAA ACGCTAAAAAGGGGTTTTAA
Downstream 100 bases:
>100_bases GCAACCAATTAAAAGATTTATTTGAAAGACAAAAAGAAGCTAATGCAGGTTCTAAACCAGAAGACAATGAAGAAATTTTG CAATTCATTGGCTTTATTAT
Product: autophosphorylating histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 802; Mature: 802
Protein sequence:
>802_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTKEAPQKENKEEAKGENKEN KAKAPTAENPASDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKQEVAPTKEAPKTETSKAPKTE TKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTD LQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLN KPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGV GMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLRL RDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLI VDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDK IPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEGD QS
Sequences:
>Translated_802_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTKEAPQKENKEEAKGENKEN KAKAPTAENPASDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKQEVAPTKEAPKTETSKAPKTE TKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTD LQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLN KPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGV GMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLRL RDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLI VDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDK IPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEGD QS >Mature_802_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTKEAPQKENKEEAKGENKEN KAKAPTAENPASDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKQEVAPTKEAPKTETSKAPKTE TKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTD LQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLN KPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGV GMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLRL RDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLI VDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDK IPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEGD QS
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=662, Percent_Identity=34.441087613293, Blast_Score=342, Evalue=4e-95, Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=1e-11, Organism=Escherichia coli, GI1788394, Length=87, Percent_Identity=34.4827586206897, Blast_Score=64, Evalue=5e-11, Organism=Escherichia coli, GI145693157, Length=127, Percent_Identity=29.1338582677165, Blast_Score=63, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 89497; Mature: 89497
Theoretical pI: Translated: 4.74; Mature: 4.74
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHH LTHLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLESAKERTKEAPQKENKEEAKGENKENKAKAPTAENPASDNPLADEP HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC DLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKQEVAPTKEAPKTETSKAPKTE CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH TKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDG HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCH EKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE GEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNKPETGKVQLSAYNEGNHIVI CCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEE KISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGV EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHCCCCCCC GMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLE CHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHEECCHHHHHH TVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGV HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH IVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMDMAKSIKVNITTL HHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHEEEEEEE MNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDK ECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEHHCCCHHHHHHHHCCCC IPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITK CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC PYSGEYLTTVVKRSIKLEGDQS CCCCHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHH LTHLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLESAKERTKEAPQKENKEEAKGENKENKAKAPTAENPASDNPLADEP HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC DLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKQEVAPTKEAPKTETSKAPKTE CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH TKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDG HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCH EKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE GEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNKPETGKVQLSAYNEGNHIVI CCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEE KISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRGV EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHCCCCCCC GMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLE CHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHEECCHHHHHH TVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGV HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH IVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMDMAKSIKVNITTL HHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHEEEEEEE MNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDK ECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEHHCCCHHHHHHHHCCCC IPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITK CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC PYSGEYLTTVVKRSIKLEGDQS CCCCHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]