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The map label for this gene is ispA [H]

Identifier: 108563335

GI number: 108563335

Start: 957673

End: 958584

Strand: Direct

Name: ispA [H]

Synonym: HPAG1_0910

Alternate gene names: 108563335

Gene position: 957673-958584 (Clockwise)

Preceding gene: 108563334

Following gene: 108563336

Centisome position: 59.99

GC content: 37.17

Gene sequence:

>912_bases
ATGAATAACCCTAATTTATCCTTTTATTATAATGAGTGCGAGCGTTTTGAAAGCTTTTTAAAAAACCATCATTTACACCT
TGAAAGCTTCCACCCTTATTTGGAAAAAGCCTTTTTTGAAATGGTGCTTAATGGGGGTAAAAGGTTCCGCCCTAAGCTTT
TTTTAGCCGTGCTTTGTGCGTTAGTGGGCCAAAAAGATTATTCTAACCAACAAACAGAATATTTTAAAATCGCTTTAAGC
ATTGAATGCTTGCACACTTATTCGCTCATCCATGACGATTTGCCATGCATGGATAACGCCTCTTTGAGGAGAAACCACCC
CACTTTACACGCTAAATACGATGAAACCACAGCCGTTTTAATCGGCGATGCGCTCAACACTTACTCTTTTGAATTGCTTT
CAAACGCTTTACTAGAAAGCCATATCATTGTGGAATTAATCAAAATCTTAAGCGCTAATGGGGGGATTAAAGGCATGATT
TTAGGGCAGGCTTTGGATTGCTATTTTGAGAACACGCCCTTAAATTTAGAACAACTCACTTTCTTACATGAGCATAAAAC
CGCTAAATTGATTAGCGCGAGCTTGATGATGGGGCTTGTTGCGAGCGGTATTAAAGATGAAGAGCTTTTTAAATGGCTTC
AGGCTTTTGGGTTAAAAACGGGTCTTTGTTTTCAAGTGTTAGATGATATTATAGATGTTACACAAGATGAAGAAGAAAGC
GGTAAAACCACTCATTTAGACAGCGCTAAAAACAGCTTTGTGAATTTATTAGGGCTAGAAAAGGCGAATGATTACGCTCA
AACTTTAAAGACAGAGATTTTAAACGATTTAAACCTATTAAAACCCGCTTATCCTTTATTGCAAGAAAATTTAAACGCGT
TATTGAACACTCTATTTAAAGGCAAGACATGA

Upstream 100 bases:

>100_bases
GATCATTAAAACAAGTGTGTTAAGAGGCCTCTTTAAAAAAGACCCTAAAACCAGAGCTGAATTTATGCAACTCTTAAAAT
CTTAGGTTATAATTCTGTGC

Downstream 100 bases:

>100_bases
AAAAAATATTACTCACCAACGATGATGGCTACCATGCAAAAGGCATTAAAGCTTTAGAACAGGCTTTAGAAGAAATGGCA
GAAATTTATGTGGTCGCCCC

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNNPNLSFYYNECERFESFLKNHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNALLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEEES
GKTTHLDSAKNSFVNLLGLEKANDYAQTLKTEILNDLNLLKPAYPLLQENLNALLNTLFKGKT

Sequences:

>Translated_303_residues
MNNPNLSFYYNECERFESFLKNHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNALLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEEES
GKTTHLDSAKNSFVNLLGLEKANDYAQTLKTEILNDLNLLKPAYPLLQENLNALLNTLFKGKT
>Mature_303_residues
MNNPNLSFYYNECERFESFLKNHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYSNQQTEYFKIALS
IECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNALLESHIIVELIKILSANGGIKGMI
LGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEEES
GKTTHLDSAKNSFVNLLGLEKANDYAQTLKTEILNDLNLLKPAYPLLQENLNALLNTLFKGKT

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=254, Percent_Identity=37.7952755905512, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789578, Length=252, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 34354; Mature: 34354

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPNLSFYYNECERFESFLKNHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGQKDYSNQQTEYFKIALSIECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVL
HHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEECCCCEEEE
IGDALNTYSFELLSNALLESHIIVELIKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEEES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
GKTTHLDSAKNSFVNLLGLEKANDYAQTLKTEILNDLNLLKPAYPLLQENLNALLNTLFK
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKT
CCC
>Mature Secondary Structure
MNNPNLSFYYNECERFESFLKNHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCA
CCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVGQKDYSNQQTEYFKIALSIECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVL
HHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEECCCCEEEE
IGDALNTYSFELLSNALLESHIIVELIKILSANGGIKGMILGQALDCYFENTPLNLEQLT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCHHHHH
FLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEEES
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
GKTTHLDSAKNSFVNLLGLEKANDYAQTLKTEILNDLNLLKPAYPLLQENLNALLNTLFK
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]