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The map label for this gene is yocR [H]

Identifier: 108562899

GI number: 108562899

Start: 489795

End: 491123

Strand: Direct

Name: yocR [H]

Synonym: HPAG1_0474

Alternate gene names: 108562899

Gene position: 489795-491123 (Clockwise)

Preceding gene: 108562898

Following gene: 108562900

Centisome position: 30.68

GC content: 38.0

Gene sequence:

>1329_bases
ATGGGAAAATTTTCTAAATTAGGCTTTATTTTAGCCACTTTGGGTAGCTCTATCGGTTTAGGGCATATTTGGCGCTTTCC
CTATATGGTAGGTCATAATGGGGGGAGCGCGTTTGTGCTTTTATATCTAGTGCTAACCTTGAGTTTAGGCATTGCTATGC
TTTTAGTGGAAATGCTGATTGGGAATTTGGGTAAAAAAGATGTTGTTTCTAATTATCAAATACTAGATCCTAAAAGGAAA
AAATATTACCCTTTCACTTCTTTTTTTATTTTAGGCGGCCCTCTCATTTTATCCTTTTATGCGGTGGTGTTAGGCTGGGT
GCTTTACTATCTTTTTGTAGTAACTTTTGATTTGCCTAAAGATTTAGAGCAAGCCAAAATGCAATTTAGCATGCTCCAAA
ATGGCAGTTTAACCTGGCCTGTTATTGGCTTTAGCGCATGCTTATTGCCTACAATTTGGTTTGTTTCTAGGGGGATTGAA
GAGGGGATTGAAAAATTAAATGTAGTGCTGATGCCGTTGTTGTTTGTGATTTTCATAGGGCTTTTAATTTATGCGATGAC
TTTAGAAAGCATGCCTAAAGCTTTGCGCTTTTTGTTTAATTTTGAGATTCAAAAGATTGATTTTAAGGTTGTTATGGACG
CTTTAGGGCAGATGTTCTTTTCTTTGAGTTTGGGGGTAGGCACGATTATTACTTATTCAGCTTTCACGCCCAAAAAAGAA
AACCTACTCAAAAGCTCTTTATTGATTGTCTTGCCCGGTATTTTAATCTCTTTGATTGCTGGGGTGATGATTTTCACCTT
TGTGTTTGAATACCATGCAGATGTGTCTCAAGGGCCAGGGCTTGTTTTTATTTCCTTACCTTTGACTTTCGCTAAAATGG
GCATGAGCGGGCAGATTGTCTCGCTTTTTTTCTTTATAGCGCTTGTTTTTGCTGGGATCACTTCCACGGTTTCTTTGGTA
GAGCCTTTAGCGCTTTATCTCATCAATCGTTTTAATTTCTCGCGCCTTCAAGCGTCGCTATGGATAGGGGTTGTTGTGTA
TGTTTTAGGCGTTTTAGTCATTCTTTCTATGAATGAACGATACGCTAAGTTTTTGAGTTTTGCTCATAAGAGCGTGTTTG
GATGGTTGGATTTCATCACTTCTTCATTTTTAATGCCTTTGGGAGGCTTGTTTTCAGTCTTGTTTGTAGGATGGATTTTA
AATAAAAAGCACTCTTTTTTAGCCACGAAGCATTTCTTTAACGCAAACGCTTTTAAAGCGTGGCATTTTAGCGTTCGTTT
TATCGCGCCTGTAGTGATTTTAGCGATTTTCATCTTGCAATTTAAGTGA

Upstream 100 bases:

>100_bases
GGCCCTAAATTGTTTGCAACTTGGTATTTCTTGCTTAAATATATCACCCCTTTAATTGTGTTTTCTATTTGGTTGAGCAA
GATTTATTAAAATATTTAGC

Downstream 100 bases:

>100_bases
AATAAAGATACTTGATGAAAAGCATTTTGCTCTTTATGATTTTTGTAGTTTGTCAGTTAGAAGGCAAAAAATTTTCACAA
GATAATTTTAAGGTGGATTA

Product: sodium- and chloride-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRK
KYYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLTWPVIGFSACLLPTIWFVSRGIE
EGIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALRFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
NLLKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGMSGQIVSLFFFIALVFAGITSTVSLV
EPLALYLINRFNFSRLQASLWIGVVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWIL
NKKHSFLATKHFFNANAFKAWHFSVRFIAPVVILAIFILQFK

Sequences:

>Translated_442_residues
MGKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRK
KYYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLTWPVIGFSACLLPTIWFVSRGIE
EGIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALRFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
NLLKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGMSGQIVSLFFFIALVFAGITSTVSLV
EPLALYLINRFNFSRLQASLWIGVVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWIL
NKKHSFLATKHFFNANAFKAWHFSVRFIAPVVILAIFILQFK
>Mature_441_residues
GKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLIGNLGKKDVVSNYQILDPKRKK
YYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPKDLEQAKMQFSMLQNGSLTWPVIGFSACLLPTIWFVSRGIEE
GIEKLNVVLMPLLFVIFIGLLIYAMTLESMPKALRFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKEN
LLKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGMSGQIVSLFFFIALVFAGITSTVSLVE
PLALYLINRFNFSRLQASLWIGVVVYVLGVLVILSMNERYAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWILN
KKHSFLATKHFFNANAFKAWHFSVRFIAPVVILAIFILQFK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=492, Percent_Identity=25.4065040650407, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI188528618, Length=494, Percent_Identity=23.4817813765182, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI171184408, Length=498, Percent_Identity=24.8995983935743, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184406, Length=498, Percent_Identity=24.8995983935743, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI171184404, Length=498, Percent_Identity=24.8995983935743, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4507043, Length=415, Percent_Identity=24.8192771084337, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI33354281, Length=334, Percent_Identity=26.6467065868263, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI58219014, Length=297, Percent_Identity=26.2626262626263, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657587, Length=456, Percent_Identity=23.9035087719298, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4507041, Length=379, Percent_Identity=24.802110817942, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI51468073, Length=296, Percent_Identity=24.3243243243243, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI289191351, Length=395, Percent_Identity=23.5443037974684, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4557046, Length=395, Percent_Identity=23.5443037974684, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI289191377, Length=395, Percent_Identity=23.5443037974684, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI197276623, Length=343, Percent_Identity=25.3644314868805, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI54607094, Length=343, Percent_Identity=25.3644314868805, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI92859670, Length=406, Percent_Identity=23.3990147783251, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI134304856, Length=344, Percent_Identity=24.4186046511628, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361693, Length=134, Percent_Identity=33.5820895522388, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554804, Length=362, Percent_Identity=28.4530386740331, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71998244, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI133952791, Length=277, Percent_Identity=24.5487364620939, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=121, Percent_Identity=32.2314049586777, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24661428, Length=484, Percent_Identity=25.6198347107438, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281365034, Length=489, Percent_Identity=24.9488752556237, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24652942, Length=472, Percent_Identity=24.7881355932203, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551088, Length=472, Percent_Identity=24.7881355932203, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136952, Length=366, Percent_Identity=23.7704918032787, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24762620, Length=377, Percent_Identity=27.3209549071618, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921352, Length=497, Percent_Identity=23.943661971831, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24584353, Length=497, Percent_Identity=23.943661971831, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364394, Length=365, Percent_Identity=24.3835616438356, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574704, Length=365, Percent_Identity=24.3835616438356, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136950, Length=365, Percent_Identity=24.3835616438356, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574702, Length=365, Percent_Identity=24.3835616438356, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921936, Length=403, Percent_Identity=25.8064516129032, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45551183, Length=452, Percent_Identity=25.2212389380531, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639514, Length=509, Percent_Identity=22.9862475442043, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI221329674, Length=509, Percent_Identity=22.9862475442043, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45550877, Length=505, Percent_Identity=23.960396039604, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363702, Length=475, Percent_Identity=24.2105263157895, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=27.3026315789474, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655079, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49517; Mature: 49386

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLI
CCCHHHHHHHHHHHCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GNLGKKDVVSNYQILDPKRKKYYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPK
CCCCCHHHHCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
DLEQAKMQFSMLQNGSLTWPVIGFSACLLPTIWFVSRGIEEGIEKLNVVLMPLLFVIFIG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIYAMTLESMPKALRFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCHH
NLLKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGMSGQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCHHH
SLFFFIALVFAGITSTVSLVEPLALYLINRFNFSRLQASLWIGVVVYVLGVLVILSMNER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWILNKKHSFLATKHFFNANAFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEH
WHFSVRFIAPVVILAIFILQFK
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKFSKLGFILATLGSSIGLGHIWRFPYMVGHNGGSAFVLLYLVLTLSLGIAMLLVEMLI
CCHHHHHHHHHHHCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GNLGKKDVVSNYQILDPKRKKYYPFTSFFILGGPLILSFYAVVLGWVLYYLFVVTFDLPK
CCCCCHHHHCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
DLEQAKMQFSMLQNGSLTWPVIGFSACLLPTIWFVSRGIEEGIEKLNVVLMPLLFVIFIG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIYAMTLESMPKALRFLFNFEIQKIDFKVVMDALGQMFFSLSLGVGTIITYSAFTPKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCHH
NLLKSSLLIVLPGILISLIAGVMIFTFVFEYHADVSQGPGLVFISLPLTFAKMGMSGQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCHHH
SLFFFIALVFAGITSTVSLVEPLALYLINRFNFSRLQASLWIGVVVYVLGVLVILSMNER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YAKFLSFAHKSVFGWLDFITSSFLMPLGGLFSVLFVGWILNKKHSFLATKHFFNANAFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEH
WHFSVRFIAPVVILAIFILQFK
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]