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The map label for this gene is yhdH [H]

Identifier: 108562898

GI number: 108562898

Start: 488456

End: 489784

Strand: Direct

Name: yhdH [H]

Synonym: HPAG1_0473

Alternate gene names: 108562898

Gene position: 488456-489784 (Clockwise)

Preceding gene: 108562895

Following gene: 108562899

Centisome position: 30.6

GC content: 37.55

Gene sequence:

>1329_bases
ATGGGTAATCATTTTTCTAAATTAGGATTTGTTTTAGCCGCATTAGGGAGCGCAATAGGTTTAGGGCATATTTGGCGCTT
CCCCTATATGACTGGGGTGAGCGGTGGGGGTGCTTTTGTTTTATTGTTTTTATTTTTATCTTTAAGCGTTGGCACGGCGA
TGTTTATCGCTGAAATGCTATTAGGACAAAGCACGCAAAAAAATGTAACAGAAGCTTTTAAAGATCTTGACACTAACCCT
AAAAAACGCTGGAAATACGCAGGGCTTTTGCTGATTTCTGGGCCTTTAATACTGACTTTTTATGGCACTATTTTAGGTTG
GGTGCTTTATTATTTGGTGAGTATTAGTTTTAATTTGCCTAACAGTATCCAAGAATCTGAACAAATCTTTAATGATACCT
TACAATCCATTAGGTTACAATCCATAGGGCTTTTTAGCGTTTTATTGATAACCGGATGGATCGTTTCTAGGGGGATTAAA
GAAGGCATTGAAAAACTCAATTTGGTTTTAATGCCCTTACTCTTTGCTACTTTTTTTGGTTTGCTTTTTTATGCGATGAG
CATGGATTCTTTTTCTAAAGCTTTTCATTTCATGTTTGATTTCAAACCAAAAGATTTGACCTCTCAAGTGTTCACTTATT
CCTTGGGGCAGGTTTTCTTTTCTTTAAGCATCGGTTTAGGGATCAATATCACTTACGCTGCGGTTACTGATAAAACGCAG
AATTTGCTTAAAAGCACTATTTGGGTGGTTTTATCAGGGATTTTGATTTCTCTTGTGGCAGGGCTTATGATTTTCACTTT
TGTGTTTGAATACGGGGCGAATGTCTCACAAGGCACAGGGTTAATTTTCACTTCTTTACCGGTGGTTTTTGGACAAATGG
GAGCGATAGGCGTTCTTGTTTCAATTCTTTTCTTGCTCGCGCTCGCTTTTGCTGGCATCACTTCTACGGTGGCTTTATTA
GAGCCAAGCGTGATGTATCTTACCGAAAAGTATCAATACTCTCGTTTTAAGGTTACTTGGGGTCTTGTAGCGTTGATTTT
TATCGTAGGCGTGGTGTTGATTTTCTCGCTCCATAAGGATTATAAAGATTACCTCACTTTCTTTGAAAAAAGTCTTTTTG
ATTGGTTGGATTTTGCCTCAAGCACCATTATCATGCCTTTAGGCGGAATGGCAACCTTTATTTTTATGGGCTGGGTTTTG
AAAAAAGAAAAATTGCGTCTTTTAAGCACGCACTTTTTAGGCCCTAAATTGTTTGCAACTTGGTATTTCTTGCTTAAATA
TATCACCCCTTTAATTGTGTTTTCTATTTGGTTGAGCAAGATTTATTAA

Upstream 100 bases:

>100_bases
AGATCTTTAAAGATTTTAAAAACTAATACAGCAATAGTTGGACGATTAAGGACATCGCTCTTTAATTTTAATCATTTACA
AGGAGTTTGGTAGTTAAAAT

Downstream 100 bases:

>100_bases
AATATTTAGCATGGGAAAATTTTCTAAATTAGGCTTTATTTTAGCCACTTTGGGTAGCTCTATCGGTTTAGGGCATATTT
GGCGCTTTCCCTATATGGTA

Product: sodium- and chloride-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGTAMFIAEMLLGQSTQKNVTEAFKDLDTNP
KKRWKYAGLLLISGPLILTFYGTILGWVLYYLVSISFNLPNSIQESEQIFNDTLQSIRLQSIGLFSVLLITGWIVSRGIK
EGIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINITYAAVTDKTQ
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGVLVSILFLLALAFAGITSTVALL
EPSVMYLTEKYQYSRFKVTWGLVALIFIVGVVLIFSLHKDYKDYLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVL
KKEKLRLLSTHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY

Sequences:

>Translated_442_residues
MGNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGTAMFIAEMLLGQSTQKNVTEAFKDLDTNP
KKRWKYAGLLLISGPLILTFYGTILGWVLYYLVSISFNLPNSIQESEQIFNDTLQSIRLQSIGLFSVLLITGWIVSRGIK
EGIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINITYAAVTDKTQ
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGVLVSILFLLALAFAGITSTVALL
EPSVMYLTEKYQYSRFKVTWGLVALIFIVGVVLIFSLHKDYKDYLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVL
KKEKLRLLSTHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY
>Mature_441_residues
GNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGTAMFIAEMLLGQSTQKNVTEAFKDLDTNPK
KRWKYAGLLLISGPLILTFYGTILGWVLYYLVSISFNLPNSIQESEQIFNDTLQSIRLQSIGLFSVLLITGWIVSRGIKE
GIEKLNLVLMPLLFATFFGLLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINITYAAVTDKTQN
LLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGVLVSILFLLALAFAGITSTVALLE
PSVMYLTEKYQYSRFKVTWGLVALIFIVGVVLIFSLHKDYKDYLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVLK
KEKLRLLSTHFLGPKLFATWYFLLKYITPLIVFSIWLSKIY

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI134304856, Length=352, Percent_Identity=25.8522727272727, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4507043, Length=404, Percent_Identity=25.2475247524752, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI194018524, Length=292, Percent_Identity=27.0547945205479, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI188528618, Length=373, Percent_Identity=23.8605898123324, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361581, Length=409, Percent_Identity=23.7163814180929, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI289191351, Length=385, Percent_Identity=23.3766233766234, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557046, Length=385, Percent_Identity=23.3766233766234, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI289191377, Length=386, Percent_Identity=23.3160621761658, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI58219014, Length=314, Percent_Identity=26.1146496815287, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI5032097, Length=345, Percent_Identity=24.6376811594203, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33354281, Length=329, Percent_Identity=24.9240121580547, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI171184408, Length=378, Percent_Identity=24.3386243386243, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI171184406, Length=378, Percent_Identity=24.3386243386243, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI171184404, Length=378, Percent_Identity=24.3386243386243, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI92859670, Length=111, Percent_Identity=36.9369369369369, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4507041, Length=382, Percent_Identity=22.7748691099476, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21361693, Length=118, Percent_Identity=33.0508474576271, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI11181770, Length=290, Percent_Identity=23.7931034482759, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI218563756, Length=345, Percent_Identity=24.0579710144928, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=393, Percent_Identity=25.1908396946565, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17555248, Length=116, Percent_Identity=37.0689655172414, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24661428, Length=488, Percent_Identity=25.6147540983607, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136952, Length=485, Percent_Identity=23.5051546391753, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281365034, Length=485, Percent_Identity=23.5051546391753, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19921936, Length=485, Percent_Identity=25.360824742268, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281364394, Length=485, Percent_Identity=23.5051546391753, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28574704, Length=485, Percent_Identity=23.5051546391753, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17136950, Length=485, Percent_Identity=23.5051546391753, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28574702, Length=485, Percent_Identity=23.5051546391753, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921352, Length=490, Percent_Identity=22.8571428571429, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24584353, Length=490, Percent_Identity=22.8571428571429, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652942, Length=477, Percent_Identity=23.6897274633124, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551088, Length=477, Percent_Identity=23.6897274633124, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363702, Length=470, Percent_Identity=23.8297872340426, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24639853, Length=427, Percent_Identity=23.4192037470726, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582567, Length=478, Percent_Identity=23.6401673640167, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24762620, Length=373, Percent_Identity=23.8605898123324, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363700, Length=325, Percent_Identity=26.1538461538462, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639516, Length=302, Percent_Identity=24.8344370860927, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639514, Length=302, Percent_Identity=24.8344370860927, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329674, Length=302, Percent_Identity=24.8344370860927, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550877, Length=389, Percent_Identity=25.4498714652956, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45551183, Length=459, Percent_Identity=24.6187363834423, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49395; Mature: 49264

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNHFSKLGFVLAALGSAIGLGHIWRFPYMTGVSGGGAFVLLFLFLSLSVGTAMFIAEML
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGQSTQKNVTEAFKDLDTNPKKRWKYAGLLLISGPLILTFYGTILGWVLYYLVSISFNLP
HCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
NSIQESEQIFNDTLQSIRLQSIGLFSVLLITGWIVSRGIKEGIEKLNLVLMPLLFATFFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLFYAMSMDSFSKAFHFMFDFKPKDLTSQVFTYSLGQVFFSLSIGLGINITYAAVTDKTQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHH
NLLKSTIWVVLSGILISLVAGLMIFTFVFEYGANVSQGTGLIFTSLPVVFGQMGAIGVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SILFLLALAFAGITSTVALLEPSVMYLTEKYQYSRFKVTWGLVALIFIVGVVLIFSLHKD
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKDYLTFFEKSLFDWLDFASSTIIMPLGGMATFIFMGWVLKKEKLRLLSTHFLGPKLFAT
HHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
WYFLLKYITPLIVFSIWLSKIY
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]