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The map label for this gene is fliY [H]

Identifier: 108562842

GI number: 108562842

Start: 426765

End: 427628

Strand: Direct

Name: fliY [H]

Synonym: HPAG1_0417

Alternate gene names: 108562842

Gene position: 426765-427628 (Clockwise)

Preceding gene: 108562841

Following gene: 108562843

Centisome position: 26.73

GC content: 39.12

Gene sequence:

>864_bases
ATGCAAGATTTTATTAAAATTTTTATTCAAGAGGTTGTTTCTACTTTAGAAGGGTTAGTGGGTAAGGCTTCAAGCGTGGG
ATTAGAAAAAGAAGTTTCTAATAGTGAAGAAGCTTGGGAGAGTTTGATCAGCGCGCCTTATGCAAGAGTCATGGTTAGCG
CGATTGAAAAAGAAGAGAGCTCTATTGAATTACTGGCTCCGGTAGATTTAGTTACCGCTTTAAGCGATTTGATGTTAGGA
GGTGAGGGGGCGAGTAAGGAAGAAATGGATAATGACGATTTAGACGCTTTTAAGGAAATGGCTTCTAATATTTTTGGCGC
GATCGCTACAAGCTTGAAGTCTCAAGAATTGCTCCCCAAACTCAATTTTACTACCACGAACGCTGAAATCGCTAAAGAGC
TTCCTAAAAAAGAAGATTATACTAAAGCGATGGTGTTTTCTTTTAAAATGGAAGCCATCAAAGAAAGCCAAATCATTTTA
TTGACTACGGCGGCTTTTGAGTGCCAATTTGAAAAAACGCACAAAGAAGAAAAAGAAGAAACGACACAGAGCGCTGCTGA
AGAGGTTAAAACCCATGATGCGTCTTTAGAAAACATAGAAATCCGCAATATCAGCATGCTTTTAGACGTGAAATTGAACG
TTAAGGTGCGTATCGGGCAAAAAAAGATGATTTTAAAAGATGTGGTCTCTATGGATATAGGGAGCGTGGTAGAGCTGGAT
CAATTAGTGAATGACCCTTTGGAAATTCTTGTAGATGACAAGGTGATCGCTAAGGGCGAAGTGGTGATCGTGGATGGGAA
TTTTGGCATTCAAATCACGGATATTGGCACTAAAAAAGAACGCTTAGAACAATTGAAACATTAA

Upstream 100 bases:

>100_bases
CTATAGCGAAAAAGAACGCACTAAAGAAATTTTAGAAATGCTAGAAGAACAGCGCAGAGGCAAAGTGGGCGATATTATGA
AAATAGAAGAAGAGTGAGAA

Downstream 100 bases:

>100_bases
ATCTTTTTATCATAAAAAGGAAAGGAATATGGCTATTTTTGGGGAATTAAGCTCGCTTGGGCATTTGTTTAGAAAAACAC
AAGAATTAGAAATTTTGCAT

Product: flagellar motor switch protein FliY

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MQDFIKIFIQEVVSTLEGLVGKASSVGLEKEVSNSEEAWESLISAPYARVMVSAIEKEESSIELLAPVDLVTALSDLMLG
GEGASKEEMDNDDLDAFKEMASNIFGAIATSLKSQELLPKLNFTTTNAEIAKELPKKEDYTKAMVFSFKMEAIKESQIIL
LTTAAFECQFEKTHKEEKEETTQSAAEEVKTHDASLENIEIRNISMLLDVKLNVKVRIGQKKMILKDVVSMDIGSVVELD
QLVNDPLEILVDDKVIAKGEVVIVDGNFGIQITDIGTKKERLEQLKH

Sequences:

>Translated_287_residues
MQDFIKIFIQEVVSTLEGLVGKASSVGLEKEVSNSEEAWESLISAPYARVMVSAIEKEESSIELLAPVDLVTALSDLMLG
GEGASKEEMDNDDLDAFKEMASNIFGAIATSLKSQELLPKLNFTTTNAEIAKELPKKEDYTKAMVFSFKMEAIKESQIIL
LTTAAFECQFEKTHKEEKEETTQSAAEEVKTHDASLENIEIRNISMLLDVKLNVKVRIGQKKMILKDVVSMDIGSVVELD
QLVNDPLEILVDDKVIAKGEVVIVDGNFGIQITDIGTKKERLEQLKH
>Mature_287_residues
MQDFIKIFIQEVVSTLEGLVGKASSVGLEKEVSNSEEAWESLISAPYARVMVSAIEKEESSIELLAPVDLVTALSDLMLG
GEGASKEEMDNDDLDAFKEMASNIFGAIATSLKSQELLPKLNFTTTNAEIAKELPKKEDYTKAMVFSFKMEAIKESQIIL
LTTAAFECQFEKTHKEEKEETTQSAAEEVKTHDASLENIEIRNISMLLDVKLNVKVRIGQKKMILKDVVSMDIGSVVELD
QLVNDPLEILVDDKVIAKGEVVIVDGNFGIQITDIGTKKERLEQLKH

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=125, Percent_Identity=32.8, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 31785; Mature: 31785

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFIKIFIQEVVSTLEGLVGKASSVGLEKEVSNSEEAWESLISAPYARVMVSAIEKEES
CHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCC
SIELLAPVDLVTALSDLMLGGEGASKEEMDNDDLDAFKEMASNIFGAIATSLKSQELLPK
CEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LNFTTTNAEIAKELPKKEDYTKAMVFSFKMEAIKESQIILLTTAAFECQFEKTHKEEKEE
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHEEEEHHHHHHHHHH
TTQSAAEEVKTHDASLENIEIRNISMLLDVKLNVKVRIGQKKMILKDVVSMDIGSVVELD
HHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEEECCHHHHHHHHHHHCCCHHHHHH
QLVNDPLEILVDDKVIAKGEVVIVDGNFGIQITDIGTKKERLEQLKH
HHHCCCHHEEECCCEEECCCEEEEECCCCEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MQDFIKIFIQEVVSTLEGLVGKASSVGLEKEVSNSEEAWESLISAPYARVMVSAIEKEES
CHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCCC
SIELLAPVDLVTALSDLMLGGEGASKEEMDNDDLDAFKEMASNIFGAIATSLKSQELLPK
CEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LNFTTTNAEIAKELPKKEDYTKAMVFSFKMEAIKESQIILLTTAAFECQFEKTHKEEKEE
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHEEEEHHHHHHHHHH
TTQSAAEEVKTHDASLENIEIRNISMLLDVKLNVKVRIGQKKMILKDVVSMDIGSVVELD
HHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEEECCHHHHHHHHHHHCCCHHHHHH
QLVNDPLEILVDDKVIAKGEVVIVDGNFGIQITDIGTKKERLEQLKH
HHHCCCHHEEECCCEEECCCEEEEECCCCEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]