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The map label for this gene is dppC [H]

Identifier: 108562727

GI number: 108562727

Start: 315730

End: 316587

Strand: Direct

Name: dppC [H]

Synonym: HPAG1_0302

Alternate gene names: 108562727

Gene position: 315730-316587 (Clockwise)

Preceding gene: 108562726

Following gene: 108562728

Centisome position: 19.78

GC content: 46.5

Gene sequence:

>858_bases
ATGGAGTCTTTTAGAGAGTTTATCCAACAATTCAAAAAAAATAAGGCGGCGGTGGTTGGCGCATGGATTGTGCTTTTATT
GGTAATTTGTGCTGTTTTTGCGCCCCTTTTGGCCCCGCATGACCCTTATGTCCAAAACGCGCAAGATCGCCTTTTAAAGC
CTATATGGGAGCATGGGGGGAATGCTAAATACCTTTTAGGCACTGATGATTTGGGGCGCGATATTTTGAGCCGCTTGATC
TATGGGGCTAGGATTTCTTTAACCATAGGGATTGTTTCTATGGGGATTGCGGTCTTTTTTGGCACGATACTAGGGCTAAT
AGCGGGGTATTTTGGAGGGAAAACAGATGCGGTTATCATGCGTATCATGGATATTATGTTCGCTTTGCCCTCTATTTTAT
TGATCGTGATTGTGGTTGCGGTGTTAGGGCCTTCGCTCACTAACGCCATGCTCGCTATTGGGTTTGTGGGGATTCCTGGG
TTTGCACGATTGGTGCGCAGTTCCGTGCTGGGCGAAAAAGAAAAAGAATACGTGATCGCTTCTAAAATCAATGGCTCTTC
GCATCTTCGTTTGATGTGTAAGGTGATCTTCCCTAATTGCATTATCCCTTTAATCGTGCAAACGACAATGGGTTTTGCTT
CCACGGTTTTAGAAGCGGCCGCGCTGAGCTTCTTAGGTCTTGGGGCCCAACCTCCCAAACCCGAATGGGGAGCGATGCTG
ATGAACTCCATGCAATACATCGCTACCGCTCCTTGGATGCTTGTTTTCCCTGGGGTGATGATTTTTTTAACGGTCATGAG
TTTTAATCTGGTAGGCGATGGCATCATGGACGCTTTAGATCCTAAACGCGCCTCTTAA

Upstream 100 bases:

>100_bases
TCCAGTCCATGTCTTTGATTATTGCCATGATGTATATTGGGGCTAATCTTTTGGTGGATATTTTATACGCTTTTATTGAT
CCTAGAATAAGGTTGTCATA

Downstream 100 bases:

>100_bases
AAGGAGCTTGCATGATTTTAGAAGTTAAAGATTTAAAAACTTATTTTTTCACCGATAAGGGCGTGAATAAAGCAGTAGAT
GGCGTGAGTTTTGGCTTGAA

Product: dipeptide permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MESFREFIQQFKKNKAAVVGAWIVLLLVICAVFAPLLAPHDPYVQNAQDRLLKPIWEHGGNAKYLLGTDDLGRDILSRLI
YGARISLTIGIVSMGIAVFFGTILGLIAGYFGGKTDAVIMRIMDIMFALPSILLIVIVVAVLGPSLTNAMLAIGFVGIPG
FARLVRSSVLGEKEKEYVIASKINGSSHLRLMCKVIFPNCIIPLIVQTTMGFASTVLEAAALSFLGLGAQPPKPEWGAML
MNSMQYIATAPWMLVFPGVMIFLTVMSFNLVGDGIMDALDPKRAS

Sequences:

>Translated_285_residues
MESFREFIQQFKKNKAAVVGAWIVLLLVICAVFAPLLAPHDPYVQNAQDRLLKPIWEHGGNAKYLLGTDDLGRDILSRLI
YGARISLTIGIVSMGIAVFFGTILGLIAGYFGGKTDAVIMRIMDIMFALPSILLIVIVVAVLGPSLTNAMLAIGFVGIPG
FARLVRSSVLGEKEKEYVIASKINGSSHLRLMCKVIFPNCIIPLIVQTTMGFASTVLEAAALSFLGLGAQPPKPEWGAML
MNSMQYIATAPWMLVFPGVMIFLTVMSFNLVGDGIMDALDPKRAS
>Mature_285_residues
MESFREFIQQFKKNKAAVVGAWIVLLLVICAVFAPLLAPHDPYVQNAQDRLLKPIWEHGGNAKYLLGTDDLGRDILSRLI
YGARISLTIGIVSMGIAVFFGTILGLIAGYFGGKTDAVIMRIMDIMFALPSILLIVIVVAVLGPSLTNAMLAIGFVGIPG
FARLVRSSVLGEKEKEYVIASKINGSSHLRLMCKVIFPNCIIPLIVQTTMGFASTVLEAAALSFLGLGAQPPKPEWGAML
MNSMQYIATAPWMLVFPGVMIFLTVMSFNLVGDGIMDALDPKRAS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=51.7730496453901, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=43.3691756272401, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787760, Length=277, Percent_Identity=43.6823104693141, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1787549, Length=277, Percent_Identity=39.3501805054152, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=38.5245901639344, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=34.6570397111913, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=27.6018099547511, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30836; Mature: 30836

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFREFIQQFKKNKAAVVGAWIVLLLVICAVFAPLLAPHDPYVQNAQDRLLKPIWEHGG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCC
NAKYLLGTDDLGRDILSRLIYGARISLTIGIVSMGIAVFFGTILGLIAGYFGGKTDAVIM
CEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIMDIMFALPSILLIVIVVAVLGPSLTNAMLAIGFVGIPGFARLVRSSVLGEKEKEYVIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHCEEEE
SKINGSSHLRLMCKVIFPNCIIPLIVQTTMGFASTVLEAAALSFLGLGAQPPKPEWGAML
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MNSMQYIATAPWMLVFPGVMIFLTVMSFNLVGDGIMDALDPKRAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MESFREFIQQFKKNKAAVVGAWIVLLLVICAVFAPLLAPHDPYVQNAQDRLLKPIWEHGG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHCCC
NAKYLLGTDDLGRDILSRLIYGARISLTIGIVSMGIAVFFGTILGLIAGYFGGKTDAVIM
CEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RIMDIMFALPSILLIVIVVAVLGPSLTNAMLAIGFVGIPGFARLVRSSVLGEKEKEYVIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHCEEEE
SKINGSSHLRLMCKVIFPNCIIPLIVQTTMGFASTVLEAAALSFLGLGAQPPKPEWGAML
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MNSMQYIATAPWMLVFPGVMIFLTVMSFNLVGDGIMDALDPKRAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]