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The map label for this gene is dppB [H]

Identifier: 108562726

GI number: 108562726

Start: 314726

End: 315730

Strand: Direct

Name: dppB [H]

Synonym: HPAG1_0301

Alternate gene names: 108562726

Gene position: 314726-315730 (Clockwise)

Preceding gene: 108562725

Following gene: 108562727

Centisome position: 19.72

GC content: 44.98

Gene sequence:

>1005_bases
ATGTTGAGTTTTATCATTAAGCGTATTTTGTGGGCGATCCCCACGCTGTTTGGAGTGAGCGTCATTGTGTTTATGATGGT
GCATTTAGTGCCAGGAGATCCGGCGTTAGTGATTTTAGGCGAAAAGGCCAATCAAGCCGCTATTGACGCTTTAAGGGAGC
AGTTTGGCTTGAATAAGCCTTTGATAGAGCAGTATTTTTTCTTTATCAATAACGTGTTGCATGGCAATTTTGGCGCTTCT
ATCATGACCGGTGAGCCTGTGATGCATGAATTTTTGCAACGATTCCCGGCTACGGTGGAATTGGCTTTGATCGCTCTGTT
TATGGCTCTTGTTTTGGGTATTAGTGTTGGCGTGTTAGCCGCGATCAAACGCTATAGCGTGTTTGATTATTCCAGCATGA
CTTTCGCTTTAGCCGGGATTTCTATGCCGGTGTTTTGGCTAGGGCTCATGCTGATTTATATCTTCAGCGTGCAATTGGGG
TGGTTGCCTGTTTTTGGGCGTTTGAGCGATGTGTATTATTTAGATGGCCCCACAGGTTTTTATTTGATAGACAGCTTGAT
CGCAAGGGATTATGGGGCGTTTGTGGATACCATCAAGCACTTGATTTTGCCTAGCATTGTGTTAGCCACGGTTTCTACCG
CTGTTATTGCCAGAATGACTCGCGCGAGCATGGCAGAAGTGTCTAAAGAAGATTATGTGCGCACCGCTAAAGCTAAGGGG
TGCAGCTCCTTTAGGGTGATTTTTGTGCACACTTTGCGTAACGCTTTAATCCCTGTAACGACTATCGCAGGCTTGATGTT
GGCCGGGCTTTTAGGGGGGAGCATGATAACTGAAACGGTTTTCTCATGGCCTGGGATTGGTAAGTGGATCGTTAATGCGC
TCAACCAGCGCGATTTCCCGATTATCCAGTCCATGTCTTTGATTATTGCCATGATGTATATTGGGGCTAATCTTTTGGTG
GATATTTTATACGCTTTTATTGATCCTAGAATAAGGTTGTCATAA

Upstream 100 bases:

>100_bases
TCGGTGGTGCCGCATTTGTCTAAAGTCAAAGGCTATAAGACGACCGGAGTGAGCGTGAATCGCTTCTTTAAGGTGTATTT
AGAAAAGTGAAAGGGGTTGC

Downstream 100 bases:

>100_bases
TGGAGTCTTTTAGAGAGTTTATCCAACAATTCAAAAAAAATAAGGCGGCGGTGGTTGGCGCATGGATTGTGCTTTTATTG
GTAATTTGTGCTGTTTTTGC

Product: dipeptide permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLSFIIKRILWAIPTLFGVSVIVFMMVHLVPGDPALVILGEKANQAAIDALREQFGLNKPLIEQYFFFINNVLHGNFGAS
IMTGEPVMHEFLQRFPATVELALIALFMALVLGISVGVLAAIKRYSVFDYSSMTFALAGISMPVFWLGLMLIYIFSVQLG
WLPVFGRLSDVYYLDGPTGFYLIDSLIARDYGAFVDTIKHLILPSIVLATVSTAVIARMTRASMAEVSKEDYVRTAKAKG
CSSFRVIFVHTLRNALIPVTTIAGLMLAGLLGGSMITETVFSWPGIGKWIVNALNQRDFPIIQSMSLIIAMMYIGANLLV
DILYAFIDPRIRLS

Sequences:

>Translated_334_residues
MLSFIIKRILWAIPTLFGVSVIVFMMVHLVPGDPALVILGEKANQAAIDALREQFGLNKPLIEQYFFFINNVLHGNFGAS
IMTGEPVMHEFLQRFPATVELALIALFMALVLGISVGVLAAIKRYSVFDYSSMTFALAGISMPVFWLGLMLIYIFSVQLG
WLPVFGRLSDVYYLDGPTGFYLIDSLIARDYGAFVDTIKHLILPSIVLATVSTAVIARMTRASMAEVSKEDYVRTAKAKG
CSSFRVIFVHTLRNALIPVTTIAGLMLAGLLGGSMITETVFSWPGIGKWIVNALNQRDFPIIQSMSLIIAMMYIGANLLV
DILYAFIDPRIRLS
>Mature_334_residues
MLSFIIKRILWAIPTLFGVSVIVFMMVHLVPGDPALVILGEKANQAAIDALREQFGLNKPLIEQYFFFINNVLHGNFGAS
IMTGEPVMHEFLQRFPATVELALIALFMALVLGISVGVLAAIKRYSVFDYSSMTFALAGISMPVFWLGLMLIYIFSVQLG
WLPVFGRLSDVYYLDGPTGFYLIDSLIARDYGAFVDTIKHLILPSIVLATVSTAVIARMTRASMAEVSKEDYVRTAKAKG
CSSFRVIFVHTLRNALIPVTTIAGLMLAGLLGGSMITETVFSWPGIGKWIVNALNQRDFPIIQSMSLIIAMMYIGANLLV
DILYAFIDPRIRLS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=49.1071428571429, Blast_Score=341, Evalue=3e-95,
Organism=Escherichia coli, GI1787053, Length=332, Percent_Identity=43.6746987951807, Blast_Score=283, Evalue=7e-78,
Organism=Escherichia coli, GI1787761, Length=331, Percent_Identity=42.9003021148036, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=36.1194029850746, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787497, Length=334, Percent_Identity=36.2275449101796, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=39.5604395604396, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788504, Length=374, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36891; Mature: 36891

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFIIKRILWAIPTLFGVSVIVFMMVHLVPGDPALVILGEKANQAAIDALREQFGLNKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
LIEQYFFFINNVLHGNFGASIMTGEPVMHEFLQRFPATVELALIALFMALVLGISVGVLA
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AIKRYSVFDYSSMTFALAGISMPVFWLGLMLIYIFSVQLGWLPVFGRLSDVYYLDGPTGF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHH
YLIDSLIARDYGAFVDTIKHLILPSIVLATVSTAVIARMTRASMAEVSKEDYVRTAKAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CSSFRVIFVHTLRNALIPVTTIAGLMLAGLLGGSMITETVFSWPGIGKWIVNALNQRDFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCCCCH
IIQSMSLIIAMMYIGANLLVDILYAFIDPRIRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSFIIKRILWAIPTLFGVSVIVFMMVHLVPGDPALVILGEKANQAAIDALREQFGLNKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
LIEQYFFFINNVLHGNFGASIMTGEPVMHEFLQRFPATVELALIALFMALVLGISVGVLA
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AIKRYSVFDYSSMTFALAGISMPVFWLGLMLIYIFSVQLGWLPVFGRLSDVYYLDGPTGF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHH
YLIDSLIARDYGAFVDTIKHLILPSIVLATVSTAVIARMTRASMAEVSKEDYVRTAKAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
CSSFRVIFVHTLRNALIPVTTIAGLMLAGLLGGSMITETVFSWPGIGKWIVNALNQRDFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCCCCH
IIQSMSLIIAMMYIGANLLVDILYAFIDPRIRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]