Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 108562710

GI number: 108562710

Start: 288964

End: 289995

Strand: Direct

Name: aroB [H]

Synonym: HPAG1_0285

Alternate gene names: 108562710

Gene position: 288964-289995 (Clockwise)

Preceding gene: 108562709

Following gene: 108562711

Centisome position: 18.1

GC content: 37.21

Gene sequence:

>1032_bases
ATGCAAGAAATTTTAATCCCTTTAAAAGAAAAAAGCTATAAAGTGTTTTTGGGGGAACTGCCCAAAATTGAATTGAAACA
AAAAGCGCTCATCATTAGCGATAGCATCGTGGCCGGGTTGCATTTATCGTATTTATTAAAGCGCTTGAAAGCCTTAGAAG
TCAGAGTGTGCGTGATAGAGTCCGGAGAAAAATACAAGAATTTTCATTCATTAGAGCGCATTTTAAACAACGCCTTTGAA
ATGCAATTAAACCGCCATTCTTTAATGATAGCCCTTGGTGGGGGAGTGATAAGCGATATGGTGGGGTTTGCGAGCAGTAT
TTATTTTAGGGGGATTGGTTTTATTAATATCCCTACGACTTTACTCGCTCAAGTGGATGCGAGCGTGGGGGGGAAAACAG
GGATCAATACGCCTTATGGCAAGAATTTAATCGGCTCGTTTTACCAGCCTAAAGCGGTTTATATGGATCTAGTTTTTTTA
AAAACCCTTGAAAAAAGGGAATTTCAAGCAGGGGTGGCTGAAATCATTAAAATGGCGGTGTGTTTTGATAAAAACTTGGT
AGAAACATTGGAAACAAAGGATTTAAAAGATTGTTTAGAAGAAGTAATCTTTCAAAGCGTTAATATCAAAGCTCAAGTTG
TTATGCAAGATGAAAAAGAGCAAAATATCAGGGCTGGGCTCAATTACGGGCATACCTTTGGGCATGCGATAGAAAAAGAG
ACTGATTATGAGCGATTTTTGCATGGCGAAGCGATCGCTATTGGCATGCGCATGGCTAATGATTTAGCCCTTTCTTTAGG
CATGCTCACTCTAAAAGAATACGAACGCATAGAAAATTTATTGAAAAAATTTGATTTGATATTCCATTACAAAATCACAG
ATATTCAAAAATTTTACGAACGCTTGTTTTTAGACAAAAAAAGCGAAAATAAGACAATCAAATTCATTCTGCCCAAAGGC
ATTGGAGCGTTTGAGATTGTCTCTCATATCCCTAAAGAAACGATTTTAAAGGTGTTAGAAAAATGGCATTAA

Upstream 100 bases:

>100_bases
CACACGCGCTTTTGGTGGTTTTTATCCACTAAAGTGGAAAAATTAGCGTTTTTAAACGATGATAACCCTCAAATTTTTAT
CCCTGTAGCGGAGTGAAAGA

Downstream 100 bases:

>100_bases
GGGTATTATTATTCTTTTGTTTTTTGTTTTTACAAGCAGAAGATAAAAGCCAAGAGCTATTGTCCATACAAAAACAAATG
GCTTTGGTGGATAAAAAACT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNFHSLERILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFL
KTLEKREFQAGVAEIIKMAVCFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYERLFLDKKSENKTIKFILPKG
IGAFEIVSHIPKETILKVLEKWH

Sequences:

>Translated_343_residues
MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNFHSLERILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFL
KTLEKREFQAGVAEIIKMAVCFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYERLFLDKKSENKTIKFILPKG
IGAFEIVSHIPKETILKVLEKWH
>Mature_343_residues
MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNFHSLERILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFL
KTLEKREFQAGVAEIIKMAVCFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKE
TDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYERLFLDKKSENKTIKFILPKG
IGAFEIVSHIPKETILKVLEKWH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=358, Percent_Identity=37.1508379888268, Blast_Score=218, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6320332, Length=309, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39100; Mature: 39100

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIE
CCCCEEECCCCCEEEEECCCCCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEC
SGEKYKNFHSLERILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTT
CCHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEECHHH
LLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFLKTLEKREFQAGVAEIIKMAV
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKE
HHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHCCC
TDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYE
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
RLFLDKKSENKTIKFILPKGIGAFEIVSHIPKETILKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIE
CCCCEEECCCCCEEEEECCCCCCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEC
SGEKYKNFHSLERILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTT
CCHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEECHHH
LLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFLKTLEKREFQAGVAEIIKMAV
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKE
HHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHCCC
TDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYE
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHH
RLFLDKKSENKTIKFILPKGIGAFEIVSHIPKETILKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA