Click here to switch to the map view.

The map label for this gene is 108562711

Identifier: 108562711

GI number: 108562711

Start: 289986

End: 291557

Strand: Direct

Name: 108562711

Synonym: HPAG1_0286

Alternate gene names: NA

Gene position: 289986-291557 (Clockwise)

Preceding gene: 108562710

Following gene: 108562712

Centisome position: 18.17

GC content: 36.77

Gene sequence:

>1572_bases
ATGGCATTAAGGGTATTATTATTCTTTTGTTTTTTGTTTTTACAAGCAGAAGATAAAAGCCAAGAGCTATTGTCCATACA
AAAACAAATGGCTTTGGTGGATAAAAAACTCGCCAAAGACGATAACGTGTGGTTGAAAAAATTTGAAAACTATAAGATCT
ACAATCAAATTTATACCGAAAAAGAGAGCGTGAGGCAGGAATTAAGGCACTTAAAAAACAAAAAAAGCAAGGATTTATTA
AAGATTAGCACCTTAGAGCACACCTTAAAGGCTTTAGAATCCCAGCAAAAAATGTTTGAAAGCTATGGGGTCAATCCTTT
TAAGGACTTGATAGAGCGCCCTAATATCCCTAATATCCCTAATATCGCTAACCCTATTGCGATCATTGATGGCATTTCTT
TCATTAAAAGCATGCATTTAAAGCATGAAAGTCTTAAAAATAACCAAACTGCTTTAGAAGAAGTTTTAAAGCTTTTAGAT
CAAAAACACCAGCTTTTAAACCAGTGGCACGCTTTGGATAAAAGCGCGAAATTGAGCGATGAAATTTATCAAACTCAAGC
CAAACGCTTAGAATTGCAAGGGGCTCAAAACATTTTAAAAACCACGATCGGGATTTTCCAAAAAGACAGCGATGAGGCTA
TAAGCATCGTCAAATCTCAAGTTAAAAACCAGCTTTTTAAATTGATTTATGTGTTTTTAGCCGCCCTTTTGAGCGTGGTG
TTTGCGTGGATTTTAAAAATCATTTCCAGTAAATACATTGAAAATAATGAGCGCGTCTATACCGTGAATAAAGCCATTAA
CTTCGTGAACGTGAGCGTGATCATTTTAATTTTTCTTTTTTCTTATTTAGAAAATGTTACTTACTTGGTCACGGTTTTAG
GCTTTGCGAGTGCGGGTTTAGCGATTGCGATGAAAGATTTGTTCATGAGCTTGCTTGGGTGGTTTATTATTTTGATTGGG
GGGAGCGTGCATGTGGGCGATAGGGTGCGCATCGCTAAGGGGACAGATATTTTTATTGGCGATGTGCTAGATATTTCTAT
GTTGCACATTACGATTTTAGAAGATGTAACCTTTACTACTTACACGAACAACAGGAGAGCGGGCCGGATTATTTTTGTGC
CTAATAATTACATTTTCACCACCATGTTTGCTAATTACAGCCATTTTGGGATGAAAACGGTTTGGGATGGCGTGGATTTT
TGCGTTACATTTGATTCTGATTTTAAAAAAGCTTCTAAAATTGCACTCAACATCGCTACAGAATTGTCTAAAGAATACAC
GGATATTACCTACAAACAGCTCAATAAAATGCGCGACCGGTATTCTTTAAGGAGTTTGAGTGTGAAGCCTCGATGCTTTT
TGATGCCTGAAAATAACGGGATAAAAATCTCGGTGTGGTATCAAACCAATTCGTATGCGACCTTGTCTTTAAGGAGCAAG
ATTGTGGCTGAAATCGTTGAAGCTTTTTTGAAAGAAGAAAATATCCATATCGCTTATACGACCAGCAAGTTGCTTAAAGT
GGATGCTGATTTTTTAGGCGATGGTTTTGGGAATAAAAGGGAACAAAAATGA

Upstream 100 bases:

>100_bases
GCGAAAATAAGACAATCAAATTCATTCTGCCCAAAGGCATTGGAGCGTTTGAGATTGTCTCTCATATCCCTAAAGAAACG
ATTTTAAAGGTGTTAGAAAA

Downstream 100 bases:

>100_bases
AAAAAGTCTATTTCAAAACTTTTGGGTGCAGGACGAATCTTTTTGACACGCAAGTGATGGGTGAGAATTTGAAGGACTTT
AGCGCGACCTTAGAAGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MALRVLLFFCFLFLQAEDKSQELLSIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRHLKNKKSKDLL
KISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMHLKHESLKNNQTALEEVLKLLD
QKHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLIYVFLAALLSVV
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIG
GSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDF
CVTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSK
IVAEIVEAFLKEENIHIAYTTSKLLKVDADFLGDGFGNKREQK

Sequences:

>Translated_523_residues
MALRVLLFFCFLFLQAEDKSQELLSIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRHLKNKKSKDLL
KISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMHLKHESLKNNQTALEEVLKLLD
QKHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLIYVFLAALLSVV
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIG
GSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDF
CVTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSK
IVAEIVEAFLKEENIHIAYTTSKLLKVDADFLGDGFGNKREQK
>Mature_522_residues
ALRVLLFFCFLFLQAEDKSQELLSIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTEKESVRQELRHLKNKKSKDLLK
ISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMHLKHESLKNNQTALEEVLKLLDQ
KHQLLNQWHALDKSAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLIYVFLAALLSVVF
AWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIGG
SVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTTYTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDFC
VTFDSDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKI
VAEIVEAFLKEENIHIAYTTSKLLKVDADFLGDGFGNKREQK

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 60125; Mature: 59994

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRVLLFFCFLFLQAEDKSQELLSIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTE
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHH
KESVRQELRHLKNKKSKDLLKISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
NIANPIAIIDGISFIKSMHLKHESLKNNQTALEEVLKLLDQKHQLLNQWHALDKSAKLSD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLIYVFLAALLSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGL
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AIAMKDLFMSLLGWFIILIGGSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTT
HHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCEEEEECHHHHHHHHHHHHHCCEEEE
YTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFDSDFKKASKIALNIAT
EECCCCCCEEEEECCCEEEEEEHHCCHHCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHH
ELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEHHHHHH
IVAEIVEAFLKEENIHIAYTTSKLLKVDADFLGDGFGNKREQK
HHHHHHHHHHCCCCEEEEEECHHHHHHCHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ALRVLLFFCFLFLQAEDKSQELLSIQKQMALVDKKLAKDDNVWLKKFENYKIYNQIYTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHH
KESVRQELRHLKNKKSKDLLKISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
NIANPIAIIDGISFIKSMHLKHESLKNNQTALEEVLKLLDQKHQLLNQWHALDKSAKLSD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAISIVKSQVKNQLFKLIYVFLAALLSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAWILKIISSKYIENNERVYTVNKAINFVNVSVIILIFLFSYLENVTYLVTVLGFASAGL
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AIAMKDLFMSLLGWFIILIGGSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTFTT
HHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCEEEEECHHHHHHHHHHHHHCCEEEE
YTNNRRAGRIIFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFDSDFKKASKIALNIAT
EECCCCCCEEEEECCCEEEEEEHHCCHHCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHH
ELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEHHHHHH
IVAEIVEAFLKEENIHIAYTTSKLLKVDADFLGDGFGNKREQK
HHHHHHHHHHCCCCEEEEEECHHHHHHCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]