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The map label for this gene is apr [H]

Identifier: 103488303

GI number: 103488303

Start: 2980806

End: 2982962

Strand: Reverse

Name: apr [H]

Synonym: Sala_2826

Alternate gene names: 103488303

Gene position: 2982962-2980806 (Counterclockwise)

Preceding gene: 103488306

Following gene: 103488302

Centisome position: 89.17

GC content: 70.14

Gene sequence:

>2157_bases
GTGCGCCGATCGGACGGCGTCAATTTCCACGGCGCGATCACCGCCTATCAGGCGGGGGCGAGCGGGCAGGGGGTTCTGGC
CGGAGTAATCGACGACGGGATCGACGTCGACAGCCCCGAATTTGCCGGGCGCATCTCGCCGCTGTCGGCCGACCTTGCCG
GGTCGCGCGGGATCGACGGCGAGGGCAGCCACGGCACCAATGTCGCGCAGGTGCTGCTCGGCGCAAAAAACGACGCGGGT
ACGATGGGGATCGCCTTCAACGCCGGCCTGCTCGTGCTGCGCGCCGACCAGCCGGGAAGCTGCGCGACCGAAGATCCGGC
GAACGACGAAAGCGGCTGCCGCTTTCCCGAAAGCGTGATCGCCGCAGGGCTCGACCGGGCCGTGAGCGCAGGGGCGCGCG
TCGTCAACATCTCGCTCGGCGGCGACGATCCGCCCGGCGCGACGCTCCGCGCCGCGGTGTCGCGCGCGACCGCGGCGGGG
ATCATCGTCATCCTGTCGGCGGGTAACGAGGGCGACACGACCGCGGGCGGCAACGACCCGAACAATCCCGGCCGCTTTGC
GCAGGGGCTGCGCGATGCCGGGGGCGGGCTGGTCGTCATCGCCGGTTCGGTCGATGAAAATGGCGCGATCTCCGGCTTCA
GCAATCGCGCGGGCGCCTATGCCGCCTCCTATCTGTCGGCGCTCGGCGAAGGCGTATGCTGCGTTTATGAAAATGGCGCG
CTCAAGACCGAGGGCAATTTTGTCTTTCTGCTCAACGGCACCAGCTTCGCCGCGCCGCAGATCGCCGGGGCCGTCGCGCT
GATTGCCCAGGCCTTTCCCAACCTGACCAGCCAGCAGATCGTCGAGCTGCTCTATCAATCGGCGCGCGACGCGGGGGCGG
CGGGCGACGATGCCGTCTATGGTCAGGGCATTCTCGACATCGCACGCGCCTTTCAGCCGATGGGGGCGACGACGCTGGCG
GGTAGCGCGACCGCAGTGGCGCTGGGCACGCCGCTCGGCATGTTGGGCGGCCCGATGGGCGATGCGGGGGGCGGCGCGAC
GGGGATTGTCACCGACGGTTTCGGCCGCGCCTTCAATGTCGATTTCGGGCAGTCGCTCGCGCCGCGCCGCCCCGATTTCA
AGCTGTCGGGCGCGATCGGCGGGCGCGTCCGCCAGCAGAGCGCGGCGAGCCGCTCGCTTGCACTGTCGCTCGTCACCGCG
CCCGGCGCGGGCGGCAGCGATGCGCTCGCGGGGCTGTCCTACCATGATGCGCAACGCGCGCGCACCCTCGCGGCCTCGGT
GATGATGCGGCTCGGTGCGCACACGCGTCTCGGGTTTGCGGCGGGTCGCGGGACCGGTGGCCTCCTCGCGGGTGAGCGCG
GCGAAAGCGGCCATGCGATGCTGATCGGCGACGCCGCGCACGAAGGGATCGGCTTTGCGGCCAGCCCCGGTATCGGGACA
TTGCTTCGTCATAATATCATTAATAATCAATATATTAATATATATGCCGAATCCGGGCGCGTGTCGGGTTCGCGGTGGCA
GGACGATCCGCTCCCCGGCCATAGCGCGCGCCGCGACAGCCGCTATCAGCGTATCGGCGCTTCGTGGGACGGCCGCTTCG
GTCCGCTCCGTCCGTCGCTCGGCGCGAGCTGGCTCCGCGAATCGGACAGCCTGCTCGGCGCGCGGTTCGGCCCTTTTTTC
GGCGCGGGCGGTGCGACCAGCCTGGTCGGCGATGCCGGCCTGATATTCGACGCGCCGGGCCGATGGCAAATCGGCGGCGC
CTGGCGGCAGATGTGGACGCGCCCCGACGCCCGCGGCCTCGTCGCGGGGGGCGCGCTCTGGTCGGCGGCCTTTTCGTTCG
ACATTGCCAAGGCGGGGCTGGTGCGGCCGGGCGACCGCGCCGCGCTGCGGTTCGCGCAGCCGCTGCGCGTCGCGCGCGGC
GGCATCGACCTCATGCTTCCGGTCGCCTATGATCATGGCAGCGGCCGCGCCGATTTCGGCCGCCGCATCTATAACCTCGC
CCCCACCGGCCGCGAACTGGTGGTCGAGGCGAGCTATGCGCTGCCGCTGTTCGGCGGCGACCTGATCGCCAACAGCTGGT
GGCGCCGCGATCCGGGGCATATCGCCGCCATGCCCGACGACAAAGGCGCGGCGCTGCGCTTTACGATGGGCTTCTGA

Upstream 100 bases:

>100_bases
TGCGGGGCCGTCGCCGACCCCGGCCCCGCCGCCAGCCCCGGCTCCGACGCCAACTCCGACACCCACTCCGCCGCCGGTCG
GCAATTTCGACACCGCCGAG

Downstream 100 bases:

>100_bases
TCGGCTTTAACCGCCTGCGTGCAATAACAGGGGAAGCAGGATGAAGCCTTTCCATCGCTTGTCGCTCGCGCTGGTCGGCG
CGGCGCTCGCCACGCCGCTG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MRRSDGVNFHGAITAYQAGASGQGVLAGVIDDGIDVDSPEFAGRISPLSADLAGSRGIDGEGSHGTNVAQVLLGAKNDAG
TMGIAFNAGLLVLRADQPGSCATEDPANDESGCRFPESVIAAGLDRAVSAGARVVNISLGGDDPPGATLRAAVSRATAAG
IIVILSAGNEGDTTAGGNDPNNPGRFAQGLRDAGGGLVVIAGSVDENGAISGFSNRAGAYAASYLSALGEGVCCVYENGA
LKTEGNFVFLLNGTSFAAPQIAGAVALIAQAFPNLTSQQIVELLYQSARDAGAAGDDAVYGQGILDIARAFQPMGATTLA
GSATAVALGTPLGMLGGPMGDAGGGATGIVTDGFGRAFNVDFGQSLAPRRPDFKLSGAIGGRVRQQSAASRSLALSLVTA
PGAGGSDALAGLSYHDAQRARTLAASVMMRLGAHTRLGFAAGRGTGGLLAGERGESGHAMLIGDAAHEGIGFAASPGIGT
LLRHNIINNQYINIYAESGRVSGSRWQDDPLPGHSARRDSRYQRIGASWDGRFGPLRPSLGASWLRESDSLLGARFGPFF
GAGGATSLVGDAGLIFDAPGRWQIGGAWRQMWTRPDARGLVAGGALWSAAFSFDIAKAGLVRPGDRAALRFAQPLRVARG
GIDLMLPVAYDHGSGRADFGRRIYNLAPTGRELVVEASYALPLFGGDLIANSWWRRDPGHIAAMPDDKGAALRFTMGF

Sequences:

>Translated_718_residues
MRRSDGVNFHGAITAYQAGASGQGVLAGVIDDGIDVDSPEFAGRISPLSADLAGSRGIDGEGSHGTNVAQVLLGAKNDAG
TMGIAFNAGLLVLRADQPGSCATEDPANDESGCRFPESVIAAGLDRAVSAGARVVNISLGGDDPPGATLRAAVSRATAAG
IIVILSAGNEGDTTAGGNDPNNPGRFAQGLRDAGGGLVVIAGSVDENGAISGFSNRAGAYAASYLSALGEGVCCVYENGA
LKTEGNFVFLLNGTSFAAPQIAGAVALIAQAFPNLTSQQIVELLYQSARDAGAAGDDAVYGQGILDIARAFQPMGATTLA
GSATAVALGTPLGMLGGPMGDAGGGATGIVTDGFGRAFNVDFGQSLAPRRPDFKLSGAIGGRVRQQSAASRSLALSLVTA
PGAGGSDALAGLSYHDAQRARTLAASVMMRLGAHTRLGFAAGRGTGGLLAGERGESGHAMLIGDAAHEGIGFAASPGIGT
LLRHNIINNQYINIYAESGRVSGSRWQDDPLPGHSARRDSRYQRIGASWDGRFGPLRPSLGASWLRESDSLLGARFGPFF
GAGGATSLVGDAGLIFDAPGRWQIGGAWRQMWTRPDARGLVAGGALWSAAFSFDIAKAGLVRPGDRAALRFAQPLRVARG
GIDLMLPVAYDHGSGRADFGRRIYNLAPTGRELVVEASYALPLFGGDLIANSWWRRDPGHIAAMPDDKGAALRFTMGF
>Mature_718_residues
MRRSDGVNFHGAITAYQAGASGQGVLAGVIDDGIDVDSPEFAGRISPLSADLAGSRGIDGEGSHGTNVAQVLLGAKNDAG
TMGIAFNAGLLVLRADQPGSCATEDPANDESGCRFPESVIAAGLDRAVSAGARVVNISLGGDDPPGATLRAAVSRATAAG
IIVILSAGNEGDTTAGGNDPNNPGRFAQGLRDAGGGLVVIAGSVDENGAISGFSNRAGAYAASYLSALGEGVCCVYENGA
LKTEGNFVFLLNGTSFAAPQIAGAVALIAQAFPNLTSQQIVELLYQSARDAGAAGDDAVYGQGILDIARAFQPMGATTLA
GSATAVALGTPLGMLGGPMGDAGGGATGIVTDGFGRAFNVDFGQSLAPRRPDFKLSGAIGGRVRQQSAASRSLALSLVTA
PGAGGSDALAGLSYHDAQRARTLAASVMMRLGAHTRLGFAAGRGTGGLLAGERGESGHAMLIGDAAHEGIGFAASPGIGT
LLRHNIINNQYINIYAESGRVSGSRWQDDPLPGHSARRDSRYQRIGASWDGRFGPLRPSLGASWLRESDSLLGARFGPFF
GAGGATSLVGDAGLIFDAPGRWQIGGAWRQMWTRPDARGLVAGGALWSAAFSFDIAKAGLVRPGDRAALRFAQPLRVARG
GIDLMLPVAYDHGSGRADFGRRIYNLAPTGRELVVEASYALPLFGGDLIANSWWRRDPGHIAAMPDDKGAALRFTMGF

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 73162; Mature: 73162

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSDGVNFHGAITAYQAGASGQGVLAGVIDDGIDVDSPEFAGRISPLSADLAGSRGIDG
CCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
EGSHGTNVAQVLLGAKNDAGTMGIAFNAGLLVLRADQPGSCATEDPANDESGCRFPESVI
CCCCCCCHHHHEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHH
AAGLDRAVSAGARVVNISLGGDDPPGATLRAAVSRATAAGIIVILSAGNEGDTTAGGNDP
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
NNPGRFAQGLRDAGGGLVVIAGSVDENGAISGFSNRAGAYAASYLSALGEGVCCVYENGA
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCC
LKTEGNFVFLLNGTSFAAPQIAGAVALIAQAFPNLTSQQIVELLYQSARDAGAAGDDAVY
EEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GQGILDIARAFQPMGATTLAGSATAVALGTPLGMLGGPMGDAGGGATGIVTDGFGRAFNV
CCHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHCCCCCCCCCCEEEEEECCCCCEEEC
DFGQSLAPRRPDFKLSGAIGGRVRQQSAASRSLALSLVTAPGAGGSDALAGLSYHDAQRA
CCCCCCCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHCCCCHHHHHHH
RTLAASVMMRLGAHTRLGFAAGRGTGGLLAGERGESGHAMLIGDAAHEGIGFAASPGIGT
HHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCEECCCCHHH
LLRHNIINNQYINIYAESGRVSGSRWQDDPLPGHSARRDSRYQRIGASWDGRFGPLRPSL
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GASWLRESDSLLGARFGPFFGAGGATSLVGDAGLIFDAPGRWQIGGAWRQMWTRPDARGL
CHHHHHHCCHHHHCCCCCCCCCCCCHHHHCCCCEEEECCCCEEECHHHHHHHCCCCCCCE
VAGGALWSAAFSFDIAKAGLVRPGDRAALRFAQPLRVARGGIDLMLPVAYDHGSGRADFG
EECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHH
RRIYNLAPTGRELVVEASYALPLFGGDLIANSWWRRDPGHIAAMPDDKGAALRFTMGF
HHHEECCCCCCEEEEEEEEECEEECCHHHHCCCCCCCCCCEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MRRSDGVNFHGAITAYQAGASGQGVLAGVIDDGIDVDSPEFAGRISPLSADLAGSRGIDG
CCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
EGSHGTNVAQVLLGAKNDAGTMGIAFNAGLLVLRADQPGSCATEDPANDESGCRFPESVI
CCCCCCCHHHHEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHH
AAGLDRAVSAGARVVNISLGGDDPPGATLRAAVSRATAAGIIVILSAGNEGDTTAGGNDP
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
NNPGRFAQGLRDAGGGLVVIAGSVDENGAISGFSNRAGAYAASYLSALGEGVCCVYENGA
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCC
LKTEGNFVFLLNGTSFAAPQIAGAVALIAQAFPNLTSQQIVELLYQSARDAGAAGDDAVY
EEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GQGILDIARAFQPMGATTLAGSATAVALGTPLGMLGGPMGDAGGGATGIVTDGFGRAFNV
CCHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHCCCCCCCCCCEEEEEECCCCCEEEC
DFGQSLAPRRPDFKLSGAIGGRVRQQSAASRSLALSLVTAPGAGGSDALAGLSYHDAQRA
CCCCCCCCCCCCEEEECCCCCHHHHHHHHCCEEEEEEEECCCCCCHHHHCCCCHHHHHHH
RTLAASVMMRLGAHTRLGFAAGRGTGGLLAGERGESGHAMLIGDAAHEGIGFAASPGIGT
HHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCEECCCCHHH
LLRHNIINNQYINIYAESGRVSGSRWQDDPLPGHSARRDSRYQRIGASWDGRFGPLRPSL
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GASWLRESDSLLGARFGPFFGAGGATSLVGDAGLIFDAPGRWQIGGAWRQMWTRPDARGL
CHHHHHHCCHHHHCCCCCCCCCCCCHHHHCCCCEEEECCCCEEECHHHHHHHCCCCCCCE
VAGGALWSAAFSFDIAKAGLVRPGDRAALRFAQPLRVARGGIDLMLPVAYDHGSGRADFG
EECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHH
RRIYNLAPTGRELVVEASYALPLFGGDLIANSWWRRDPGHIAAMPDDKGAALRFTMGF
HHHEECCCCCCEEEEEEEEECEEECCHHHHCCCCCCCCCCEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6420308; 9826175 [H]