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The map label for this gene is ffh [H]

Identifier: 103488205

GI number: 103488205

Start: 2873285

End: 2874739

Strand: Reverse

Name: ffh [H]

Synonym: Sala_2728

Alternate gene names: 103488205

Gene position: 2874739-2873285 (Counterclockwise)

Preceding gene: 103488212

Following gene: 103488204

Centisome position: 85.94

GC content: 66.19

Gene sequence:

>1455_bases
ATGTTCGACAGTCTGAGCAATCGGCTTGGCGATGTTTTCGGGAAGCTCCGCGGTCGCGGCGCGCTGACCGAGGCCGACGT
GCGCGCCGCGATGCGCGAGGTACGAATCGCGTTGCTCGAGGCCGATGTCGCGCTGCCCGTCGTGCGCAGCTTCGTCGATC
AGGTCACCGAACTCGCGATCGGCCAGAATGTCCTGCGCTCGGTCACGCCGGGGCAGCAGGTGGTCAAGATCGTCAATGAC
GCGCTGACCGAAATGCTCGGCTCCGAAACCGCCGAACTCGATCTGGCGGTCGCCCCGCCCGCGGTGATCATGATGGTCGG
CCTTCAGGGATCGGGTAAGACCACCACGACGGCAAAGATCGCCAAGCGTCTCAGGGAAAAGGAGCGCAAGAAGGTGCTGA
TGGCGTCGCTCGACGTCAATCGCCCCGCCGCGCAGGAACAGCTTGCCGTGCTTGGTCAGCAGATCGATGTCGCGACCTTG
CCGATCATTGTCGGCCAGCAGCCGGTCGAAATCGCGCAGCGCGCGTTGCAGGCCGCGAAGCTTCAGGGCTATGACGTGCT
GATGCTCGACACTGCGGGCCGGCTCCACGTCGACCAGCAACTGATGGACGAGATGCAGGCGGTGTCGCGCACGGCGAACC
CGGCCGAAACATTGCTCGTCGTCGACAGCCTGACCGGTCAGGACGCGGTCCAGGTCGCGCAGCGCTTCACGGATCAGGTG
CCGCTCACCGGGGTCGTCCTGACGCGCATGGACGGCGATGCGCGCGGCGGCGCCGCGCTGTCGATGCGCGCGGTCACCGG
CAAACCGATCAAGTTCGCGGGCACGGGCGAGAAACTCGACGGGCTCGAGTTGTTCCAGCCGTCGCGTATCGCGGGCCGCA
TCCTTGGCATGGGCGACGTGGTCAGCCTGGTCGAGCGCGCCGCCGAAACGATCCAGGCGGACGAAGCCGAAGCGATGGCG
GCCAAGATGGCCAAGGGTCAGTTCGACCTCAACGACCTTCGCACGCAGCTGAATCAGATGCGCCGCATGGGAGGCCTCGG
CGCGCTCGCGGGGATGATCCCGGGGATCAAGAAGGCGCAGGCGGCGATGGCCGCGGGCGGCGCCGACGACAAGATGCTCG
TTCACTTCGATGCGATCATGGGGTCGATGACGCCGAAGGAGCGCGCGAAGCCCGAAATCATCAACGCCAAGCGCAAGATC
CGCATCGCCAACGGGTCGGGCACGACGGTGCAACAGGTGAACAAGGTGCTGAAGATGCACCAGGAAATGTCCACCGCGAT
GAAGAAGATCCGCAAGATGGGCGGCCTCAAGGGCCTCGGCGCGCTGTTCGGGCGCGGCGGCGGCATTCCCGGAATGCCGG
GGCTTGGCGGCGGCGGAATGGGAGGCGGTCTGCCCGGCCTCGGTGGCGGCGGCATGCCCCCCGATCTCGCCAACCTGCTC
AACAAGAAGAAATGA

Upstream 100 bases:

>100_bases
ATCCGCGACGGAACATCTGTCCACGGATAGCCGCTGGTTGGCGAGGTTTCGCTCACCGGCGTCTTTTGCGTTGCGGGCTG
TCAGAAGGGATTTTGGGCGC

Downstream 100 bases:

>100_bases
TTTAACCCGCATTTGAAGATCAGACGTAGAAGGAATTATTCATGGCTACCTCCATTCGCCTCGCACGCGGCGGTTCGAAA
AAGCGTCCCTATTACAAGAT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MFDSLSNRLGDVFGKLRGRGALTEADVRAAMREVRIALLEADVALPVVRSFVDQVTELAIGQNVLRSVTPGQQVVKIVND
ALTEMLGSETAELDLAVAPPAVIMMVGLQGSGKTTTTAKIAKRLREKERKKVLMASLDVNRPAAQEQLAVLGQQIDVATL
PIIVGQQPVEIAQRALQAAKLQGYDVLMLDTAGRLHVDQQLMDEMQAVSRTANPAETLLVVDSLTGQDAVQVAQRFTDQV
PLTGVVLTRMDGDARGGAALSMRAVTGKPIKFAGTGEKLDGLELFQPSRIAGRILGMGDVVSLVERAAETIQADEAEAMA
AKMAKGQFDLNDLRTQLNQMRRMGGLGALAGMIPGIKKAQAAMAAGGADDKMLVHFDAIMGSMTPKERAKPEIINAKRKI
RIANGSGTTVQQVNKVLKMHQEMSTAMKKIRKMGGLKGLGALFGRGGGIPGMPGLGGGGMGGGLPGLGGGGMPPDLANLL
NKKK

Sequences:

>Translated_484_residues
MFDSLSNRLGDVFGKLRGRGALTEADVRAAMREVRIALLEADVALPVVRSFVDQVTELAIGQNVLRSVTPGQQVVKIVND
ALTEMLGSETAELDLAVAPPAVIMMVGLQGSGKTTTTAKIAKRLREKERKKVLMASLDVNRPAAQEQLAVLGQQIDVATL
PIIVGQQPVEIAQRALQAAKLQGYDVLMLDTAGRLHVDQQLMDEMQAVSRTANPAETLLVVDSLTGQDAVQVAQRFTDQV
PLTGVVLTRMDGDARGGAALSMRAVTGKPIKFAGTGEKLDGLELFQPSRIAGRILGMGDVVSLVERAAETIQADEAEAMA
AKMAKGQFDLNDLRTQLNQMRRMGGLGALAGMIPGIKKAQAAMAAGGADDKMLVHFDAIMGSMTPKERAKPEIINAKRKI
RIANGSGTTVQQVNKVLKMHQEMSTAMKKIRKMGGLKGLGALFGRGGGIPGMPGLGGGGMGGGLPGLGGGGMPPDLANLL
NKKK
>Mature_484_residues
MFDSLSNRLGDVFGKLRGRGALTEADVRAAMREVRIALLEADVALPVVRSFVDQVTELAIGQNVLRSVTPGQQVVKIVND
ALTEMLGSETAELDLAVAPPAVIMMVGLQGSGKTTTTAKIAKRLREKERKKVLMASLDVNRPAAQEQLAVLGQQIDVATL
PIIVGQQPVEIAQRALQAAKLQGYDVLMLDTAGRLHVDQQLMDEMQAVSRTANPAETLLVVDSLTGQDAVQVAQRFTDQV
PLTGVVLTRMDGDARGGAALSMRAVTGKPIKFAGTGEKLDGLELFQPSRIAGRILGMGDVVSLVERAAETIQADEAEAMA
AKMAKGQFDLNDLRTQLNQMRRMGGLGALAGMIPGIKKAQAAMAAGGADDKMLVHFDAIMGSMTPKERAKPEIINAKRKI
RIANGSGTTVQQVNKVLKMHQEMSTAMKKIRKMGGLKGLGALFGRGGGIPGMPGLGGGGMGGGLPGLGGGGMPPDLANLL
NKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=439, Percent_Identity=32.8018223234624, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI226371618, Length=407, Percent_Identity=32.4324324324324, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=35.2201257861635, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI23308697, Length=314, Percent_Identity=28.343949044586, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI295424842, Length=308, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=55.188679245283, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1789874, Length=252, Percent_Identity=35.7142857142857, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=455, Percent_Identity=30.7692307692308, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI193206261, Length=256, Percent_Identity=32.03125, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325345, Length=463, Percent_Identity=31.7494600431965, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6320498, Length=321, Percent_Identity=26.4797507788162, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17647949, Length=443, Percent_Identity=30.4740406320542, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24641198, Length=308, Percent_Identity=26.9480519480519, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50975; Mature: 50975

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS01199 RIBOSOMAL_L1 ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSLSNRLGDVFGKLRGRGALTEADVRAAMREVRIALLEADVALPVVRSFVDQVTELAI
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQNVLRSVTPGQQVVKIVNDALTEMLGSETAELDLAVAPPAVIMMVGLQGSGKTTTTAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHEEEEECCCCCCCHHHHHH
AKRLREKERKKVLMASLDVNRPAAQEQLAVLGQQIDVATLPIIVGQQPVEIAQRALQAAK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECEEECCCCHHHHHHHHHHHH
LQGYDVLMLDTAGRLHVDQQLMDEMQAVSRTANPAETLLVVDSLTGQDAVQVAQRFTDQV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHCCC
PLTGVVLTRMDGDARGGAALSMRAVTGKPIKFAGTGEKLDGLELFQPSRIAGRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEECCCCCCCCCHHHCCCHHHHHHHCCHHHH
VSLVERAAETIQADEAEAMAAKMAKGQFDLNDLRTQLNQMRRMGGLGALAGMIPGIKKAQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
AAMAAGGADDKMLVHFDAIMGSMTPKERAKPEIINAKRKIRIANGSGTTVQQVNKVLKMH
HHHHCCCCCCCEEEEHHHHHCCCCCHHHCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHH
QEMSTAMKKIRKMGGLKGLGALFGRGGGIPGMPGLGGGGMGGGLPGLGGGGMPPDLANLL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
NKKK
CCCC
>Mature Secondary Structure
MFDSLSNRLGDVFGKLRGRGALTEADVRAAMREVRIALLEADVALPVVRSFVDQVTELAI
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQNVLRSVTPGQQVVKIVNDALTEMLGSETAELDLAVAPPAVIMMVGLQGSGKTTTTAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHEEEEECCCCCCCHHHHHH
AKRLREKERKKVLMASLDVNRPAAQEQLAVLGQQIDVATLPIIVGQQPVEIAQRALQAAK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECEEECCCCHHHHHHHHHHHH
LQGYDVLMLDTAGRLHVDQQLMDEMQAVSRTANPAETLLVVDSLTGQDAVQVAQRFTDQV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHHHHCCC
PLTGVVLTRMDGDARGGAALSMRAVTGKPIKFAGTGEKLDGLELFQPSRIAGRILGMGDV
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEECCCCCCCCCHHHCCCHHHHHHHCCHHHH
VSLVERAAETIQADEAEAMAAKMAKGQFDLNDLRTQLNQMRRMGGLGALAGMIPGIKKAQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
AAMAAGGADDKMLVHFDAIMGSMTPKERAKPEIINAKRKIRIANGSGTTVQQVNKVLKMH
HHHHCCCCCCCEEEEHHHHHCCCCCHHHCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHH
QEMSTAMKKIRKMGGLKGLGALFGRGGGIPGMPGLGGGGMGGGLPGLGGGGMPPDLANLL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
NKKK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]