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The map label for this gene is celR [H]

Identifier: 103487571

GI number: 103487571

Start: 2195553

End: 2196569

Strand: Direct

Name: celR [H]

Synonym: Sala_2090

Alternate gene names: 103487571

Gene position: 2195553-2196569 (Clockwise)

Preceding gene: 103487570

Following gene: 103487572

Centisome position: 65.63

GC content: 71.78

Gene sequence:

>1017_bases
ATGACCGCAAAGATGCTGCGCCCGACTTCGTTCGACGTCGCCGAGCGCGCGGGCGTATCGCAATCGACCGTCTCGCGCGC
GCTTCGCAACTCGCCCGGCGTCAACGCCGAAACGCGCGCGCGCGTCGCCGCCGCCGCGCGCGAACTGGGCTATGTCGTCG
ACCGCCACGCCTCGTCGCTGCGCCTCAAAAGCAGCGAGACGATCGCGCTCGTCACCATCTGCCGCCCCGGCGAGGACAGG
AGCGCAATCAATCCCTTCTACTTCGCGCTGCTCGGCAGCATCGCCGCCGCAACGTCGGCGCGCGGCTTCAACCTGCTCGT
CAGCTTTCAGGAAAATCCCGACAATTTCCGCGCCGATTTCGTCGCCTCGGGGCTCGCCGACGCGATGATCGTCATCGGCA
CCACCAGCAACCGCGCCGCCTGGGATTATTTCGCAGAGGCGCAGGCGTCGGGGCTCGACTTCGTCTGCTGGGGCAGCCCC
GGCAGCCCCTTTCACTGGATGCGCAGCGAAAATGACGAGGGCGGCCAGATGGCGGCCAACCATCTGGTGGGGCTCGGTCG
CCGCCGCATCGCCTTCGTCGGGCCGCAGCAATCGCCGCAGCGCCAGTTCGACGAGCGCCGCGACGGCTTCACCGCCGCCC
TCGCCGCGCACGGCCTGACGCCCATCGTCGCCGAGCCGCCGCCCGCCACCGACCGCCACGCACAGGGCGTCGCCGCCGCG
CAGGCGCTGCTCGCCGCGCACCCCGACGTCGACGCCATCTTCGCGGCCAGCGACATGCTCGCGCTCGGCGTGCTGCAAGG
CCTCAAGGACGCCGGCCGCCGCGTCCCGCACGATGTCGCGCTGATCGGCTTTGACGGCATCCGCGCCGGCACCCTCGCCG
ACCCCGCGCTGACCACGCTCGAGCCCGACCTCGACGCCGCGGGCGAGGCGCTCGTCGCGATGGCGCTGGAGGATGACGAG
CGCACGCGCAGCGGCACGCGCGTTCCCGTGCGCCTCGTCCTGCGCGGCACCGCCTGA

Upstream 100 bases:

>100_bases
GATGCCGCCTCGGCGACCGGCGCGACCGCAGCGTCGCCCGCACGTTGACAAGCCGCGTCCTCCCGGCGAGAGACGGGCCG
GGAGGGGGAGAGACGCCGCC

Downstream 100 bases:

>100_bases
GCCATCTTCGCCCCACGTCCCGGCACGCGCGCGCCGGACCGCACATCATAGAGCGGCAGGCGGCTCGTCCGACCGGCGGT
GCGGATTGCATGGCCGTCCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTAKMLRPTSFDVAERAGVSQSTVSRALRNSPGVNAETRARVAAAARELGYVVDRHASSLRLKSSETIALVTICRPGEDR
SAINPFYFALLGSIAAATSARGFNLLVSFQENPDNFRADFVASGLADAMIVIGTTSNRAAWDYFAEAQASGLDFVCWGSP
GSPFHWMRSENDEGGQMAANHLVGLGRRRIAFVGPQQSPQRQFDERRDGFTAALAAHGLTPIVAEPPPATDRHAQGVAAA
QALLAAHPDVDAIFAASDMLALGVLQGLKDAGRRVPHDVALIGFDGIRAGTLADPALTTLEPDLDAAGEALVAMALEDDE
RTRSGTRVPVRLVLRGTA

Sequences:

>Translated_338_residues
MTAKMLRPTSFDVAERAGVSQSTVSRALRNSPGVNAETRARVAAAARELGYVVDRHASSLRLKSSETIALVTICRPGEDR
SAINPFYFALLGSIAAATSARGFNLLVSFQENPDNFRADFVASGLADAMIVIGTTSNRAAWDYFAEAQASGLDFVCWGSP
GSPFHWMRSENDEGGQMAANHLVGLGRRRIAFVGPQQSPQRQFDERRDGFTAALAAHGLTPIVAEPPPATDRHAQGVAAA
QALLAAHPDVDAIFAASDMLALGVLQGLKDAGRRVPHDVALIGFDGIRAGTLADPALTTLEPDLDAAGEALVAMALEDDE
RTRSGTRVPVRLVLRGTA
>Mature_337_residues
TAKMLRPTSFDVAERAGVSQSTVSRALRNSPGVNAETRARVAAAARELGYVVDRHASSLRLKSSETIALVTICRPGEDRS
AINPFYFALLGSIAAATSARGFNLLVSFQENPDNFRADFVASGLADAMIVIGTTSNRAAWDYFAEAQASGLDFVCWGSPG
SPFHWMRSENDEGGQMAANHLVGLGRRRIAFVGPQQSPQRQFDERRDGFTAALAAHGLTPIVAEPPPATDRHAQGVAAAQ
ALLAAHPDVDAIFAASDMLALGVLQGLKDAGRRVPHDVALIGFDGIRAGTLADPALTTLEPDLDAAGEALVAMALEDDER
TRSGTRVPVRLVLRGTA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=343, Percent_Identity=29.1545189504373, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787948, Length=314, Percent_Identity=27.3885350318471, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788474, Length=309, Percent_Identity=28.4789644012945, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI48994940, Length=308, Percent_Identity=25.974025974026, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787906, Length=276, Percent_Identity=31.1594202898551, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789456, Length=344, Percent_Identity=26.1627906976744, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787580, Length=296, Percent_Identity=26.3513513513513, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789068, Length=303, Percent_Identity=27.3927392739274, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790192, Length=233, Percent_Identity=30.4721030042918, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789202, Length=303, Percent_Identity=26.7326732673267, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35785; Mature: 35653

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKMLRPTSFDVAERAGVSQSTVSRALRNSPGVNAETRARVAAAARELGYVVDRHASSL
CCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHE
RLKSSETIALVTICRPGEDRSAINPFYFALLGSIAAATSARGFNLLVSFQENPDNFRADF
EECCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
VASGLADAMIVIGTTSNRAAWDYFAEAQASGLDFVCWGSPGSPFHWMRSENDEGGQMAAN
HHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
HLVGLGRRRIAFVGPQQSPQRQFDERRDGFTAALAAHGLTPIVAEPPPATDRHAQGVAAA
HHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCHHHHHHHH
QALLAAHPDVDAIFAASDMLALGVLQGLKDAGRRVPHDVALIGFDGIRAGTLADPALTTL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHC
EPDLDAAGEALVAMALEDDERTRSGTRVPVRLVLRGTA
CCCCCCCCCEEEEEEECCCHHHCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TAKMLRPTSFDVAERAGVSQSTVSRALRNSPGVNAETRARVAAAARELGYVVDRHASSL
CCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHE
RLKSSETIALVTICRPGEDRSAINPFYFALLGSIAAATSARGFNLLVSFQENPDNFRADF
EECCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
VASGLADAMIVIGTTSNRAAWDYFAEAQASGLDFVCWGSPGSPFHWMRSENDEGGQMAAN
HHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
HLVGLGRRRIAFVGPQQSPQRQFDERRDGFTAALAAHGLTPIVAEPPPATDRHAQGVAAA
HHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCHHHHHHHH
QALLAAHPDVDAIFAASDMLALGVLQGLKDAGRRVPHDVALIGFDGIRAGTLADPALTTL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHC
EPDLDAAGEALVAMALEDDERTRSGTRVPVRLVLRGTA
CCCCCCCCCEEEEEEECCCHHHCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]