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The map label for this gene is ykoW [H]

Identifier: 103487256

GI number: 103487256

Start: 1867820

End: 1870111

Strand: Direct

Name: ykoW [H]

Synonym: Sala_1771

Alternate gene names: 103487256

Gene position: 1867820-1870111 (Clockwise)

Preceding gene: 103487255

Following gene: 103487258

Centisome position: 55.84

GC content: 61.3

Gene sequence:

>2292_bases
GTGCCCATCCCGGTCAAGAGTCTGATCATCAGCTGGCGCAGCATCGGCTTGTCGCTGTTGATTGCCCTCGTAGTGGGCAT
AACGGCGGCCGGCGAAGTGGCGGACCGCGTGCTCGACGCCGTGGTGGGGCGTCTCGCGATGCGTCCGGTAAGCGGCGAAG
TGGTGATTGTAGCGCTGGACGAGCGCACAATTACGCAATCGCCCAGCCGCAACTTCTCGATGACCCAATATGCAAATGTC
GTCGAAGCCGTGGACAAGGCTGGAGCGAGGCGCCTTTTCATAGACTTCTATTTCGACCGGCGCGAGGCCGACCATGATTT
TCCACGTTTCGTCAGTGCGGTGAAGAATATGGGCGACCGCATTGTCCTCGCGGTTTCGACACGTCAGGTTCCCGGTCGCG
AAGATAAGGTCACAACATTCCCCAGCAAGAAGTTCGGTCCCGATGTTCCCATCGCAAGCATCGCTGTAGAAAGCGAGTTT
TGGCAGGTATGGCGCGTGCCAATTGCGTATCGCGCCGAAGGAAAGTTGCTGCCGACCTTTGCATCTATCATGGCAGGGAA
GAGCAGCGATACACCCAAAAGTTTTCGTCTGGACCTGAGCTACGACACTCGCACGATTACGGAGTATAGTGCCGCAGACT
TGCTTTCAGGCAAGATCGGAGCACGCGAACTGGCTGGAAAGGATGTGATATTCGCGCCAACGGCACCGAGCTTTCAGGAT
TATTTCTATTTGCCTGGCCATGATCGCGTCCCTGGAGGTTTCATTCACGTCATCGCGGCCGAAACGTTGAAGCGGGGCGA
CCCGATCGATATCGGTTGGCTACCACCGTTGCTCGTCGCAATCGCGCTGACGGGGATAACGCTTCTTCGGCGCTTCCAGC
GTGCCGTTCTGCCCGCAATAATCGGCACGATCGTTATCCTGATCGGTGGCAAGATCGTACTTGGGACCATGCTTGTGACG
TCATGGATCGGCGCGGCACTAGTCTACGTCGCGGCGATCGCGACCAACGTCTCGCGAACCCGCAGGCGTAGTTCGGCGCA
GCGCGAAAATCCGGTCTCTGGGCTGCCCAACTTCGAGGCGCTCCGTTCGCTCCCGCCCTTCGGCAGCGCGACGGTGATTG
CCGCCAAGGTCGTCAATTTCGAGGATCTCGCTGCCTTCATTCCGGGCGACGGCATTGGCAAGCTGGTCGAACAGGTCACG
CGCCGCCTCCAGCTCGCGTCGCAGGGCACGACATTGCACCACGACCTCGACGGCACTTTCGCCTGGCTCGTGCCCTATTA
TCAGCACAGCCAGATCGAGGGCCAGCTCGCCGGGCTCGCCGCGCTGTTCAACGCACCGCTGACGATCGGCGACCTGCGCG
TCGACGTCGCGATCGCCTTCGGGGTCAATGACGAGTTCGAGGGGTCGAACGCCCAGCGGCTCGCCGCCGCGCTCGTCGCC
GCCGAGCGCGCGATCCGCACCCGCGCATTGTGGACCAAATATACGCCGCGGCAAAAGGACGGCGCCGGCTGGCAGCTGTC
CTTCCACTCGCAGCTCGAGGATGCGCTCACCGGCGGCGACATCTGGGTCGCCTTCCAGCCGCAATATGAGATCGCCACCC
GTCGTCTGGTCGGGGTCGAGGCGCTTGCGCGCTGGACGCACCCGACGCGCGGCCCCATTCCGCCCGATGAATTCATCATT
CAGGCCGAAAAAAGCCAGGACATCTATCGTCTGACGCTGTTCGTGATGGATCAGGCGATCCGCTCGGCGGCGGAGCTGCG
CGGACGCGGTGTCCATATCAACATGTCGGTCAACCTGTCGGCGACCCTGCTCGATCACAGCGATCTGGTCGGGACGATCC
GCGTCATGCTCACCGCGCATCATCTGCCGCCCGAAACCCTGACGATCGAGATCACCGAAACCGCGCAGATCGAGAACAGC
CGGCAGGCGCGCCAGACGCTGGCACAGCTGCGCCGGACGGGCATCCGCCTGTCGATCGACGATTATGGCACCGGCCAGTC
GAACCTCGAATATCTGACCGAGATCGAAGCCGACGAGATCAAGATCGACAAGCGATTCGTTTCGACGATGCACGATTCGC
AGCGCAACCGCGAAGTCGTCAAATCGACGATCGATCTGGCGCACCGGCTCGGTGCTGTCGCGGTTGCCGAAGGCATTGAA
GATGCAGAAACAATGGCCCTGCTCGCCAGCCTCGGCTGCGATGTCGGCCAAGGCTATCATCTTGGAAAACCACAATTGTT
TTCCGACCTCATCGCCGCCCTGACGACCCCGCCCCACAGCCGCTCCGCATAA

Upstream 100 bases:

>100_bases
TGCGCCTTCCGCCGCGCCGGAAAGCGCAGGATTCCGTTCATGATTAACGCGATGATAACCGACTGGGACTAGACGCAACG
GGCAATTGCTGGAGACGTGC

Downstream 100 bases:

>100_bases
TCGCCAGAATGGCGACAATCTTTATAGTTAAGACTCGATTTACCTTATTAATTAAGGTATACGCCCTGTTAACTGTTCTG
CGTGGGCAGTCTTATCAGGA

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MPIPVKSLIISWRSIGLSLLIALVVGITAAGEVADRVLDAVVGRLAMRPVSGEVVIVALDERTITQSPSRNFSMTQYANV
VEAVDKAGARRLFIDFYFDRREADHDFPRFVSAVKNMGDRIVLAVSTRQVPGREDKVTTFPSKKFGPDVPIASIAVESEF
WQVWRVPIAYRAEGKLLPTFASIMAGKSSDTPKSFRLDLSYDTRTITEYSAADLLSGKIGARELAGKDVIFAPTAPSFQD
YFYLPGHDRVPGGFIHVIAAETLKRGDPIDIGWLPPLLVAIALTGITLLRRFQRAVLPAIIGTIVILIGGKIVLGTMLVT
SWIGAALVYVAAIATNVSRTRRRSSAQRENPVSGLPNFEALRSLPPFGSATVIAAKVVNFEDLAAFIPGDGIGKLVEQVT
RRLQLASQGTTLHHDLDGTFAWLVPYYQHSQIEGQLAGLAALFNAPLTIGDLRVDVAIAFGVNDEFEGSNAQRLAAALVA
AERAIRTRALWTKYTPRQKDGAGWQLSFHSQLEDALTGGDIWVAFQPQYEIATRRLVGVEALARWTHPTRGPIPPDEFII
QAEKSQDIYRLTLFVMDQAIRSAAELRGRGVHINMSVNLSATLLDHSDLVGTIRVMLTAHHLPPETLTIEITETAQIENS
RQARQTLAQLRRTGIRLSIDDYGTGQSNLEYLTEIEADEIKIDKRFVSTMHDSQRNREVVKSTIDLAHRLGAVAVAEGIE
DAETMALLASLGCDVGQGYHLGKPQLFSDLIAALTTPPHSRSA

Sequences:

>Translated_763_residues
MPIPVKSLIISWRSIGLSLLIALVVGITAAGEVADRVLDAVVGRLAMRPVSGEVVIVALDERTITQSPSRNFSMTQYANV
VEAVDKAGARRLFIDFYFDRREADHDFPRFVSAVKNMGDRIVLAVSTRQVPGREDKVTTFPSKKFGPDVPIASIAVESEF
WQVWRVPIAYRAEGKLLPTFASIMAGKSSDTPKSFRLDLSYDTRTITEYSAADLLSGKIGARELAGKDVIFAPTAPSFQD
YFYLPGHDRVPGGFIHVIAAETLKRGDPIDIGWLPPLLVAIALTGITLLRRFQRAVLPAIIGTIVILIGGKIVLGTMLVT
SWIGAALVYVAAIATNVSRTRRRSSAQRENPVSGLPNFEALRSLPPFGSATVIAAKVVNFEDLAAFIPGDGIGKLVEQVT
RRLQLASQGTTLHHDLDGTFAWLVPYYQHSQIEGQLAGLAALFNAPLTIGDLRVDVAIAFGVNDEFEGSNAQRLAAALVA
AERAIRTRALWTKYTPRQKDGAGWQLSFHSQLEDALTGGDIWVAFQPQYEIATRRLVGVEALARWTHPTRGPIPPDEFII
QAEKSQDIYRLTLFVMDQAIRSAAELRGRGVHINMSVNLSATLLDHSDLVGTIRVMLTAHHLPPETLTIEITETAQIENS
RQARQTLAQLRRTGIRLSIDDYGTGQSNLEYLTEIEADEIKIDKRFVSTMHDSQRNREVVKSTIDLAHRLGAVAVAEGIE
DAETMALLASLGCDVGQGYHLGKPQLFSDLIAALTTPPHSRSA
>Mature_762_residues
PIPVKSLIISWRSIGLSLLIALVVGITAAGEVADRVLDAVVGRLAMRPVSGEVVIVALDERTITQSPSRNFSMTQYANVV
EAVDKAGARRLFIDFYFDRREADHDFPRFVSAVKNMGDRIVLAVSTRQVPGREDKVTTFPSKKFGPDVPIASIAVESEFW
QVWRVPIAYRAEGKLLPTFASIMAGKSSDTPKSFRLDLSYDTRTITEYSAADLLSGKIGARELAGKDVIFAPTAPSFQDY
FYLPGHDRVPGGFIHVIAAETLKRGDPIDIGWLPPLLVAIALTGITLLRRFQRAVLPAIIGTIVILIGGKIVLGTMLVTS
WIGAALVYVAAIATNVSRTRRRSSAQRENPVSGLPNFEALRSLPPFGSATVIAAKVVNFEDLAAFIPGDGIGKLVEQVTR
RLQLASQGTTLHHDLDGTFAWLVPYYQHSQIEGQLAGLAALFNAPLTIGDLRVDVAIAFGVNDEFEGSNAQRLAAALVAA
ERAIRTRALWTKYTPRQKDGAGWQLSFHSQLEDALTGGDIWVAFQPQYEIATRRLVGVEALARWTHPTRGPIPPDEFIIQ
AEKSQDIYRLTLFVMDQAIRSAAELRGRGVHINMSVNLSATLLDHSDLVGTIRVMLTAHHLPPETLTIEITETAQIENSR
QARQTLAQLRRTGIRLSIDDYGTGQSNLEYLTEIEADEIKIDKRFVSTMHDSQRNREVVKSTIDLAHRLGAVAVAEGIED
AETMALLASLGCDVGQGYHLGKPQLFSDLIAALTTPPHSRSA

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=426, Percent_Identity=27.6995305164319, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787541, Length=468, Percent_Identity=27.5641025641026, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=33.0677290836653, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=32.1428571428571, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI226510982, Length=254, Percent_Identity=29.9212598425197, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787055, Length=363, Percent_Identity=25.8953168044077, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=30.379746835443, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=32.421875, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87081980, Length=265, Percent_Identity=29.811320754717, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87082096, Length=246, Percent_Identity=31.3008130081301, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=28.1632653061224, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786507, Length=234, Percent_Identity=31.1965811965812, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=25.764192139738, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83398; Mature: 83266

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPVKSLIISWRSIGLSLLIALVVGITAAGEVADRVLDAVVGRLAMRPVSGEVVIVALD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
ERTITQSPSRNFSMTQYANVVEAVDKAGARRLFIDFYFDRREADHDFPRFVSAVKNMGDR
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCE
IVLAVSTRQVPGREDKVTTFPSKKFGPDVPIASIAVESEFWQVWRVPIAYRAEGKLLPTF
EEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHEEEHHHHHHHHCCCEEEECCCCCHHHH
ASIMAGKSSDTPKSFRLDLSYDTRTITEYSAADLLSGKIGARELAGKDVIFAPTAPSFQD
HHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCC
YFYLPGHDRVPGGFIHVIAAETLKRGDPIDIGWLPPLLVAIALTGITLLRRFQRAVLPAI
EEEECCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTIVILIGGKIVLGTMLVTSWIGAALVYVAAIATNVSRTRRRSSAQRENPVSGLPNFEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LRSLPPFGSATVIAAKVVNFEDLAAFIPGDGIGKLVEQVTRRLQLASQGTTLHHDLDGTF
HHCCCCCCCCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCE
AWLVPYYQHSQIEGQLAGLAALFNAPLTIGDLRVDVAIAFGVNDEFEGSNAQRLAAALVA
EEEEHHHHCCCCHHHHHHHHHHHCCCCEEECEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AERAIRTRALWTKYTPRQKDGAGWQLSFHSQLEDALTGGDIWVAFQPQYEIATRRLVGVE
HHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ALARWTHPTRGPIPPDEFIIQAEKSQDIYRLTLFVMDQAIRSAAELRGRGVHINMSVNLS
HHHHCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
ATLLDHSDLVGTIRVMLTAHHLPPETLTIEITETAQIENSRQARQTLAQLRRTGIRLSID
EEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHCCCEEEEC
DYGTGQSNLEYLTEIEADEIKIDKRFVSTMHDSQRNREVVKSTIDLAHRLGAVAVAEGIE
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAETMALLASLGCDVGQGYHLGKPQLFSDLIAALTTPPHSRSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PIPVKSLIISWRSIGLSLLIALVVGITAAGEVADRVLDAVVGRLAMRPVSGEVVIVALD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
ERTITQSPSRNFSMTQYANVVEAVDKAGARRLFIDFYFDRREADHDFPRFVSAVKNMGDR
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCE
IVLAVSTRQVPGREDKVTTFPSKKFGPDVPIASIAVESEFWQVWRVPIAYRAEGKLLPTF
EEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHEEEHHHHHHHHCCCEEEECCCCCHHHH
ASIMAGKSSDTPKSFRLDLSYDTRTITEYSAADLLSGKIGARELAGKDVIFAPTAPSFQD
HHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCC
YFYLPGHDRVPGGFIHVIAAETLKRGDPIDIGWLPPLLVAIALTGITLLRRFQRAVLPAI
EEEECCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTIVILIGGKIVLGTMLVTSWIGAALVYVAAIATNVSRTRRRSSAQRENPVSGLPNFEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LRSLPPFGSATVIAAKVVNFEDLAAFIPGDGIGKLVEQVTRRLQLASQGTTLHHDLDGTF
HHCCCCCCCCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCE
AWLVPYYQHSQIEGQLAGLAALFNAPLTIGDLRVDVAIAFGVNDEFEGSNAQRLAAALVA
EEEEHHHHCCCCHHHHHHHHHHHCCCCEEECEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AERAIRTRALWTKYTPRQKDGAGWQLSFHSQLEDALTGGDIWVAFQPQYEIATRRLVGVE
HHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ALARWTHPTRGPIPPDEFIIQAEKSQDIYRLTLFVMDQAIRSAAELRGRGVHINMSVNLS
HHHHCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
ATLLDHSDLVGTIRVMLTAHHLPPETLTIEITETAQIENSRQARQTLAQLRRTGIRLSID
EEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHCCCEEEEC
DYGTGQSNLEYLTEIEADEIKIDKRFVSTMHDSQRNREVVKSTIDLAHRLGAVAVAEGIE
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAETMALLASLGCDVGQGYHLGKPQLFSDLIAALTTPPHSRSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]