| Definition | Sphingopyxis alaskensis RB2256, complete genome. |
|---|---|
| Accession | NC_008048 |
| Length | 3,345,170 |
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The map label for this gene is nrdA [H]
Identifier: 103487258
GI number: 103487258
Start: 1870880
End: 1872910
Strand: Direct
Name: nrdA [H]
Synonym: Sala_1773
Alternate gene names: 103487258
Gene position: 1870880-1872910 (Clockwise)
Preceding gene: 103487256
Following gene: 103487259
Centisome position: 55.93
GC content: 64.01
Gene sequence:
>2031_bases ATGCTAAGACCGGGGCTTCGCCCTGAGTCGAACAAGACAGGAACATGTGCGCGCTTGCGCGCATTCAGATCGGGGGCGAA CAGGATGGATTTTCGGGACAGCGAACGGGTGGAGACGAACGACGTGGCGACGGTGGAACTGACGAAAATTGATGCTCCAG CAGCGCCGGAGGCAAAGGGCGAATCGACGCCCGCGTCCGCCGCGAAGCCGGGCGACGGCGGCGAACCCAAGGTCCACGCG CGCCGATTCGCCATCGTGACCGATGCGAGCCGCGATGCGCTGCTTACCGATTTCGGCAAGGAAACGCTGCAGGACCGCTA CCTCCTCCCCGGCGAATCCTATCAGGATCTCTTCGCGCGCGTCGCCGACGCCTATGCCGACGATCAGGATCATGCCCAGC GGCTCTACGACTATATCTCGAAGCTGTGGTTCATGCCCGCGACCCCCGTGCTCTCGAACGGCGGCACCGGCCGCGGCCTG CCGATCAGCTGCTACCTCAATTCGGTTGACGACAGCCTCGAGGGGATCGTCGGCACGTGGAACGAGAATGTCTGGCTCGC CAGCCGCGGCGGCGGCATCGGCACCTATTGGGGCGCGGTGCGCGGCATCGGCGAACCCGTGGGCCTCAACGGCAAGACGA GCGGCATCATCCCCTTCGTCCGCGTGATGGATTCGCTCACCCTCGCGATTTCGCAAGGCTCGCTCCGCCGCGGCTCGGCC GCCTGCTATCTCGACATCTCGCATCCCGAAATCGAGGAGTTTCTGGAGATTCGCAAGCCGTCGGGCGACTTCAACCGCAA GGCGCTCAACCTCCACCACGGCGTGCTCATCACCGACGAGTTCATGGAGGCCGTTCGCGACGGCACCGAATTCAACCTCC GCTCACCGAAGGACAACAGCGTCCGCGGCACCGTCGACGCGCGCTCGCTCTTCCAGAAGCTCGTCGAAACGCGCCTCGCG ACCGGCGAGCCCTATATCATCTTCATCGACCAGGTGAACCGCATGATGCCCAAGCATCACCGCGACCTGGGGCTCAAGGT CACCACCTCGAACCTCTGCTCCGAAATCACCCTGCCCACCGGCCGCGACCATCTCGGCAACGATCGCACCGCGGTCTGCT GCCTCTCGAGCCTCAACCTCGAAACCTGGGACGAGTGGAACGGCGACAAGCGCTTCATCGAAGATGTGATGCGGATGCTC GACAATGTCCTTCAGGACTATATCGACCGCGCCCCGCCCGAAATGGCGCGCGCCAAATATAGCGCCAGCCGCGAACGCTC GGTCGGCCTCGGCGTCATGGGCTTCCACAGCTTCCTGCAGGCGCGCGGCCTGCCGTTCGAGGGGGCGATGGCGAAATCGT CGAACCTGCGCATCTTCAAGCATATCCGCGCGCAGGTCGATCAGGCATCGATGCTGCTCGCCAAGGAACGCGGCCCCTGC CCCGACGCCGCCGATCAGGGGGTGATGGAACGCTTTTCCTGCAAGATGGCGATCGCGCCGACCGCGTCGATCAGCATCAT CTGCGGCGGCACCAGCGCGTGTATCGAGCCGATCCCGGCGAACATCTACACGCACAAGACGCTCTCGGGCAGCTTCTCGA TCCGCAACCCGCACCTCGAGGCGCTGCTCGTCGACAAGGCGAAGAACAGCGACGCGGTGTGGAACTCGATCCTCGAGCGC GGGGGCAGCGTCCAGCACCTCGACTTCCTGACGCAGGACGAAAAGGATGTGTTCAAGACCAGCTTCGAGATCGACCAGCG CTGGCTGCTCGAACTCGCCGCCGACCGCACGCCCTATATCGACCAGGCGGCATCGCTGAACCTGTTCATCCCGGCCGACG TCGAGAAATGGGATCTGCTCATGCTCCACTATCGCGCGTGGGAACTCGGCATCAAATCGCTCTATTATCTCCGCTCGAAA TCGGTGCAGCGCGCCGGCTTCGCGGGCGGGGTCGAGGCCGACAACACGCCCGAGGCCGCGAAATTCGAACTCGCGACCAC CGATTACGACGAGTGTCTGGCTTGTCAGTGA
Upstream 100 bases:
>100_bases AGTGTCAGGCTGGAAGTGGCGGATTTCCGTCGCCCATCGCATATGGGCCCGGAAAAACCCTGCTTGCGCCCAAAAAAGGT GCCCACGCCGAGGGGTAAAG
Downstream 100 bases:
>100_bases GTGGTCCCTCTCCCACCGGGAGAGGGAGGGAGGCGCGAAGCGCCGGAAGGGAGGGGGTGACGACCCCGATGCGGACCTAT CGCAATCAACCCGCCGGCAC
Product: ribonucleotide-diphosphate reductase subunit alpha
Products: NA
Alternate protein names: Ribonucleotide reductase [H]
Number of amino acids: Translated: 676; Mature: 676
Protein sequence:
>676_residues MLRPGLRPESNKTGTCARLRAFRSGANRMDFRDSERVETNDVATVELTKIDAPAAPEAKGESTPASAAKPGDGGEPKVHA RRFAIVTDASRDALLTDFGKETLQDRYLLPGESYQDLFARVADAYADDQDHAQRLYDYISKLWFMPATPVLSNGGTGRGL PISCYLNSVDDSLEGIVGTWNENVWLASRGGGIGTYWGAVRGIGEPVGLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSA ACYLDISHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDEFMEAVRDGTEFNLRSPKDNSVRGTVDARSLFQKLVETRLA TGEPYIIFIDQVNRMMPKHHRDLGLKVTTSNLCSEITLPTGRDHLGNDRTAVCCLSSLNLETWDEWNGDKRFIEDVMRML DNVLQDYIDRAPPEMARAKYSASRERSVGLGVMGFHSFLQARGLPFEGAMAKSSNLRIFKHIRAQVDQASMLLAKERGPC PDAADQGVMERFSCKMAIAPTASISIICGGTSACIEPIPANIYTHKTLSGSFSIRNPHLEALLVDKAKNSDAVWNSILER GGSVQHLDFLTQDEKDVFKTSFEIDQRWLLELAADRTPYIDQAASLNLFIPADVEKWDLLMLHYRAWELGIKSLYYLRSK SVQRAGFAGGVEADNTPEAAKFELATTDYDECLACQ
Sequences:
>Translated_676_residues MLRPGLRPESNKTGTCARLRAFRSGANRMDFRDSERVETNDVATVELTKIDAPAAPEAKGESTPASAAKPGDGGEPKVHA RRFAIVTDASRDALLTDFGKETLQDRYLLPGESYQDLFARVADAYADDQDHAQRLYDYISKLWFMPATPVLSNGGTGRGL PISCYLNSVDDSLEGIVGTWNENVWLASRGGGIGTYWGAVRGIGEPVGLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSA ACYLDISHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDEFMEAVRDGTEFNLRSPKDNSVRGTVDARSLFQKLVETRLA TGEPYIIFIDQVNRMMPKHHRDLGLKVTTSNLCSEITLPTGRDHLGNDRTAVCCLSSLNLETWDEWNGDKRFIEDVMRML DNVLQDYIDRAPPEMARAKYSASRERSVGLGVMGFHSFLQARGLPFEGAMAKSSNLRIFKHIRAQVDQASMLLAKERGPC PDAADQGVMERFSCKMAIAPTASISIICGGTSACIEPIPANIYTHKTLSGSFSIRNPHLEALLVDKAKNSDAVWNSILER GGSVQHLDFLTQDEKDVFKTSFEIDQRWLLELAADRTPYIDQAASLNLFIPADVEKWDLLMLHYRAWELGIKSLYYLRSK SVQRAGFAGGVEADNTPEAAKFELATTDYDECLACQ >Mature_676_residues MLRPGLRPESNKTGTCARLRAFRSGANRMDFRDSERVETNDVATVELTKIDAPAAPEAKGESTPASAAKPGDGGEPKVHA RRFAIVTDASRDALLTDFGKETLQDRYLLPGESYQDLFARVADAYADDQDHAQRLYDYISKLWFMPATPVLSNGGTGRGL PISCYLNSVDDSLEGIVGTWNENVWLASRGGGIGTYWGAVRGIGEPVGLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSA ACYLDISHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDEFMEAVRDGTEFNLRSPKDNSVRGTVDARSLFQKLVETRLA TGEPYIIFIDQVNRMMPKHHRDLGLKVTTSNLCSEITLPTGRDHLGNDRTAVCCLSSLNLETWDEWNGDKRFIEDVMRML DNVLQDYIDRAPPEMARAKYSASRERSVGLGVMGFHSFLQARGLPFEGAMAKSSNLRIFKHIRAQVDQASMLLAKERGPC PDAADQGVMERFSCKMAIAPTASISIICGGTSACIEPIPANIYTHKTLSGSFSIRNPHLEALLVDKAKNSDAVWNSILER GGSVQHLDFLTQDEKDVFKTSFEIDQRWLLELAADRTPYIDQAASLNLFIPADVEKWDLLMLHYRAWELGIKSLYYLRSK SVQRAGFAGGVEADNTPEAAKFELATTDYDECLACQ
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 3 ATP-cone domains [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=621, Percent_Identity=32.0450885668277, Blast_Score=271, Evalue=2e-72, Organism=Escherichia coli, GI1789030, Length=595, Percent_Identity=27.0588235294118, Blast_Score=164, Evalue=2e-41, Organism=Escherichia coli, GI2367133, Length=619, Percent_Identity=25.2019386106624, Blast_Score=137, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17555242, Length=661, Percent_Identity=31.4674735249622, Blast_Score=265, Evalue=5e-71, Organism=Saccharomyces cerevisiae, GI6320914, Length=630, Percent_Identity=31.5873015873016, Blast_Score=268, Evalue=2e-72, Organism=Saccharomyces cerevisiae, GI6322123, Length=630, Percent_Identity=30.7936507936508, Blast_Score=261, Evalue=3e-70, Organism=Drosophila melanogaster, GI17352481, Length=633, Percent_Identity=29.3838862559242, Blast_Score=243, Evalue=5e-64,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005144 - InterPro: IPR013346 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 [H]
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 74776; Mature: 74776
Theoretical pI: Translated: 5.69; Mature: 5.69
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLRPGLRPESNKTGTCARLRAFRSGANRMDFRDSERVETNDVATVELTKIDAPAAPEAKG CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC ESTPASAAKPGDGGEPKVHARRFAIVTDASRDALLTDFGKETLQDRYLLPGESYQDLFAR CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCHHHHHCCCCCCCCCHHHHHHH VADAYADDQDHAQRLYDYISKLWFMPATPVLSNGGTGRGLPISCYLNSVDDSLEGIVGTW HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCHHHHCEEECC NENVWLASRGGGIGTYWGAVRGIGEPVGLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSA CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCE ACYLDISHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDEFMEAVRDGTEFNLRSPKDNS EEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCEEEEHHHHHHHHCCCCEECCCCCCCC VRGTVDARSLFQKLVETRLATGEPYIIFIDQVNRMMPKHHRDLGLKVTTSNLCSEITLPT CEECHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHHCCCCEEEHHHHHHHCCCCC GRDHLGNDRTAVCCLSSLNLETWDEWNGDKRFIEDVMRMLDNVLQDYIDRAPPEMARAKY CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH SASRERSVGLGVMGFHSFLQARGLPFEGAMAKSSNLRIFKHIRAQVDQASMLLAKERGPC HCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC PDAADQGVMERFSCKMAIAPTASISIICGGTSACIEPIPANIYTHKTLSGSFSIRNPHLE CCHHHHHHHHHHCCCEEECCCCEEEEEECCCHHHCCCCCCCEEEEEECCCCEEECCCCEE ALLVDKAKNSDAVWNSILERGGSVQHLDFLTQDEKDVFKTSFEIDQRWLLELAADRTPYI EEEEECCCCCHHHHHHHHHCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC DQAASLNLFIPADVEKWDLLMLHYRAWELGIKSLYYLRSKSVQRAGFAGGVEADNTPEAA CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCC KFELATTDYDECLACQ EEEEECCCHHHHHCCC >Mature Secondary Structure MLRPGLRPESNKTGTCARLRAFRSGANRMDFRDSERVETNDVATVELTKIDAPAAPEAKG CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC ESTPASAAKPGDGGEPKVHARRFAIVTDASRDALLTDFGKETLQDRYLLPGESYQDLFAR CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCHHHHHCCCCCCCCCHHHHHHH VADAYADDQDHAQRLYDYISKLWFMPATPVLSNGGTGRGLPISCYLNSVDDSLEGIVGTW HHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCHHHHCEEECC NENVWLASRGGGIGTYWGAVRGIGEPVGLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSA CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCE ACYLDISHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDEFMEAVRDGTEFNLRSPKDNS EEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCEEEEHHHHHHHHCCCCEECCCCCCCC VRGTVDARSLFQKLVETRLATGEPYIIFIDQVNRMMPKHHRDLGLKVTTSNLCSEITLPT CEECHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHHCCCCEEEHHHHHHHCCCCC GRDHLGNDRTAVCCLSSLNLETWDEWNGDKRFIEDVMRMLDNVLQDYIDRAPPEMARAKY CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH SASRERSVGLGVMGFHSFLQARGLPFEGAMAKSSNLRIFKHIRAQVDQASMLLAKERGPC HCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC PDAADQGVMERFSCKMAIAPTASISIICGGTSACIEPIPANIYTHKTLSGSFSIRNPHLE CCHHHHHHHHHHCCCEEECCCCEEEEEECCCHHHCCCCCCCEEEEEECCCCEEECCCCEE ALLVDKAKNSDAVWNSILERGGSVQHLDFLTQDEKDVFKTSFEIDQRWLLELAADRTPYI EEEEECCCCCHHHHHHHHHCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC DQAASLNLFIPADVEKWDLLMLHYRAWELGIKSLYYLRSKSVQRAGFAGGVEADNTPEAA CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCC KFELATTDYDECLACQ EEEEECCCHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10684935 [H]