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The map label for this gene is moaA [H]

Identifier: 103487140

GI number: 103487140

Start: 1740492

End: 1741505

Strand: Direct

Name: moaA [H]

Synonym: Sala_1655

Alternate gene names: 103487140

Gene position: 1740492-1741505 (Clockwise)

Preceding gene: 103487138

Following gene: 103487141

Centisome position: 52.03

GC content: 68.84

Gene sequence:

>1014_bases
ATGGTCACATTATCCCAGCCTGCCGCCCCGGCGGCGCCGCTGATCGACGGCCATGGCCGCCGGATCAGTTACTTGCGCCT
GTCGGTGACCGACCGCTGCGACCTGCGGTGCCGCTACTGCATGGCCGAAGACATGCGGTTCCTGCCGAAATCGGCGGTGC
TCAGCATCGAGGAAATGGCCGAGCTGGCGGAGCGATTCGTTGCGCGCGGCGTTCGCCGCATCCGCCTGACCGGCGGCGAA
CCGCTGGTGCGGCGCGGCATCGACACGCTGGCGACGCGGCTCGGCGCTCTGATCGGCCGCGGCCTCGACGAGCTGACGCT
GACCACCAACGCCATGCGACTGGCGGACCACGCACCGATGCTCGCCGCGGCGGGCGTGCGGCGCATCAATATCAGCCTCG
ATACGCTCGACCCGGCTGCATTCCGCCACATCACCCGCGTCGGCGACCTCGACGTCGCGCTCGCCGGGATCGCCGCGGCG
CGGCTGGCCGGGCTGGCGGTCAAGATCAACATGGTGGCGCTCGCCGGGCTGAACGAGGATCAGCTGCTGCCGATGCTGCG
CTGGTGCGCCGACAATGGCTGCGACCTCACGCTCATCGAAACCATGCCGCTCGGCGAGGTCGAGGATGACCGCAGCGATC
ATTATATCCCGCTGCACCAGTTCATCGCCCCGCTGCGCGCCGCGCACGCGCTTTATCCGGTGGACAAGCGCACCGGCGGC
CCGGCGCGCTATTTCGCGGTCGAGGGCAGCCCGGTCACCCTGGGCCTCATCACCCCGCTCAGCGACAATTTCTGCGCGAC
GTGCAACCGCATCCGGCTGACGGTGGAGGGGCGCGTCTATATGTGCCTTGGTCAGGACGATCATGTCGACCTGCGCGCGG
CACTGCGCGGCGGCGGCGATGTCGACAGCTTGATCGACCGGGCGCTGGCTGGCAAACCCCGCGCGCACGACTTTCATATC
GAACGGCAATCCAGACCGGCGGTCGCACGCCACATGAGCGCAACGGGCGGCTGA

Upstream 100 bases:

>100_bases
CGGGCGCAGGCGGTCAGGGATTCGGACAAGCGATTCATTGGCGCTGCCTAGCAGGCTTTGCTTGCCAAACGCTTGCCTTT
TGCATCACAAGACGCACGTG

Downstream 100 bases:

>100_bases
CGGGCCGCTTGCGGAGGGGGAACCGGACCAGATGTTTCGCAAGATCGCGCTTGTCGCGTCAAGTGCGCCCGCGGCCATCG
AGGCCGAAGCCGAGTTGCGG

Product: molybdenum cofactor synthesis-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVTLSQPAAPAAPLIDGHGRRISYLRLSVTDRCDLRCRYCMAEDMRFLPKSAVLSIEEMAELAERFVARGVRRIRLTGGE
PLVRRGIDTLATRLGALIGRGLDELTLTTNAMRLADHAPMLAAAGVRRINISLDTLDPAAFRHITRVGDLDVALAGIAAA
RLAGLAVKINMVALAGLNEDQLLPMLRWCADNGCDLTLIETMPLGEVEDDRSDHYIPLHQFIAPLRAAHALYPVDKRTGG
PARYFAVEGSPVTLGLITPLSDNFCATCNRIRLTVEGRVYMCLGQDDHVDLRAALRGGGDVDSLIDRALAGKPRAHDFHI
ERQSRPAVARHMSATGG

Sequences:

>Translated_337_residues
MVTLSQPAAPAAPLIDGHGRRISYLRLSVTDRCDLRCRYCMAEDMRFLPKSAVLSIEEMAELAERFVARGVRRIRLTGGE
PLVRRGIDTLATRLGALIGRGLDELTLTTNAMRLADHAPMLAAAGVRRINISLDTLDPAAFRHITRVGDLDVALAGIAAA
RLAGLAVKINMVALAGLNEDQLLPMLRWCADNGCDLTLIETMPLGEVEDDRSDHYIPLHQFIAPLRAAHALYPVDKRTGG
PARYFAVEGSPVTLGLITPLSDNFCATCNRIRLTVEGRVYMCLGQDDHVDLRAALRGGGDVDSLIDRALAGKPRAHDFHI
ERQSRPAVARHMSATGG
>Mature_337_residues
MVTLSQPAAPAAPLIDGHGRRISYLRLSVTDRCDLRCRYCMAEDMRFLPKSAVLSIEEMAELAERFVARGVRRIRLTGGE
PLVRRGIDTLATRLGALIGRGLDELTLTTNAMRLADHAPMLAAAGVRRINISLDTLDPAAFRHITRVGDLDVALAGIAAA
RLAGLAVKINMVALAGLNEDQLLPMLRWCADNGCDLTLIETMPLGEVEDDRSDHYIPLHQFIAPLRAAHALYPVDKRTGG
PARYFAVEGSPVTLGLITPLSDNFCATCNRIRLTVEGRVYMCLGQDDHVDLRAALRGGGDVDSLIDRALAGKPRAHDFHI
ERQSRPAVARHMSATGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI22027536, Length=338, Percent_Identity=37.2781065088757, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI116734668, Length=338, Percent_Identity=37.2781065088757, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1786999, Length=333, Percent_Identity=31.5315315315315, Blast_Score=165, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=331, Percent_Identity=32.9305135951662, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI32566329, Length=310, Percent_Identity=33.2258064516129, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17561210, Length=310, Percent_Identity=33.5483870967742, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28574488, Length=327, Percent_Identity=36.085626911315, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI28574490, Length=327, Percent_Identity=36.085626911315, Blast_Score=178, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 36624; Mature: 36624

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01305 MOAA_NIFB_PQQE ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLSQPAAPAAPLIDGHGRRISYLRLSVTDRCDLRCRYCMAEDMRFLPKSAVLSIEEMA
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHCCHHHHEEHHHHH
ELAERFVARGVRRIRLTGGEPLVRRGIDTLATRLGALIGRGLDELTLTTNAMRLADHAPM
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHCCCH
LAAAGVRRINISLDTLDPAAFRHITRVGDLDVALAGIAAARLAGLAVKINMVALAGLNED
HHHCCEEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCHH
QLLPMLRWCADNGCDLTLIETMPLGEVEDDRSDHYIPLHQFIAPLRAAHALYPVDKRTGG
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCC
PARYFAVEGSPVTLGLITPLSDNFCATCNRIRLTVEGRVYMCLGQDDHVDLRAALRGGGD
CEEEEEECCCCEEEEEECCCCCCHHCCCEEEEEEECCEEEEEECCCCCCCHHHHHCCCCC
VDSLIDRALAGKPRAHDFHIERQSRPAVARHMSATGG
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCC
>Mature Secondary Structure
MVTLSQPAAPAAPLIDGHGRRISYLRLSVTDRCDLRCRYCMAEDMRFLPKSAVLSIEEMA
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHCCHHHHEEHHHHH
ELAERFVARGVRRIRLTGGEPLVRRGIDTLATRLGALIGRGLDELTLTTNAMRLADHAPM
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHCCCH
LAAAGVRRINISLDTLDPAAFRHITRVGDLDVALAGIAAARLAGLAVKINMVALAGLNED
HHHCCEEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCHH
QLLPMLRWCADNGCDLTLIETMPLGEVEDDRSDHYIPLHQFIAPLRAAHALYPVDKRTGG
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCC
PARYFAVEGSPVTLGLITPLSDNFCATCNRIRLTVEGRVYMCLGQDDHVDLRAALRGGGD
CEEEEEECCCCEEEEEECCCCCCHHCCCEEEEEEECCEEEEEECCCCCCCHHHHHCCCCC
VDSLIDRALAGKPRAHDFHIERQSRPAVARHMSATGG
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA