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The map label for this gene is pheA [H]

Identifier: 103486115

GI number: 103486115

Start: 633209

End: 634102

Strand: Direct

Name: pheA [H]

Synonym: Sala_0622

Alternate gene names: 103486115

Gene position: 633209-634102 (Clockwise)

Preceding gene: 103486112

Following gene: 103486121

Centisome position: 18.93

GC content: 66.0

Gene sequence:

>894_bases
ATGGGCAGTTATTCGGCTTCGGCGCAGCATCTGGTCGACAAAATGCGGGCGCTGGCCCTGGCCGAACCCGCGCGCGGGCT
GGCGTTCCAGGGCGCGCCTGGCGCGAACAGCGACCTCGCCGCGCGCGAATATGACCCGAACTCGCTGCCGCTGCCCTGCT
ATGCCTTCGAGGATGCGATCGATGCGGTGCGCGAAGGCCTGGTCGACCGCGCGATCATTCCGATCGAGAACAGCCTGCAT
GGCCGGGTCGCCGACATTCATTTCCTGCTCCCCGAATCCGGCCTGTCGATTGTCGGCGAACATTTCCTGCCGATCCGCTA
TGGGTTGATGAGCCGCAATCTGGGACCGGTGACGCGCGCGATGAGCCACGAACAGGCGCTCGGCCAGTGCCGCAAATGGT
TGCGCGCCAATAATATCGCGCCCGTCGCGCACAGCGACACCGCGGGCGCCGCCGCCTGGGTTGCCGACAGCGACGAGGTC
GGGCTCGCCGCACTGGCGCCGCCGCACGCCGCCGACCTCTATGGCCTGACGCTGCACGGCACGGGAATGGAGGACGCCGA
TCATAATATGACGCGCTTCGTCGTGCTCGCGCGCGAGCCCTTGCGCGATCTTTCGGCAGTCGAAGGGCCGGTGATGACGA
CCTTCATGTTCGAGGTGAAGAATATCCCCGCTGCGCTCTACAAGGCGCTCGGCGGCTTTGCGACCAACGGCGTCAACATG
ACCAAGCTCGAAAGCTATCAGACGGGCGGCAGCTTTGCCGCGACCAAATTTTACGCCGACATCGTCGGCGCGCCGGGCGA
CGAACGTGTCGACCGCGCGCTGGAGGAGCTGGATTTCCAGACCAAGTCGCTGCGCCTGCTCGGCACTTATCCGCAGGCGC
GCCCGCGTCCCTGA

Upstream 100 bases:

>100_bases
GCGCAAGGGGATGAAATCGGCGGACGGGTCGCCGCCGCGGCTGGTTGCGCGCTGGCGGCGGTGTCGCTATGCGCCGCGGT
TCCAGCGTGGGAAGGCAGTC

Downstream 100 bases:

>100_bases
GCCTTTCAGTTGCCGCGGCGGCGCAGCATCCGCGCGGTCATCGACGTCTGGACGACAAACAGCGTGACGAGGATGCTCGC
GACGACGAGCGCGAACAGGT

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGSYSASAQHLVDKMRALALAEPARGLAFQGAPGANSDLAAREYDPNSLPLPCYAFEDAIDAVREGLVDRAIIPIENSLH
GRVADIHFLLPESGLSIVGEHFLPIRYGLMSRNLGPVTRAMSHEQALGQCRKWLRANNIAPVAHSDTAGAAAWVADSDEV
GLAALAPPHAADLYGLTLHGTGMEDADHNMTRFVVLAREPLRDLSAVEGPVMTTFMFEVKNIPAALYKALGGFATNGVNM
TKLESYQTGGSFAATKFYADIVGAPGDERVDRALEELDFQTKSLRLLGTYPQARPRP

Sequences:

>Translated_297_residues
MGSYSASAQHLVDKMRALALAEPARGLAFQGAPGANSDLAAREYDPNSLPLPCYAFEDAIDAVREGLVDRAIIPIENSLH
GRVADIHFLLPESGLSIVGEHFLPIRYGLMSRNLGPVTRAMSHEQALGQCRKWLRANNIAPVAHSDTAGAAAWVADSDEV
GLAALAPPHAADLYGLTLHGTGMEDADHNMTRFVVLAREPLRDLSAVEGPVMTTFMFEVKNIPAALYKALGGFATNGVNM
TKLESYQTGGSFAATKFYADIVGAPGDERVDRALEELDFQTKSLRLLGTYPQARPRP
>Mature_296_residues
GSYSASAQHLVDKMRALALAEPARGLAFQGAPGANSDLAAREYDPNSLPLPCYAFEDAIDAVREGLVDRAIIPIENSLHG
RVADIHFLLPESGLSIVGEHFLPIRYGLMSRNLGPVTRAMSHEQALGQCRKWLRANNIAPVAHSDTAGAAAWVADSDEVG
LAALAPPHAADLYGLTLHGTGMEDADHNMTRFVVLAREPLRDLSAVEGPVMTTFMFEVKNIPAALYKALGGFATNGVNMT
KLESYQTGGSFAATKFYADIVGAPGDERVDRALEELDFQTKSLRLLGTYPQARPRP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=279, Percent_Identity=32.6164874551971, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31927; Mature: 31795

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSYSASAQHLVDKMRALALAEPARGLAFQGAPGANSDLAAREYDPNSLPLPCYAFEDAI
CCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DAVREGLVDRAIIPIENSLHGRVADIHFLLPESGLSIVGEHFLPIRYGLMSRNLGPVTRA
HHHHHHHHHCEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
MSHEQALGQCRKWLRANNIAPVAHSDTAGAAAWVADSDEVGLAALAPPHAADLYGLTLHG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEEEC
TGMEDADHNMTRFVVLAREPLRDLSAVEGPVMTTFMFEVKNIPAALYKALGGFATNGVNM
CCCCCCCCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCHHCCCCCH
TKLESYQTGGSFAATKFYADIVGAPGDERVDRALEELDFQTKSLRLLGTYPQARPRP
HEEHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCC
>Mature Secondary Structure 
GSYSASAQHLVDKMRALALAEPARGLAFQGAPGANSDLAAREYDPNSLPLPCYAFEDAI
CCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DAVREGLVDRAIIPIENSLHGRVADIHFLLPESGLSIVGEHFLPIRYGLMSRNLGPVTRA
HHHHHHHHHCEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
MSHEQALGQCRKWLRANNIAPVAHSDTAGAAAWVADSDEVGLAALAPPHAADLYGLTLHG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEEEC
TGMEDADHNMTRFVVLAREPLRDLSAVEGPVMTTFMFEVKNIPAALYKALGGFATNGVNM
CCCCCCCCCCEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCHHCCCCCH
TKLESYQTGGSFAATKFYADIVGAPGDERVDRALEELDFQTKSLRLLGTYPQARPRP
HEEHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]