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The map label for this gene is exuT [H]

Identifier: 103486001

GI number: 103486001

Start: 525790

End: 527106

Strand: Direct

Name: exuT [H]

Synonym: Sala_0508

Alternate gene names: 103486001

Gene position: 525790-527106 (Clockwise)

Preceding gene: 103486000

Following gene: 103486004

Centisome position: 15.72

GC content: 66.36

Gene sequence:

>1317_bases
ATGAACGAAAAACCTGCGCTTGCCGCGGGGCTTGGGTCGGCCCCCGTCGACAGCGCCGCCGCACAGACGCGGACGATGCT
GTGGATCCTGCTCATCGTCTATATCTTCAATTTCCTCGACCGGCAGATCGTCAACATCCTCGCCGAACCGATCAAGGCCG
ACCTTGGGCTCTCCGATACCGAACTGGGCCTGCTCGCGGGCCCGGCCTTTGCGGTCTTCTATGCGCTGCTCGGCATTCCC
ATCGCGCGCTATGCCGACAAGGACGGCACCAACCGCGTCCGGCTGATCGCCGCCGCGCTCGCCATCTGGTCGGCGATGAC
CGCGGTGTGCGGCCTCGCGCAAAACTTCGTGCAATTGCTGCTCGCGCGCATCGGCGTCGGCGTCGGCGAGGCGGGTTGCA
CGCCCGCCGCCCACTCGCTCATCACCGACAGCGTGCCGCCGGAAAAGCGTTCGTCGGCCATCGCCTTTTACGGCATGGGC
GTGCCGATCGGATCGCTGCTCGGGCTGATCATCGGCGGCATCGTCAACGACCTCTACGGCTGGCGCATCGCGCTGATGCT
CGTCGGGGCGCCGGGCCTGCTCCTCGCGCTGATCGTGCTCTTCGTGATGCGCGAGCCGCGCCATCGCCGCACCGCCGAAG
CCGCGGCGAGCGCCGCCGCGGTGGTGCGGCTCTCGACCGGCGAGGCGATGAGGGAAATCTTCACCTCGCGCGCGTTCCTC
TACATCCTGATCGCCGCGTCGGTCACCGCGTTCCTCGGCTATGGCAAGGCGCTGTGGACGATCAGCTATTTCATCCGCAG
CCATGGCCTGTCGACGACCGAGGCAGGGCTGTCGATGGCGGTGGTGCTCGGCCTCGCCGGGGTGTTCGGCACCTGGCTCG
GCGGCAAGATGGCCGATATGTTCGGCAAACGCGACAGGAAGCATATCCTGACCTTCCCCGCCTATGGCATGGCGGTGGCC
GCGCCAATCCTGTTCCTTGGCTATTATATGGAGAACTGGCTGGTCGCGGTCGCGCTGCTCATCGTGCCGACGATCCTCAA
TTCGGCCTATTACGGCCCCGCCTATGGCTGCGTTCAGGGGCTGGTGCGGCCGCAGGCGCGCGCGGTCGCGGCGTCGATCA
TGCTGTTCGGGCAGAATCTGATCGGGCTGGGTTTCGGTCCCTTCCTGTTCGGGGTGCTCTCCGACCTGCTAGCGCCCGCC
TATGGGCAGGAAAGCGTGCGCTATGTCCTCTATGGCGCGGCGTGGCTCGGGTTGATCCCCGCCTTCTTCTTCTGGCGCGC
CAGTCTGCGGCTGAAGGCGGAGCTGAAGTCGGGTTAG

Upstream 100 bases:

>100_bases
GGCAGCCGTAGCGGCAATCGCAAGCGGCGATTTTCATCGCGCCGCAGCGGCATTGACAGCCGCCGCCCCGGTCTTCACCC
TTCGTCTTCGGGAGAGAATG

Downstream 100 bases:

>100_bases
GCACCTCTCGTCATTGCGAGCGCAGCGAAGCAATCTCCAGCCATCGGACGTGCGCGAGACCGATGGCTGGAGATCGCCGC
GTCGCCTCCGGCTCATCGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNEKPALAAGLGSAPVDSAAAQTRTMLWILLIVYIFNFLDRQIVNILAEPIKADLGLSDTELGLLAGPAFAVFYALLGIP
IARYADKDGTNRVRLIAAALAIWSAMTAVCGLAQNFVQLLLARIGVGVGEAGCTPAAHSLITDSVPPEKRSSAIAFYGMG
VPIGSLLGLIIGGIVNDLYGWRIALMLVGAPGLLLALIVLFVMREPRHRRTAEAAASAAAVVRLSTGEAMREIFTSRAFL
YILIAASVTAFLGYGKALWTISYFIRSHGLSTTEAGLSMAVVLGLAGVFGTWLGGKMADMFGKRDRKHILTFPAYGMAVA
APILFLGYYMENWLVAVALLIVPTILNSAYYGPAYGCVQGLVRPQARAVAASIMLFGQNLIGLGFGPFLFGVLSDLLAPA
YGQESVRYVLYGAAWLGLIPAFFFWRASLRLKAELKSG

Sequences:

>Translated_438_residues
MNEKPALAAGLGSAPVDSAAAQTRTMLWILLIVYIFNFLDRQIVNILAEPIKADLGLSDTELGLLAGPAFAVFYALLGIP
IARYADKDGTNRVRLIAAALAIWSAMTAVCGLAQNFVQLLLARIGVGVGEAGCTPAAHSLITDSVPPEKRSSAIAFYGMG
VPIGSLLGLIIGGIVNDLYGWRIALMLVGAPGLLLALIVLFVMREPRHRRTAEAAASAAAVVRLSTGEAMREIFTSRAFL
YILIAASVTAFLGYGKALWTISYFIRSHGLSTTEAGLSMAVVLGLAGVFGTWLGGKMADMFGKRDRKHILTFPAYGMAVA
APILFLGYYMENWLVAVALLIVPTILNSAYYGPAYGCVQGLVRPQARAVAASIMLFGQNLIGLGFGPFLFGVLSDLLAPA
YGQESVRYVLYGAAWLGLIPAFFFWRASLRLKAELKSG
>Mature_438_residues
MNEKPALAAGLGSAPVDSAAAQTRTMLWILLIVYIFNFLDRQIVNILAEPIKADLGLSDTELGLLAGPAFAVFYALLGIP
IARYADKDGTNRVRLIAAALAIWSAMTAVCGLAQNFVQLLLARIGVGVGEAGCTPAAHSLITDSVPPEKRSSAIAFYGMG
VPIGSLLGLIIGGIVNDLYGWRIALMLVGAPGLLLALIVLFVMREPRHRRTAEAAASAAAVVRLSTGEAMREIFTSRAFL
YILIAASVTAFLGYGKALWTISYFIRSHGLSTTEAGLSMAVVLGLAGVFGTWLGGKMADMFGKRDRKHILTFPAYGMAVA
APILFLGYYMENWLVAVALLIVPTILNSAYYGPAYGCVQGLVRPQARAVAASIMLFGQNLIGLGFGPFLFGVLSDLLAPA
YGQESVRYVLYGAAWLGLIPAFFFWRASLRLKAELKSG

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=393, Percent_Identity=26.4631043256997, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI14042968, Length=393, Percent_Identity=26.4631043256997, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI215490100, Length=376, Percent_Identity=26.3297872340426, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI185136021, Length=386, Percent_Identity=23.8341968911917, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367379, Length=289, Percent_Identity=27.681660899654, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789152, Length=355, Percent_Identity=23.0985915492958, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082320, Length=311, Percent_Identity=25.08038585209, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082071, Length=341, Percent_Identity=24.0469208211144, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082404, Length=181, Percent_Identity=29.8342541436464, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557872, Length=393, Percent_Identity=26.4631043256997, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193209775, Length=460, Percent_Identity=25.6521739130435, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17539092, Length=446, Percent_Identity=25.5605381165919, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71992409, Length=399, Percent_Identity=24.5614035087719, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654039, Length=380, Percent_Identity=22.6315789473684, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864456, Length=380, Percent_Identity=22.6315789473684, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640209, Length=212, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654037, Length=381, Percent_Identity=22.5721784776903, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654041, Length=381, Percent_Identity=22.5721784776903, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654044, Length=236, Percent_Identity=24.5762711864407, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46618; Mature: 46618

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKPALAAGLGSAPVDSAAAQTRTMLWILLIVYIFNFLDRQIVNILAEPIKADLGLSDT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ELGLLAGPAFAVFYALLGIPIARYADKDGTNRVRLIAAALAIWSAMTAVCGLAQNFVQLL
CHHHHHCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARIGVGVGEAGCTPAAHSLITDSVPPEKRSSAIAFYGMGVPIGSLLGLIIGGIVNDLYG
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
WRIALMLVGAPGLLLALIVLFVMREPRHRRTAEAAASAAAVVRLSTGEAMREIFTSRAFL
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHH
YILIAASVTAFLGYGKALWTISYFIRSHGLSTTEAGLSMAVVLGLAGVFGTWLGGKMADM
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FGKRDRKHILTFPAYGMAVAAPILFLGYYMENWLVAVALLIVPTILNSAYYGPAYGCVQG
HCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVRPQARAVAASIMLFGQNLIGLGFGPFLFGVLSDLLAPAYGQESVRYVLYGAAWLGLIP
HHCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AFFFWRASLRLKAELKSG
HHHHHHHHHHEEEECCCC
>Mature Secondary Structure
MNEKPALAAGLGSAPVDSAAAQTRTMLWILLIVYIFNFLDRQIVNILAEPIKADLGLSDT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ELGLLAGPAFAVFYALLGIPIARYADKDGTNRVRLIAAALAIWSAMTAVCGLAQNFVQLL
CHHHHHCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARIGVGVGEAGCTPAAHSLITDSVPPEKRSSAIAFYGMGVPIGSLLGLIIGGIVNDLYG
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
WRIALMLVGAPGLLLALIVLFVMREPRHRRTAEAAASAAAVVRLSTGEAMREIFTSRAFL
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHH
YILIAASVTAFLGYGKALWTISYFIRSHGLSTTEAGLSMAVVLGLAGVFGTWLGGKMADM
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FGKRDRKHILTFPAYGMAVAAPILFLGYYMENWLVAVALLIVPTILNSAYYGPAYGCVQG
HCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVRPQARAVAASIMLFGQNLIGLGFGPFLFGVLSDLLAPAYGQESVRYVLYGAAWLGLIP
HHCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AFFFWRASLRLKAELKSG
HHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]