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The map label for this gene is ltaE [H]

Identifier: 103485989

GI number: 103485989

Start: 513849

End: 514859

Strand: Direct

Name: ltaE [H]

Synonym: Sala_0496

Alternate gene names: 103485989

Gene position: 513849-514859 (Clockwise)

Preceding gene: 103485988

Following gene: 103485990

Centisome position: 15.36

GC content: 66.96

Gene sequence:

>1011_bases
ATGACCGCGACCCGTTTCTTTTCGGACAATGCCGCTGCGGTCCACCCCGCCGTGATGGAGGCGCTCGTCGCCGCCAACCA
TGTCGATACAGCCTATGACGGCGACGCGCTCAGCCAGTCGCTCGACGCGGCCTTTTCGGACCTGTTCGAAACCGACTGCG
AAGTCGTCTGGGTATCGACCGGGACCGCGGCGAACAGCATCATCCTCGCGCATTTCGTCCGGCCGTGGCAGGGAATCCTC
TGTTACGAGGAAGCGCATATCGAGGTTGACGAATGCGGCGCGCCGACCTTTTATTCGGGCGGCGCCACGCTGATGCCGCT
CCCCGGCCGCGGCGCCAAGATCGACACCGCGGCGCTGAAGGCGCGAATCGCGGGTATCCGGCAGGATGTCCACCAGGTTC
AGCCCGCGGCGGTCAGCATCACCAACGCGACCGAATATGGCCTCGCGTGGCGGCCGCAGGAAATTGGCGAGATCAGCGAG
ATTGCCAGGCGCAAGGGGCTGAAACTCCACATGGACGGCGCGCGCTTCGCCAACGCCGTCGCTTTCCTCGGCTGCGCGCC
CGCCGACGTGACCTGGCGCGCCGGGGTCGATGCGCTGTCGTTCGGTTTCACGAAGAATGGCGCGATGATGGCCGAAGCGA
TCGTCTTTTTCGGCGGCAGCGGCGGCGCGGGGGTGCGCGAGCTCAAGAAGCGCGGCGGGCACCTGCTCAGCAAGGGGCGC
TTCGTCGCGGCACAGATTCGCGCGATGCTGAAGGACGACCTCTGGCTCGCCAATGCGCGCGCCGCCAATGCGGGCGCCGC
GAAACTCGCGGCGGCGTGCGGTAGCCGCCTCCTGTATCCGGTCGAGGCGAACGAGCTTTTCGTGCGGTTGTCCAATGACG
AGGCGGCGAAACTGCGCGGTGCGGGGTTCGATTTTTACGACTGGGGTGAGGGTGCGGCGCGGCTCGTCGTCAGCTGGGAT
CAGGATGCCGAAGCGGTGGCGCCGCTCGCCGCCGCGATCGGTGCGCTATGA

Upstream 100 bases:

>100_bases
GATGCCGGCGCCTATGACCAGAAGGACGCGGCCGGCTTCATCAGGCTCAACGCGCTGCGGCTCAAACTGCTTGCCCGACA
GGGGCGCTGAGGCGCGCGAC

Downstream 100 bases:

>100_bases
GCGCCGCGCCGACGACGCTGCTCAGCCCGCGCGTCCTGTTGCCCTTTCTTCTGGTGACGCTGATCTGGGGGTCGACGTGG
ATCGTCATCAAGGGACAGCT

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTATRFFSDNAAAVHPAVMEALVAANHVDTAYDGDALSQSLDAAFSDLFETDCEVVWVSTGTAANSIILAHFVRPWQGIL
CYEEAHIEVDECGAPTFYSGGATLMPLPGRGAKIDTAALKARIAGIRQDVHQVQPAAVSITNATEYGLAWRPQEIGEISE
IARRKGLKLHMDGARFANAVAFLGCAPADVTWRAGVDALSFGFTKNGAMMAEAIVFFGGSGGAGVRELKKRGGHLLSKGR
FVAAQIRAMLKDDLWLANARAANAGAAKLAAACGSRLLYPVEANELFVRLSNDEAAKLRGAGFDFYDWGEGAARLVVSWD
QDAEAVAPLAAAIGAL

Sequences:

>Translated_336_residues
MTATRFFSDNAAAVHPAVMEALVAANHVDTAYDGDALSQSLDAAFSDLFETDCEVVWVSTGTAANSIILAHFVRPWQGIL
CYEEAHIEVDECGAPTFYSGGATLMPLPGRGAKIDTAALKARIAGIRQDVHQVQPAAVSITNATEYGLAWRPQEIGEISE
IARRKGLKLHMDGARFANAVAFLGCAPADVTWRAGVDALSFGFTKNGAMMAEAIVFFGGSGGAGVRELKKRGGHLLSKGR
FVAAQIRAMLKDDLWLANARAANAGAAKLAAACGSRLLYPVEANELFVRLSNDEAAKLRGAGFDFYDWGEGAARLVVSWD
QDAEAVAPLAAAIGAL
>Mature_335_residues
TATRFFSDNAAAVHPAVMEALVAANHVDTAYDGDALSQSLDAAFSDLFETDCEVVWVSTGTAANSIILAHFVRPWQGILC
YEEAHIEVDECGAPTFYSGGATLMPLPGRGAKIDTAALKARIAGIRQDVHQVQPAAVSITNATEYGLAWRPQEIGEISEI
ARRKGLKLHMDGARFANAVAFLGCAPADVTWRAGVDALSFGFTKNGAMMAEAIVFFGGSGGAGVRELKKRGGHLLSKGRF
VAAQIRAMLKDDLWLANARAANAGAAKLAAACGSRLLYPVEANELFVRLSNDEAAKLRGAGFDFYDWGEGAARLVVSWDQ
DAEAVAPLAAAIGAL

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=294, Percent_Identity=24.8299319727891, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35474; Mature: 35342

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATRFFSDNAAAVHPAVMEALVAANHVDTAYDGDALSQSLDAAFSDLFETDCEVVWVST
CCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
GTAANSIILAHFVRPWQGILCYEEAHIEVDECGAPTFYSGGATLMPLPGRGAKIDTAALK
CCCCCHHHHHHHHCCCCCEEEEEECCEEHHHCCCCCEECCCCEEEECCCCCCCCHHHHHH
ARIAGIRQDVHQVQPAAVSITNATEYGLAWRPQEIGEISEIARRKGLKLHMDGARFANAV
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHH
AFLGCAPADVTWRAGVDALSFGFTKNGAMMAEAIVFFGGSGGAGVRELKKRGGHLLSKGR
HHHCCCCCCCCHHCCCCHHHCCCCCCCHHEEEEEEEECCCCCCHHHHHHHCCCCCHHCCC
FVAAQIRAMLKDDLWLANARAANAGAAKLAAACGSRLLYPVEANELFVRLSNDEAAKLRG
HHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHCCCCEEEEEECCEEEEEECCCCHHHHCC
AGFDFYDWGEGAARLVVSWDQDAEAVAPLAAAIGAL
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATRFFSDNAAAVHPAVMEALVAANHVDTAYDGDALSQSLDAAFSDLFETDCEVVWVST
CCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
GTAANSIILAHFVRPWQGILCYEEAHIEVDECGAPTFYSGGATLMPLPGRGAKIDTAALK
CCCCCHHHHHHHHCCCCCEEEEEECCEEHHHCCCCCEECCCCEEEECCCCCCCCHHHHHH
ARIAGIRQDVHQVQPAAVSITNATEYGLAWRPQEIGEISEIARRKGLKLHMDGARFANAV
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHH
AFLGCAPADVTWRAGVDALSFGFTKNGAMMAEAIVFFGGSGGAGVRELKKRGGHLLSKGR
HHHCCCCCCCCHHCCCCHHHCCCCCCCHHEEEEEEEECCCCCCHHHHHHHCCCCCHHCCC
FVAAQIRAMLKDDLWLANARAANAGAAKLAAACGSRLLYPVEANELFVRLSNDEAAKLRG
HHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHCCCCEEEEEECCEEEEEECCCCHHHHCC
AGFDFYDWGEGAARLVVSWDQDAEAVAPLAAAIGAL
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]