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The map label for this gene is vvpD [H]

Identifier: 103485821

GI number: 103485821

Start: 332423

End: 333205

Strand: Direct

Name: vvpD [H]

Synonym: Sala_0326

Alternate gene names: 103485821

Gene position: 332423-333205 (Clockwise)

Preceding gene: 103485820

Following gene: 103485836

Centisome position: 9.94

GC content: 70.5

Gene sequence:

>783_bases
GTGGTCGACCAAAGCCTGAAAATCCTCGATGCCTTGCCCTTCGGCACGGGCATCCTGCTGGCCGGGCTGACCGGGCTGCT
GCTGGGCAGTTTTATAGCGACGCTGGTGCTGCGTTGGCCGGAGGGGCGCTCGCTGCTCGGGCGCTCGCAGTGCGACGGCT
GCGGACGGGCGCTCGGCGTGCGCGATCTTGTCCCGCTTGTATCGGCGGCGCTGTCGCGCGGGCGGTGCCGGACGTGCGGT
GCGAGGATCAACCCCTTTCATGGCCGGGTCGAGCTTGTATCGGCGCTGATTGGCGCCGGGGCGCTGGCGCTGCTTCCGGG
CACGGCGGGCTGGCTCTGGGCGCTGTTCGGCTGGTTGCTGCTGCCGCTCGCGCTGCTCGATGCGCGGCATTTCTGGCTGC
CCGACCGGCTGACGCTGTTGCTGGCGGTGACGGGGGTGTTGCTGGCGGGACCGATGCTCGGCACGTCACTGGTCGATCGC
TGGGTCGGAGCGCTGGTTGGCGGTGGCACGCTCGCGCTGCTCGCGTGGCTCTATGCGCGTGCGCGCCGACGGGAAGGCAT
GGGGGGCGGCGACCCCAAACTCGTCGCGGCGACGGGCGCGTGGCTCGGCTGGCAGGCCTTGCCGCTGATGCTGCTGCTCG
CGAGCCTTGGCGGAATCATCTGGGCGCTCGTCGTCCAGCGAAAAGGGGACCAGCCGCTCGGCGAGCGGCGAGTCCCCTTC
GGTATGTTCCTTTGCGGTGCCGCCTTTGCCGCGGTGCCGCTGTGGCCGCTTATCGCCCGATGA

Upstream 100 bases:

>100_bases
CAGCATATCCCGTTCGCGTCGAGCGAAGTCGAGACGCCGTGCCGGCCAGCCGGGCGTCTCGACTTCGCTCGACGCGAACG
GATTAGATCGCAATCGGGCG

Downstream 100 bases:

>100_bases
CGACGGTCACTGCGCGGCGGTTCTGCGCCCAGGCTTCCTCGTTCGAGCCGATCGCGGCGGGGCGTTCCTTGCCATAGCTG
ATGACATTGATCCGCGACGG

Product: peptidase A24A, prepilin type IV

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MVDQSLKILDALPFGTGILLAGLTGLLLGSFIATLVLRWPEGRSLLGRSQCDGCGRALGVRDLVPLVSAALSRGRCRTCG
ARINPFHGRVELVSALIGAGALALLPGTAGWLWALFGWLLLPLALLDARHFWLPDRLTLLLAVTGVLLAGPMLGTSLVDR
WVGALVGGGTLALLAWLYARARRREGMGGGDPKLVAATGAWLGWQALPLMLLLASLGGIIWALVVQRKGDQPLGERRVPF
GMFLCGAAFAAVPLWPLIAR

Sequences:

>Translated_260_residues
MVDQSLKILDALPFGTGILLAGLTGLLLGSFIATLVLRWPEGRSLLGRSQCDGCGRALGVRDLVPLVSAALSRGRCRTCG
ARINPFHGRVELVSALIGAGALALLPGTAGWLWALFGWLLLPLALLDARHFWLPDRLTLLLAVTGVLLAGPMLGTSLVDR
WVGALVGGGTLALLAWLYARARRREGMGGGDPKLVAATGAWLGWQALPLMLLLASLGGIIWALVVQRKGDQPLGERRVPF
GMFLCGAAFAAVPLWPLIAR
>Mature_260_residues
MVDQSLKILDALPFGTGILLAGLTGLLLGSFIATLVLRWPEGRSLLGRSQCDGCGRALGVRDLVPLVSAALSRGRCRTCG
ARINPFHGRVELVSALIGAGALALLPGTAGWLWALFGWLLLPLALLDARHFWLPDRLTLLLAVTGVLLAGPMLGTSLVDR
WVGALVGGGTLALLAWLYARARRREGMGGGDPKLVAATGAWLGWQALPLMLLLASLGGIIWALVVQRKGDQPLGERRVPF
GMFLCGAAFAAVPLWPLIAR

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=246, Percent_Identity=33.739837398374, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789732, Length=112, Percent_Identity=43.75, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 27476; Mature: 27476

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQSLKILDALPFGTGILLAGLTGLLLGSFIATLVLRWPEGRSLLGRSQCDGCGRALGV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHCCHHHHHCCH
RDLVPLVSAALSRGRCRTCGARINPFHGRVELVSALIGAGALALLPGTAGWLWALFGWLL
HHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
LPLALLDARHFWLPDRLTLLLAVTGVLLAGPMLGTSLVDRWVGALVGGGTLALLAWLYAR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARRREGMGGGDPKLVAATGAWLGWQALPLMLLLASLGGIIWALVVQRKGDQPLGERRVPF
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
GMFLCGAAFAAVPLWPLIAR
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDQSLKILDALPFGTGILLAGLTGLLLGSFIATLVLRWPEGRSLLGRSQCDGCGRALGV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHCCHHHHHCCH
RDLVPLVSAALSRGRCRTCGARINPFHGRVELVSALIGAGALALLPGTAGWLWALFGWLL
HHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
LPLALLDARHFWLPDRLTLLLAVTGVLLAGPMLGTSLVDRWVGALVGGGTLALLAWLYAR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARRREGMGGGDPKLVAATGAWLGWQALPLMLLLASLGGIIWALVVQRKGDQPLGERRVPF
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
GMFLCGAAFAAVPLWPLIAR
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9826339 [H]