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The map label for this gene is yggV [C]

Identifier: 103485752

GI number: 103485752

Start: 258677

End: 259309

Strand: Direct

Name: yggV [C]

Synonym: Sala_0257

Alternate gene names: 103485752

Gene position: 258677-259309 (Clockwise)

Preceding gene: 103485751

Following gene: 103485753

Centisome position: 7.73

GC content: 68.25

Gene sequence:

>633_bases
ATGGCTGCTCCTCATCGAAAACTCGCTCCCGGCAAACTGGTGATCGCCAGCCATAATGCGGGCAAGGTGCGCGAAATCCG
CGCGCTGCTCGCGCCTTACGGGGTCGATCCGGTATCGGCGGCCGACCTCGGCCTTCCCGAACCCGAGGAGACGGGGACGA
GCTTTCGCGACAATGCGCTGCTGAAGGCGCATGCGAGCGCGGCGGCGTCGGGGCTGCCCGCGCTCGCCGACGACAGCGGG
CTTTGCGTCGATGCGCTGGGCGGGCGGCCCGGCGTCTATACCGCCGACTGGGCCGAGCGGCAGTGGTTCGAGGGCAATCC
GGGCCGCGACTGGTATCTCGCGATGGGCAAGGTCGAGGGGCTGCTTGCCGAGCAGGGGCCGGACGTCGACCGCAGCGCAC
GCTTCGTTTGCACGTTGGCCCTCGCCTGGCCCGACGGCCATGCGGAGGTTTTCGAGGGCAGGGTCGAGGGCGGCCTGACC
TGGCCGCCGCGGGGCAAGCTGGGTTTCGGCTATGATCCGGTGTTCGTTCCGGCAGGAAAGACGTTGACGTTTGCCGAGAT
CGAACCCGCGGAAAAGCACGCGATCAGCCACCGCGCCGATGCGTTCGCGAAACTGGTGGCAGGGGTGTTCTGA

Upstream 100 bases:

>100_bases
TTCAAGCGCGCCGCATCGCCTACGCTGCACGCAAGGATCGTATGTTCCGTTCGCTGATCAGGAAACTCGATTCGATTCGA
GGCGACTTGTGACGGGGACA

Downstream 100 bases:

>100_bases
CGCCGCCCATGTTCGAACCTCTCGCCCTTTATGTTCATTGGCCGTTTTGCGTCAGCAAATGTCCTTATTGTGACTTCAAC
AGCCATGTGCGCGACAGCGT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MAAPHRKLAPGKLVIASHNAGKVREIRALLAPYGVDPVSAADLGLPEPEETGTSFRDNALLKAHASAAASGLPALADDSG
LCVDALGGRPGVYTADWAERQWFEGNPGRDWYLAMGKVEGLLAEQGPDVDRSARFVCTLALAWPDGHAEVFEGRVEGGLT
WPPRGKLGFGYDPVFVPAGKTLTFAEIEPAEKHAISHRADAFAKLVAGVF

Sequences:

>Translated_210_residues
MAAPHRKLAPGKLVIASHNAGKVREIRALLAPYGVDPVSAADLGLPEPEETGTSFRDNALLKAHASAAASGLPALADDSG
LCVDALGGRPGVYTADWAERQWFEGNPGRDWYLAMGKVEGLLAEQGPDVDRSARFVCTLALAWPDGHAEVFEGRVEGGLT
WPPRGKLGFGYDPVFVPAGKTLTFAEIEPAEKHAISHRADAFAKLVAGVF
>Mature_209_residues
AAPHRKLAPGKLVIASHNAGKVREIRALLAPYGVDPVSAADLGLPEPEETGTSFRDNALLKAHASAAASGLPALADDSGL
CVDALGGRPGVYTADWAERQWFEGNPGRDWYLAMGKVEGLLAEQGPDVDRSARFVCTLALAWPDGHAEVFEGRVEGGLTW
PPRGKLGFGYDPVFVPAGKTLTFAEIEPAEKHAISHRADAFAKLVAGVF

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=200, Percent_Identity=33, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI31657144, Length=135, Percent_Identity=38.5185185185185, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789324, Length=200, Percent_Identity=42, Blast_Score=136, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=31.6326530612245, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920712, Length=194, Percent_Identity=31.4432989690722, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22208; Mature: 22077

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPHRKLAPGKLVIASHNAGKVREIRALLAPYGVDPVSAADLGLPEPEETGTSFRDNAL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCHHCCCCCCCCCE
LKAHASAAASGLPALADDSGLCVDALGGRPGVYTADWAERQWFEGNPGRDWYLAMGKVEG
EEHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEECCHHCCCCCCCCCCCEEEEEECHHHH
LLAEQGPDVDRSARFVCTLALAWPDGHAEVFEGRVEGGLTWPPRGKLGFGYDPVFVPAGK
HHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
TLTFAEIEPAEKHAISHRADAFAKLVAGVF
EEEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAPHRKLAPGKLVIASHNAGKVREIRALLAPYGVDPVSAADLGLPEPEETGTSFRDNAL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCHHCCCCCCCCCE
LKAHASAAASGLPALADDSGLCVDALGGRPGVYTADWAERQWFEGNPGRDWYLAMGKVEG
EEHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEECCHHCCCCCCCCCCCEEEEEECHHHH
LLAEQGPDVDRSARFVCTLALAWPDGHAEVFEGRVEGGLTWPPRGKLGFGYDPVFVPAGK
HHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
TLTFAEIEPAEKHAISHRADAFAKLVAGVF
EEEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA