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The map label for this gene is ctaA

Identifier: 103485738

GI number: 103485738

Start: 247661

End: 248728

Strand: Direct

Name: ctaA

Synonym: Sala_0242

Alternate gene names: 103485738

Gene position: 247661-248728 (Clockwise)

Preceding gene: 103485731

Following gene: 103485739

Centisome position: 7.4

GC content: 67.98

Gene sequence:

>1068_bases
ATGACCAATAGCTCGGCCCTTTCTCCATCGTCCTCCGCAGTGGCGCCGCGCCCCGGCGCGCTGGCGCGCTGGCTGTGGGC
GGTCGCCCTGCTCGTGATCATCGTCGTGGGTGTGGGCGGCATCACGCGCCTCACCGAATCGGGGCTGTCGATCACCGAAT
GGCGCCCCGTGTCGGGGGTGCTGCCGCCGCTCAACGAAGCCGACTGGGTCAGGGAGTTCGAGAAATACAAGCAGATCCCT
GAATATAAGGAGATCAACCTCGGCATGACGCTGGCGGGGTTCAAGGCGATTTTTTTCTGGGAATGGCTGCACCGCATTCT
CGGCCGCGTCGTCGGCATGGCGCTGGTCGTCCCGTTCGTCTGGTATGCGTGGCGCCGCGCCATCCCCGCGGGTTACGGCT
GGCGGCTGTTCGCGCTGACCGCGCTCGTCGGCTTGCAGGGCGCGATCGGCTGGTGGATGGTGGCGTCGGGGCTGGAATAT
CGCACCGACGTCAGCCATTACCGCCTTGCGGCGCATCTGCTCACCGCGCTGTTCCTGCTCGCCGGGCTGGTGTGGACCGC
GCGTGATCTGGGGGCGCTTGCGCGCGATCCCGGTGCGCCGCCGGCGCGGCTGACGGGCGCCGCGATCGGCGTCATCGCGA
TCCTGTTCGTCCAGTTGCTGCTCGGTGCGTGGGTCGCCGGGCTCAATGCCGGCTATGTTTCGAGCAGCTGGCCGCTGATG
AACGATCATTTCGTGCCCGAAGGGATCGACTGGAGCGGCGGCGCGTGGCTTGCCCTCACCAACGATCCCTTCCTCATCCA
TTTCCTCCACCGTTGGTGGTCGTGGGCCGCGGCGGGCGCGCTGCTGCTGCTCGCCCGGACGCTGGCGCGACGCGGCGCGC
GCGCCGAAGCCTGCGCGCTCGTCATCGTCGTCGCGGCGCAGATGCTGCTCGGCATCTGGACCATTGTGTCGGGGGTGTCG
ATGTGGGTCGCGGTGATGCACCAGGTCGTCGGGGCAATCCTCGTCGCCGTCACGGCGGCGGCATTGCATCGGCTCGGCCG
CCGGTCAGCGATCACCGAGGTATCATAA

Upstream 100 bases:

>100_bases
CAAGCTGCATCTGTCGTCGCCATGAATATCGGGATCGGGCTCCTCTCTTGTCGGCTGTCCGCCTCTTGCCTATCGCCCGG
CAAGCGACGATAGGGCGGCC

Downstream 100 bases:

>100_bases
TACCCGTCAGCAAAGCCGCACGATACTTGACTTTCCGCGCGTCCGGCGTCATTGGCCCGCGTCGAAGCGCCGCTGAGTCC
GTTCGGAACAGGCGGCGCGG

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTNSSALSPSSSAVAPRPGALARWLWAVALLVIIVVGVGGITRLTESGLSITEWRPVSGVLPPLNEADWVREFEKYKQIP
EYKEINLGMTLAGFKAIFFWEWLHRILGRVVGMALVVPFVWYAWRRAIPAGYGWRLFALTALVGLQGAIGWWMVASGLEY
RTDVSHYRLAAHLLTALFLLAGLVWTARDLGALARDPGAPPARLTGAAIGVIAILFVQLLLGAWVAGLNAGYVSSSWPLM
NDHFVPEGIDWSGGAWLALTNDPFLIHFLHRWWSWAAAGALLLLARTLARRGARAEACALVIVVAAQMLLGIWTIVSGVS
MWVAVMHQVVGAILVAVTAAALHRLGRRSAITEVS

Sequences:

>Translated_355_residues
MTNSSALSPSSSAVAPRPGALARWLWAVALLVIIVVGVGGITRLTESGLSITEWRPVSGVLPPLNEADWVREFEKYKQIP
EYKEINLGMTLAGFKAIFFWEWLHRILGRVVGMALVVPFVWYAWRRAIPAGYGWRLFALTALVGLQGAIGWWMVASGLEY
RTDVSHYRLAAHLLTALFLLAGLVWTARDLGALARDPGAPPARLTGAAIGVIAILFVQLLLGAWVAGLNAGYVSSSWPLM
NDHFVPEGIDWSGGAWLALTNDPFLIHFLHRWWSWAAAGALLLLARTLARRGARAEACALVIVVAAQMLLGIWTIVSGVS
MWVAVMHQVVGAILVAVTAAALHRLGRRSAITEVS
>Mature_354_residues
TNSSALSPSSSAVAPRPGALARWLWAVALLVIIVVGVGGITRLTESGLSITEWRPVSGVLPPLNEADWVREFEKYKQIPE
YKEINLGMTLAGFKAIFFWEWLHRILGRVVGMALVVPFVWYAWRRAIPAGYGWRLFALTALVGLQGAIGWWMVASGLEYR
TDVSHYRLAAHLLTALFLLAGLVWTARDLGALARDPGAPPARLTGAAIGVIAILFVQLLLGAWVAGLNAGYVSSSWPLMN
DHFVPEGIDWSGGAWLALTNDPFLIHFLHRWWSWAAAGALLLLARTLARRGARAEACALVIVVAAQMLLGIWTIVSGVSM
WVAVMHQVVGAILVAVTAAALHRLGRRSAITEVS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=328, Percent_Identity=35.9756097560976, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI17921987, Length=287, Percent_Identity=36.9337979094077, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17536069, Length=345, Percent_Identity=33.9130434782609, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6320989, Length=349, Percent_Identity=35.243553008596, Blast_Score=188, Evalue=9e-49,
Organism=Drosophila melanogaster, GI19922860, Length=345, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_SPHAL (Q1GWK6)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615299.1
- GeneID:   4083101
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0242
- NMPDR:   fig|317655.9.peg.222
- HOGENOM:   HBG628966
- OMA:   PPMSEAA
- ProtClustDB:   CLSK2777816
- BioCyc:   SALA317655:SALA_0242-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 38552; Mature: 38421

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: BINDING 327-327

Signals:

None

Transmembrane regions:

HASH(0xddd0594)-; HASH(0xf6ce01c)-; HASH(0xd8faba0)-; HASH(0xf83df58)-; HASH(0xf98e040)-; HASH(0xf7e0790)-; HASH(0x1030c9bc)-; HASH(0xf84c248)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSSALSPSSSAVAPRPGALARWLWAVALLVIIVVGVGGITRLTESGLSITEWRPVSGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
LPPLNEADWVREFEKYKQIPEYKEINLGMTLAGFKAIFFWEWLHRILGRVVGMALVVPFV
CCCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYAWRRAIPAGYGWRLFALTALVGLQGAIGWWMVASGLEYRTDVSHYRLAAHLLTALFLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AGLVWTARDLGALARDPGAPPARLTGAAIGVIAILFVQLLLGAWVAGLNAGYVSSSWPLM
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NDHFVPEGIDWSGGAWLALTNDPFLIHFLHRWWSWAAAGALLLLARTLARRGARAEACAL
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VIVVAAQMLLGIWTIVSGVSMWVAVMHQVVGAILVAVTAAALHRLGRRSAITEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
TNSSALSPSSSAVAPRPGALARWLWAVALLVIIVVGVGGITRLTESGLSITEWRPVSGV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
LPPLNEADWVREFEKYKQIPEYKEINLGMTLAGFKAIFFWEWLHRILGRVVGMALVVPFV
CCCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYAWRRAIPAGYGWRLFALTALVGLQGAIGWWMVASGLEYRTDVSHYRLAAHLLTALFLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AGLVWTARDLGALARDPGAPPARLTGAAIGVIAILFVQLLLGAWVAGLNAGYVSSSWPLM
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NDHFVPEGIDWSGGAWLALTNDPFLIHFLHRWWSWAAAGALLLLARTLARRGARAEACAL
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VIVVAAQMLLGIWTIVSGVSMWVAVMHQVVGAILVAVTAAALHRLGRRSAITEVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA