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The map label for this gene is yfkF [H]

Identifier: 99080935

GI number: 99080935

Start: 1172453

End: 1173727

Strand: Direct

Name: yfkF [H]

Synonym: TM1040_1094

Alternate gene names: 99080935

Gene position: 1172453-1173727 (Clockwise)

Preceding gene: 99080934

Following gene: 99080936

Centisome position: 36.63

GC content: 61.41

Gene sequence:

>1275_bases
ATGCTGCAAGTTCTGTCGAGCGCCTGGGCGCTTTTGCTGGGCATTGGCCTTTTGATGTTGGGCAACGGCCTGCAAGGCAC
GCTGCTGGGTGTGCGCGGTGGCATCGAGGGCTATTCCGCGCTCACCATGTCGCTGGTGATGTCCACCTATTTTGTGGGCT
TGCTCCTGGGGTCCTGGGTGGCGCCGGGGATGATCCGGCGTGTGGGCCATGTGCGGGTCTTTGCGGCGCTGGCCTCGCTG
ATTTCGGCGGTGATGGTGATCTATCCCGCGCTGCCCAACCCGATTGTCTGGATGCTGGGCCGTCTGGTCGTGGGGTTCTG
CTTTTCTGGCGTGTATGTCACCGCCGAAAGCTGGCTCAACAATGCGGCTGACAACCAGAACCGAGGCAAGGCGCTCTCTC
TCTATATGGTCGTGATGACACTGGGGCTGGTGGCCGCACAGGGTTTCATCCTGATCGGGGACCCGGCGGGCTATCTGCCG
TTTGTGATCGCCTCCATCGCGGTTTCGATCTCCTTCGCCCCGATTTTGCTGTCGATTTCGCCGACCCCCGCCTTTGATAC
GGCCAAGCGGATGACGCTTCGCGAATTGATGCATGCCTCGCCCCTTGGGTGTGTGGGGATGTTCCTCATTGGCGGCGTGT
TCTCGGCGCAGTTTGGTATGTCTGCGGTCTATGCCACCGAGGCTGGGATGGAGCTGCATCAGGTTTCGCTCTTTGCGGCG
AGCTTCTATGTCGGTGCGCTCTTTATGCAGTTCCCGCTGGGGCTGCTGTCCGACCGGATGGATCGACGGGTGCTGATCAT
GATCGTGGCAGGGGTCGCCGGGGTGACCTCGGTGCTGGCGATGCTGCTTGGGGGCACGTTCAGCCTGCTTCTGCTGGCCG
CCTTTGTGATCGGCGGGCTGATCAACCCGCTCTATTCCTTGCTCCTGGCCCACACCAATGACTTTCTCGATCACGACGAT
ATGGCCTCTGCCTCGGGCGGGCTGATCTTTATCAACGGGCTTGGCGCCTGTAGCGGGCCGGTCATCATCGGCTGGCTGAT
GTCGGACGCGATGTTCGGACCCAACGGGTTCTTCCTCTTCATGGCGATATTGCTGGGCGTGTTGGTTCTTTATGCCGGGT
ATCGCGCAACGCAGCGTGCGACCATTCCAGTCGAAGAGACCGGTGTCATGCCCGCCATGAGCCCGACCGCGACCTCGGTC
GCGGTAGAGGTGGCGCAGGAATACGCCATCGAAACCGAGCTCGAAGAGCAAGACAGCGCCACAACCACGGGCTGA

Upstream 100 bases:

>100_bases
CCCTCTGACAGCCCACCGCGGCCTCGGGCCGGTTTTACTGAAAATACTTCCCGTATGCCGCTGTGCTGCGGGCTCCTCAC
GGACCGAAGGAGAACACGTC

Downstream 100 bases:

>100_bases
CGGCAATAACCTGCTGAAAAATTGGCCATCTCTTCACAAAAGTGACGGAGGTGGCCTTTTTTGTAACGTAACGTCACTTG
TGCTTGGGGGGTGAATCAGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MLQVLSSAWALLLGIGLLMLGNGLQGTLLGVRGGIEGYSALTMSLVMSTYFVGLLLGSWVAPGMIRRVGHVRVFAALASL
ISAVMVIYPALPNPIVWMLGRLVVGFCFSGVYVTAESWLNNAADNQNRGKALSLYMVVMTLGLVAAQGFILIGDPAGYLP
FVIASIAVSISFAPILLSISPTPAFDTAKRMTLRELMHASPLGCVGMFLIGGVFSAQFGMSAVYATEAGMELHQVSLFAA
SFYVGALFMQFPLGLLSDRMDRRVLIMIVAGVAGVTSVLAMLLGGTFSLLLLAAFVIGGLINPLYSLLLAHTNDFLDHDD
MASASGGLIFINGLGACSGPVIIGWLMSDAMFGPNGFFLFMAILLGVLVLYAGYRATQRATIPVEETGVMPAMSPTATSV
AVEVAQEYAIETELEEQDSATTTG

Sequences:

>Translated_424_residues
MLQVLSSAWALLLGIGLLMLGNGLQGTLLGVRGGIEGYSALTMSLVMSTYFVGLLLGSWVAPGMIRRVGHVRVFAALASL
ISAVMVIYPALPNPIVWMLGRLVVGFCFSGVYVTAESWLNNAADNQNRGKALSLYMVVMTLGLVAAQGFILIGDPAGYLP
FVIASIAVSISFAPILLSISPTPAFDTAKRMTLRELMHASPLGCVGMFLIGGVFSAQFGMSAVYATEAGMELHQVSLFAA
SFYVGALFMQFPLGLLSDRMDRRVLIMIVAGVAGVTSVLAMLLGGTFSLLLLAAFVIGGLINPLYSLLLAHTNDFLDHDD
MASASGGLIFINGLGACSGPVIIGWLMSDAMFGPNGFFLFMAILLGVLVLYAGYRATQRATIPVEETGVMPAMSPTATSV
AVEVAQEYAIETELEEQDSATTTG
>Mature_424_residues
MLQVLSSAWALLLGIGLLMLGNGLQGTLLGVRGGIEGYSALTMSLVMSTYFVGLLLGSWVAPGMIRRVGHVRVFAALASL
ISAVMVIYPALPNPIVWMLGRLVVGFCFSGVYVTAESWLNNAADNQNRGKALSLYMVVMTLGLVAAQGFILIGDPAGYLP
FVIASIAVSISFAPILLSISPTPAFDTAKRMTLRELMHASPLGCVGMFLIGGVFSAQFGMSAVYATEAGMELHQVSLFAA
SFYVGALFMQFPLGLLSDRMDRRVLIMIVAGVAGVTSVLAMLLGGTFSLLLLAAFVIGGLINPLYSLLLAHTNDFLDHDD
MASASGGLIFINGLGACSGPVIIGWLMSDAMFGPNGFFLFMAILLGVLVLYAGYRATQRATIPVEETGVMPAMSPTATSV
AVEVAQEYAIETELEEQDSATTTG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787126, Length=339, Percent_Identity=24.188790560472, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44640; Mature: 44640

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVLSSAWALLLGIGLLMLGNGLQGTLLGVRGGIEGYSALTMSLVMSTYFVGLLLGSWV
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APGMIRRVGHVRVFAALASLISAVMVIYPALPNPIVWMLGRLVVGFCFSGVYVTAESWLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHC
NAADNQNRGKALSLYMVVMTLGLVAAQGFILIGDPAGYLPFVIASIAVSISFAPILLSIS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEECC
PTPAFDTAKRMTLRELMHASPLGCVGMFLIGGVFSAQFGMSAVYATEAGMELHQVSLFAA
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
SFYVGALFMQFPLGLLSDRMDRRVLIMIVAGVAGVTSVLAMLLGGTFSLLLLAAFVIGGL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
INPLYSLLLAHTNDFLDHDDMASASGGLIFINGLGACSGPVIIGWLMSDAMFGPNGFFLF
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHH
MAILLGVLVLYAGYRATQRATIPVEETGVMPAMSPTATSVAVEVAQEYAIETELEEQDSA
HHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TTTG
CCCC
>Mature Secondary Structure
MLQVLSSAWALLLGIGLLMLGNGLQGTLLGVRGGIEGYSALTMSLVMSTYFVGLLLGSWV
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APGMIRRVGHVRVFAALASLISAVMVIYPALPNPIVWMLGRLVVGFCFSGVYVTAESWLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEHHHHHC
NAADNQNRGKALSLYMVVMTLGLVAAQGFILIGDPAGYLPFVIASIAVSISFAPILLSIS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEECC
PTPAFDTAKRMTLRELMHASPLGCVGMFLIGGVFSAQFGMSAVYATEAGMELHQVSLFAA
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
SFYVGALFMQFPLGLLSDRMDRRVLIMIVAGVAGVTSVLAMLLGGTFSLLLLAAFVIGGL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
INPLYSLLLAHTNDFLDHDDMASASGGLIFINGLGACSGPVIIGWLMSDAMFGPNGFFLF
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHH
MAILLGVLVLYAGYRATQRATIPVEETGVMPAMSPTATSVAVEVAQEYAIETELEEQDSA
HHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TTTG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]