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The map label for this gene is yheS [H]

Identifier: 99080795

GI number: 99080795

Start: 1017923

End: 1019824

Strand: Reverse

Name: yheS [H]

Synonym: TM1040_0954

Alternate gene names: 99080795

Gene position: 1019824-1017923 (Counterclockwise)

Preceding gene: 99080799

Following gene: 99080794

Centisome position: 31.86

GC content: 61.3

Gene sequence:

>1902_bases
ATGCCTTTCGACATGAGAGACGCCATGCTCAGGATCGAAAACATCACTTATTCCGTCGAAGGCCGCCCCCTTATGGAGGA
GGCCTCTGCCAGCATTCCAACCGGTCACAAGGTTGGCGTTGTCGGACGCAATGGCACCGGCAAGTCCACGCTGTTCCGCC
TGATCCGGGGCGAACTGGCGCTGGAAGGCGGAACAATCACCCTGCCCTCCAAGGCGCGGATTGGCGGCGTTGCGCAGGAA
GTGCCCTCCTCGGAGGTGTCGCTGATCGACACGGTGCTGGCCGCAGATACCGAACGTGCCGCGCTGATGGCGGAGGCCGA
CACCGCAACGGATGGCACCCGGATCGCCGAGATCCAGACCCGTCTGGTGGATATTGATGCATGGTCTGCTGAGGCCCGCG
CCGCTTCGATCCTCAAGGGGCTTGGCTTTGACGATCAGGATCAGCTGCGTCCCTGTTCTGACTTTTCGGGCGGCTGGCGC
ATGCGGGTGGCCCTTGCAGCGGTCCTGTTTGCGCAGCCCGACCTGCTGCTCCTCGATGAGCCGACGAACTACCTCGATCT
CGAAGGTGCGCTCTGGCTTGAAAGCTATATCGCGCGCTATCCGCACACGGTTCTGATCGTCTCCCACGACCGCGGGCTTC
TCAATCGCGCGGTGAGCGCCATCCTGCATCTCGAGGATCGCAAGCTCACGCTCTATCAGGGGCCTTACGACACTTTTGCC
GAGACCCGCGCCGCCCGCATCGCCGTGGCGCAGTCCGAAGCGCAGAAACAGGAAAACCGCCGCGCGCATCTTCAGAGCTT
TGTGGATCGCTTCCGCGCCAAGGCCTCCAAGGCCAAGCAGGCCCAATCGCGCCTGAAAATGATCGAGAAGATGAAGCCGA
TCTCGACCCCGCAAGAAGCAGCGCTGCGTGCCTTCAGCTTTCCCGAACCTGAGGAGATGTCGCCGCCGATCATCCAGATC
GAAGGCGGGATCACCGGCTACGGTGATGTGGAGATCTTGCGGCGTCTGAACCTGCGGATTGATCAGGACGACCGGATCGC
GCTGCTGGGCAAGAACGGTCAGGGCAAATCCACGCTCTCCAAGCTGCTCTCGGACCGGCTGCCTTTGATGGCGGGCAAAA
TGGTGCGCTCTTCAAAGCTCAGGATCGGCTATTTTGCGCAGCATCAGGTGGATGAGCTTTATATCAATGAGACCCCGCTG
GACCATCTGCGCCGCCTGCGCCCTGACGAGCCGCCCGCAAAATGGCGCGCGCGCCTTGCAGGCTTTGGCCTGGGCGCCCA
GCAGGCAGAAGTAGAGGTAAAGCGTCTGTCGGGAGGGCAGAAGGCCCGCCTGAGCCTCCTGCTTGCGACCCTTGATGCGC
CGCATATGCTGATCCTCGACGAGCCGACGAACCACCTCGACATCGAAAGCCGCGAAGCATTGGTCGAGGCACTGACCGCC
TATAGCGGCGCGGTCATCCTTGTGAGCCATGACATGCATCTTCTGAGCATGGTGGCCGATCGTCTGTGGCTGGTCTCGGA
GGGAACCGTCAAACCCTATGACGGCGATCTCGACAGCTATCGCGAGATGCTTCTGGCGCGCGACAAACCCGCCGCCAAGG
CCGCAACTGTGGCTGCAAGTGCAGCCGAGAAACGCACTGAGAAACCCAAACGCGCCAGTCGCGATCAGCTCCTTGCGCTG
CGCTCGGAAGTGCGAAAATCCGAGGCGCGGGTGGAAAAACTCAGCGAAATGCGCGAAAAACTGGATGCCAAGCTCGCGGA
CCCTGCCCTCTATGAAAGTGGCAAACAGGCCGACATCGAAGTTTGGCAGAAAAAGCATGCCGAGTGCATCGAGGCCTTGG
AGCGCGCGGAAGCGATCTGGATGGACGCGCTGGAAAAACTGGAGCTAGCAGAAACCTCATGA

Upstream 100 bases:

>100_bases
CGCGCGCGGATCGCCAAGGCGGGAATACCCGCCCCATGGCGCGCAAGACATCCGGGCTGACAAAGGACCTGCAAAGATAG
GATAGTGATTGACCCTCTCG

Downstream 100 bases:

>100_bases
TTGATACCGCGTTTCTGATTACCTCTTTTGTGACGCTATTTGTGATCATCGACCCGATTGGATTGATGCCGGTGTTCCTG
GCCCTGACCCAAGGCATGAC

Product: ABC transporter related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MPFDMRDAMLRIENITYSVEGRPLMEEASASIPTGHKVGVVGRNGTGKSTLFRLIRGELALEGGTITLPSKARIGGVAQE
VPSSEVSLIDTVLAADTERAALMAEADTATDGTRIAEIQTRLVDIDAWSAEARAASILKGLGFDDQDQLRPCSDFSGGWR
MRVALAAVLFAQPDLLLLDEPTNYLDLEGALWLESYIARYPHTVLIVSHDRGLLNRAVSAILHLEDRKLTLYQGPYDTFA
ETRAARIAVAQSEAQKQENRRAHLQSFVDRFRAKASKAKQAQSRLKMIEKMKPISTPQEAALRAFSFPEPEEMSPPIIQI
EGGITGYGDVEILRRLNLRIDQDDRIALLGKNGQGKSTLSKLLSDRLPLMAGKMVRSSKLRIGYFAQHQVDELYINETPL
DHLRRLRPDEPPAKWRARLAGFGLGAQQAEVEVKRLSGGQKARLSLLLATLDAPHMLILDEPTNHLDIESREALVEALTA
YSGAVILVSHDMHLLSMVADRLWLVSEGTVKPYDGDLDSYREMLLARDKPAAKAATVAASAAEKRTEKPKRASRDQLLAL
RSEVRKSEARVEKLSEMREKLDAKLADPALYESGKQADIEVWQKKHAECIEALERAEAIWMDALEKLELAETS

Sequences:

>Translated_633_residues
MPFDMRDAMLRIENITYSVEGRPLMEEASASIPTGHKVGVVGRNGTGKSTLFRLIRGELALEGGTITLPSKARIGGVAQE
VPSSEVSLIDTVLAADTERAALMAEADTATDGTRIAEIQTRLVDIDAWSAEARAASILKGLGFDDQDQLRPCSDFSGGWR
MRVALAAVLFAQPDLLLLDEPTNYLDLEGALWLESYIARYPHTVLIVSHDRGLLNRAVSAILHLEDRKLTLYQGPYDTFA
ETRAARIAVAQSEAQKQENRRAHLQSFVDRFRAKASKAKQAQSRLKMIEKMKPISTPQEAALRAFSFPEPEEMSPPIIQI
EGGITGYGDVEILRRLNLRIDQDDRIALLGKNGQGKSTLSKLLSDRLPLMAGKMVRSSKLRIGYFAQHQVDELYINETPL
DHLRRLRPDEPPAKWRARLAGFGLGAQQAEVEVKRLSGGQKARLSLLLATLDAPHMLILDEPTNHLDIESREALVEALTA
YSGAVILVSHDMHLLSMVADRLWLVSEGTVKPYDGDLDSYREMLLARDKPAAKAATVAASAAEKRTEKPKRASRDQLLAL
RSEVRKSEARVEKLSEMREKLDAKLADPALYESGKQADIEVWQKKHAECIEALERAEAIWMDALEKLELAETS
>Mature_632_residues
PFDMRDAMLRIENITYSVEGRPLMEEASASIPTGHKVGVVGRNGTGKSTLFRLIRGELALEGGTITLPSKARIGGVAQEV
PSSEVSLIDTVLAADTERAALMAEADTATDGTRIAEIQTRLVDIDAWSAEARAASILKGLGFDDQDQLRPCSDFSGGWRM
RVALAAVLFAQPDLLLLDEPTNYLDLEGALWLESYIARYPHTVLIVSHDRGLLNRAVSAILHLEDRKLTLYQGPYDTFAE
TRAARIAVAQSEAQKQENRRAHLQSFVDRFRAKASKAKQAQSRLKMIEKMKPISTPQEAALRAFSFPEPEEMSPPIIQIE
GGITGYGDVEILRRLNLRIDQDDRIALLGKNGQGKSTLSKLLSDRLPLMAGKMVRSSKLRIGYFAQHQVDELYINETPLD
HLRRLRPDEPPAKWRARLAGFGLGAQQAEVEVKRLSGGQKARLSLLLATLDAPHMLILDEPTNHLDIESREALVEALTAY
SGAVILVSHDMHLLSMVADRLWLVSEGTVKPYDGDLDSYREMLLARDKPAAKAATVAASAAEKRTEKPKRASRDQLLALR
SEVRKSEARVEKLSEMREKLDAKLADPALYESGKQADIEVWQKKHAECIEALERAEAIWMDALEKLELAETS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=532, Percent_Identity=40.0375939849624, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI10947137, Length=530, Percent_Identity=34.9056603773585, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI27881506, Length=530, Percent_Identity=34.9056603773585, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI69354671, Length=544, Percent_Identity=36.7647058823529, Blast_Score=300, Evalue=3e-81,
Organism=Homo sapiens, GI10947135, Length=544, Percent_Identity=36.7647058823529, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI105990541, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI21536376, Length=180, Percent_Identity=30.5555555555556, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1789751, Length=615, Percent_Identity=42.7642276422764, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=34.280303030303, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1787182, Length=590, Percent_Identity=28.9830508474576, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI2367384, Length=558, Percent_Identity=28.494623655914, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=32.0197044334975, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=27.3127753303965, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788506, Length=273, Percent_Identity=27.1062271062271, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786319, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=30.0469483568075, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=192, Percent_Identity=31.7708333333333, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787758, Length=204, Percent_Identity=29.9019607843137, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=533, Percent_Identity=39.0243902439024, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17559834, Length=553, Percent_Identity=36.3471971066908, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=36.0531309297913, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17565586, Length=205, Percent_Identity=28.2926829268293, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532409, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532411, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=540, Percent_Identity=38.1481481481481, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=32.3251417769376, Blast_Score=304, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6325030, Length=399, Percent_Identity=29.3233082706767, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324314, Length=389, Percent_Identity=25.9640102827763, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6323278, Length=382, Percent_Identity=25.9162303664921, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=40.7547169811321, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24641342, Length=554, Percent_Identity=37.0036101083032, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24642252, Length=531, Percent_Identity=35.2165725047081, Blast_Score=335, Evalue=8e-92,
Organism=Drosophila melanogaster, GI18859989, Length=531, Percent_Identity=35.2165725047081, Blast_Score=335, Evalue=8e-92,
Organism=Drosophila melanogaster, GI28574150, Length=198, Percent_Identity=30.8080808080808, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007328, Length=198, Percent_Identity=30.8080808080808, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70132; Mature: 70001

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDMRDAMLRIENITYSVEGRPLMEEASASIPTGHKVGVVGRNGTGKSTLFRLIRGELA
CCCCHHHHHHHHHCEEEEECCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHE
LEGGTITLPSKARIGGVAQEVPSSEVSLIDTVLAADTERAALMAEADTATDGTRIAEIQT
ECCCEEECCCCHHHCCHHHHCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCHHEEHH
RLVDIDAWSAEARAASILKGLGFDDQDQLRPCSDFSGGWRMRVALAAVLFAQPDLLLLDE
HEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PTNYLDLEGALWLESYIARYPHTVLIVSHDRGLLNRAVSAILHLEDRKLTLYQGPYDTFA
CCCEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHH
ETRAARIAVAQSEAQKQENRRAHLQSFVDRFRAKASKAKQAQSRLKMIEKMKPISTPQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALRAFSFPEPEEMSPPIIQIEGGITGYGDVEILRRLNLRIDQDDRIALLGKNGQGKSTLS
HHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCEECCCCCEEEEECCCCCHHHHH
KLLSDRLPLMAGKMVRSSKLRIGYFAQHQVDELYINETPLDHLRRLRPDEPPAKWRARLA
HHHHHCCCHHHHHHHHCCCCEEEEEHHHCHHHEEECCCCHHHHHHCCCCCCCHHHHHHHH
GFGLGAQQAEVEVKRLSGGQKARLSLLLATLDAPHMLILDEPTNHLDIESREALVEALTA
HCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
YSGAVILVSHDMHLLSMVADRLWLVSEGTVKPYDGDLDSYREMLLARDKPAAKAATVAAS
CCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AAEKRTEKPKRASRDQLLALRSEVRKSEARVEKLSEMREKLDAKLADPALYESGKQADIE
HHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHH
VWQKKHAECIEALERAEAIWMDALEKLELAETS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFDMRDAMLRIENITYSVEGRPLMEEASASIPTGHKVGVVGRNGTGKSTLFRLIRGELA
CCCHHHHHHHHHCEEEEECCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHE
LEGGTITLPSKARIGGVAQEVPSSEVSLIDTVLAADTERAALMAEADTATDGTRIAEIQT
ECCCEEECCCCHHHCCHHHHCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCHHEEHH
RLVDIDAWSAEARAASILKGLGFDDQDQLRPCSDFSGGWRMRVALAAVLFAQPDLLLLDE
HEEEEECCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PTNYLDLEGALWLESYIARYPHTVLIVSHDRGLLNRAVSAILHLEDRKLTLYQGPYDTFA
CCCEEECCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHH
ETRAARIAVAQSEAQKQENRRAHLQSFVDRFRAKASKAKQAQSRLKMIEKMKPISTPQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALRAFSFPEPEEMSPPIIQIEGGITGYGDVEILRRLNLRIDQDDRIALLGKNGQGKSTLS
HHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCEECCCCCEEEEECCCCCHHHHH
KLLSDRLPLMAGKMVRSSKLRIGYFAQHQVDELYINETPLDHLRRLRPDEPPAKWRARLA
HHHHHCCCHHHHHHHHCCCCEEEEEHHHCHHHEEECCCCHHHHHHCCCCCCCHHHHHHHH
GFGLGAQQAEVEVKRLSGGQKARLSLLLATLDAPHMLILDEPTNHLDIESREALVEALTA
HCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
YSGAVILVSHDMHLLSMVADRLWLVSEGTVKPYDGDLDSYREMLLARDKPAAKAATVAAS
CCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AAEKRTEKPKRASRDQLLALRSEVRKSEARVEKLSEMREKLDAKLADPALYESGKQADIE
HHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHH
VWQKKHAECIEALERAEAIWMDALEKLELAETS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]