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The map label for this gene is fur [H]

Identifier: 99080769

GI number: 99080769

Start: 991564

End: 991980

Strand: Direct

Name: fur [H]

Synonym: TM1040_0928

Alternate gene names: 99080769

Gene position: 991564-991980 (Clockwise)

Preceding gene: 99080767

Following gene: 99080770

Centisome position: 30.98

GC content: 58.75

Gene sequence:

>417_bases
ATGACCGACACGATAATCTCGCGCTGTGAGGCCCATGGCCTGCGTATGACCGGCCCGCGCCGCACCATTGCGCGTGTTCT
GGAGGAAAGCGACGATCACCCCGATGTCGAAGAGCTGCATGCGCGCGCCAATGCGCAGGATTCGGGGATCTCGCTGGCGA
CGGTCTACCGCACCGTCAAACTCTTTGAGGAATCAGGCATTCTGGAACGGCTCGAGTTTGGCGATGGCCGGGCGCGCTAT
GAGGATGCCGACCGCGATCATCACGACCATCTCATTGATCTGAACACGGGCGAGGTGATCGAGTTCTGTGATCCGGATAT
TGAGGAGCTGCAGGAACGCATTGCCAAAAAGCTCGGCTATGAGCTGCGCGGTCATAAGCTCGAACTCTATGGCGTGCCGA
TCAAAAAGGGCAGCTGA

Upstream 100 bases:

>100_bases
TGGTGTGCGGGCAAGATGGCTGTTTGCTATGCGTCTTGCATTCGCTAAAAAGAAACGCCAAGCAAGGGACCCCGCATCGA
ACGACAGGGACAGATCAGGC

Downstream 100 bases:

>100_bases
GCGGGCGCGGTTCGGGTCGCAGCCTGAGGGTCTCATCACCATCGTGAATAGAAAACCTCACAACTTCTGCTGAGGCAGGT
GCGATTTCACGCTTGCGTCA

Product: FUR family manganese uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTDTIISRCEAHGLRMTGPRRTIARVLEESDDHPDVEELHARANAQDSGISLATVYRTVKLFEESGILERLEFGDGRARY
EDADRDHHDHLIDLNTGEVIEFCDPDIEELQERIAKKLGYELRGHKLELYGVPIKKGS

Sequences:

>Translated_138_residues
MTDTIISRCEAHGLRMTGPRRTIARVLEESDDHPDVEELHARANAQDSGISLATVYRTVKLFEESGILERLEFGDGRARY
EDADRDHHDHLIDLNTGEVIEFCDPDIEELQERIAKKLGYELRGHKLELYGVPIKKGS
>Mature_137_residues
TDTIISRCEAHGLRMTGPRRTIARVLEESDDHPDVEELHARANAQDSGISLATVYRTVKLFEESGILERLEFGDGRARYE
DADRDHHDHLIDLNTGEVIEFCDPDIEELQERIAKKLGYELRGHKLELYGVPIKKGS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=132, Percent_Identity=43.9393939393939, Blast_Score=95, Evalue=1e-21,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15713; Mature: 15582

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIISRCEAHGLRMTGPRRTIARVLEESDDHPDVEELHARANAQDSGISLATVYRTVK
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
LFEESGILERLEFGDGRARYEDADRDHHDHLIDLNTGEVIEFCDPDIEELQERIAKKLGY
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHCC
ELRGHKLELYGVPIKKGS
HHCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TDTIISRCEAHGLRMTGPRRTIARVLEESDDHPDVEELHARANAQDSGISLATVYRTVK
CHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
LFEESGILERLEFGDGRARYEDADRDHHDHLIDLNTGEVIEFCDPDIEELQERIAKKLGY
HHHHCCHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHCC
ELRGHKLELYGVPIKKGS
HHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]