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The map label for this gene is anmK

Identifier: 99080765

GI number: 99080765

Start: 986286

End: 987413

Strand: Direct

Name: anmK

Synonym: TM1040_0924

Alternate gene names: 99080765

Gene position: 986286-987413 (Clockwise)

Preceding gene: 99080761

Following gene: 99080767

Centisome position: 30.81

GC content: 65.07

Gene sequence:

>1128_bases
ATGGGCAGAGCCATATCCAAGTCAGGCCCGGTGCGGGCCTTGGGCGCCATGAGCGGGACATCGCTTGACGGGGTCGACGT
CGCAGTTCTGGAAACCGACGGGCGCGACATTCTCGGCTTTGGAGAGACGGGCTACCGCGCCTATTCGGACGCGGAGCGGG
AGGTGTTGCGGGCCGCGCTGGGCCAGTGGACCGGCGATGCAGTCGCGGCGGCGGCGCGGGTGGTCGAGGCGGCGCATATC
GAGGTGATGACGGACCACGCCGATGTGGATCTCATCGGTTTTCATGGCCAGACCGTTGCACATGCCCCGCGTCTTCAGGG
CACGTTGCAGGTTGGCGATGGTGGTGTGCTGGCCGAGGCCTTGGGGCGGCCTGTGGTCTGGGACTTTCGCTCTGATGATG
TGTCGATGGGCGGCGAGGGCGCACCGCTCGCGCCTTTCTTCCATCATGCCTGCGCGCGCTATATCGGCGCGACAGAGCCC
TTGTGTTTTCTGAACCTCGGCGGGGTCGGCAACGTGACCTATGTTGATCCCCGCAAGGCCCGGCCCGAAGACGAAGGGGC
GCTTCTGGCGTTCGATACCGGGCCTGCCAATGCGCCGATCAACGACTTTCTTCAGTCCCGTCTCGGTCTTGCGATGGACG
AAGGCGGTAGGATTGCATCCGGGGGCGCGGTGGAAAACGGCGCGCTGGAGCTGTTTCTCGCCGAGCCCTATTTTGCGCGG
ATGCCACCCAAATCTCTGGATCGAAACGATTTCCCCGAGATGATCGGACTCGTGACCGAGCTCAGCGATGCGGATGCCAC
CGCGACACTTACCGCCATGTGTGCTGCAGCCGTGGCGCAAGGCATGGAGCATTGTCCCAAGGCACCGTCAAAGGTGCTTG
TCACCGGCGGTGGGCGGCACAATCCGGTGCTGATGGAAATGCTGCGGGTGTCGCTTGATTGCCCGGTAGAGCCGGTGGAA
ACGGTGGGGCTCGATGGGGACATGTTGGAAGCGCAGGCGTTTGCCTACCTCGCGGTCAGGGTGGCGCGCGGCCTTCCGAC
CTCAGCGCCCAGCACGACCGGCGTGCGCGCCTGCGTCGGCGGCGGGACGGTGACCGTTCCCGAAGGATGGACAGCGCGCA
AAACCTGA

Upstream 100 bases:

>100_bases
CATCGACACCGGTGGGAACCTGTTTTCGGGACAAAATGTGCGGTGTATCATGTGCCGCAACGGGCGGGACGGCCCGGTTT
TCGCAAGGAAGAGTGCAGAG

Downstream 100 bases:

>100_bases
TCGTTTAACTTCGGGGTATACCTGCAATTAGTTTGGCGGGCCAGCTCCCGCCCGTCGCGGGCTGCATATGAAATGCACCC
GCTCCCGATGGGCCAGGCGC

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MGRAISKSGPVRALGAMSGTSLDGVDVAVLETDGRDILGFGETGYRAYSDAEREVLRAALGQWTGDAVAAAARVVEAAHI
EVMTDHADVDLIGFHGQTVAHAPRLQGTLQVGDGGVLAEALGRPVVWDFRSDDVSMGGEGAPLAPFFHHACARYIGATEP
LCFLNLGGVGNVTYVDPRKARPEDEGALLAFDTGPANAPINDFLQSRLGLAMDEGGRIASGGAVENGALELFLAEPYFAR
MPPKSLDRNDFPEMIGLVTELSDADATATLTAMCAAAVAQGMEHCPKAPSKVLVTGGGRHNPVLMEMLRVSLDCPVEPVE
TVGLDGDMLEAQAFAYLAVRVARGLPTSAPSTTGVRACVGGGTVTVPEGWTARKT

Sequences:

>Translated_375_residues
MGRAISKSGPVRALGAMSGTSLDGVDVAVLETDGRDILGFGETGYRAYSDAEREVLRAALGQWTGDAVAAAARVVEAAHI
EVMTDHADVDLIGFHGQTVAHAPRLQGTLQVGDGGVLAEALGRPVVWDFRSDDVSMGGEGAPLAPFFHHACARYIGATEP
LCFLNLGGVGNVTYVDPRKARPEDEGALLAFDTGPANAPINDFLQSRLGLAMDEGGRIASGGAVENGALELFLAEPYFAR
MPPKSLDRNDFPEMIGLVTELSDADATATLTAMCAAAVAQGMEHCPKAPSKVLVTGGGRHNPVLMEMLRVSLDCPVEPVE
TVGLDGDMLEAQAFAYLAVRVARGLPTSAPSTTGVRACVGGGTVTVPEGWTARKT
>Mature_374_residues
GRAISKSGPVRALGAMSGTSLDGVDVAVLETDGRDILGFGETGYRAYSDAEREVLRAALGQWTGDAVAAAARVVEAAHIE
VMTDHADVDLIGFHGQTVAHAPRLQGTLQVGDGGVLAEALGRPVVWDFRSDDVSMGGEGAPLAPFFHHACARYIGATEPL
CFLNLGGVGNVTYVDPRKARPEDEGALLAFDTGPANAPINDFLQSRLGLAMDEGGRIASGGAVENGALELFLAEPYFARM
PPKSLDRNDFPEMIGLVTELSDADATATLTAMCAAAVAQGMEHCPKAPSKVLVTGGGRHNPVLMEMLRVSLDCPVEPVET
VGLDGDMLEAQAFAYLAVRVARGLPTSAPSTTGVRACVGGGTVTVPEGWTARKT

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=372, Percent_Identity=33.0645161290323, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_SILST (Q1GI59)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612919.1
- ProteinModelPortal:   Q1GI59
- SMR:   Q1GI59
- STRING:   Q1GI59
- GeneID:   4077552
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0924
- NMPDR:   fig|292414.1.peg.3004
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- PhylomeDB:   Q1GI59
- ProtClustDB:   PRK09585
- BioCyc:   SSP292414:TM1040_0924-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 39012; Mature: 38880

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAISKSGPVRALGAMSGTSLDGVDVAVLETDGRDILGFGETGYRAYSDAEREVLRAAL
CCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHH
GQWTGDAVAAAARVVEAAHIEVMTDHADVDLIGFHGQTVAHAPRLQGTLQVGDGGVLAEA
CCCCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCHHCCCCCCEEEEECCCCHHHHH
LGRPVVWDFRSDDVSMGGEGAPLAPFFHHACARYIGATEPLCFLNLGGVGNVTYVDPRKA
HCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCC
RPEDEGALLAFDTGPANAPINDFLQSRLGLAMDEGGRIASGGAVENGALELFLAEPYFAR
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCEECCCCEEECCCCCCCCCEEEEEECCHHHC
MPPKSLDRNDFPEMIGLVTELSDADATATLTAMCAAAVAQGMEHCPKAPSKVLVTGGGRH
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
NPVLMEMLRVSLDCPVEPVETVGLDGDMLEAQAFAYLAVRVARGLPTSAPSTTGVRACVG
CHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
GGTVTVPEGWTARKT
CCEEECCCCCCCCCC
>Mature Secondary Structure 
GRAISKSGPVRALGAMSGTSLDGVDVAVLETDGRDILGFGETGYRAYSDAEREVLRAAL
CCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHH
GQWTGDAVAAAARVVEAAHIEVMTDHADVDLIGFHGQTVAHAPRLQGTLQVGDGGVLAEA
CCCCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCHHCCCCCCEEEEECCCCHHHHH
LGRPVVWDFRSDDVSMGGEGAPLAPFFHHACARYIGATEPLCFLNLGGVGNVTYVDPRKA
HCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCC
RPEDEGALLAFDTGPANAPINDFLQSRLGLAMDEGGRIASGGAVENGALELFLAEPYFAR
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCEECCCCEEECCCCCCCCCEEEEEECCHHHC
MPPKSLDRNDFPEMIGLVTELSDADATATLTAMCAAAVAQGMEHCPKAPSKVLVTGGGRH
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
NPVLMEMLRVSLDCPVEPVETVGLDGDMLEAQAFAYLAVRVARGLPTSAPSTTGVRACVG
CHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
GGTVTVPEGWTARKT
CCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA