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The map label for this gene is lrp [C]

Identifier: 99080751

GI number: 99080751

Start: 971071

End: 971610

Strand: Direct

Name: lrp [C]

Synonym: TM1040_0910

Alternate gene names: 99080751

Gene position: 971071-971610 (Clockwise)

Preceding gene: 99080749

Following gene: 99080759

Centisome position: 30.34

GC content: 58.15

Gene sequence:

>540_bases
ATGAAAGGCCACGGTATGGAAAAAACAGAGACCATTCGGAGCTCCGCGCGGGCGAGCCGTGGTATTGATGCATTGGACCG
AAGAATATTAGGTGCGCTCAGCCGGGATGCCACCCAATCCTATGCCACGATCAGTGAACAGGTCGGGCTCTCGGCACCGG
CGGTGCATGAACGTGTGAAACGTCTTCGGGCCTCTGGGGCGATCAAGGCCACCGTCGCACAGATCGACGGCGCGCAAGTG
GGAAAGCCGATCCTCGCCTTTATCCATGTCGACACCATTGGCTGGGGTAAAACCCGCGAGATCATGGCGCTCGAAGAGTT
TCCCGAGGTGGAGGAAATCCACTCCACCACCGGCAATACCTGTCTCATAATGAAGGTGCGTGTGGCCAGCCCACATGCGC
TCGAGGGGCTCTTGTTCAAGATCTACGATATCGAAGGCGTGCGTGGCACCAGCACGTATCTGACGCTTTCGACGGTGCTT
GAACGCTCTGCGCAAGCGGATGTCACCGCCGATCTTGAAAGTGTCAGCTACCCGCGCTGA

Upstream 100 bases:

>100_bases
ATCCAGAGCGGTGGGGCAGAAGAGGGCATGACAGGTCTCGTGAGGGATTGAATTTCATTCGGCAGTTCGGCCTAATTGGT
GAAACTCATTCTGTGAAGAT

Downstream 100 bases:

>100_bases
CCCATTGTCAGCTGGGGCTGCGGAAATGTTTCGAGAGTTTCAGCCCCTGGCCCTGATAGTTTGAGGCAATCCCCGCGCCA
TAGAGCTGCTCTGGCAGCTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKGHGMEKTETIRSSARASRGIDALDRRILGALSRDATQSYATISEQVGLSAPAVHERVKRLRASGAIKATVAQIDGAQV
GKPILAFIHVDTIGWGKTREIMALEEFPEVEEIHSTTGNTCLIMKVRVASPHALEGLLFKIYDIEGVRGTSTYLTLSTVL
ERSAQADVTADLESVSYPR

Sequences:

>Translated_179_residues
MKGHGMEKTETIRSSARASRGIDALDRRILGALSRDATQSYATISEQVGLSAPAVHERVKRLRASGAIKATVAQIDGAQV
GKPILAFIHVDTIGWGKTREIMALEEFPEVEEIHSTTGNTCLIMKVRVASPHALEGLLFKIYDIEGVRGTSTYLTLSTVL
ERSAQADVTADLESVSYPR
>Mature_179_residues
MKGHGMEKTETIRSSARASRGIDALDRRILGALSRDATQSYATISEQVGLSAPAVHERVKRLRASGAIKATVAQIDGAQV
GKPILAFIHVDTIGWGKTREIMALEEFPEVEEIHSTTGNTCLIMKVRVASPHALEGLLFKIYDIEGVRGTSTYLTLSTVL
ERSAQADVTADLESVSYPR

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=28.7581699346405, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790182, Length=144, Percent_Identity=31.9444444444444, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 19406; Mature: 19406

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGHGMEKTETIRSSARASRGIDALDRRILGALSRDATQSYATISEQVGLSAPAVHERVK
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RLRASGAIKATVAQIDGAQVGKPILAFIHVDTIGWGKTREIMALEEFPEVEEIHSTTGNT
HHHHCCCCEEHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHEEHHHCCCHHHHHCCCCCE
CLIMKVRVASPHALEGLLFKIYDIEGVRGTSTYLTLSTVLERSAQADVTADLESVSYPR
EEEEEEEECCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKGHGMEKTETIRSSARASRGIDALDRRILGALSRDATQSYATISEQVGLSAPAVHERVK
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RLRASGAIKATVAQIDGAQVGKPILAFIHVDTIGWGKTREIMALEEFPEVEEIHSTTGNT
HHHHCCCCEEHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHEEHHHCCCHHHHHCCCCCE
CLIMKVRVASPHALEGLLFKIYDIEGVRGTSTYLTLSTVLERSAQADVTADLESVSYPR
EEEEEEEECCCHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA