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The map label for this gene is qmcA [H]

Identifier: 99080609

GI number: 99080609

Start: 822928

End: 823815

Strand: Reverse

Name: qmcA [H]

Synonym: TM1040_0768

Alternate gene names: 99080609

Gene position: 823815-822928 (Counterclockwise)

Preceding gene: 99080610

Following gene: 99080608

Centisome position: 25.74

GC content: 58.33

Gene sequence:

>888_bases
ATGACAGAACAAGACATCATCAACGCCCTTTCCGGTGGGCTTCTCTATATCGTGGCGGCGCTCTTTGTGATCCTGGTGAT
CCTCAAAGGCGTACGCATCGTGCCGCAATCGGAAAAATATGTGGTTGAGCGCTTTGGTCGCCTCAAATCCGTACTCGGCC
CCGGCATCAACTTTATCGTTCCATTTCTGGATGTTGTGCGCCACAAGGTCTCCATTCTGGAGCGCCAGTTGCCCAACGCC
AGCCAGGATGCGATCACCCGCGACAACGTGCTTGTGGAGATCGACACCTCGGTCTTTTACCGCATTCTTGAGCCTGAAAA
GACGGTATATCGCATTCGCGACGTGGATGGCGCCATCTCCACCACTGTTGCAGGCATCGTACGCGCCGAGATCGGCAAGA
TGGATCTCGATGAGGTGCAATCCAACCGCTCGCAGCTGATCGGTGAAATCAAGCGCAGCGTTGAAAGTGCCGTGGACGAC
TGGGGCATCGAAGTGACCCGCGCCGAAATCCTCGACGTGAACCTTGATCAGGCTACCCGCGATGCGATGCTGCAGCAACT
CAATGCCGAACGCGCCCGCCGCGCCCAGGTCACCGAGGCCGAGGGCAAGAAACGCGCAGTCGAGTTGGCGGCAGATGCTG
AGCTTTATGCTGCAGAGCAAACCGCCAAGGCACGCCGCATCGAAGCCGAGGCCGAGGCCTTCGCAACCCAGGTGGTCGCG
CAGGCGATTGCCGACAACGGTCTTTCGGCGGCCCAGTATCAGGTCGCTCTCAAGCAGGTTGAGGCGCTCAATGCGCTGGG
CAATGGCGATGGCAAACAGACCATCATCGTGCCTGCTCAGGCCATCGAGGCATTCGGTGACGCCTTCAAGATGCTAAAGG
CAAAGTGA

Upstream 100 bases:

>100_bases
CGCCGAATAGGCCATGCTACATCCCTGCGCCCTTTCCCCTTGACGCTCCGACGTTGAGGGGAAACCCTGCGCGCATCCTT
TTTAGTCGCGGAATTTTCCT

Downstream 100 bases:

>100_bases
TGGACGCTGTTTGGTCGCTGTGGTGGGTCTGGGGCGTGATCGCCCTCGGTCTCGCAATCGTCGAGATCCTCCTGCCCGGT
TTCATCTTTCTCGGGTTTGC

Product: SPFH domain-containing protein/band 7 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTEQDIINALSGGLLYIVAALFVILVILKGVRIVPQSEKYVVERFGRLKSVLGPGINFIVPFLDVVRHKVSILERQLPNA
SQDAITRDNVLVEIDTSVFYRILEPEKTVYRIRDVDGAISTTVAGIVRAEIGKMDLDEVQSNRSQLIGEIKRSVESAVDD
WGIEVTRAEILDVNLDQATRDAMLQQLNAERARRAQVTEAEGKKRAVELAADAELYAAEQTAKARRIEAEAEAFATQVVA
QAIADNGLSAAQYQVALKQVEALNALGNGDGKQTIIVPAQAIEAFGDAFKMLKAK

Sequences:

>Translated_295_residues
MTEQDIINALSGGLLYIVAALFVILVILKGVRIVPQSEKYVVERFGRLKSVLGPGINFIVPFLDVVRHKVSILERQLPNA
SQDAITRDNVLVEIDTSVFYRILEPEKTVYRIRDVDGAISTTVAGIVRAEIGKMDLDEVQSNRSQLIGEIKRSVESAVDD
WGIEVTRAEILDVNLDQATRDAMLQQLNAERARRAQVTEAEGKKRAVELAADAELYAAEQTAKARRIEAEAEAFATQVVA
QAIADNGLSAAQYQVALKQVEALNALGNGDGKQTIIVPAQAIEAFGDAFKMLKAK
>Mature_294_residues
TEQDIINALSGGLLYIVAALFVILVILKGVRIVPQSEKYVVERFGRLKSVLGPGINFIVPFLDVVRHKVSILERQLPNAS
QDAITRDNVLVEIDTSVFYRILEPEKTVYRIRDVDGAISTTVAGIVRAEIGKMDLDEVQSNRSQLIGEIKRSVESAVDDW
GIEVTRAEILDVNLDQATRDAMLQQLNAERARRAQVTEAEGKKRAVELAADAELYAAEQTAKARRIEAEAEAFATQVVAQ
AIADNGLSAAQYQVALKQVEALNALGNGDGKQTIIVPAQAIEAFGDAFKMLKAK

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=280, Percent_Identity=35.3571428571429, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI221316744, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI21686995, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI38016911, Length=219, Percent_Identity=27.8538812785388, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20149563, Length=276, Percent_Identity=21.7391304347826, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7657615, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786697, Length=286, Percent_Identity=36.3636363636364, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1790616, Length=220, Percent_Identity=26.8181818181818, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32564147, Length=268, Percent_Identity=32.089552238806, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17569493, Length=192, Percent_Identity=29.6875, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193209764, Length=195, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17569497, Length=208, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71987621, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71987612, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25153583, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17569499, Length=217, Percent_Identity=27.6497695852535, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193210507, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17570161, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32566490, Length=212, Percent_Identity=28.7735849056604, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17542664, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17570459, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71989948, Length=181, Percent_Identity=27.0718232044199, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71989955, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550506, Length=202, Percent_Identity=38.1188118811881, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18860517, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45556022, Length=199, Percent_Identity=30.6532663316583, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281361631, Length=195, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281361633, Length=195, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356845, Length=191, Percent_Identity=26.1780104712042, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573263, Length=212, Percent_Identity=26.4150943396226, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24657857, Length=202, Percent_Identity=30.1980198019802, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484448, Length=202, Percent_Identity=30.1980198019802, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281365664, Length=204, Percent_Identity=29.9019607843137, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62484274, Length=202, Percent_Identity=30.1980198019802, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 32256; Mature: 32125

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQDIINALSGGLLYIVAALFVILVILKGVRIVPQSEKYVVERFGRLKSVLGPGINFIV
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHH
PFLDVVRHKVSILERQLPNASQDAITRDNVLVEIDTSVFYRILEPEKTVYRIRDVDGAIS
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECHHHHHHHHCCHHHHHHHHHCCHHHH
TTVAGIVRAEIGKMDLDEVQSNRSQLIGEIKRSVESAVDDWGIEVTRAEILDVNLDQATR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHEECCCCHHHH
DAMLQQLNAERARRAQVTEAEGKKRAVELAADAELYAAEQTAKARRIEAEAEAFATQVVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAIADNGLSAAQYQVALKQVEALNALGNGDGKQTIIVPAQAIEAFGDAFKMLKAK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEQDIINALSGGLLYIVAALFVILVILKGVRIVPQSEKYVVERFGRLKSVLGPGINFIV
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHH
PFLDVVRHKVSILERQLPNASQDAITRDNVLVEIDTSVFYRILEPEKTVYRIRDVDGAIS
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECHHHHHHHHCCHHHHHHHHHCCHHHH
TTVAGIVRAEIGKMDLDEVQSNRSQLIGEIKRSVESAVDDWGIEVTRAEILDVNLDQATR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHEECCCCHHHH
DAMLQQLNAERARRAQVTEAEGKKRAVELAADAELYAAEQTAKARRIEAEAEAFATQVVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAIADNGLSAAQYQVALKQVEALNALGNGDGKQTIIVPAQAIEAFGDAFKMLKAK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]