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The map label for this gene is lipB [H]

Identifier: 94985686

GI number: 94985686

Start: 1687626

End: 1688429

Strand: Reverse

Name: lipB [H]

Synonym: Dgeo_1586

Alternate gene names: 94985686

Gene position: 1688429-1687626 (Counterclockwise)

Preceding gene: 94985687

Following gene: 94985685

Centisome position: 68.43

GC content: 69.65

Gene sequence:

>804_bases
TTGAACGGCACGCTCACCTTTTTGGGCAGCGCCGACAGCAAGGGCGTCCCGCGCTTCTGGTGTGACTGCCCGGTCTGTGC
TGAGGCCCGCACGAGCGGCGTCAACCGCCGTACTCGCAGCGCAGCGCTCGTGCGGGGAGCGGAGCCGTCGACCGGAGAGC
TGCAGACGCTCCTGCTCGACTGCGGCCCTGACCTGCACGCCCAACTTGCGCGGCTGCCGGGGCCGCTGGTGCCGGACGCG
GTGCTGATCTCACACGCGCACAACGATCACGTATTGGGCCTGGGCGACCTGCTGGACTATGTCGGCTACGCGGGCGAGCG
GCTGCACGTCTACGCTCCTGCCGCGGTCATCCCCGACATTCAGGACCGCTTTCGCTACGCCTTCCGCTCCGCGGCGCCCG
TGTGGCCTCTTCCGGAAGAAGGGCTGGAGGTGGCGGGCCTGCGCGTCCGCGCCTTCCGCGTGCCGCATGGGGCGAACGGC
CACAGCCACGCCTTCCGCCTAGACCGCCCCGGATTTGCGGCGGCCTACGTGACCGATGCCATCGACATCCCCGCAGAGGT
GATCGGGAGGTGGCTGACGAACCTGGACCTGCTGATTCTGGGCACGTCCTTTGCCGACGAGTCCAGGGTGCCTCACGCGG
GCCGCAGCGTGTACGACGTGCGCGAGGCCCTGGCCCTGCCCTGGGCGCAGGCGGTCCGGCGAGTCTTCCTGACCCATCTC
TCGCACGACGTGGACGTGCGCACACGGCCCCTGCCCCGGAATTGGAGCTGGGCACACGATGGGCTGGAGCTTCCTCTCGG
CTGA

Upstream 100 bases:

>100_bases
ACCTGGAGAGCGTGCGTGACCTGGCAGACGCCGTGCTGGTCGGCACCAGTCTGGCCGCCAGCGGCGACCTGACCCGCGCC
GCGCGCGAGCTGATGACCCC

Downstream 100 bases:

>100_bases
GGCTCGCCCCTGGCATTAGACTGCCCGCGATGTTGCCCGGCCTGTACCTGCTGCTGACGCTTCTTTTCGCCGCGGTCCTG
CTCGCGCTGCTGTGGCGGCC

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNGTLTFLGSADSKGVPRFWCDCPVCAEARTSGVNRRTRSAALVRGAEPSTGELQTLLLDCGPDLHAQLARLPGPLVPDA
VLISHAHNDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDIQDRFRYAFRSAAPVWPLPEEGLEVAGLRVRAFRVPHGANG
HSHAFRLDRPGFAAAYVTDAIDIPAEVIGRWLTNLDLLILGTSFADESRVPHAGRSVYDVREALALPWAQAVRRVFLTHL
SHDVDVRTRPLPRNWSWAHDGLELPLG

Sequences:

>Translated_267_residues
MNGTLTFLGSADSKGVPRFWCDCPVCAEARTSGVNRRTRSAALVRGAEPSTGELQTLLLDCGPDLHAQLARLPGPLVPDA
VLISHAHNDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDIQDRFRYAFRSAAPVWPLPEEGLEVAGLRVRAFRVPHGANG
HSHAFRLDRPGFAAAYVTDAIDIPAEVIGRWLTNLDLLILGTSFADESRVPHAGRSVYDVREALALPWAQAVRRVFLTHL
SHDVDVRTRPLPRNWSWAHDGLELPLG
>Mature_267_residues
MNGTLTFLGSADSKGVPRFWCDCPVCAEARTSGVNRRTRSAALVRGAEPSTGELQTLLLDCGPDLHAQLARLPGPLVPDA
VLISHAHNDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDIQDRFRYAFRSAAPVWPLPEEGLEVAGLRVRAFRVPHGANG
HSHAFRLDRPGFAAAYVTDAIDIPAEVIGRWLTNLDLLILGTSFADESRVPHAGRSVYDVREALALPWAQAVRRVFLTHL
SHDVDVRTRPLPRNWSWAHDGLELPLG

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29172; Mature: 29172

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTLTFLGSADSKGVPRFWCDCPVCAEARTSGVNRRTRSAALVRGAEPSTGELQTLLLD
CCCEEEEEECCCCCCCCCEECCCCCHHHHHHCCCCHHHHHHHHEECCCCCCCHHEEEEEC
CGPDLHAQLARLPGPLVPDAVLISHAHNDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDI
CCCCHHHHHHHCCCCCCCCHHEEECCCCCCEEEHHHHHHHHCCCCCEEEEEECHHHCCCH
QDRFRYAFRSAAPVWPLPEEGLEVAGLRVRAFRVPHGANGHSHAFRLDRPGFAAAYVTDA
HHHHHHHHHCCCCCCCCCCCCCEECCEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHH
IDIPAEVIGRWLTNLDLLILGTSFADESRVPHAGRSVYDVREALALPWAQAVRRVFLTHL
HCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
SHDVDVRTRPLPRNWSWAHDGLELPLG
CCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGTLTFLGSADSKGVPRFWCDCPVCAEARTSGVNRRTRSAALVRGAEPSTGELQTLLLD
CCCEEEEEECCCCCCCCCEECCCCCHHHHHHCCCCHHHHHHHHEECCCCCCCHHEEEEEC
CGPDLHAQLARLPGPLVPDAVLISHAHNDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDI
CCCCHHHHHHHCCCCCCCCHHEEECCCCCCEEEHHHHHHHHCCCCCEEEEEECHHHCCCH
QDRFRYAFRSAAPVWPLPEEGLEVAGLRVRAFRVPHGANGHSHAFRLDRPGFAAAYVTDA
HHHHHHHHHCCCCCCCCCCCCCEECCEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHH
IDIPAEVIGRWLTNLDLLILGTSFADESRVPHAGRSVYDVREALALPWAQAVRRVFLTHL
HCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
SHDVDVRTRPLPRNWSWAHDGLELPLG
CCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]