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The map label for this gene is oxaA [H]

Identifier: 94985665

GI number: 94985665

Start: 1665833

End: 1667413

Strand: Reverse

Name: oxaA [H]

Synonym: Dgeo_1565

Alternate gene names: 94985665

Gene position: 1667413-1665833 (Counterclockwise)

Preceding gene: 94985666

Following gene: 94985659

Centisome position: 67.58

GC content: 61.04

Gene sequence:

>1581_bases
ATGAAGATCAGAACCCTGCTTCCCCTGACGGCCCTCGGGGCGCTGCTCCTCACTGGATGCGGCACCACTGGCCCCCTTCC
GACCTTTGGCAAGGCCATTACGCCAGAGTGGATTCGTGCGGACTTTGACGGTCAACCCGGCGACGAGTACATCGCCACCA
GCAACCTTCAGGACGTGGTCTTCAATGCCCGCGGCGAGGTGATTGGCTGGTACGTCAAAAGCTACGCAGGCACGCCCTTC
ATCAAGAAACGCGCCGATGGCACCTATGACTTCAGTGCCCTGAAGAACACCAAGACCATTGTGAATATGGTCGGGGACCG
CAAGGCACTGGCGGTGACGGCGGAGGGCGTCCTCGACCCCGCTCAACCTGCTCAGACAGCCGCGCCGCAGCTCACCCAAA
ATCTGGCCCAGAACCGCCAGGAGGCCGTTTTCCGCTATACGCAAAACGGCGCGACCGTCACCAAAACCGTCGTTCTGCAC
CCGCGCAACTTCAAGGTGGACGTGCAAACGACGGTTGAGGGCGGCCCGCAGACCTACACCATGCTGTTTCCCGGTCTGGG
CAAGGCCGATAATCCCAGTGTCAAGGCCGTGCCGGTCGGGGGACAGCCCGCGACCGTACAGGGCAGTGGCACCCTCACCG
TACCGAACATCCAGTACGCCGCGCTGCAGGAAAAACCCAGCCAAATCGCGCACGCCTTGATCGTGCGGCCTCAGGCGGGC
ACGACCGCCAACGCCACCCTGACTGGGGGCGAGCAGGGATTGATCGCCGTGCACCTCAGCGGTCCCAGCAGTCTAGAAGT
CTACGGCGGCAAGAACGAACTCGTTCACCTGTACCAGAGTGGCTACCTGAACCTCCCTGGCCTCTTCCAACCCAACTTCT
TCGGCCAGATCAGCCTCCTGATCGTGAAGCTGATGGAAGGGCTGTACAAGTTGGTTGGCAACTGGGGCCTGGTGATTGTG
CTGCTGACCATTCTCTTGAGGCTGATCATGTGGCCGCTGATGCAGGCGCAGGGCCGCACAACCGCTCGCATGCAGGTGAT
GCAGCCCAAGATCAAGGAGATTCAGGACAAGTACAAGGACAAGCGCGACATCGAATCCCAGCGGGCCATGCAGATGGAGA
TGGCGCAGCTCTACCGGGAACACAACTTCAACCCGGCTGGGTGCTTCTCCACCTTCCTGCCCTTCCCCGTGCTGATCGCG
CTGTGGTCCACCATCCGCAACTTTGAGTTCGATTCGGGCTTCCTGTGGCTCCCTGACCTGGCGGTGCCCGATCCCTTCTA
CATCCTGGCGCTGATCTACCTGTGCGTGAACATCGGGCAGCTCTACGTGATGACCCGCAAGAACCCGGACATGTTCCGCC
AGCAGGCCTTTATTTACATCATCTTCCTGTACTTTGCCCTGACCTTCCCGGCCGGCGTGACGATCTACATCATCCTCTCG
ACCCTGATCGGCATCGGTCAGCAGATCCTGATCAACAGGCAGGTCGAGCGCGAGACGGCCAGCATCGGCCAGACGGTGCA
GAAGGCCCCTGCCCGGCTAGGGGGCAAGGCCGTCAAGACCATCGAGGCGCCCAAAAAGTAA

Upstream 100 bases:

>100_bases
GCTGCAATCCCCTGGTGCCGGGTGGCTGTGACCCCGTGCCGGAACACTTTCCCAGCTGGCGCGGCCCGCACCCCAAGACT
CCCTCCAGAAAGACACCCGA

Downstream 100 bases:

>100_bases
GTGTCAGTGCCGGAAGTATCAGTGCCGGAAGTAAAAGTAAAGGCCGCCCTGCCCCGTGAGGTGGGGCGGTTTTTTTGGGC
AGGTGCTGCGAGGACAGGCG

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKIRTLLPLTALGALLLTGCGTTGPLPTFGKAITPEWIRADFDGQPGDEYIATSNLQDVVFNARGEVIGWYVKSYAGTPF
IKKRADGTYDFSALKNTKTIVNMVGDRKALAVTAEGVLDPAQPAQTAAPQLTQNLAQNRQEAVFRYTQNGATVTKTVVLH
PRNFKVDVQTTVEGGPQTYTMLFPGLGKADNPSVKAVPVGGQPATVQGSGTLTVPNIQYAALQEKPSQIAHALIVRPQAG
TTANATLTGGEQGLIAVHLSGPSSLEVYGGKNELVHLYQSGYLNLPGLFQPNFFGQISLLIVKLMEGLYKLVGNWGLVIV
LLTILLRLIMWPLMQAQGRTTARMQVMQPKIKEIQDKYKDKRDIESQRAMQMEMAQLYREHNFNPAGCFSTFLPFPVLIA
LWSTIRNFEFDSGFLWLPDLAVPDPFYILALIYLCVNIGQLYVMTRKNPDMFRQQAFIYIIFLYFALTFPAGVTIYIILS
TLIGIGQQILINRQVERETASIGQTVQKAPARLGGKAVKTIEAPKK

Sequences:

>Translated_526_residues
MKIRTLLPLTALGALLLTGCGTTGPLPTFGKAITPEWIRADFDGQPGDEYIATSNLQDVVFNARGEVIGWYVKSYAGTPF
IKKRADGTYDFSALKNTKTIVNMVGDRKALAVTAEGVLDPAQPAQTAAPQLTQNLAQNRQEAVFRYTQNGATVTKTVVLH
PRNFKVDVQTTVEGGPQTYTMLFPGLGKADNPSVKAVPVGGQPATVQGSGTLTVPNIQYAALQEKPSQIAHALIVRPQAG
TTANATLTGGEQGLIAVHLSGPSSLEVYGGKNELVHLYQSGYLNLPGLFQPNFFGQISLLIVKLMEGLYKLVGNWGLVIV
LLTILLRLIMWPLMQAQGRTTARMQVMQPKIKEIQDKYKDKRDIESQRAMQMEMAQLYREHNFNPAGCFSTFLPFPVLIA
LWSTIRNFEFDSGFLWLPDLAVPDPFYILALIYLCVNIGQLYVMTRKNPDMFRQQAFIYIIFLYFALTFPAGVTIYIILS
TLIGIGQQILINRQVERETASIGQTVQKAPARLGGKAVKTIEAPKK
>Mature_526_residues
MKIRTLLPLTALGALLLTGCGTTGPLPTFGKAITPEWIRADFDGQPGDEYIATSNLQDVVFNARGEVIGWYVKSYAGTPF
IKKRADGTYDFSALKNTKTIVNMVGDRKALAVTAEGVLDPAQPAQTAAPQLTQNLAQNRQEAVFRYTQNGATVTKTVVLH
PRNFKVDVQTTVEGGPQTYTMLFPGLGKADNPSVKAVPVGGQPATVQGSGTLTVPNIQYAALQEKPSQIAHALIVRPQAG
TTANATLTGGEQGLIAVHLSGPSSLEVYGGKNELVHLYQSGYLNLPGLFQPNFFGQISLLIVKLMEGLYKLVGNWGLVIV
LLTILLRLIMWPLMQAQGRTTARMQVMQPKIKEIQDKYKDKRDIESQRAMQMEMAQLYREHNFNPAGCFSTFLPFPVLIA
LWSTIRNFEFDSGFLWLPDLAVPDPFYILALIYLCVNIGQLYVMTRKNPDMFRQQAFIYIIFLYFALTFPAGVTIYIILS
TLIGIGQQILINRQVERETASIGQTVQKAPARLGGKAVKTIEAPKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=211, Percent_Identity=34.1232227488152, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24662345, Length=222, Percent_Identity=29.2792792792793, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356443, Length=222, Percent_Identity=29.2792792792793, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 57830; Mature: 57830

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRTLLPLTALGALLLTGCGTTGPLPTFGKAITPEWIRADFDGQPGDEYIATSNLQDVV
CCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCHHHHH
FNARGEVIGWYVKSYAGTPFIKKRADGTYDFSALKNTKTIVNMVGDRKALAVTAEGVLDP
HCCCCCEEEHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AQPAQTAAPQLTQNLAQNRQEAVFRYTQNGATVTKTVVLHPRNFKVDVQTTVEGGPQTYT
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEECCCCEEEEEEEEECCCCEEEE
MLFPGLGKADNPSVKAVPVGGQPATVQGSGTLTVPNIQYAALQEKPSQIAHALIVRPQAG
EEECCCCCCCCCCEEEEECCCCCCEEECCCCEEECCCCHHHHHCCHHHHHHHHEECCCCC
TTANATLTGGEQGLIAVHLSGPSSLEVYGGKNELVHLYQSGYLNLPGLFQPNFFGQISLL
CCCCEEEECCCCCEEEEEECCCCCEEEECCCHHEEEEECCCCCCCCCCCCCCCHHHHHHH
IVKLMEGLYKLVGNWGLVIVLLTILLRLIMWPLMQAQGRTTARMQVMQPKIKEIQDKYKD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KRDIESQRAMQMEMAQLYREHNFNPAGCFSTFLPFPVLIALWSTIRNFEFDSGFLWLPDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
AVPDPFYILALIYLCVNIGQLYVMTRKNPDMFRQQAFIYIIFLYFALTFPAGVTIYIILS
CCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLIGIGQQILINRQVERETASIGQTVQKAPARLGGKAVKTIEAPKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCC
>Mature Secondary Structure
MKIRTLLPLTALGALLLTGCGTTGPLPTFGKAITPEWIRADFDGQPGDEYIATSNLQDVV
CCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCHHHHH
FNARGEVIGWYVKSYAGTPFIKKRADGTYDFSALKNTKTIVNMVGDRKALAVTAEGVLDP
HCCCCCEEEHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AQPAQTAAPQLTQNLAQNRQEAVFRYTQNGATVTKTVVLHPRNFKVDVQTTVEGGPQTYT
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEECCCCEEEEEEEEECCCCEEEE
MLFPGLGKADNPSVKAVPVGGQPATVQGSGTLTVPNIQYAALQEKPSQIAHALIVRPQAG
EEECCCCCCCCCCEEEEECCCCCCEEECCCCEEECCCCHHHHHCCHHHHHHHHEECCCCC
TTANATLTGGEQGLIAVHLSGPSSLEVYGGKNELVHLYQSGYLNLPGLFQPNFFGQISLL
CCCCEEEECCCCCEEEEEECCCCCEEEECCCHHEEEEECCCCCCCCCCCCCCCHHHHHHH
IVKLMEGLYKLVGNWGLVIVLLTILLRLIMWPLMQAQGRTTARMQVMQPKIKEIQDKYKD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KRDIESQRAMQMEMAQLYREHNFNPAGCFSTFLPFPVLIALWSTIRNFEFDSGFLWLPDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
AVPDPFYILALIYLCVNIGQLYVMTRKNPDMFRQQAFIYIIFLYFALTFPAGVTIYIILS
CCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLIGIGQQILINRQVERETASIGQTVQKAPARLGGKAVKTIEAPKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]