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The map label for this gene is 94985520

Identifier: 94985520

GI number: 94985520

Start: 1507323

End: 1508243

Strand: Reverse

Name: 94985520

Synonym: Dgeo_1420

Alternate gene names: NA

Gene position: 1508243-1507323 (Counterclockwise)

Preceding gene: 94985522

Following gene: 94985519

Centisome position: 61.13

GC content: 70.14

Gene sequence:

>921_bases
GTGCCGGTGAGTGCCTCCACTCCCTTTCTCCACCCCTTCCGGGCCTACACGCCTGCTGCGTACACCTTCCCGCTGCCCGA
GGGCCACCGCTTCCCGGCCTACAAGTACGCGGGGGTCGCGGAGCGTCTGGGAGGTTTGCTGCCCGTGCTGGAGACGCCCG
CCCTGACCTGGGCCGACGCGGCGCGCGTCCACGACCCGCTGTGGCTGCGGCGCTGGCGGCGCGGAGAGATCACGGCGGGC
GAAGAACGCGCCTTCGGACTGCCCTGGAGTGCCGGCGTGGTCGAACGGGCGCGGCGCGCGGCTGGCGGCAGCCTGGCGGC
CCTGCACGACGCGCTCGCCCAGGGCTGGGGCGCGAACCTGGCGGGCGGCACCCATCACGCCTTCCGGGACCGTGCCGAGG
GCTTTTGCCTGGTGAATGACGCCGCGATTCTGACCCACCTGGCGCTTGACGAGGGTCTGGCGCGGCGGGTGGCAATTCTG
GATCTGGACGTGCATCAGGGGAACGGCACGGCAGCGCTCCTGGCAGGGGAGGAACGGGCCCTGACCCTCAGCATTCACGG
TGAGCGCAACTACCCCTTTCGCAAGGAGACGAGCAGCCTGGATCTGGGCCTGCCGGATGGGGTGACCGATGCAGAGTACC
TGCGTGTGCTGCAGGACGAAGCCTTGCCTGTCCTGGACGCTTTTCGCCCCGACCTGCTGCTGTACCTCGCGGGCGTGGAC
GTGCTGGCGGGGGACCGTTTCGGCCGCTTTGCGCTGACCCTCGCGGGGGTGCGTGAACGCAACCGCAGGGTGCTGAGGTG
GGCCCGGGAGGCCGGCGTGCCGGTCGTGACCATGTTGGCGGGTGGATATAACCGCGATCACGCCCTCACCGTGGAGGCGC
ACGCGAGTGTGGTGGAGGACGGGTTGGAGGTGTTCTCCTAA

Upstream 100 bases:

>100_bases
GATAGCCTAAGCCCTGCTTGGCTCCGCCGCCTCGTTCAAGCTTTTGAGTTCAAGCTTTGAAGTCCCTCGCCCGGTTTTCT
TTCGCCGCCTGCGCCAGACT

Downstream 100 bases:

>100_bases
AAAGGCTTGGGGAGACCTTTACAAAGTGTGTGTTGAACGCTTGGCGGGTCTGGACGCCTTGTACAGTCACGACAGCTGTC
GTTGGCCCGCGTTCCCTCGG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPVSASTPFLHPFRAYTPAAYTFPLPEGHRFPAYKYAGVAERLGGLLPVLETPALTWADAARVHDPLWLRRWRRGEITAG
EERAFGLPWSAGVVERARRAAGGSLAALHDALAQGWGANLAGGTHHAFRDRAEGFCLVNDAAILTHLALDEGLARRVAIL
DLDVHQGNGTAALLAGEERALTLSIHGERNYPFRKETSSLDLGLPDGVTDAEYLRVLQDEALPVLDAFRPDLLLYLAGVD
VLAGDRFGRFALTLAGVRERNRRVLRWAREAGVPVVTMLAGGYNRDHALTVEAHASVVEDGLEVFS

Sequences:

>Translated_306_residues
MPVSASTPFLHPFRAYTPAAYTFPLPEGHRFPAYKYAGVAERLGGLLPVLETPALTWADAARVHDPLWLRRWRRGEITAG
EERAFGLPWSAGVVERARRAAGGSLAALHDALAQGWGANLAGGTHHAFRDRAEGFCLVNDAAILTHLALDEGLARRVAIL
DLDVHQGNGTAALLAGEERALTLSIHGERNYPFRKETSSLDLGLPDGVTDAEYLRVLQDEALPVLDAFRPDLLLYLAGVD
VLAGDRFGRFALTLAGVRERNRRVLRWAREAGVPVVTMLAGGYNRDHALTVEAHASVVEDGLEVFS
>Mature_305_residues
PVSASTPFLHPFRAYTPAAYTFPLPEGHRFPAYKYAGVAERLGGLLPVLETPALTWADAARVHDPLWLRRWRRGEITAGE
ERAFGLPWSAGVVERARRAAGGSLAALHDALAQGWGANLAGGTHHAFRDRAEGFCLVNDAAILTHLALDEGLARRVAILD
LDVHQGNGTAALLAGEERALTLSIHGERNYPFRKETSSLDLGLPDGVTDAEYLRVLQDEALPVLDAFRPDLLLYLAGVDV
LAGDRFGRFALTLAGVRERNRRVLRWAREAGVPVVTMLAGGYNRDHALTVEAHASVVEDGLEVFS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=204, Percent_Identity=32.3529411764706, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI209862883, Length=199, Percent_Identity=32.6633165829146, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13128860, Length=213, Percent_Identity=30.0469483568075, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI13128862, Length=214, Percent_Identity=29.4392523364486, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI8923769, Length=215, Percent_Identity=27.906976744186, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI293336691, Length=185, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI262073088, Length=172, Percent_Identity=28.4883720930233, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13128864, Length=207, Percent_Identity=32.3671497584541, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI17158039, Length=169, Percent_Identity=31.3609467455621, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30795204, Length=169, Percent_Identity=31.3609467455621, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI30795202, Length=169, Percent_Identity=31.3609467455621, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=252, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17537347, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561978, Length=234, Percent_Identity=30.3418803418803, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508561, Length=216, Percent_Identity=31.0185185185185, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534739, Length=269, Percent_Identity=26.7657992565056, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193206283, Length=209, Percent_Identity=29.6650717703349, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540332, Length=209, Percent_Identity=29.6650717703349, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540334, Length=209, Percent_Identity=29.6650717703349, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25154020, Length=168, Percent_Identity=32.7380952380952, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25154022, Length=232, Percent_Identity=29.3103448275862, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=213, Percent_Identity=27.6995305164319, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323999, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=177, Percent_Identity=28.8135593220339, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=178, Percent_Identity=28.6516853932584, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=275, Percent_Identity=26.1818181818182, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649807, Length=268, Percent_Identity=33.2089552238806, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644244, Length=179, Percent_Identity=32.4022346368715, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24657891, Length=210, Percent_Identity=29.5238095238095, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24642142, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642146, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642144, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360899, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33251; Mature: 33120

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSASTPFLHPFRAYTPAAYTFPLPEGHRFPAYKYAGVAERLGGLLPVLETPALTWADA
CCCCCCCCCCCCHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHH
ARVHDPLWLRRWRRGEITAGEERAFGLPWSAGVVERARRAAGGSLAALHDALAQGWGANL
HHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
AGGTHHAFRDRAEGFCLVNDAAILTHLALDEGLARRVAILDLDVHQGNGTAALLAGEERA
CCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCEE
LTLSIHGERNYPFRKETSSLDLGLPDGVTDAEYLRVLQDEALPVLDAFRPDLLLYLAGVD
EEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCHHHEEHHHCCC
VLAGDRFGRFALTLAGVRERNRRVLRWAREAGVPVVTMLAGGYNRDHALTVEAHASVVED
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHH
GLEVFS
HHHHCC
>Mature Secondary Structure 
PVSASTPFLHPFRAYTPAAYTFPLPEGHRFPAYKYAGVAERLGGLLPVLETPALTWADA
CCCCCCCCCCCHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHHH
ARVHDPLWLRRWRRGEITAGEERAFGLPWSAGVVERARRAAGGSLAALHDALAQGWGANL
HHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
AGGTHHAFRDRAEGFCLVNDAAILTHLALDEGLARRVAILDLDVHQGNGTAALLAGEERA
CCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCEE
LTLSIHGERNYPFRKETSSLDLGLPDGVTDAEYLRVLQDEALPVLDAFRPDLLLYLAGVD
EEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCHHHEEHHHCCC
VLAGDRFGRFALTLAGVRERNRRVLRWAREAGVPVVTMLAGGYNRDHALTVEAHASVVED
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHH
GLEVFS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]