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The map label for this gene is cobP [H]

Identifier: 94972336

GI number: 94972336

Start: 148763

End: 149317

Strand: Direct

Name: cobP [H]

Synonym: Dgeo_2873

Alternate gene names: 94972336

Gene position: 148763-149317 (Clockwise)

Preceding gene: 94972337

Following gene: 94972335

Centisome position: 25.91

GC content: 69.37

Gene sequence:

>555_bases
GTGATTGTGTTTGTGACCGGCGGCGCTCGCAGCGGCAAGAGCACGTTTGCCGAGCGCCGCGCTGCCGCCTCCGGCGAGGC
CGTCACCTACCTTGCCACCGCCCAGGCTTTTGACGCCGAGATGGCGGACAGAATCGCTCGCCACCGCGCGGACCGCCCGG
CGGAGTGGCTCACCCTGGAGGAGCCGCTCCATGTCCCAGAAGCGCTGGAGCGCGTCCCGACGCCCACCGTCTTGCTCGAC
TGCCTGAGTCTGTGGGTGAGCAACCTCTTGCTGGAGGGCCTCTCCGACCCCGCGGCCCTGGCCCGTGCTGACGCTCTGCT
CGCCGCCGCCCGCGCCCGCCCCGGCCTGACGGTCTTGGTCAGCAACGAGGTGGGCTTTGGGATTGTTCCCGAGAACGCCC
TGGCGCGCCGCTACCGAGACCTGCTGGGCTGGGTCAATCAGCGGGCTGCCGCCGCGAGCGACGAGGCTTGGTTGCTGGTC
AGTGGCCTGCCCCTTCAGCTCAAGCCCATGTCGTTCCCCCCTCATTCCCCCGCAAAGGAGCCTTATGCACCCTGA

Upstream 100 bases:

>100_bases
TCACGCCGCCCGTTCCGCTGGCCAGCCTGGACGCGCGACTCGACGCCATTGCTGAGCGCGTCCGGGTCAGCTTGGACTGG
GACTTTGTCCGGAGGCTCTT

Downstream 100 bases:

>100_bases
ACTGACTGCCTTGATGTCCGCCATCCGTCCCGCCGACGCCGCTGTCATGCAGGCTGCCCGCGAGCGCCAGGCCCAGCTCA
CCAAACCCGCCGGTGCACTG

Product: cobalbumin biosynthesis enzyme

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIVFVTGGARSGKSTFAERRAAASGEAVTYLATAQAFDAEMADRIARHRADRPAEWLTLEEPLHVPEALERVPTPTVLLD
CLSLWVSNLLLEGLSDPAALARADALLAAARARPGLTVLVSNEVGFGIVPENALARRYRDLLGWVNQRAAAASDEAWLLV
SGLPLQLKPMSFPPHSPAKEPYAP

Sequences:

>Translated_184_residues
MIVFVTGGARSGKSTFAERRAAASGEAVTYLATAQAFDAEMADRIARHRADRPAEWLTLEEPLHVPEALERVPTPTVLLD
CLSLWVSNLLLEGLSDPAALARADALLAAARARPGLTVLVSNEVGFGIVPENALARRYRDLLGWVNQRAAAASDEAWLLV
SGLPLQLKPMSFPPHSPAKEPYAP
>Mature_184_residues
MIVFVTGGARSGKSTFAERRAAASGEAVTYLATAQAFDAEMADRIARHRADRPAEWLTLEEPLHVPEALERVPTPTVLLD
CLSLWVSNLLLEGLSDPAALARADALLAAARARPGLTVLVSNEVGFGIVPENALARRYRDLLGWVNQRAAAASDEAWLLV
SGLPLQLKPMSFPPHSPAKEPYAP

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=45.6043956043956, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19774; Mature: 19774

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFVTGGARSGKSTFAERRAAASGEAVTYLATAQAFDAEMADRIARHRADRPAEWLTLE
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHEECC
EPLHVPEALERVPTPTVLLDCLSLWVSNLLLEGLSDPAALARADALLAAARARPGLTVLV
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEE
SNEVGFGIVPENALARRYRDLLGWVNQRAAAASDEAWLLVSGLPLQLKPMSFPPHSPAKE
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCCCCCC
PYAP
CCCC
>Mature Secondary Structure
MIVFVTGGARSGKSTFAERRAAASGEAVTYLATAQAFDAEMADRIARHRADRPAEWLTLE
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHEECC
EPLHVPEALERVPTPTVLLDCLSLWVSNLLLEGLSDPAALARADALLAAARARPGLTVLV
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEE
SNEVGFGIVPENALARRYRDLLGWVNQRAAAASDEAWLLVSGLPLQLKPMSFPPHSPAKE
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCCCCCC
PYAP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]