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The map label for this gene is cobT [H]

Identifier: 94972335

GI number: 94972335

Start: 149307

End: 150386

Strand: Direct

Name: cobT [H]

Synonym: Dgeo_2872

Alternate gene names: 94972335

Gene position: 149307-150386 (Clockwise)

Preceding gene: 94972336

Following gene: 94972333

Centisome position: 26.01

GC content: 70.93

Gene sequence:

>1080_bases
ATGCACCCTGAACTGACTGCCTTGATGTCCGCCATCCGTCCCGCCGACGCCGCTGTCATGCAGGCTGCCCGCGAGCGCCA
GGCCCAGCTCACCAAACCCGCCGGTGCACTGGGTGACCTTGAAGACCTGGCTGTGCGGCTCTCAGGCGTGTTCGGCCAAG
TGCAGCCCCACCCGCGCGGGGTGGCGGTGGTTGTGGCTGCGGGCGACCACGGGGTCGCGGCGGCGGGGGTGAGCGCCTAC
CCCCCCGAGGTCACGCCCGCGATGGTGGCCAACTTTCTGGCCGACACCCCCGCCGGGCCGGGCGGCGCTGCCGTGAATGC
GATTGCTCGGACCTTGGGCGCACGCGTGTACGTGATGGACGCAGGCGTCAATGCTGAGCTACCCGCTCATCCGCGCTTGG
TGCGGGCAGCGCTGCGGCGCGGTACCCGCGACCTGCGGACCGGTCCTGCCATGACCCGCTCAGAAACCGAGGCGCTGATG
CTGGCGGGGGCGGCCCTGGCGCGGCAAGCTATTCAGGAGGGCGCCGACCTGCTGGTTCCAGGTGAGATGGGCATCGGAAA
CACCACGCCCGCCGCCGCCATCACGGCCCGGATGCTGGGTCTCGACCCGGTGGCGGTGACGGGCCGGGGCACCGGTGTAG
ACGACGCGGCGCTGGAGCGCAAGGTGGCGGCGGTGCGGGCAGCCCTGGAGCGGGGAGACAGTGACCCGGCCGATCCCCTG
GGCGTTCTGGCCGATCTGGGCGGCTTTGAGATTGCAGCGATGCTGGGCATGATGCTTCAGACGGCTGCCCTGCGCCGAGC
GGTGATCCTCGACGGCTTCGTGGAGGGCGCAGCGGCCCTGGTAGGGGTTGCCCTCGTGCCTGAACTGCGCGACTTCCTGT
TTCCGGCGGGCGAATGCGCCGAGGTCGGCCACGCCGCGCAGCTCACGCATCTGCAGCTGAAACCAATGTTCCGCCTGGGC
CTGCGCCTGGGCGAGGGGACGGGCGGCCTGCTCGCTGCTCCCCTTCTTCTGGCTGCCGCCGCGACCCTGCGCGAGATGCG
GACCTTTGCGGAAGCTGGGGTGCCAGGGAGTACGGTGTAG

Upstream 100 bases:

>100_bases
GCTGCCGCCGCGAGCGACGAGGCTTGGTTGCTGGTCAGTGGCCTGCCCCTTCAGCTCAAGCCCATGTCGTTCCCCCCTCA
TTCCCCCGCAAAGGAGCCTT

Downstream 100 bases:

>100_bases
CTGGCACAGTGGCGTTGGCAGTGGAGTGGGCACGGTGGAGGTAAGGGGGTGGTGGAGCGCCACTCCTTGGGGCGGTCCAG
TATCCCGACCAGACCGCGCG

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MHPELTALMSAIRPADAAVMQAARERQAQLTKPAGALGDLEDLAVRLSGVFGQVQPHPRGVAVVVAAGDHGVAAAGVSAY
PPEVTPAMVANFLADTPAGPGGAAVNAIARTLGARVYVMDAGVNAELPAHPRLVRAALRRGTRDLRTGPAMTRSETEALM
LAGAALARQAIQEGADLLVPGEMGIGNTTPAAAITARMLGLDPVAVTGRGTGVDDAALERKVAAVRAALERGDSDPADPL
GVLADLGGFEIAAMLGMMLQTAALRRAVILDGFVEGAAALVGVALVPELRDFLFPAGECAEVGHAAQLTHLQLKPMFRLG
LRLGEGTGGLLAAPLLLAAAATLREMRTFAEAGVPGSTV

Sequences:

>Translated_359_residues
MHPELTALMSAIRPADAAVMQAARERQAQLTKPAGALGDLEDLAVRLSGVFGQVQPHPRGVAVVVAAGDHGVAAAGVSAY
PPEVTPAMVANFLADTPAGPGGAAVNAIARTLGARVYVMDAGVNAELPAHPRLVRAALRRGTRDLRTGPAMTRSETEALM
LAGAALARQAIQEGADLLVPGEMGIGNTTPAAAITARMLGLDPVAVTGRGTGVDDAALERKVAAVRAALERGDSDPADPL
GVLADLGGFEIAAMLGMMLQTAALRRAVILDGFVEGAAALVGVALVPELRDFLFPAGECAEVGHAAQLTHLQLKPMFRLG
LRLGEGTGGLLAAPLLLAAAATLREMRTFAEAGVPGSTV
>Mature_359_residues
MHPELTALMSAIRPADAAVMQAARERQAQLTKPAGALGDLEDLAVRLSGVFGQVQPHPRGVAVVVAAGDHGVAAAGVSAY
PPEVTPAMVANFLADTPAGPGGAAVNAIARTLGARVYVMDAGVNAELPAHPRLVRAALRRGTRDLRTGPAMTRSETEALM
LAGAALARQAIQEGADLLVPGEMGIGNTTPAAAITARMLGLDPVAVTGRGTGVDDAALERKVAAVRAALERGDSDPADPL
GVLADLGGFEIAAMLGMMLQTAALRRAVILDGFVEGAAALVGVALVPELRDFLFPAGECAEVGHAAQLTHLQLKPMFRLG
LRLGEGTGGLLAAPLLLAAAATLREMRTFAEAGVPGSTV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=357, Percent_Identity=36.1344537815126, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36468; Mature: 36468

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPELTALMSAIRPADAAVMQAARERQAQLTKPAGALGDLEDLAVRLSGVFGQVQPHPRG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
VAVVVAAGDHGVAAAGVSAYPPEVTPAMVANFLADTPAGPGGAAVNAIARTLGARVYVMD
EEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEE
AGVNAELPAHPRLVRAALRRGTRDLRTGPAMTRSETEALMLAGAALARQAIQEGADLLVP
CCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GEMGIGNTTPAAAITARMLGLDPVAVTGRGTGVDDAALERKVAAVRAALERGDSDPADPL
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
GVLADLGGFEIAAMLGMMLQTAALRRAVILDGFVEGAAALVGVALVPELRDFLFPAGECA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EVGHAAQLTHLQLKPMFRLGLRLGEGTGGLLAAPLLLAAAATLREMRTFAEAGVPGSTV
HHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHPELTALMSAIRPADAAVMQAARERQAQLTKPAGALGDLEDLAVRLSGVFGQVQPHPRG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
VAVVVAAGDHGVAAAGVSAYPPEVTPAMVANFLADTPAGPGGAAVNAIARTLGARVYVMD
EEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEE
AGVNAELPAHPRLVRAALRRGTRDLRTGPAMTRSETEALMLAGAALARQAIQEGADLLVP
CCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GEMGIGNTTPAAAITARMLGLDPVAVTGRGTGVDDAALERKVAAVRAALERGDSDPADPL
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
GVLADLGGFEIAAMLGMMLQTAALRRAVILDGFVEGAAALVGVALVPELRDFLFPAGECA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EVGHAAQLTHLQLKPMFRLGLRLGEGTGGLLAAPLLLAAAATLREMRTFAEAGVPGSTV
HHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]