| Definition | Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence. |
|---|---|
| Accession | NC_008010 |
| Length | 574,127 |
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The map label for this gene is gno [H]
Identifier: 94972328
GI number: 94972328
Start: 157234
End: 158001
Strand: Direct
Name: gno [H]
Synonym: Dgeo_2865
Alternate gene names: 94972328
Gene position: 157234-158001 (Clockwise)
Preceding gene: 94972329
Following gene: 94972327
Centisome position: 27.39
GC content: 69.53
Gene sequence:
>768_bases ATGACCTCAACTGCTCAGATGCCCCACATCCTTGACCTCTTTCGTCTCGACGGACGCCACGCCCTGGTGACTGGCGGCGC GCAGGGGATCGGCTTCGAGATCGCGCGCGGACTGGCCCAGGCTGGAGCGCGCGTGACCATCGCGGACCTGAACCCCGACG TGGGGGAGGGTGCGGCCCGCGAATTGGACGGGACCTTCGAGCGACTGAACGTCACCGACGCGGACGCCGTGGCGGACCTG GCCCGGCGCCTCCCCGATGTGGACGTGCTTGTGAACAACGCGGGAATTGTCCGCAACGCTCCCGCCGAGGACACCCCCGA TGACGACTGGCGGGCGGTGCTGAGCGTCAACCTGGACGGGGTGTTCTGGTGCTGCCGCGAGTTCGGCCGAACCATGCTGG CTAGAGGCCGCGGCGCCATCGTCAGCACCGCCAGCATGAGCGGCCTGATCAGCAATCATCCGCAGCCGCAGGCCGCCTAC AACGCCTCCAAGGCCGCGGTCATTCACCTCACCCGCAGCCTCGCGGGCGAGTGGGCGAGCCGGGGCGTGCGCGTGAACGC CGTCGCTCCCGGCTACACCGCTACACCCCTTACCCGGCGCGGTCTGGAGACGCCCGAGTGGCGCGAAACCTGGCTGAAGG AAACGCCGCTGGGCCGCCTCGCCGAACCCCGCGAGATTGCGCCCGCCGTGCTCTACCTCGCCAGCGACGCCGCCAGCTTC GTCACCGGGCATACGCTCGTGGTGGACGGTGGGTACACGGTGTGGTGA
Upstream 100 bases:
>100_bases GGGAAAGCCTGCGCCGCCAGGGTCCTCTGGGGGCCATGCGGGCGCTGATGGGTGAAGAGTCCTCCCCGAGCAACGTGACT TCTCTTTCAGGAAGGTGAAT
Downstream 100 bases:
>100_bases GGGTTTTCCCGATCAGAAAGGCAGGACGATGACTTCCCCGGATTCCTCTTTGTCTTCCCGCATCAGCGTTTTGCATGGCA TCCGCGACCTGCGCTGGGAG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MTSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAARELDGTFERLNVTDADAVADL ARRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDGVFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAY NASKAAVIHLTRSLAGEWASRGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASF VTGHTLVVDGGYTVW
Sequences:
>Translated_255_residues MTSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAARELDGTFERLNVTDADAVADL ARRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDGVFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAY NASKAAVIHLTRSLAGEWASRGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASF VTGHTLVVDGGYTVW >Mature_254_residues TSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAARELDGTFERLNVTDADAVADLA RRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDGVFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAYN ASKAAVIHLTRSLAGEWASRGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASFV TGHTLVVDGGYTVW
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=33.5907335907336, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=35.5932203389831, Blast_Score=128, Evalue=6e-30, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=33.4677419354839, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=33.0739299610895, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=34.8, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=33.4661354581673, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=34.9344978165939, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=33.7301587301587, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI31542939, Length=225, Percent_Identity=32.4444444444444, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.5490196078431, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=31.6, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=31.6582914572864, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI4504505, Length=241, Percent_Identity=30.7053941908714, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=30, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503301, Length=232, Percent_Identity=27.1551724137931, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=32.9479768786127, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI20149619, Length=262, Percent_Identity=27.8625954198473, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=33.1632653061224, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.9709543568465, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI142976729, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI150247226, Length=217, Percent_Identity=31.3364055299539, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=37.9446640316205, Blast_Score=157, Evalue=6e-40, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=38.4313725490196, Blast_Score=149, Evalue=2e-37, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=38.7755102040816, Blast_Score=148, Evalue=4e-37, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=33.7301587301587, Blast_Score=141, Evalue=5e-35, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=35.3174603174603, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=35.3658536585366, Blast_Score=127, Evalue=6e-31, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=37.1541501976285, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=35.3174603174603, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=30.6201550387597, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=34.2741935483871, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=31.7460317460317, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.9502074688797, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1787526, Length=247, Percent_Identity=28.7449392712551, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=39.2, Blast_Score=150, Evalue=6e-37, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=39.5918367346939, Blast_Score=147, Evalue=5e-36, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=33.596837944664, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=32.5301204819277, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=32.5670498084291, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=29.2134831460674, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.811320754717, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=33.2, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.8804780876494, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=29.6703296703297, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=29.5880149812734, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=29.6992481203008, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.0483870967742, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=32.03125, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=31.0861423220974, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=28.4644194756554, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=29.7397769516729, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=28.7313432835821, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=27.6752767527675, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.037037037037, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=32.1888412017167, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=29.2134831460674, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=29.5880149812734, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=29.3814432989691, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=26.0377358490566, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17568967, Length=239, Percent_Identity=28.0334728033473, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538486, Length=279, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.0676691729323, Blast_Score=69, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.2945736434109, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=28.5106382978723, Blast_Score=79, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6322067, Length=226, Percent_Identity=30.0884955752212, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6320089, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=33.0645161290323, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=35.0806451612903, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=35.9683794466403, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=37.1428571428571, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=32.9218106995885, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=35.0597609561753, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644337, Length=174, Percent_Identity=41.3793103448276, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=6e-22, Organism=Drosophila melanogaster, GI18859837, Length=240, Percent_Identity=32.9166666666667, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=33.596837944664, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI281364494, Length=238, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21356301, Length=235, Percent_Identity=30.6382978723404, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=31.2820512820513, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584748, Length=195, Percent_Identity=31.2820512820513, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=29.8507462686567, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24665243, Length=212, Percent_Identity=30.6603773584906, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI221331218, Length=212, Percent_Identity=30.6603773584906, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24640492, Length=237, Percent_Identity=25.3164556962025, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI221331216, Length=213, Percent_Identity=30.5164319248826, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24665247, Length=213, Percent_Identity=30.5164319248826, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI28574402, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584744, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648693, Length=239, Percent_Identity=30.5439330543933, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355889, Length=239, Percent_Identity=30.5439330543933, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27252; Mature: 27121
Theoretical pI: Translated: 5.34; Mature: 5.34
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAAR CCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHH ELDGTFERLNVTDADAVADLARRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDG HHCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCH VFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAYNASKAAVIHLTRSLAGEWAS HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHCCCCHHEEHHHHHHHHHHHH RGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASF CCEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH VTGHTLVVDGGYTVW HCCCEEEECCCEECC >Mature Secondary Structure TSTAQMPHILDLFRLDGRHALVTGGAQGIGFEIARGLAQAGARVTIADLNPDVGEGAAR CCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHH ELDGTFERLNVTDADAVADLARRLPDVDVLVNNAGIVRNAPAEDTPDDDWRAVLSVNLDG HHCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCH VFWCCREFGRTMLARGRGAIVSTASMSGLISNHPQPQAAYNASKAAVIHLTRSLAGEWAS HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHCCCCHHEEHHHHHHHHHHHH RGVRVNAVAPGYTATPLTRRGLETPEWRETWLKETPLGRLAEPREIAPAVLYLASDAASF CCEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH VTGHTLVVDGGYTVW HCCCEEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]