Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 94972326

GI number: 94972326

Start: 159099

End: 160616

Strand: Direct

Name: xylB [H]

Synonym: Dgeo_2863

Alternate gene names: 94972326

Gene position: 159099-160616 (Clockwise)

Preceding gene: 94972327

Following gene: 94972319

Centisome position: 27.71

GC content: 68.25

Gene sequence:

>1518_bases
ATGTCGGCTGAGCTGCTCATCGGGATCGACGTGGGCACATACTCCAGCAAGGGCGTGCTGGTGACGCTGGATGGCCAAAT
CCTGCGCCAGCACGTCATCCCCCACGGCATCAATCTGCCTGCACCTGGCCACGTCGAGCAGGACGCGGAAGAGGTGTGGT
GGGGCGATACGTTGGCCCTGCTGCGCGAGCTGTTAAAGGACCCGTATTCCGGAGCAGACGTGGCCGGCATTGCCCTGAGC
GCCATCGGCCCGACGCTGCTGCCGCTGGACGGGGCGGGGCGGCCCCTGCGTCCCGGCATTCTCTATGGGGTAGACACCCG
CGCGGGGGCGCAGATCGACGCGCTGAACCGTGAGATCGGCGAGGCGGCCATCTTGGCCCACAGCGGCATGTCCCTCACCA
GTCAGGCGATCGGCCCTAAGATCCGCTGGTTGCGCGAGCGCGAGCCGGAGGTGTGGGCGCAGACGCGGACACTCACCACC
GCGAGCAGCTACCTGACCTACCGCCTGACCGGCAGGCACGTGCTGGACCATCACACGGCAGCCCATTCCATGCCGCTCTA
CGATCCGCGCACCCGCGCGTGGACGGCGCAGTTTGCCCCAGCGGTACTGGGCGACGTCGGCTTGGACCGCCTGCCTGACC
TCGCCTGGAGTGACGAGCTGGCCGGGTACGTGACCGCAGAAGCTGCCGCCCAGACCGGCCTGCGCGAGGACACACCGGTC
GCGGTGGGCACGGTGGACGCACTCAGCGAGGCCGTCAGCGTGGGGGCGGTCCACCCCGGCGACCTGATGGTGATGTACGG
CTCCACCACCTTCTTCATCCTGGTGCAGGACACGCCTACGCCCGACCCGCGGGTCTGGACGGTGGGCGGCGCCTTTGCCG
GACAGGTCAACCTCGCCGCCGGGATGAGCACCACGGGCAGCCTGACCCGCTGGTTTGTGGACGAGCTGGCGCGGGAATAT
TCAACCGAGCAGGCGTATGACCGCCTGTTCGCAGAAGCGGCACACCTCGCTCCCGGCGCTGAGGGTCTCCTTCTCCTGCC
CTACTTCAGCGGCGAGCGGACCCCGATCAACGATCCGCAGGCACGGGGTGTGATCGCGGGCTTGACGCTGGCCCACACCC
GCGCCCACCTCTTCCGTGCCGCGCTGGAGGGCGTAGGCTACGGCATTCGGCAGAACATCGAAGCGTTTCGTGAGCTGGGA
GCGCAGGTGCGGCGGCTGGTGGCGGTCGGCGGCGGCGCGAAGGGGCGGACCTGGCTCCAGATTGTCAGCGACATCAGCGG
CGAGGTGCAGGAGTTGCCCGAGGTGACGGTCGGGGCGAGTTATGGGGATGCCTTTTTGGCCGGCCTCGCGGCGGGCGTGC
TGAGGCGTGACGACCTGAACCGCTGGGTGAGGATTGCGGACCGGGTTGATCCGAATCCCGCTCTCAAAGCGGACTATGAT
CGCCTGTACGGCCTCTACCGCGATCTCTACGCGCAGACCCGAGGGACGGTCCATGCCCTGAGCCGTCCCAGTGCCTGA

Upstream 100 bases:

>100_bases
CTCGACGTGCTTGTCACCCACCGCTATCCCTTTGACCAGACCCCCGAAGCTTTTGCGTTCGCTGACCGTGAGAAACGCGC
CAGCATGAAGGTCATGATCG

Downstream 100 bases:

>100_bases
GCGCCGCGCGGGAAGGACGCCCGGCGCCCGCGTCATCTCAGAAATTGACGGTACCAGTGGCCGCTGTCTTTGAGGACCCG
GGTCTGGGTGGGATAATCCA

Product: carbohydrate kinase, FGGY

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSAELLIGIDVGTYSSKGVLVTLDGQILRQHVIPHGINLPAPGHVEQDAEEVWWGDTLALLRELLKDPYSGADVAGIALS
AIGPTLLPLDGAGRPLRPGILYGVDTRAGAQIDALNREIGEAAILAHSGMSLTSQAIGPKIRWLREREPEVWAQTRTLTT
ASSYLTYRLTGRHVLDHHTAAHSMPLYDPRTRAWTAQFAPAVLGDVGLDRLPDLAWSDELAGYVTAEAAAQTGLREDTPV
AVGTVDALSEAVSVGAVHPGDLMVMYGSTTFFILVQDTPTPDPRVWTVGGAFAGQVNLAAGMSTTGSLTRWFVDELAREY
STEQAYDRLFAEAAHLAPGAEGLLLLPYFSGERTPINDPQARGVIAGLTLAHTRAHLFRAALEGVGYGIRQNIEAFRELG
AQVRRLVAVGGGAKGRTWLQIVSDISGEVQELPEVTVGASYGDAFLAGLAAGVLRRDDLNRWVRIADRVDPNPALKADYD
RLYGLYRDLYAQTRGTVHALSRPSA

Sequences:

>Translated_505_residues
MSAELLIGIDVGTYSSKGVLVTLDGQILRQHVIPHGINLPAPGHVEQDAEEVWWGDTLALLRELLKDPYSGADVAGIALS
AIGPTLLPLDGAGRPLRPGILYGVDTRAGAQIDALNREIGEAAILAHSGMSLTSQAIGPKIRWLREREPEVWAQTRTLTT
ASSYLTYRLTGRHVLDHHTAAHSMPLYDPRTRAWTAQFAPAVLGDVGLDRLPDLAWSDELAGYVTAEAAAQTGLREDTPV
AVGTVDALSEAVSVGAVHPGDLMVMYGSTTFFILVQDTPTPDPRVWTVGGAFAGQVNLAAGMSTTGSLTRWFVDELAREY
STEQAYDRLFAEAAHLAPGAEGLLLLPYFSGERTPINDPQARGVIAGLTLAHTRAHLFRAALEGVGYGIRQNIEAFRELG
AQVRRLVAVGGGAKGRTWLQIVSDISGEVQELPEVTVGASYGDAFLAGLAAGVLRRDDLNRWVRIADRVDPNPALKADYD
RLYGLYRDLYAQTRGTVHALSRPSA
>Mature_504_residues
SAELLIGIDVGTYSSKGVLVTLDGQILRQHVIPHGINLPAPGHVEQDAEEVWWGDTLALLRELLKDPYSGADVAGIALSA
IGPTLLPLDGAGRPLRPGILYGVDTRAGAQIDALNREIGEAAILAHSGMSLTSQAIGPKIRWLREREPEVWAQTRTLTTA
SSYLTYRLTGRHVLDHHTAAHSMPLYDPRTRAWTAQFAPAVLGDVGLDRLPDLAWSDELAGYVTAEAAAQTGLREDTPVA
VGTVDALSEAVSVGAVHPGDLMVMYGSTTFFILVQDTPTPDPRVWTVGGAFAGQVNLAAGMSTTGSLTRWFVDELAREYS
TEQAYDRLFAEAAHLAPGAEGLLLLPYFSGERTPINDPQARGVIAGLTLAHTRAHLFRAALEGVGYGIRQNIEAFRELGA
QVRRLVAVGGGAKGRTWLQIVSDISGEVQELPEVTVGASYGDAFLAGLAAGVLRRDDLNRWVRIADRVDPNPALKADYDR
LYGLYRDLYAQTRGTVHALSRPSA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=447, Percent_Identity=23.7136465324385, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI41393575, Length=438, Percent_Identity=23.2876712328767, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI189409120, Length=447, Percent_Identity=23.9373601789709, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4504007, Length=447, Percent_Identity=23.9373601789709, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI88196792, Length=486, Percent_Identity=23.2510288065844, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789987, Length=455, Percent_Identity=32.0879120879121, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790005, Length=507, Percent_Identity=27.2189349112426, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790361, Length=476, Percent_Identity=26.4705882352941, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787789, Length=515, Percent_Identity=26.4077669902913, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789168, Length=455, Percent_Identity=25.4945054945055, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789138, Length=518, Percent_Identity=22.3938223938224, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786249, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=458, Percent_Identity=25.1091703056769, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24657106, Length=480, Percent_Identity=23.5416666666667, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24657102, Length=480, Percent_Identity=23.5416666666667, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24655555, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24655560, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24655570, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24655574, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24655565, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656367, Length=500, Percent_Identity=21.6, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357867, Length=516, Percent_Identity=20.9302325581395, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656372, Length=145, Percent_Identity=29.6551724137931, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54244; Mature: 54113

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELLIGIDVGTYSSKGVLVTLDGQILRQHVIPHGINLPAPGHVEQDAEEVWWGDTLAL
CCCCEEEEEEECCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHH
LRELLKDPYSGADVAGIALSAIGPTLLPLDGAGRPLRPGILYGVDTRAGAQIDALNREIG
HHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHC
EAAILAHSGMSLTSQAIGPKIRWLREREPEVWAQTRTLTTASSYLTYRLTGRHVLDHHTA
CCCEEEECCCCHHHHHCCCHHHHHHCCCCHHHHHHHEEEECCCEEEEEECCCHHHHHHHH
AHSMPLYDPRTRAWTAQFAPAVLGDVGLDRLPDLAWSDELAGYVTAEAAAQTGLREDTPV
HCCCCCCCCCCCEEEHHHHHHHHHHCCHHHCCCCCCCHHHCHHEEHHHHHHCCCCCCCCE
AVGTVDALSEAVSVGAVHPGDLMVMYGSTTFFILVQDTPTPDPRVWTVGGAFAGQVNLAA
EEECHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCEEEEC
GMSTTGSLTRWFVDELAREYSTEQAYDRLFAEAAHLAPGAEGLLLLPYFSGERTPINDPQ
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCH
ARGVIAGLTLAHTRAHLFRAALEGVGYGIRQNIEAFRELGAQVRRLVAVGGGAKGRTWLQ
HCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IVSDISGEVQELPEVTVGASYGDAFLAGLAAGVLRRDDLNRWVRIADRVDPNPALKADYD
HHHHHCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RLYGLYRDLYAQTRGTVHALSRPSA
HHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
SAELLIGIDVGTYSSKGVLVTLDGQILRQHVIPHGINLPAPGHVEQDAEEVWWGDTLAL
CCCEEEEEEECCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHH
LRELLKDPYSGADVAGIALSAIGPTLLPLDGAGRPLRPGILYGVDTRAGAQIDALNREIG
HHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHC
EAAILAHSGMSLTSQAIGPKIRWLREREPEVWAQTRTLTTASSYLTYRLTGRHVLDHHTA
CCCEEEECCCCHHHHHCCCHHHHHHCCCCHHHHHHHEEEECCCEEEEEECCCHHHHHHHH
AHSMPLYDPRTRAWTAQFAPAVLGDVGLDRLPDLAWSDELAGYVTAEAAAQTGLREDTPV
HCCCCCCCCCCCEEEHHHHHHHHHHCCHHHCCCCCCCHHHCHHEEHHHHHHCCCCCCCCE
AVGTVDALSEAVSVGAVHPGDLMVMYGSTTFFILVQDTPTPDPRVWTVGGAFAGQVNLAA
EEECHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCEEEEC
GMSTTGSLTRWFVDELAREYSTEQAYDRLFAEAAHLAPGAEGLLLLPYFSGERTPINDPQ
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCH
ARGVIAGLTLAHTRAHLFRAALEGVGYGIRQNIEAFRELGAQVRRLVAVGGGAKGRTWLQ
HCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IVSDISGEVQELPEVTVGASYGDAFLAGLAAGVLRRDDLNRWVRIADRVDPNPALKADYD
HHHHHCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RLYGLYRDLYAQTRGTVHALSRPSA
HHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]