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The map label for this gene is degU [H]

Identifier: 94972309

GI number: 94972309

Start: 178499

End: 179128

Strand: Direct

Name: degU [H]

Synonym: Dgeo_2846

Alternate gene names: 94972309

Gene position: 178499-179128 (Clockwise)

Preceding gene: 94972310

Following gene: 94972304

Centisome position: 31.09

GC content: 66.98

Gene sequence:

>630_bases
ATGCCTGAACCTATCCGCATCCTGATCGTCGAGGACCATGCCTTTACCCGCGATGGCCTGCGTGCGAGCCTCAATCTCGA
AGCGGATCTGCGCGTCGTAGCAGAGGCCCGCAGCGGGGAGGAGGCCCTGGAGGTGCTGCGGGGGCAGGCGGCGGACGTGG
CCATTGTGGATATCGGCCTACCCGGCATGGACGGCATCCAGGCCGCCCGTGAACTCAAGCGGCGCTGGCCGGAGCTGCGG
ATTGTGATGCTCACCGCCCACGACCTGCGGGAGGAAGTCTTTGCGTCTCTGGCTTCGGGCGCTGATGCCTACTGCCTGAA
AAGCGCTCGCCCGGACCTGCTGCTGCTGGCGGTACGGGCTGCGGCTGCGGGCAGCGCCTACCTCGATCCCCAGGTGGCCC
ACCACGTGCTGGGGGGGGTGCGTGCTCCCGACGCCGGAGCACCCCTCACGCCGCGAGAACTTGACGTCCTGCGCTTGATC
GCAGACGGTCTCGCCAACAAGGAAATCGCCGCGGCCCTGGAGATCAGTGTGAGTACCGTCAAGCTGCACGTGCAAGAAAT
CCTGGTCAAGTTGCAGGCGGCAGACCGCACGCAGGCCGCTGTCAAGGCCCTGCGCGCCGGTCTCCTCTGA

Upstream 100 bases:

>100_bases
ACCCGCCGAATTGCCGAGGCGCACGGAGGCAGTGTTCGGTATCACCGCACGGCGCAGGCCAGAAGCCTCTTTGTCCTGAC
CCTTCCCCTGGAGACCCGAC

Downstream 100 bases:

>100_bases
GGTGGCCAGAACACGGGGTCGGTTGGTGGATGTTTGATCGGCCCTGCGGATGCCGGGCAAACGCGTGCGGGACCCTGTTA
GGTCGTGGGCAGCGCGAAGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MPEPIRILIVEDHAFTRDGLRASLNLEADLRVVAEARSGEEALEVLRGQAADVAIVDIGLPGMDGIQAARELKRRWPELR
IVMLTAHDLREEVFASLASGADAYCLKSARPDLLLLAVRAAAAGSAYLDPQVAHHVLGGVRAPDAGAPLTPRELDVLRLI
ADGLANKEIAAALEISVSTVKLHVQEILVKLQAADRTQAAVKALRAGLL

Sequences:

>Translated_209_residues
MPEPIRILIVEDHAFTRDGLRASLNLEADLRVVAEARSGEEALEVLRGQAADVAIVDIGLPGMDGIQAARELKRRWPELR
IVMLTAHDLREEVFASLASGADAYCLKSARPDLLLLAVRAAAAGSAYLDPQVAHHVLGGVRAPDAGAPLTPRELDVLRLI
ADGLANKEIAAALEISVSTVKLHVQEILVKLQAADRTQAAVKALRAGLL
>Mature_208_residues
PEPIRILIVEDHAFTRDGLRASLNLEADLRVVAEARSGEEALEVLRGQAADVAIVDIGLPGMDGIQAARELKRRWPELRI
VMLTAHDLREEVFASLASGADAYCLKSARPDLLLLAVRAAAAGSAYLDPQVAHHVLGGVRAPDAGAPLTPRELDVLRLIA
DGLANKEIAAALEISVSTVKLHVQEILVKLQAADRTQAAVKALRAGLL

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=38.2075471698113, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787473, Length=204, Percent_Identity=37.7450980392157, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=36.2244897959184, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=30.2884615384615, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786747, Length=194, Percent_Identity=24.7422680412371, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788712, Length=187, Percent_Identity=25.668449197861, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788546, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1789402, Length=211, Percent_Identity=30.3317535545024, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22302; Mature: 22171

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPIRILIVEDHAFTRDGLRASLNLEADLRVVAEARSGEEALEVLRGQAADVAIVDIGL
CCCCEEEEEEECCCCCCCCCEEEECCCCHHEEEEECCCCHHHHHHHCCCCCCEEEEEECC
PGMDGIQAARELKRRWPELRIVMLTAHDLREEVFASLASGADAYCLKSARPDLLLLAVRA
CCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEHH
AAAGSAYLDPQVAHHVLGGVRAPDAGAPLTPRELDVLRLIADGLANKEIAAALEISVSTV
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLHVQEILVKLQAADRTQAAVKALRAGLL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEPIRILIVEDHAFTRDGLRASLNLEADLRVVAEARSGEEALEVLRGQAADVAIVDIGL
CCCEEEEEEECCCCCCCCCEEEECCCCHHEEEEECCCCHHHHHHHCCCCCCEEEEEECC
PGMDGIQAARELKRRWPELRIVMLTAHDLREEVFASLASGADAYCLKSARPDLLLLAVRA
CCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEHH
AAAGSAYLDPQVAHHVLGGVRAPDAGAPLTPRELDVLRLIADGLANKEIAAALEISVSTV
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLHVQEILVKLQAADRTQAAVKALRAGLL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]