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The map label for this gene is sasA [H]

Identifier: 94972310

GI number: 94972310

Start: 176965

End: 178506

Strand: Direct

Name: sasA [H]

Synonym: Dgeo_2847

Alternate gene names: 94972310

Gene position: 176965-178506 (Clockwise)

Preceding gene: 94972319

Following gene: 94972309

Centisome position: 30.82

GC content: 67.38

Gene sequence:

>1542_bases
ATGCCTGCCCTGATCCCCCGCGACGTGGTGCGCGTCCGCTTTCCCTCACCCCGGCTGCCTCTGAGCGAGGGGACCGTGTG
GGGCGTGGCGTTGACCCTGATGGCCGCCGTGTTGCTGGCCGACATCCTGACTCCCGCCTCACTTGCTGTGGGTACGGTTC
TCAGCGCTTCGGTGGCCTTTGCGGCGCTGGGTGCCTCGCGGCGCACCGCCTGGCGCCTAACCGGTCTGGCCGTGCTGGCG
AATCTGGCTGCGGGTCTTTGGAACGGTGTGCGCGACGGCGTGCATCCCACAGATCTGGCCAACCGAGCGGTGAGCATCCT
GGCCGTTTTGTTGGTCGGTTACCTGACCATCCGCGCGCGGGAAGCCTCCGAGCGGGCCGCCGCCCTGCAGGAGGAGGAGC
GGCAACTTCGGCGGGAACGGGCTTTGCGCAGCTTGGCGGAGGATATGGGCGGTCCCTTGGGGCAGGCAGAGTTTGTGGAG
CGGGCCGCCGCGGCGCTGGTACGGCTGACTGGCGCCAGGACTGTTGAGATCGGTGCGGTGGACCGAGCGACCCTCCGCGC
GCCGCATGCTCTGGCCTGCGCGCCAGGTGCCTTTCCAGCCCCAAGTCGCCTCAATACCCGGATTCCGCTCGAATTCCTGG
CGCATCCGGTCGGGTCTGGAGATGTGTGGGCGGTGGACGGTGGCCGCGTCTTCCTGGCCCGGTTGCGCCGCCCCGCTGCC
GGCGACCTGTTGGTGATCCTGACCGCCCCCACCACACCGCCTAACCTGACGAGCGAGGCCATCCGGGCGTTGCAACCCCT
GCTGGAACGCACCGCTTTGCTCGACGATCTGCGCGCAAACCGGGAGCAATTGGCCGAGCAGAGCGAATTGCTGCGTGACC
TGATCTACGCTTTTTCCCATGACCTGCGCACGCCCCTCCTCGCCAACGCCATGAACATGCAGGCGGCCCTGAAGGGCGCT
TATGGTCCCCTCCCAGAGGCATACCGCGCCACGCTGGTCAACGGGCTTAGCGCCAATGAGACCCTCCTCAACCTGGCCGA
CCAACTGCTGCTGGTCGCCCGGTACGAGAGCGGCGTAGAGGCGGGGGAAGACCACCTGAGCGTGAACCTGCGTGACCTCG
TTCTCCATGTGGTGAATGATCTGCGCCCCCACGCCCAGGCGCGGCGAGTTACCTTTGAGCTCCACCTGGACGGCGTGCGG
GTCTGCGGCAATCCCCATGACCTGCGGCGAGCCGTCCAGAATCTGCTGGACAATGCGATCAAATTCAGTCCACCCGGCGG
AACGGTGAGCCTTGGCCTCTTGGCAGATGGCGACGAGGCTGTGTTCAGCGTGCAGGATGAGGGTCCCGGTGTTCCGCCTG
GCCGGGAGGGGCGGCTGTTCCAGCGCTTCCGCAGTGGCGGAGCCGGGGGCGGTACCGGCCTGGGCCTCTACCTGACCCGC
CGAATTGCCGAGGCGCACGGAGGCAGTGTTCGGTATCACCGCACGGCGCAGGCCAGAAGCCTCTTTGTCCTGACCCTTCC
CCTGGAGACCCGACATGCCTGA

Upstream 100 bases:

>100_bases
GCTGATTCTGCTGATTCTGGCTCTCCAAGACACGTGAGAGCCGCGCCCCCTGCTCTCTTCCCCAAGCCTCCGTCATGTGC
CGCTGTCCTACCCTGACCCC

Downstream 100 bases:

>100_bases
ACCTATCCGCATCCTGATCGTCGAGGACCATGCCTTTACCCGCGATGGCCTGCGTGCGAGCCTCAATCTCGAAGCGGATC
TGCGCGTCGTAGCAGAGGCC

Product: histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MPALIPRDVVRVRFPSPRLPLSEGTVWGVALTLMAAVLLADILTPASLAVGTVLSASVAFAALGASRRTAWRLTGLAVLA
NLAAGLWNGVRDGVHPTDLANRAVSILAVLLVGYLTIRAREASERAAALQEEERQLRRERALRSLAEDMGGPLGQAEFVE
RAAAALVRLTGARTVEIGAVDRATLRAPHALACAPGAFPAPSRLNTRIPLEFLAHPVGSGDVWAVDGGRVFLARLRRPAA
GDLLVILTAPTTPPNLTSEAIRALQPLLERTALLDDLRANREQLAEQSELLRDLIYAFSHDLRTPLLANAMNMQAALKGA
YGPLPEAYRATLVNGLSANETLLNLADQLLLVARYESGVEAGEDHLSVNLRDLVLHVVNDLRPHAQARRVTFELHLDGVR
VCGNPHDLRRAVQNLLDNAIKFSPPGGTVSLGLLADGDEAVFSVQDEGPGVPPGREGRLFQRFRSGGAGGGTGLGLYLTR
RIAEAHGGSVRYHRTAQARSLFVLTLPLETRHA

Sequences:

>Translated_513_residues
MPALIPRDVVRVRFPSPRLPLSEGTVWGVALTLMAAVLLADILTPASLAVGTVLSASVAFAALGASRRTAWRLTGLAVLA
NLAAGLWNGVRDGVHPTDLANRAVSILAVLLVGYLTIRAREASERAAALQEEERQLRRERALRSLAEDMGGPLGQAEFVE
RAAAALVRLTGARTVEIGAVDRATLRAPHALACAPGAFPAPSRLNTRIPLEFLAHPVGSGDVWAVDGGRVFLARLRRPAA
GDLLVILTAPTTPPNLTSEAIRALQPLLERTALLDDLRANREQLAEQSELLRDLIYAFSHDLRTPLLANAMNMQAALKGA
YGPLPEAYRATLVNGLSANETLLNLADQLLLVARYESGVEAGEDHLSVNLRDLVLHVVNDLRPHAQARRVTFELHLDGVR
VCGNPHDLRRAVQNLLDNAIKFSPPGGTVSLGLLADGDEAVFSVQDEGPGVPPGREGRLFQRFRSGGAGGGTGLGLYLTR
RIAEAHGGSVRYHRTAQARSLFVLTLPLETRHA
>Mature_512_residues
PALIPRDVVRVRFPSPRLPLSEGTVWGVALTLMAAVLLADILTPASLAVGTVLSASVAFAALGASRRTAWRLTGLAVLAN
LAAGLWNGVRDGVHPTDLANRAVSILAVLLVGYLTIRAREASERAAALQEEERQLRRERALRSLAEDMGGPLGQAEFVER
AAAALVRLTGARTVEIGAVDRATLRAPHALACAPGAFPAPSRLNTRIPLEFLAHPVGSGDVWAVDGGRVFLARLRRPAAG
DLLVILTAPTTPPNLTSEAIRALQPLLERTALLDDLRANREQLAEQSELLRDLIYAFSHDLRTPLLANAMNMQAALKGAY
GPLPEAYRATLVNGLSANETLLNLADQLLLVARYESGVEAGEDHLSVNLRDLVLHVVNDLRPHAQARRVTFELHLDGVRV
CGNPHDLRRAVQNLLDNAIKFSPPGGTVSLGLLADGDEAVFSVQDEGPGVPPGREGRLFQRFRSGGAGGGTGLGLYLTRR
IAEAHGGSVRYHRTAQARSLFVLTLPLETRHA

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790861, Length=286, Percent_Identity=29.3706293706294, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=33.9901477832512, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786912, Length=284, Percent_Identity=30.6338028169014, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=30.5555555555556, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786600, Length=303, Percent_Identity=27.0627062706271, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=27.1929824561404, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=282, Percent_Identity=27.3049645390071, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=194, Percent_Identity=30.9278350515464, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=24.0458015267176, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 54875; Mature: 54744

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALIPRDVVRVRFPSPRLPLSEGTVWGVALTLMAAVLLADILTPASLAVGTVLSASVAF
CCCCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AALGASRRTAWRLTGLAVLANLAAGLWNGVRDGVHPTDLANRAVSILAVLLVGYLTIRAR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EASERAAALQEEERQLRRERALRSLAEDMGGPLGQAEFVERAAAALVRLTGARTVEIGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCC
DRATLRAPHALACAPGAFPAPSRLNTRIPLEFLAHPVGSGDVWAVDGGRVFLARLRRPAA
CHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHCCCCC
GDLLVILTAPTTPPNLTSEAIRALQPLLERTALLDDLRANREQLAEQSELLRDLIYAFSH
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRTPLLANAMNMQAALKGAYGPLPEAYRATLVNGLSANETLLNLADQLLLVARYESGVE
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
AGEDHLSVNLRDLVLHVVNDLRPHAQARRVTFELHLDGVRVCGNPHDLRRAVQNLLDNAI
CCCHHHCCHHHHHHHHHHHHHCCCHHHHEEEEEEEECCEEECCCHHHHHHHHHHHHHHHE
KFSPPGGTVSLGLLADGDEAVFSVQDEGPGVPPGREGRLFQRFRSGGAGGGTGLGLYLTR
EECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHH
RIAEAHGGSVRYHRTAQARSLFVLTLPLETRHA
HHHHHCCCCEEEEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
PALIPRDVVRVRFPSPRLPLSEGTVWGVALTLMAAVLLADILTPASLAVGTVLSASVAF
CCCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AALGASRRTAWRLTGLAVLANLAAGLWNGVRDGVHPTDLANRAVSILAVLLVGYLTIRAR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EASERAAALQEEERQLRRERALRSLAEDMGGPLGQAEFVERAAAALVRLTGARTVEIGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCC
DRATLRAPHALACAPGAFPAPSRLNTRIPLEFLAHPVGSGDVWAVDGGRVFLARLRRPAA
CHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHCCCCC
GDLLVILTAPTTPPNLTSEAIRALQPLLERTALLDDLRANREQLAEQSELLRDLIYAFSH
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRTPLLANAMNMQAALKGAYGPLPEAYRATLVNGLSANETLLNLADQLLLVARYESGVE
HCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
AGEDHLSVNLRDLVLHVVNDLRPHAQARRVTFELHLDGVRVCGNPHDLRRAVQNLLDNAI
CCCHHHCCHHHHHHHHHHHHHCCCHHHHEEEEEEEECCEEECCCHHHHHHHHHHHHHHHE
KFSPPGGTVSLGLLADGDEAVFSVQDEGPGVPPGREGRLFQRFRSGGAGGGTGLGLYLTR
EECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHH
RIAEAHGGSVRYHRTAQARSLFVLTLPLETRHA
HHHHHCCCCEEEEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA