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The map label for this gene is hexR [C]

Identifier: 94972285

GI number: 94972285

Start: 205845

End: 206717

Strand: Direct

Name: hexR [C]

Synonym: Dgeo_2822

Alternate gene names: 94972285

Gene position: 205845-206717 (Clockwise)

Preceding gene: 94972291

Following gene: 94972284

Centisome position: 35.85

GC content: 64.26

Gene sequence:

>873_bases
ATGGCGACTCCACCTGCCCATCTTCCTCCAGTCCTGCGCCGCCTCCACCTCCTGCGTGAGGAACAGGGTGCTGCTACCGT
GCGCGTCATCGATCAGATCCTGATGGATCCAGAGCGGTTTCTGTCGCTGACCATCGCGGAACTCAGCGAGGCAGCCGGCA
CCAGTGACGCCACGGTCGTGCGGCTGGTGCAGCATCTGGGGTTCGGTGGGTATCAGGAGTTCAAGCTGCAGCTCTCGCGG
GCACTGGCGGTCAGCCGAAAAGCCGACCTGACCGTGGAGCCCCAGGACGCCTCAGTCACCATCTTGCGCAAGATCTTCGA
CTCGTCCAATACAGCATTGGATGACACGCTAGAACACCTGAACCTGGAGGCCTTTAGCGCTGCCGTGCAGGCCATGACGC
TCGCGCGGCATATCGAACTGATCGGGATGGGGGCCAGCGGTGTGGTGGCTTTGAGCGGTCAGTACCGGGGCCTGCGGCTG
GGCTTATCCTGCCGGGCAAGCACCGATCCTGGCACTTTCCTCTCCACCTGCTCGCTGCTTGAACCAACCGACGTGCTGAT
CGCGGTGTCCTTTAGTGGCACGCGGCCACAGGTGGTTCAGGCAGCACGACTGGCACGGCAGGCCGGCGCCATCGTCGTGG
CTCTGACGGGATTGGGACGCACGCCGCTCAGCAAGGTCGTGCATCACACGCTGACCGTTTCAGCACCCGGAGACCGCTAT
CGCCCTGAAGGCCTGGCGACGCAGATCCCTCAGGTGGCGATCCTAGACGCCCTGTTTACCAGCCTGCACGTCGCGCAGGA
TCCCTATCTCTCTGAGCGGCTCTCGCGCGCAGCCGCAGCCCGGCGCGCCCTCAACGCTGAGCCTTCCCCCTAA

Upstream 100 bases:

>100_bases
CTGCTGATCTTCCAATCCATGAAAGAGGAGCGTACAGTTCGGTTGGTCTTCACAGTTCAGGTTGTTCTCTGCGCAGCTCG
TCCACCTTGGTGTCTTTGCT

Downstream 100 bases:

>100_bases
CCCCCGCCTCTCACCCCCTAAGGAGATCCTGTATGCGTCGCCTGACTCTGCTGTTTGCCCTGCCCGGTCTACTGGTCGCT
GTGCCTGCCCATGCCCAGAG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MATPPAHLPPVLRRLHLLREEQGAATVRVIDQILMDPERFLSLTIAELSEAAGTSDATVVRLVQHLGFGGYQEFKLQLSR
ALAVSRKADLTVEPQDASVTILRKIFDSSNTALDDTLEHLNLEAFSAAVQAMTLARHIELIGMGASGVVALSGQYRGLRL
GLSCRASTDPGTFLSTCSLLEPTDVLIAVSFSGTRPQVVQAARLARQAGAIVVALTGLGRTPLSKVVHHTLTVSAPGDRY
RPEGLATQIPQVAILDALFTSLHVAQDPYLSERLSRAAAARRALNAEPSP

Sequences:

>Translated_290_residues
MATPPAHLPPVLRRLHLLREEQGAATVRVIDQILMDPERFLSLTIAELSEAAGTSDATVVRLVQHLGFGGYQEFKLQLSR
ALAVSRKADLTVEPQDASVTILRKIFDSSNTALDDTLEHLNLEAFSAAVQAMTLARHIELIGMGASGVVALSGQYRGLRL
GLSCRASTDPGTFLSTCSLLEPTDVLIAVSFSGTRPQVVQAARLARQAGAIVVALTGLGRTPLSKVVHHTLTVSAPGDRY
RPEGLATQIPQVAILDALFTSLHVAQDPYLSERLSRAAAARRALNAEPSP
>Mature_289_residues
ATPPAHLPPVLRRLHLLREEQGAATVRVIDQILMDPERFLSLTIAELSEAAGTSDATVVRLVQHLGFGGYQEFKLQLSRA
LAVSRKADLTVEPQDASVTILRKIFDSSNTALDDTLEHLNLEAFSAAVQAMTLARHIELIGMGASGVVALSGQYRGLRLG
LSCRASTDPGTFLSTCSLLEPTDVLIAVSFSGTRPQVVQAARLARQAGAIVVALTGLGRTPLSKVVHHTLTVSAPGDRYR
PEGLATQIPQVAILDALFTSLHVAQDPYLSERLSRAAAARRALNAEPSP

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=272, Percent_Identity=28.6764705882353, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788767, Length=245, Percent_Identity=26.1224489795918, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082369, Length=260, Percent_Identity=25.3846153846154, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082130, Length=271, Percent_Identity=29.1512915129151, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30978; Mature: 30847

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPPAHLPPVLRRLHLLREEQGAATVRVIDQILMDPERFLSLTIAELSEAAGTSDATVV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHH
RLVQHLGFGGYQEFKLQLSRALAVSRKADLTVEPQDASVTILRKIFDSSNTALDDTLEHL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHH
NLEAFSAAVQAMTLARHIELIGMGASGVVALSGQYRGLRLGLSCRASTDPGTFLSTCSLL
CHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHCCC
EPTDVLIAVSFSGTRPQVVQAARLARQAGAIVVALTGLGRTPLSKVVHHTLTVSAPGDRY
CCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHEEEECCCCCC
RPEGLATQIPQVAILDALFTSLHVAQDPYLSERLSRAAAARRALNAEPSP
CCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATPPAHLPPVLRRLHLLREEQGAATVRVIDQILMDPERFLSLTIAELSEAAGTSDATVV
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHH
RLVQHLGFGGYQEFKLQLSRALAVSRKADLTVEPQDASVTILRKIFDSSNTALDDTLEHL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHH
NLEAFSAAVQAMTLARHIELIGMGASGVVALSGQYRGLRLGLSCRASTDPGTFLSTCSLL
CHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEEEEEEECCCCCCHHHHHHCCC
EPTDVLIAVSFSGTRPQVVQAARLARQAGAIVVALTGLGRTPLSKVVHHTLTVSAPGDRY
CCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHEEEECCCCCC
RPEGLATQIPQVAILDALFTSLHVAQDPYLSERLSRAAAARRALNAEPSP
CCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]