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The map label for this gene is dgoD1 [H]

Identifier: 94972276

GI number: 94972276

Start: 215879

End: 217027

Strand: Direct

Name: dgoD1 [H]

Synonym: Dgeo_2811

Alternate gene names: 94972276

Gene position: 215879-217027 (Clockwise)

Preceding gene: 94972277

Following gene: 94972271

Centisome position: 37.6

GC content: 62.32

Gene sequence:

>1149_bases
ATGAAGATCACCAATATCGAAACCTTTCTGGTGCCGCCACGCTGGTGCTTTTTGAAACTTGAAACGGACGAGGGCATCGT
GGGGTGGGGTGAACCGGTGGTAGAAGGCCGGGCGCACACGGTGCAGGCCGCTGTGCATGAACTGGCCGACTACCTGCTAG
GGCAAGATCCCCAGCGGATTGAGGACCTGTGGCAGGTGATGTATCGGGGCGGGTTCTACCGGGGTGGGGCTGTCTTTATG
AGTGCCCTTGCCGGCATCGATCAGGCGCTGTGGGACATCAAGGGCCAGGCGCTGGGGACGCCAGTCTACAATCTACTGGG
GGGAGCCTGTCGGGACCGTATCCGGGTGTATTCCTGGATCGGCGGCGACCGGCCCGCTGAGGTGGGGGAGGCGGCTCGCC
GAGCGCACAGGGCGGGCTTTACCGCCATCAAGATGAACGCCACCGAGGAACTCCAGTATGTGGATTCGTACGCCAAGGTG
GACGCCGTGCTTGCCCGCGTGCAGGCGGTGCGCGAAGCAACCACACCGGATTTTGGCATTGCGGTGGATTTTCATGGCCG
GGTGCACCGCCCGATGGCCCAGGTGCTGGTTCGCGAACTCGAGCCTTATCGGCTGATGTTCATTGAGGAACCCGTTCTGT
CGGAGCATCTCGAGGCACTGCGCGACGTCAAACGGGCGACCACAACACCGCTCGCCCTGGGAGAGCGACTCTACTCACGC
TGGGATTTCAAACAGGTCCTGCAAGAAGGTCTGGCTGACATCCTGCAACCGGACCTATCCCATGCTGGTGGGATTAGTGA
GTGTCGTAAGATTGCTGCGATGGCTGAAGCCTACGACGTGGCGCTCGCTCCGCACTGCCCGTTGGGGCCCATCGCTTTGG
CCGCCTGCCTCCAGATCGACGCCGTATCGCACAATGCCATCATTCAGGAGCAGAGTCTGGGCATCCATTACAACGCTGGA
AGTGACCTGCTCGACTACCTGACCGACGCCGCCGTCTTCGAATATGCCGACGGTTTTGTGCAGCTCCCTGCGGGGCCAGG
GCTCGGGCTGCAGCTCAACGAAGAACTGGTGCGTGAGCAGGCCCGCCTAGGCCACCGCTGGCGCAATCCGGTCTGGCGTC
ATGCGGACGGCAGCGTGGCCGAGTGGTGA

Upstream 100 bases:

>100_bases
TGGAGCAACCCCAACTGGGCCGAGCTCCAGCAGGTCGCTGAGGAAATGATGCAGTGCGCAACCAATCCATGATCCTTTTG
TCAAGCTCCGGAGTTACAGA

Downstream 100 bases:

>100_bases
GCTGCGGTCGTGAGGGAGCAGCGGCGGGACGCTACACCTCCTGGTGGTAGGGACAATCGGGTTGAACGGGTCGTCCCCAG
CTTCTCGGCTTTTGGCGCCA

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKITNIETFLVPPRWCFLKLETDEGIVGWGEPVVEGRAHTVQAAVHELADYLLGQDPQRIEDLWQVMYRGGFYRGGAVFM
SALAGIDQALWDIKGQALGTPVYNLLGGACRDRIRVYSWIGGDRPAEVGEAARRAHRAGFTAIKMNATEELQYVDSYAKV
DAVLARVQAVREATTPDFGIAVDFHGRVHRPMAQVLVRELEPYRLMFIEEPVLSEHLEALRDVKRATTTPLALGERLYSR
WDFKQVLQEGLADILQPDLSHAGGISECRKIAAMAEAYDVALAPHCPLGPIALAACLQIDAVSHNAIIQEQSLGIHYNAG
SDLLDYLTDAAVFEYADGFVQLPAGPGLGLQLNEELVREQARLGHRWRNPVWRHADGSVAEW

Sequences:

>Translated_382_residues
MKITNIETFLVPPRWCFLKLETDEGIVGWGEPVVEGRAHTVQAAVHELADYLLGQDPQRIEDLWQVMYRGGFYRGGAVFM
SALAGIDQALWDIKGQALGTPVYNLLGGACRDRIRVYSWIGGDRPAEVGEAARRAHRAGFTAIKMNATEELQYVDSYAKV
DAVLARVQAVREATTPDFGIAVDFHGRVHRPMAQVLVRELEPYRLMFIEEPVLSEHLEALRDVKRATTTPLALGERLYSR
WDFKQVLQEGLADILQPDLSHAGGISECRKIAAMAEAYDVALAPHCPLGPIALAACLQIDAVSHNAIIQEQSLGIHYNAG
SDLLDYLTDAAVFEYADGFVQLPAGPGLGLQLNEELVREQARLGHRWRNPVWRHADGSVAEW
>Mature_382_residues
MKITNIETFLVPPRWCFLKLETDEGIVGWGEPVVEGRAHTVQAAVHELADYLLGQDPQRIEDLWQVMYRGGFYRGGAVFM
SALAGIDQALWDIKGQALGTPVYNLLGGACRDRIRVYSWIGGDRPAEVGEAARRAHRAGFTAIKMNATEELQYVDSYAKV
DAVLARVQAVREATTPDFGIAVDFHGRVHRPMAQVLVRELEPYRLMFIEEPVLSEHLEALRDVKRATTTPLALGERLYSR
WDFKQVLQEGLADILQPDLSHAGGISECRKIAAMAEAYDVALAPHCPLGPIALAACLQIDAVSHNAIIQEQSLGIHYNAG
SDLLDYLTDAAVFEYADGFVQLPAGPGLGLQLNEELVREQARLGHRWRNPVWRHADGSVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=60.7329842931937, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1787864, Length=419, Percent_Identity=32.4582338902148, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI226510960, Length=217, Percent_Identity=32.258064516129, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42359; Mature: 42359

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITNIETFLVPPRWCFLKLETDEGIVGWGEPVVEGRAHTVQAAVHELADYLLGQDPQRI
CCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
EDLWQVMYRGGFYRGGAVFMSALAGIDQALWDIKGQALGTPVYNLLGGACRDRIRVYSWI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GGDRPAEVGEAARRAHRAGFTAIKMNATEELQYVDSYAKVDAVLARVQAVREATTPDFGI
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AVDFHGRVHRPMAQVLVRELEPYRLMFIEEPVLSEHLEALRDVKRATTTPLALGERLYSR
EEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WDFKQVLQEGLADILQPDLSHAGGISECRKIAAMAEAYDVALAPHCPLGPIALAACLQID
CCHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
AVSHNAIIQEQSLGIHYNAGSDLLDYLTDAAVFEYADGFVQLPAGPGLGLQLNEELVREQ
HCCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECHHHHHHH
ARLGHRWRNPVWRHADGSVAEW
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITNIETFLVPPRWCFLKLETDEGIVGWGEPVVEGRAHTVQAAVHELADYLLGQDPQRI
CCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
EDLWQVMYRGGFYRGGAVFMSALAGIDQALWDIKGQALGTPVYNLLGGACRDRIRVYSWI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GGDRPAEVGEAARRAHRAGFTAIKMNATEELQYVDSYAKVDAVLARVQAVREATTPDFGI
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
AVDFHGRVHRPMAQVLVRELEPYRLMFIEEPVLSEHLEALRDVKRATTTPLALGERLYSR
EEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
WDFKQVLQEGLADILQPDLSHAGGISECRKIAAMAEAYDVALAPHCPLGPIALAACLQID
CCHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
AVSHNAIIQEQSLGIHYNAGSDLLDYLTDAAVFEYADGFVQLPAGPGLGLQLNEELVREQ
HCCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCEECHHHHHHH
ARLGHRWRNPVWRHADGSVAEW
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA