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The map label for this gene is speB [H]

Identifier: 94972199

GI number: 94972199

Start: 294561

End: 295496

Strand: Direct

Name: speB [H]

Synonym: Dgeo_2732

Alternate gene names: 94972199

Gene position: 294561-295496 (Clockwise)

Preceding gene: 94972200

Following gene: 94972198

Centisome position: 51.31

GC content: 69.02

Gene sequence:

>936_bases
GTGGTCTCCATCAAGCAACCGAACTCCACCCCCCCCTCGCACCTTCCCTACGGCGGCATCGCCTCCTTCGCCCGCGCGCC
CACCTTTGAACCGGGCGGGAACTGGCAGGCCGACGTGGCCGTGTTGGGCATTCCGTATGACATCGCCCTCGGTTTTCGGC
CCGGGGCTCGCTACGCGCCGCGTGCGCTGCGGGAGGCCAGCTTGCGTTACGTGCCGCCCTTCACCGACCTGTCGGGGCGA
ACGCGGCTGGCGGACGTGACCTTCGCGGACGCCGGAGACGTGGTGCTGCCCAGCCTGGAACCCGAACTCGCCCGCGAACG
CATCACGCAGACGGCACGGCAGGTGAGGAAACGCGCCCGGCTTCCCGTCTTCCTGGGCGGCGACCACAGCGTGACCTATC
CGCTGCTGCGCGCCTTTGACGACCAGCCGGACCTACACGTCATCCAGCTCGACGCGCATCTCGACTTCACCGACGAACGG
AATGGCACGCGCTACAGCAATTCCAGTCCCTTTCGACGGGCGGCCGAAGACCTCTCCAATCTCGTTCACATCACGACGCT
GGGGCTGCGCGGCCTGAGACACGACCCCGAGGCTCTGGCGGCGGCGCGGACACGTGGGCACACCTTGGTGCCGATGGAGG
AGGTCGAAGCGCGGTTGGGCGAGGTGGTGACGGCCCTTCCCCCCGGCAGCCCGGTCTATCTCAGCGTGGATGCAGACGCC
TTCGATCCCGCCGTGTTGCCCGGCACCAGCAGCCCCGAGCCGGACGGCTTCAGCTACGCCCTTGCCCTGCGGGTGATCCG
CGAGGTGGTGCGGCGGCATCGCCTGGTCGGGATGGACCTCGTCGAACTCGCACCCAACCTCGACCCCAGCGGGCGCAGCG
CCCTGATCGGCGCGCGGCTGGTGATGGAGACGCTCTGCGAGGCCTTCGATGGCTGA

Upstream 100 bases:

>100_bases
TGCCCACCGCCTGACCCTCGCCACGCGCAACACGGCGGACTTTCTGGCCTTTCCCATTGCCGTCTTTAATCCCTGGTTAC
CCTAAACGGGGCGACCGGAG

Downstream 100 bases:

>100_bases
ACTGCTCTTGACTGGCATCACCCAGCTCGTGACGCCCCCGCCGGGACCGCAAAGGGGCGCGGCCATGCGGAAGCTGACGG
TGCTGCAGGACGCGGCGCTC

Product: arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MVSIKQPNSTPPSHLPYGGIASFARAPTFEPGGNWQADVAVLGIPYDIALGFRPGARYAPRALREASLRYVPPFTDLSGR
TRLADVTFADAGDVVLPSLEPELARERITQTARQVRKRARLPVFLGGDHSVTYPLLRAFDDQPDLHVIQLDAHLDFTDER
NGTRYSNSSPFRRAAEDLSNLVHITTLGLRGLRHDPEALAAARTRGHTLVPMEEVEARLGEVVTALPPGSPVYLSVDADA
FDPAVLPGTSSPEPDGFSYALALRVIREVVRRHRLVGMDLVELAPNLDPSGRSALIGARLVMETLCEAFDG

Sequences:

>Translated_311_residues
MVSIKQPNSTPPSHLPYGGIASFARAPTFEPGGNWQADVAVLGIPYDIALGFRPGARYAPRALREASLRYVPPFTDLSGR
TRLADVTFADAGDVVLPSLEPELARERITQTARQVRKRARLPVFLGGDHSVTYPLLRAFDDQPDLHVIQLDAHLDFTDER
NGTRYSNSSPFRRAAEDLSNLVHITTLGLRGLRHDPEALAAARTRGHTLVPMEEVEARLGEVVTALPPGSPVYLSVDADA
FDPAVLPGTSSPEPDGFSYALALRVIREVVRRHRLVGMDLVELAPNLDPSGRSALIGARLVMETLCEAFDG
>Mature_311_residues
MVSIKQPNSTPPSHLPYGGIASFARAPTFEPGGNWQADVAVLGIPYDIALGFRPGARYAPRALREASLRYVPPFTDLSGR
TRLADVTFADAGDVVLPSLEPELARERITQTARQVRKRARLPVFLGGDHSVTYPLLRAFDDQPDLHVIQLDAHLDFTDER
NGTRYSNSSPFRRAAEDLSNLVHITTLGLRGLRHDPEALAAARTRGHTLVPMEEVEARLGEVVTALPPGSPVYLSVDADA
FDPAVLPGTSSPEPDGFSYALALRVIREVVRRHRLVGMDLVELAPNLDPSGRSALIGARLVMETLCEAFDG

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=298, Percent_Identity=34.5637583892617, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI10947139, Length=279, Percent_Identity=26.1648745519713, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789306, Length=275, Percent_Identity=29.0909090909091, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33856; Mature: 33856

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIKQPNSTPPSHLPYGGIASFARAPTFEPGGNWQADVAVLGIPYDIALGFRPGARYAP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCHHH
RALREASLRYVPPFTDLSGRTRLADVTFADAGDVVLPSLEPELARERITQTARQVRKRAR
HHHHHCCCEECCCCCCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHCC
LPVFLGGDHSVTYPLLRAFDDQPDLHVIQLDAHLDFTDERNGTRYSNSSPFRRAAEDLSN
CCEEECCCCCHHHHHHHHCCCCCCEEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHHHH
LVHITTLGLRGLRHDPEALAAARTRGHTLVPMEEVEARLGEVVTALPPGSPVYLSVDADA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCEEEEECCCC
FDPAVLPGTSSPEPDGFSYALALRVIREVVRRHRLVGMDLVELAPNLDPSGRSALIGARL
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHH
VMETLCEAFDG
HHHHHHHHHCC
>Mature Secondary Structure
MVSIKQPNSTPPSHLPYGGIASFARAPTFEPGGNWQADVAVLGIPYDIALGFRPGARYAP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCHHH
RALREASLRYVPPFTDLSGRTRLADVTFADAGDVVLPSLEPELARERITQTARQVRKRAR
HHHHHCCCEECCCCCCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHCC
LPVFLGGDHSVTYPLLRAFDDQPDLHVIQLDAHLDFTDERNGTRYSNSSPFRRAAEDLSN
CCEEECCCCCHHHHHHHHCCCCCCEEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHHHH
LVHITTLGLRGLRHDPEALAAARTRGHTLVPMEEVEARLGEVVTALPPGSPVYLSVDADA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCCCEEEEECCCC
FDPAVLPGTSSPEPDGFSYALALRVIREVVRRHRLVGMDLVELAPNLDPSGRSALIGARL
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHH
VMETLCEAFDG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]