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The map label for this gene is hutI [H]

Identifier: 94972198

GI number: 94972198

Start: 295489

End: 296724

Strand: Direct

Name: hutI [H]

Synonym: Dgeo_2731

Alternate gene names: 94972198

Gene position: 295489-296724 (Clockwise)

Preceding gene: 94972199

Following gene: 94972197

Centisome position: 51.47

GC content: 71.36

Gene sequence:

>1236_bases
ATGGCTGAACTGCTCTTGACTGGCATCACCCAGCTCGTGACGCCCCCGCCGGGACCGCAAAGGGGCGCGGCCATGCGGAA
GCTGACGGTGCTGCAGGACGCGGCGCTCCTCATGCGTGACGGGATGATCGCGTGGGTGGGATCACGGCAGGAGGCGCCCG
CCGCCGCTCAGATCCGCGACTTGGGCGGCGTCGCCGTCGTTCCCGGCCTGGTCGACCCTCACACCCATGCGGTCTGGGCC
GGGGACCGCCTGGCCGATTTCGAGGCACGGGTGGAAGGCGTGCCCTACGAGGAGCTGCTGGCGCGGGGGGGCGGCATCCG
CTCCACCATGCAGGCGACGGCAACGGCAGGTGTGGAGGAACTTGCCCAGCTCGCCCACCCCCGCCTAGCGGCCCTGCTCC
ATTCCGGCGCGACCACCATCGAGGTCAAGAGCGGCTACGGGCTGGACTTTGGGGCCGAGTTGAGGATGCTGAAGGCGGTG
CGTGCGTTGCAGGAGAGCTTGCCGGCCACGCTCGTGCCCACGCTGCTGATTCACGTCCCGCCCACCGAAAGCCGCGCGGC
GTACGTCCGGGCGGTCTGTGAGGCCCTCATTCCCGAGGTGGCGCGCAAGCGCCTGGCTGCCGCTGTGGACGTGTTCTGCG
AGCGCGAAGCCTTCACGGTGGAGGAAACGCGTGCCCTCTTCGCGGCGGCCCGGTCGAATGGCCTGCAGGTCAAGCTGCAC
GCCGACCAGTTCCACGCCCTCGGCGGCACCGAACTTGCCTGCGCGGTGGAGGCGCTCAGCGTGGACCACCTGGAAGCCAG
CGGCGAGGCGCAGATCGAGGCGCTGGCCGCGTCGGAGACGGTGGCGACGGTCCTGCCCGGCGTCACGCTGCACCTGGGGC
TGAGGGCAGCCCCGGCCCGCCGCCTCGTGGACGCGGGCGCCTGCGTGGCGGTCGGTACGGACCTGAACCCCGGCAGCTCT
CCCCTCTTCAGCGCCCAGCTCGCGCTGGCCCTCGCGGTGCGGCTGAACGGCCTCACGCCCGCCGAGGCCCTCACCGCTTG
CACCGTGAACGCCGCCGCCGCACTGGGGCTGAGGGACCGGGGGGCACTGGTGGCTGGGCAGCGGGCCGACTTGCTCGCCC
TGCATGCCTCCGACTGGCGCGACCTGGCCTACACGCTGGGCGCAAACCCTGTCCGCGACGTGTTCGTGGGCGGGCAAAAC
ATCAAGGAGACTCTGAGCAAGGAGAAGGCCCTGTGA

Upstream 100 bases:

>100_bases
GGGATGGACCTCGTCGAACTCGCACCCAACCTCGACCCCAGCGGGCGCAGCGCCCTGATCGGCGCGCGGCTGGTGATGGA
GACGCTCTGCGAGGCCTTCG

Downstream 100 bases:

>100_bases
TCCTAGACCGGCAATTGACGCTTGACGACTTTATCCGCGTGGTGCGTGGCGGCGAGGAGGTGACCCTTGCTGATGCGGCG
CGGACACGGATGGGACGAGC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAELLLTGITQLVTPPPGPQRGAAMRKLTVLQDAALLMRDGMIAWVGSRQEAPAAAQIRDLGGVAVVPGLVDPHTHAVWA
GDRLADFEARVEGVPYEELLARGGGIRSTMQATATAGVEELAQLAHPRLAALLHSGATTIEVKSGYGLDFGAELRMLKAV
RALQESLPATLVPTLLIHVPPTESRAAYVRAVCEALIPEVARKRLAAAVDVFCEREAFTVEETRALFAAARSNGLQVKLH
ADQFHALGGTELACAVEALSVDHLEASGEAQIEALAASETVATVLPGVTLHLGLRAAPARRLVDAGACVAVGTDLNPGSS
PLFSAQLALALAVRLNGLTPAEALTACTVNAAAALGLRDRGALVAGQRADLLALHASDWRDLAYTLGANPVRDVFVGGQN
IKETLSKEKAL

Sequences:

>Translated_411_residues
MAELLLTGITQLVTPPPGPQRGAAMRKLTVLQDAALLMRDGMIAWVGSRQEAPAAAQIRDLGGVAVVPGLVDPHTHAVWA
GDRLADFEARVEGVPYEELLARGGGIRSTMQATATAGVEELAQLAHPRLAALLHSGATTIEVKSGYGLDFGAELRMLKAV
RALQESLPATLVPTLLIHVPPTESRAAYVRAVCEALIPEVARKRLAAAVDVFCEREAFTVEETRALFAAARSNGLQVKLH
ADQFHALGGTELACAVEALSVDHLEASGEAQIEALAASETVATVLPGVTLHLGLRAAPARRLVDAGACVAVGTDLNPGSS
PLFSAQLALALAVRLNGLTPAEALTACTVNAAAALGLRDRGALVAGQRADLLALHASDWRDLAYTLGANPVRDVFVGGQN
IKETLSKEKAL
>Mature_410_residues
AELLLTGITQLVTPPPGPQRGAAMRKLTVLQDAALLMRDGMIAWVGSRQEAPAAAQIRDLGGVAVVPGLVDPHTHAVWAG
DRLADFEARVEGVPYEELLARGGGIRSTMQATATAGVEELAQLAHPRLAALLHSGATTIEVKSGYGLDFGAELRMLKAVR
ALQESLPATLVPTLLIHVPPTESRAAYVRAVCEALIPEVARKRLAAAVDVFCEREAFTVEETRALFAAARSNGLQVKLHA
DQFHALGGTELACAVEALSVDHLEASGEAQIEALAASETVATVLPGVTLHLGLRAAPARRLVDAGACVAVGTDLNPGSSP
LFSAQLALALAVRLNGLTPAEALTACTVNAAAALGLRDRGALVAGQRADLLALHASDWRDLAYTLGANPVRDVFVGGQNI
KETLSKEKAL

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=398, Percent_Identity=32.9145728643216, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17555004, Length=405, Percent_Identity=29.3827160493827, Blast_Score=191, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 42854; Mature: 42723

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELLLTGITQLVTPPPGPQRGAAMRKLTVLQDAALLMRDGMIAWVGSRQEAPAAAQIRD
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
LGGVAVVPGLVDPHTHAVWAGDRLADFEARVEGVPYEELLARGGGIRSTMQATATAGVEE
CCCEEEECCCCCCCCCEEECCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHH
LAQLAHPRLAALLHSGATTIEVKSGYGLDFGAELRMLKAVRALQESLPATLVPTLLIHVP
HHHHHCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEEECC
PTESRAAYVRAVCEALIPEVARKRLAAAVDVFCEREAFTVEETRALFAAARSNGLQVKLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEE
ADQFHALGGTELACAVEALSVDHLEASGEAQIEALAASETVATVLPGVTLHLGLRAAPAR
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCEEEECCCCCCHH
RLVDAGACVAVGTDLNPGSSPLFSAQLALALAVRLNGLTPAEALTACTVNAAAALGLRDR
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GALVAGQRADLLALHASDWRDLAYTLGANPVRDVFVGGQNIKETLSKEKAL
CCEEECCCCCEEEEECCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AELLLTGITQLVTPPPGPQRGAAMRKLTVLQDAALLMRDGMIAWVGSRQEAPAAAQIRD
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
LGGVAVVPGLVDPHTHAVWAGDRLADFEARVEGVPYEELLARGGGIRSTMQATATAGVEE
CCCEEEECCCCCCCCCEEECCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHH
LAQLAHPRLAALLHSGATTIEVKSGYGLDFGAELRMLKAVRALQESLPATLVPTLLIHVP
HHHHHCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEEECC
PTESRAAYVRAVCEALIPEVARKRLAAAVDVFCEREAFTVEETRALFAAARSNGLQVKLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEE
ADQFHALGGTELACAVEALSVDHLEASGEAQIEALAASETVATVLPGVTLHLGLRAAPAR
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCEEEECCCCCCHH
RLVDAGACVAVGTDLNPGSSPLFSAQLALALAVRLNGLTPAEALTACTVNAAAALGLRDR
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
GALVAGQRADLLALHASDWRDLAYTLGANPVRDVFVGGQNIKETLSKEKAL
CCEEECCCCCEEEEECCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA