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The map label for this gene is acdA [H]

Identifier: 94312734

GI number: 94312734

Start: 344928

End: 346037

Strand: Direct

Name: acdA [H]

Synonym: Rmet_3804

Alternate gene names: 94312734

Gene position: 344928-346037 (Clockwise)

Preceding gene: 94312733

Following gene: 94312735

Centisome position: 13.37

GC content: 67.75

Gene sequence:

>1110_bases
ATGGATTTCACGTATAGCGAAGAACAGCGGATGCTCGCCGACAGCCTGCGCCGCTTTGTCGAATCCGAGTACTCCTTCGA
GAAGCGCCGCCGCAACGCCCGCGAACACGGCAGCTTCGACCGGGGCATCTGGTCGTCGCTGGCGGAGATGGGCGTGCTCG
GTCTGGCCGTGCCGGCTGACCACGGTGGCTTTGGCCACGGCCCGGCCAGCCAGGTTGTCGTGCAGCGCGAACTGGGCCGC
GCGCTCGTGCAGGAGCCTGTGATCCCGAGCGGTGTCATCGCCACGGCGATCCTCGCGCATCACGCGCCTGCTGCCCTGCA
GGCCGAGTGGCTGCCCGCCATCGCGAGTGGCGACAAGATCTTCACGCTGGCCTATCTGGAGCCGGACTCGCGTTATCGCC
CCGAAGTCGCCAGGACGACGGCCCGCAAGGCCGGTGCCGACGGCTATGTGCTCAATGGCCGGAAGTCGGTGGTCTGGCAT
GGCGCGGCGGCTGATACGTACATTGTTTCGGCGATGCTCGACGGCGCGCTGGCGCTGTTCCTGGTGAGCCGCGACGCGAA
GGGGCTGGCGGTAACCGGCTATCCGACCATGGACCGACTGTCGGGCGCGGGCCTGCAACTCGCCGACGTGCCCGCCACGC
TGGTCACGACGAACGGTCTCGAGGCCCTGGAGCTTGGACTCGATCACGGCGTTGCCGCGCAATGCGCGGCGGCGGCCGGC
GCTATCGAACGGCTGATCGAGATCACCGCCGAGTACCTTGGCACCCGCAAGCAGTTCGGCAAGCCGCTGGCATCTTTCCA
GGCCCTTCAGCACCGCGTGGCCGACATGCTGCTGCAGAAGGAACTGGCGCTGTCGATGGCCTACGTGGCCGCGCAGGGCC
TCGATGCCACCGACGCGGCCGAGCGCCGCCGCAAGGTGTCCGCCGCGAAGGTCGTCACGGCCAAGGCCGCGCGCTTCGCC
GGCCAGCAGGCGGTGCAGTTGCACGGCGGCATGGGTATGACTGATGAACTGGAGGTTGGCGACTATTTCAAGGCGCTGAC
CATGGTAGACGTCCTGCTGGGCGATACCGACCTCCACCTGGAACGCTACGGCGAAGCCATGGCGGCCTGA

Upstream 100 bases:

>100_bases
ACGACATGCGCAAGACCACGATCTACGGTGGTTCGACCGAGGTTCAGAAGAACATCATCTCCAAGATGATCATCGGTTTC
TAGGCGAAAGGACGACAAGC

Downstream 100 bases:

>100_bases
CAAGACCCGATAACGGATGACTGTTCATGACCATCAATAGCAAGGCATATATCGTCGGGGCGTACGAGCACCCGACCCGC
AAGGCACCGGACAAGACCGT

Product: putative acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MDFTYSEEQRMLADSLRRFVESEYSFEKRRRNAREHGSFDRGIWSSLAEMGVLGLAVPADHGGFGHGPASQVVVQRELGR
ALVQEPVIPSGVIATAILAHHAPAALQAEWLPAIASGDKIFTLAYLEPDSRYRPEVARTTARKAGADGYVLNGRKSVVWH
GAAADTYIVSAMLDGALALFLVSRDAKGLAVTGYPTMDRLSGAGLQLADVPATLVTTNGLEALELGLDHGVAAQCAAAAG
AIERLIEITAEYLGTRKQFGKPLASFQALQHRVADMLLQKELALSMAYVAAQGLDATDAAERRRKVSAAKVVTAKAARFA
GQQAVQLHGGMGMTDELEVGDYFKALTMVDVLLGDTDLHLERYGEAMAA

Sequences:

>Translated_369_residues
MDFTYSEEQRMLADSLRRFVESEYSFEKRRRNAREHGSFDRGIWSSLAEMGVLGLAVPADHGGFGHGPASQVVVQRELGR
ALVQEPVIPSGVIATAILAHHAPAALQAEWLPAIASGDKIFTLAYLEPDSRYRPEVARTTARKAGADGYVLNGRKSVVWH
GAAADTYIVSAMLDGALALFLVSRDAKGLAVTGYPTMDRLSGAGLQLADVPATLVTTNGLEALELGLDHGVAAQCAAAAG
AIERLIEITAEYLGTRKQFGKPLASFQALQHRVADMLLQKELALSMAYVAAQGLDATDAAERRRKVSAAKVVTAKAARFA
GQQAVQLHGGMGMTDELEVGDYFKALTMVDVLLGDTDLHLERYGEAMAA
>Mature_369_residues
MDFTYSEEQRMLADSLRRFVESEYSFEKRRRNAREHGSFDRGIWSSLAEMGVLGLAVPADHGGFGHGPASQVVVQRELGR
ALVQEPVIPSGVIATAILAHHAPAALQAEWLPAIASGDKIFTLAYLEPDSRYRPEVARTTARKAGADGYVLNGRKSVVWH
GAAADTYIVSAMLDGALALFLVSRDAKGLAVTGYPTMDRLSGAGLQLADVPATLVTTNGLEALELGLDHGVAAQCAAAAG
AIERLIEITAEYLGTRKQFGKPLASFQALQHRVADMLLQKELALSMAYVAAQGLDATDAAERRRKVSAAKVVTAKAARFA
GQQAVQLHGGMGMTDELEVGDYFKALTMVDVLLGDTDLHLERYGEAMAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=391, Percent_Identity=24.0409207161125, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=27.9452054794521, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=25.9259259259259, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=24.2937853107345, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=26.9541778975741, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4501857, Length=366, Percent_Identity=25.6830601092896, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=27.0341207349081, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=24.4186046511628, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=24.4186046511628, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI7669494, Length=348, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7656849, Length=342, Percent_Identity=24.8538011695906, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4557231, Length=410, Percent_Identity=23.1707317073171, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI187960098, Length=408, Percent_Identity=23.0392156862745, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=358, Percent_Identity=24.0223463687151, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786223, Length=389, Percent_Identity=22.879177377892, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=397, Percent_Identity=24.9370277078086, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=25.4957507082153, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=24.6031746031746, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=327, Percent_Identity=25.0764525993884, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=24.4623655913978, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=22.6063829787234, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=24.0208877284595, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=368, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=25.3369272237197, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=25, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=25.5874673629243, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=25.201072386059, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=24.2819843342037, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=23.2, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=398, Percent_Identity=24.1206030150754, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 39464; Mature: 39464

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTYSEEQRMLADSLRRFVESEYSFEKRRRNAREHGSFDRGIWSSLAEMGVLGLAVPAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHEEEECCC
HGGFGHGPASQVVVQRELGRALVQEPVIPSGVIATAILAHHAPAALQAEWLPAIASGDKI
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
FTLAYLEPDSRYRPEVARTTARKAGADGYVLNGRKSVVWHGAAADTYIVSAMLDGALALF
EEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
LVSRDAKGLAVTGYPTMDRLSGAGLQLADVPATLVTTNGLEALELGLDHGVAAQCAAAAG
HEECCCCCEEEECCCCHHHHCCCCCEEECCCEEEEECCCHHHHHHCCCCCHHHHHHHHHH
AIERLIEITAEYLGTRKQFGKPLASFQALQHRVADMLLQKELALSMAYVAAQGLDATDAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ERRRKVSAAKVVTAKAARFAGQQAVQLHGGMGMTDELEVGDYFKALTMVDVLLGDTDLHL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
ERYGEAMAA
HHHHHHHCC
>Mature Secondary Structure
MDFTYSEEQRMLADSLRRFVESEYSFEKRRRNAREHGSFDRGIWSSLAEMGVLGLAVPAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHEEEECCC
HGGFGHGPASQVVVQRELGRALVQEPVIPSGVIATAILAHHAPAALQAEWLPAIASGDKI
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEE
FTLAYLEPDSRYRPEVARTTARKAGADGYVLNGRKSVVWHGAAADTYIVSAMLDGALALF
EEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHH
LVSRDAKGLAVTGYPTMDRLSGAGLQLADVPATLVTTNGLEALELGLDHGVAAQCAAAAG
HEECCCCCEEEECCCCHHHHCCCCCEEECCCEEEEECCCHHHHHHCCCCCHHHHHHHHHH
AIERLIEITAEYLGTRKQFGKPLASFQALQHRVADMLLQKELALSMAYVAAQGLDATDAA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ERRRKVSAAKVVTAKAARFAGQQAVQLHGGMGMTDELEVGDYFKALTMVDVLLGDTDLHL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
ERYGEAMAA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]