The gene/protein map for NC_007974 is currently unavailable.
Definition Cupriavidus metallidurans CH34 megaplasmid, complete sequence.
Accession NC_007974
Length 2,580,084

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The map label for this gene is paaG [C]

Identifier: 94312730

GI number: 94312730

Start: 340060

End: 340923

Strand: Direct

Name: paaG [C]

Synonym: Rmet_3800

Alternate gene names: 94312730

Gene position: 340060-340923 (Clockwise)

Preceding gene: 94312728

Following gene: 94312733

Centisome position: 13.18

GC content: 65.05

Gene sequence:

>864_bases
ATGCAAATGGCGGGATGGCCAAGGATCGGCCAAGCTGACCGTGGTAGACGAAAAAAGGAGACAGGCATGACAGAAGAAGA
CGGCTTGCTGGTGGCAATCTCGGATGGCGTGGCAACGCTGACGCTCAACCGTCCGAAGCAGAAGAACGCCCTGAACGGTT
CCATGCGCGACGGGCTATGCGACGCAGTACAGCGGATTCGCGCCGACCGCTCGGTGCGCGCCGTAGTGTTGCGCGGCGCA
GGCGAGGACTTCTGCTCCGGTGGCGACATCCGCGCGATGAACGTGACGGAGGCGGACGCGGGCCGCGCGCGCATGGACGA
CATGCATGGCTGGATCGCCATGCTGCTGGATCTGGATCGTCCCGTGGTCGCGGCGGTCGATGGGGTGGCCTATGGGGCCG
GCTTCAGTATTGCGCTGCTTGCCGATTTCATCGTGGCGTCGCCGCGCGCGCGCTTCTGCATGCCGTTCATGAAAGTTGGC
CTGGTGCCCGATTGCGGCGCGCTATACACGCTGCCGAGAGTGGTAGGCATGGCGAAAGCGCGGGAACTGGTGTTTAGCGC
GCGCGAAATTGGCGCGGAGGAAGCGCGCCAGATTGGCGCCGTGTTCGAGATCGTGCCGGAAGACAAGCTCCATGCCCGCG
CCGACGAACTGGCTCGTGGTCTGGCCGGCGCTTCGCCGGCTGCATTCGCCATGGCCAAACGCGCGTTGAACCAGTCGCTT
GGCAGCGACGTGCGTGCCATGCTGGAAATGGAGTCGCTGGGGCAGGGCATCGCCTTCACTACCAGCTACCACCGCGAAGC
TGTGCGCCGCTTCAAGGAGAAGGAGCCGCCGCTGTTCCGCTGGCCTGCGGCGCCTCGGGACTGA

Upstream 100 bases:

>100_bases
CTCCAGAATAGTCAGCGATTATCCCCCCAACGGGCCCATTCGATCTATTCGCGCAACTACGGGGGGGTACTTCCGCGCAG
GCGAACGCAGGATTCAAAAC

Downstream 100 bases:

>100_bases
TCTCGGGGCTGATGGCTGCCGGGGGCATCGCCCCCGGTTTCACGTCGCCCTCCAGGTCATCCGTCACCCAGCCGTAATGC
CGGCTGTCTGGATGACCTTC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MQMAGWPRIGQADRGRRKKETGMTEEDGLLVAISDGVATLTLNRPKQKNALNGSMRDGLCDAVQRIRADRSVRAVVLRGA
GEDFCSGGDIRAMNVTEADAGRARMDDMHGWIAMLLDLDRPVVAAVDGVAYGAGFSIALLADFIVASPRARFCMPFMKVG
LVPDCGALYTLPRVVGMAKARELVFSAREIGAEEARQIGAVFEIVPEDKLHARADELARGLAGASPAAFAMAKRALNQSL
GSDVRAMLEMESLGQGIAFTTSYHREAVRRFKEKEPPLFRWPAAPRD

Sequences:

>Translated_287_residues
MQMAGWPRIGQADRGRRKKETGMTEEDGLLVAISDGVATLTLNRPKQKNALNGSMRDGLCDAVQRIRADRSVRAVVLRGA
GEDFCSGGDIRAMNVTEADAGRARMDDMHGWIAMLLDLDRPVVAAVDGVAYGAGFSIALLADFIVASPRARFCMPFMKVG
LVPDCGALYTLPRVVGMAKARELVFSAREIGAEEARQIGAVFEIVPEDKLHARADELARGLAGASPAAFAMAKRALNQSL
GSDVRAMLEMESLGQGIAFTTSYHREAVRRFKEKEPPLFRWPAAPRD
>Mature_287_residues
MQMAGWPRIGQADRGRRKKETGMTEEDGLLVAISDGVATLTLNRPKQKNALNGSMRDGLCDAVQRIRADRSVRAVVLRGA
GEDFCSGGDIRAMNVTEADAGRARMDDMHGWIAMLLDLDRPVVAAVDGVAYGAGFSIALLADFIVASPRARFCMPFMKVG
LVPDCGALYTLPRVVGMAKARELVFSAREIGAEEARQIGAVFEIVPEDKLHARADELARGLAGASPAAFAMAKRALNQSL
GSDVRAMLEMESLGQGIAFTTSYHREAVRRFKEKEPPLFRWPAAPRD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=31.8548387096774, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4502327, Length=285, Percent_Identity=29.1228070175439, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI260274832, Length=232, Percent_Identity=29.3103448275862, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI45643119, Length=232, Percent_Identity=29.3103448275862, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI260275230, Length=232, Percent_Identity=29.3103448275862, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4757968, Length=205, Percent_Identity=29.7560975609756, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI49355787, Length=205, Percent_Identity=29.7560975609756, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI25453481, Length=278, Percent_Identity=25.5395683453237, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI51538573, Length=278, Percent_Identity=25.5395683453237, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4757966, Length=203, Percent_Identity=29.064039408867, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI51538581, Length=203, Percent_Identity=29.064039408867, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI37594469, Length=167, Percent_Identity=31.1377245508982, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI37594471, Length=167, Percent_Identity=31.1377245508982, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542718, Length=275, Percent_Identity=24.7272727272727, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI68989263, Length=176, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI70995211, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI221136756, Length=222, Percent_Identity=25.6756756756757, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI221136753, Length=222, Percent_Identity=25.6756756756757, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI213417737, Length=219, Percent_Identity=26.4840182648402, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157694516, Length=219, Percent_Identity=26.4840182648402, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116235487, Length=155, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787660, Length=255, Percent_Identity=34.9019607843137, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=35.1778656126482, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI221142681, Length=199, Percent_Identity=37.1859296482412, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=29.5275590551181, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790281, Length=181, Percent_Identity=27.6243093922652, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=24.0458015267176, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=32.5301204819277, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=32.6693227091633, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17540714, Length=242, Percent_Identity=28.5123966942149, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=222, Percent_Identity=26.1261261261261, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=199, Percent_Identity=30.6532663316583, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=28.8372093023256, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=27.6497695852535, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=157, Percent_Identity=31.8471337579618, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=157, Percent_Identity=31.8471337579618, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=174, Percent_Identity=25.8620689655172, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=218, Percent_Identity=24.3119266055046, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=32.7868852459016, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=32.7868852459016, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653139, Length=250, Percent_Identity=28, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21357171, Length=241, Percent_Identity=28.2157676348548, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654903, Length=196, Percent_Identity=30.1020408163265, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571730, Length=176, Percent_Identity=30.1136363636364, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571729, Length=176, Percent_Identity=30.1136363636364, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920382, Length=218, Percent_Identity=29.8165137614679, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=23.2283464566929, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650670, Length=263, Percent_Identity=25.0950570342205, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31104; Mature: 31104

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MQMAGWPRIGQADRGRRKKETGMTEEDGLLVAISDGVATLTLNRPKQKNALNGSMRDGLC
CCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCHHHHHH
DAVQRIRADRSVRAVVLRGAGEDFCSGGDIRAMNVTEADAGRARMDDMHGWIAMLLDLDR
HHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
PVVAAVDGVAYGAGFSIALLADFIVASPRARFCMPFMKVGLVPDCGALYTLPRVVGMAKA
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RELVFSAREIGAEEARQIGAVFEIVPEDKLHARADELARGLAGASPAAFAMAKRALNQSL
HHHHHHHHHHCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GSDVRAMLEMESLGQGIAFTTSYHREAVRRFKEKEPPLFRWPAAPRD
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MQMAGWPRIGQADRGRRKKETGMTEEDGLLVAISDGVATLTLNRPKQKNALNGSMRDGLC
CCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCHHHHHH
DAVQRIRADRSVRAVVLRGAGEDFCSGGDIRAMNVTEADAGRARMDDMHGWIAMLLDLDR
HHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
PVVAAVDGVAYGAGFSIALLADFIVASPRARFCMPFMKVGLVPDCGALYTLPRVVGMAKA
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RELVFSAREIGAEEARQIGAVFEIVPEDKLHARADELARGLAGASPAAFAMAKRALNQSL
HHHHHHHHHHCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GSDVRAMLEMESLGQGIAFTTSYHREAVRRFKEKEPPLFRWPAAPRD
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA