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The map label for this gene is cheA [H]

Identifier: 94312621

GI number: 94312621

Start: 228384

End: 230399

Strand: Direct

Name: cheA [H]

Synonym: Rmet_3689

Alternate gene names: 94312621

Gene position: 228384-230399 (Clockwise)

Preceding gene: 94312620

Following gene: 94312622

Centisome position: 8.85

GC content: 65.28

Gene sequence:

>2016_bases
ATGTCTGTCGATATCGATATCACGCAGTTCTACCAGACCTTCTTCGAGGAGGCGGAGGAACTGCTCGTACAAATGGAGCA
GCTGCTGCTCGAGGTGGATATCGAATCCCCCGATGCGGAAGCGCTCAACGCGATCTTCCGTGCCGCGCATTCGATCAAGG
GCGGCGCCGCGACGTTCGGCTTCACGGCGCTGACCGAAACCACGCACATCTTCGAGAATCTGCTGGACCGCACGCGTCGG
AGGGAACTAGCTCTCTCGCGCGTCATCATCGACACCTTTCTGGAAACCAAGGACGTGTTGCACGATCAGCTCAACGCCTA
CCGTAACGGCACCGAACCCGATCCGGAAACGCTGGCGCGCATTTGCGCCGTGCTGCAGCAACTGGCCCAGGAAGCCAGCG
GCGAGGCGGCACCCGCGCCTGCCGCCACACCGGCGCCAGTGGCTGCATCCGCGCCCGCTGCCGCACCGGCTGGCGGCAAT
CTCAAGGTGAGCCTGATCAAGGTATCGGCCGCCGACCAGGCCCTGCTGCGCGAGGAGCTTGCCAACCTGGGCGAGATCAC
CGGTCAACAGGAATCGGACGGCGACCTGATCATCTGGCTGAACAGCCAGTGCAGCCCCGACGACATCATCGCGGTCTGCT
GCTTTGTGATCGACGAGAAGCAGATCGCCGTGGAAACGGTAACGCCAGGTGAGGCACCGGCGGCACCGGTCGGTGCGCCG
ACGCCCGCGCCCGTAGCCGCGCCGGCAGCCGTCGCGCCTGTCGCGCCCGCCGCCGCACCGGTGGCTGCCAAGGAGAAAGA
AAAGGCCAAGCCCGCCGCCGCGCACAGTCCGGATGCCGGTTCGATCCGCGTGCCGACCGAGAAGGTCGACCAGATCATCA
ACCTCGTGGGCGAACTGGTCATCACGCAGTCGATGCTGGCGCAGACCGCGTCGTCGCTGGACCCGGTGCTGTTCGACCGC
CTGTTCTCCGGCATGGGCCAGCTCGAGCGCAACGCGCGCGATCTGCAGGAAGCGGTGATGTCCATCCGCATGATGCCGAT
GGACTACGTGTTCTCGCGCTTCCCGCGTCTGGTGCGCGACATGATGGGCAAGCTCGGCAAGCAGATCGATCTGGTCACGT
TCGGCAAGGCAACGGAACTGGACAAGGGCCTGATCGAGCGGATCATCGATCCGCTGACCCATCTGGTACGAAACAGTCTC
GACCACGGCATCGAAACACCAGAGAAGCGTATCGCCGCCGGCAAGGAGCCGACCGGACAACTGATCCTCTCCGCGCAGCA
CGCGGGTGGCAACATCGTCATCGAGGTGAGCGATGACGGCGCCGGCCTGAACCGCGAGCGCATCCTGGCCAAGGCGATGC
AGAACGGCCTGCCGGTCTCCGAGAGCATGCCCGACGACGAAGTCTGGCAGCTCATCTTCGCGCCGGGCTTCTCCACGGCC
GAAGTCATTACCGATGTCTCCGGCCGGGGCGTTGGCATGGACGTGGTCAAGCGGAACATCCAGGAGATGGGCGGCCACGT
GGAAATCAGCTCGCGCGCCGGGCTGGGCACCACCACCCGCATCGTGCTGCCGCTGACGCTGGCGATTCTGGACGGCATGT
CGGTACGCACTGGCGAAGAAACCTTCATCCTGCCGCTGAACTGCGTGATGGAGTCGCTGCAGCCGTTGGCCGACGACGTG
CACACCGCCGCCAACGGCGAGCGGGTGATGAACGTGCGCGGCGAATACCTGCCGCTGCTGGAACTGCACAAGGTCTTCAA
CGTGGCCAACGCGGTGCAGGAGCCCACGCAGGGTATCGCCGTGATCCTGGCGGCCGAAGGCAAGCGCTTCGCGCTGCTGG
TGGACCAGTTGATCGGGCAGCACCAGGTGGTGCTCAAGAACCTCGAGACCAACTATCGCAAGGTGCCGTGCATTTCCGCC
GCCACCATCCTCGGTGACGGCAGCGTGGCCCTGATCGTGGACGTCGGCGCGCTGCAGCGCACCGGTGTGCGCCGCCAGGC
CCCGATGGCCGCGTAG

Upstream 100 bases:

>100_bases
CGGCGCGGGCGAAAGCAAAGGCAAGGGCAAGGGGGAATGACGCGTGTCGCCTGAACAGGGCGGCGCATCTTCCAGGGCAA
TCTAGCGAGTCAGGACGACC

Downstream 100 bases:

>100_bases
TAATCGACAGCAAGGAGAACGGACATGGCCGGCATCGGACATATCGATACCCAGGGCAGCGAAGCCTCGGGTCAGGAGTA
CCTGGTCTTCACGCTGGGGA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSVDIDITQFYQTFFEEAEELLVQMEQLLLEVDIESPDAEALNAIFRAAHSIKGGAATFGFTALTETTHIFENLLDRTRR
RELALSRVIIDTFLETKDVLHDQLNAYRNGTEPDPETLARICAVLQQLAQEASGEAAPAPAATPAPVAASAPAAAPAGGN
LKVSLIKVSAADQALLREELANLGEITGQQESDGDLIIWLNSQCSPDDIIAVCCFVIDEKQIAVETVTPGEAPAAPVGAP
TPAPVAAPAAVAPVAPAAAPVAAKEKEKAKPAAAHSPDAGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFDR
LFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDMMGKLGKQIDLVTFGKATELDKGLIERIIDPLTHLVRNSL
DHGIETPEKRIAAGKEPTGQLILSAQHAGGNIVIEVSDDGAGLNRERILAKAMQNGLPVSESMPDDEVWQLIFAPGFSTA
EVITDVSGRGVGMDVVKRNIQEMGGHVEISSRAGLGTTTRIVLPLTLAILDGMSVRTGEETFILPLNCVMESLQPLADDV
HTAANGERVMNVRGEYLPLLELHKVFNVANAVQEPTQGIAVILAAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISA
ATILGDGSVALIVDVGALQRTGVRRQAPMAA

Sequences:

>Translated_671_residues
MSVDIDITQFYQTFFEEAEELLVQMEQLLLEVDIESPDAEALNAIFRAAHSIKGGAATFGFTALTETTHIFENLLDRTRR
RELALSRVIIDTFLETKDVLHDQLNAYRNGTEPDPETLARICAVLQQLAQEASGEAAPAPAATPAPVAASAPAAAPAGGN
LKVSLIKVSAADQALLREELANLGEITGQQESDGDLIIWLNSQCSPDDIIAVCCFVIDEKQIAVETVTPGEAPAAPVGAP
TPAPVAAPAAVAPVAPAAAPVAAKEKEKAKPAAAHSPDAGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFDR
LFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDMMGKLGKQIDLVTFGKATELDKGLIERIIDPLTHLVRNSL
DHGIETPEKRIAAGKEPTGQLILSAQHAGGNIVIEVSDDGAGLNRERILAKAMQNGLPVSESMPDDEVWQLIFAPGFSTA
EVITDVSGRGVGMDVVKRNIQEMGGHVEISSRAGLGTTTRIVLPLTLAILDGMSVRTGEETFILPLNCVMESLQPLADDV
HTAANGERVMNVRGEYLPLLELHKVFNVANAVQEPTQGIAVILAAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISA
ATILGDGSVALIVDVGALQRTGVRRQAPMAA
>Mature_670_residues
SVDIDITQFYQTFFEEAEELLVQMEQLLLEVDIESPDAEALNAIFRAAHSIKGGAATFGFTALTETTHIFENLLDRTRRR
ELALSRVIIDTFLETKDVLHDQLNAYRNGTEPDPETLARICAVLQQLAQEASGEAAPAPAATPAPVAASAPAAAPAGGNL
KVSLIKVSAADQALLREELANLGEITGQQESDGDLIIWLNSQCSPDDIIAVCCFVIDEKQIAVETVTPGEAPAAPVGAPT
PAPVAAPAAVAPVAPAAAPVAAKEKEKAKPAAAHSPDAGSIRVPTEKVDQIINLVGELVITQSMLAQTASSLDPVLFDRL
FSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDMMGKLGKQIDLVTFGKATELDKGLIERIIDPLTHLVRNSLD
HGIETPEKRIAAGKEPTGQLILSAQHAGGNIVIEVSDDGAGLNRERILAKAMQNGLPVSESMPDDEVWQLIFAPGFSTAE
VITDVSGRGVGMDVVKRNIQEMGGHVEISSRAGLGTTTRIVLPLTLAILDGMSVRTGEETFILPLNCVMESLQPLADDVH
TAANGERVMNVRGEYLPLLELHKVFNVANAVQEPTQGIAVILAAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAA
TILGDGSVALIVDVGALQRTGVRRQAPMAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=670, Percent_Identity=62.2388059701493, Blast_Score=791, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71681; Mature: 71550

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDIDITQFYQTFFEEAEELLVQMEQLLLEVDIESPDAEALNAIFRAAHSIKGGAATFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FTALTETTHIFENLLDRTRRRELALSRVIIDTFLETKDVLHDQLNAYRNGTEPDPETLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEASGEAAPAPAATPAPVAASAPAAAPAGGNLKVSLIKVSAADQALLREEL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHH
ANLGEITGQQESDGDLIIWLNSQCSPDDIIAVCCFVIDEKQIAVETVTPGEAPAAPVGAP
HHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
TPAPVAAPAAVAPVAPAAAPVAAKEKEKAKPAAAHSPDAGSIRVPTEKVDQIINLVGELV
CCCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
ITQSMLAQTASSLDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MMGKLGKQIDLVTFGKATELDKGLIERIIDPLTHLVRNSLDHGIETPEKRIAAGKEPTGQ
HHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LILSAQHAGGNIVIEVSDDGAGLNRERILAKAMQNGLPVSESMPDDEVWQLIFAPGFSTA
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHH
EVITDVSGRGVGMDVVKRNIQEMGGHVEISSRAGLGTTTRIVLPLTLAILDGMSVRTGEE
HHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCC
TFILPLNCVMESLQPLADDVHTAANGERVMNVRGEYLPLLELHKVFNVANAVQEPTQGIA
EEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VILAAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQR
EEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHHH
TGVRRQAPMAA
CCCCCCCCCCC
>Mature Secondary Structure 
SVDIDITQFYQTFFEEAEELLVQMEQLLLEVDIESPDAEALNAIFRAAHSIKGGAATFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FTALTETTHIFENLLDRTRRRELALSRVIIDTFLETKDVLHDQLNAYRNGTEPDPETLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEASGEAAPAPAATPAPVAASAPAAAPAGGNLKVSLIKVSAADQALLREEL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHH
ANLGEITGQQESDGDLIIWLNSQCSPDDIIAVCCFVIDEKQIAVETVTPGEAPAAPVGAP
HHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
TPAPVAAPAAVAPVAPAAAPVAAKEKEKAKPAAAHSPDAGSIRVPTEKVDQIINLVGELV
CCCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHH
ITQSMLAQTASSLDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MMGKLGKQIDLVTFGKATELDKGLIERIIDPLTHLVRNSLDHGIETPEKRIAAGKEPTGQ
HHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LILSAQHAGGNIVIEVSDDGAGLNRERILAKAMQNGLPVSESMPDDEVWQLIFAPGFSTA
EEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHH
EVITDVSGRGVGMDVVKRNIQEMGGHVEISSRAGLGTTTRIVLPLTLAILDGMSVRTGEE
HHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCC
TFILPLNCVMESLQPLADDVHTAANGERVMNVRGEYLPLLELHKVFNVANAVQEPTQGIA
EEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VILAAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQR
EEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHHH
TGVRRQAPMAA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]