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The map label for this gene is cheW [H]

Identifier: 94312622

GI number: 94312622

Start: 230424

End: 230918

Strand: Direct

Name: cheW [H]

Synonym: Rmet_3690

Alternate gene names: 94312622

Gene position: 230424-230918 (Clockwise)

Preceding gene: 94312621

Following gene: 94312623

Centisome position: 8.93

GC content: 61.62

Gene sequence:

>495_bases
ATGGCCGGCATCGGACATATCGATACCCAGGGCAGCGAAGCCTCGGGTCAGGAGTACCTGGTCTTCACGCTGGGGACGGA
AGAATATGGCATCGACATCCTCAAAGTGCAGGAGATCCGCAGCTACGAGACGGTGACGCGCATCGCCAACGCGCCAGACT
TCCTCAAGGGCGTGACCAACCTGCGCGGCGTGATCGTGCCGATCGTCGACCTGCGCCTGAAGTTCAAGCTCGGCAACGTG
CGCTATGACCACCAGACCGTGGTGATCATCCTGAACGTGGCCGGCCGCGTGGTTGGCATCGTCGTCGACGGCGTATCGGA
CGTGCTGACGCTCACTGGCGATGACATCAAGCCCGCGCCGGAGTTCGGCGTGTCGGTCTCCAACGAACATCTGACCGGGC
TGGGTTCGGTGGAAGGCCGGATGCTGATCCTGATCGACATCGAACGCATGATGACCAGCCCAGAGATGGAATTGATCGAG
GCCGAGCTCGCCTGA

Upstream 100 bases:

>100_bases
CAGCGTGGCCCTGATCGTGGACGTCGGCGCGCTGCAGCGCACCGGTGTGCGCCGCCAGGCCCCGATGGCCGCGTAGTAAT
CGACAGCAAGGAGAACGGAC

Downstream 100 bases:

>100_bases
TGCTTGCCGGCACGTCCGGCAGCCCGCATCGCCGACTCCCCGGTACCTTGAAGGACATACACCATGACGCCGCTCCGTTC
TTCCTCCAGCGCCATCAGGA

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MAGIGHIDTQGSEASGQEYLVFTLGTEEYGIDILKVQEIRSYETVTRIANAPDFLKGVTNLRGVIVPIVDLRLKFKLGNV
RYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGDDIKPAPEFGVSVSNEHLTGLGSVEGRMLILIDIERMMTSPEMELIE
AELA

Sequences:

>Translated_164_residues
MAGIGHIDTQGSEASGQEYLVFTLGTEEYGIDILKVQEIRSYETVTRIANAPDFLKGVTNLRGVIVPIVDLRLKFKLGNV
RYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGDDIKPAPEFGVSVSNEHLTGLGSVEGRMLILIDIERMMTSPEMELIE
AELA
>Mature_163_residues
AGIGHIDTQGSEASGQEYLVFTLGTEEYGIDILKVQEIRSYETVTRIANAPDFLKGVTNLRGVIVPIVDLRLKFKLGNVR
YDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGDDIKPAPEFGVSVSNEHLTGLGSVEGRMLILIDIERMMTSPEMELIEA
ELA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=161, Percent_Identity=65.2173913043478, Blast_Score=214, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17809; Mature: 17678

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIGHIDTQGSEASGQEYLVFTLGTEEYGIDILKVQEIRSYETVTRIANAPDFLKGVTN
CCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHH
LRGVIVPIVDLRLKFKLGNVRYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGDDIKPAP
CCEEEEEEEEEEEEEEECCEEECCEEEEEEEECCCEEEEEEECCCCCEEEECCCCCCCCC
EFGVSVSNEHLTGLGSVEGRMLILIDIERMMTSPEMELIEAELA
CCCCEECCCCEEEECCCCCCEEEEEEEHHHHCCCCHHHHEEECC
>Mature Secondary Structure 
AGIGHIDTQGSEASGQEYLVFTLGTEEYGIDILKVQEIRSYETVTRIANAPDFLKGVTN
CCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHH
LRGVIVPIVDLRLKFKLGNVRYDHQTVVIILNVAGRVVGIVVDGVSDVLTLTGDDIKPAP
CCEEEEEEEEEEEEEEECCEEECCEEEEEEEECCCEEEEEEECCCCCEEEECCCCCCCCC
EFGVSVSNEHLTGLGSVEGRMLILIDIERMMTSPEMELIEAELA
CCCCEECCCCEEEECCCCCCEEEEEEEHHHHCCCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]