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The map label for this gene is aer [H]

Identifier: 94312614

GI number: 94312614

Start: 220629

End: 222287

Strand: Direct

Name: aer [H]

Synonym: Rmet_3682

Alternate gene names: 94312614

Gene position: 220629-222287 (Clockwise)

Preceding gene: 94312613

Following gene: 94312615

Centisome position: 8.55

GC content: 67.33

Gene sequence:

>1659_bases
ATGCGCAACAACCAGCCAGTCACCCAGCGGGAGCATCCGCTTCCCCCGGACGTCTACCTGATCTCGCGAACCGACCTCAA
GGGTCGTATCACGTTCGCCAATCGGACGTTCGTCGAGGTGAGCGGATTCACGTCCGACGAGCTGCTTGGCGCTGCCCACA
ATCTCGTGCGACATCCCGACATGCCGCCCGAGGCCTTTGCCGATCTCTGGGATTCGCTGCAGGCGGGCAAGTCATGGGTG
GGCGTTGTGAAGAATCGCTGCAAGAACGGCGATCACTACTGGGTGCAGGCCACGGTCACGCCGACACGCGTCGGCGACCG
CGTCGTCGGCTATACGTCGGTGCGCTCGATGGCCAGCCGCGAACAGATCGGCGCGGCCGACGCCGCATATCGGCGCTTCC
GCGAGAACCGGGCCGGCGGCCTGGCGATTCGCGATGGCGCCGTGGTGCGTACTGGCCTGGCAGGTCTGGTTGGCCGCGTG
ACGCGGATTACCCTGAAGCGACGCATCCTCTGGGCCCAGCTTGCGGGGCTGGTGTGGTTCCTGGCGGCTATCGCCGGCGT
GCACTGGCTGGCAGAGGAGCAGGCCGCGCAACTCTGGCCGTGGCTGTGGGGCGCATTTGGATTCGCGGTGCTCTCCTCGT
TCATGGCGGGTTCGATGCTGGTGTCGCGTGTCGAGCGCCCGGTGCGCGAGATGCTGGACTTCGCGCTGCGTATGGGCGCG
GGCGATCTGACGAGCAACTTCGAACACCGGTCAGCCGACGAAGTCGGCGAACTGTCGCGTGCCATGCGCACGATGCAGCG
CAGCCTGCAGTCGGTGGTCAACGATATCCAGGGCGGCATGGCCAGCATCTCGGCGGCCACGCACCAGGTGGCCGCCGGCA
ACAACGATCTCTCGCAGCGTACCGAGCAGCAGGCGGCGTCGCTCGAGGAAACGGCTTCGAGCATGGAGCAGCTGACCAGC
ACGGTCCGGCAGAACGCCGACAACGCGCACCAGGCCACGCGGCTGGCGGCCGATGCCTCCGAGACGGCCGTGCGCGGCGG
TGAGGCGGTGGGGCGCGTGGTCCAGACGATGGACGAGATCAACGAGGCCTCGCGCAAGATCGTCGACATCATCGGCGTGA
TCGAGGGCATCGCGTTCCAGACCAACATCCTGGCGCTGAACGCGGCGGTGGAAGCGGCGCGCGCGGCCGAGCAGGGCCGC
GGATTCGCGGTGGTGGCCGGCGAGGTGCGCAGCCTGGCGCAGCGCAGCGCCAATGCGGCCAAGGAGATCAAGGGGCTGAT
TGGCAATACCGTGGCGCGCGTGGAAAGCGGCGCGGAACAGGTGAGTCAGGCTGGCGCCACGATGGACGAGATCGTGCAGG
CCGTGAAGCGCGTGACCGACATCATGGGTGAGATCAGTTCGGCATCGGCGGAACAGAGCGCAGGCATCGAGCAGGTGAAT
GAGGCGGTGACGCAGATGGACGATGTGACGCAGCAGAACGCTGCGCTGGTGGAGCAGGCCGCTGCCGCGGCGGGCTCGCT
CGAAGAACAGGCCGAGCGCCTGCGGGAGTCGATCTCCACGTTCCGCGTGAGTATGCAGGCCGAGGTTCGGCCGCCGCGCA
AGCGACAGGTGGCGACGATGGGTGAAACGGGGAAAGAAGCCGGGCTGGTCAACGCCTGA

Upstream 100 bases:

>100_bases
AGCGCTCCGCGCCGGGTCGTATCTCGCCCCACGCGCGTCCTGCCGGGCGTGGCGTGGGCCGCCGCACACCGCGGTCAACG
CCCCCAAAGCAGTCAAAGCC

Downstream 100 bases:

>100_bases
GCTTCGGGTCTATTCAAATGGAAGGAGGGGGTAGTTCTATGCAGTGGTTCAATCAACTACGCGTGACAACCAGGCTGATT
GCTGGCTTCCTGGTTGTATC

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MRNNQPVTQREHPLPPDVYLISRTDLKGRITFANRTFVEVSGFTSDELLGAAHNLVRHPDMPPEAFADLWDSLQAGKSWV
GVVKNRCKNGDHYWVQATVTPTRVGDRVVGYTSVRSMASREQIGAADAAYRRFRENRAGGLAIRDGAVVRTGLAGLVGRV
TRITLKRRILWAQLAGLVWFLAAIAGVHWLAEEQAAQLWPWLWGAFGFAVLSSFMAGSMLVSRVERPVREMLDFALRMGA
GDLTSNFEHRSADEVGELSRAMRTMQRSLQSVVNDIQGGMASISAATHQVAAGNNDLSQRTEQQAASLEETASSMEQLTS
TVRQNADNAHQATRLAADASETAVRGGEAVGRVVQTMDEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAAEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGNTVARVESGAEQVSQAGATMDEIVQAVKRVTDIMGEISSASAEQSAGIEQVN
EAVTQMDDVTQQNAALVEQAAAAAGSLEEQAERLRESISTFRVSMQAEVRPPRKRQVATMGETGKEAGLVNA

Sequences:

>Translated_552_residues
MRNNQPVTQREHPLPPDVYLISRTDLKGRITFANRTFVEVSGFTSDELLGAAHNLVRHPDMPPEAFADLWDSLQAGKSWV
GVVKNRCKNGDHYWVQATVTPTRVGDRVVGYTSVRSMASREQIGAADAAYRRFRENRAGGLAIRDGAVVRTGLAGLVGRV
TRITLKRRILWAQLAGLVWFLAAIAGVHWLAEEQAAQLWPWLWGAFGFAVLSSFMAGSMLVSRVERPVREMLDFALRMGA
GDLTSNFEHRSADEVGELSRAMRTMQRSLQSVVNDIQGGMASISAATHQVAAGNNDLSQRTEQQAASLEETASSMEQLTS
TVRQNADNAHQATRLAADASETAVRGGEAVGRVVQTMDEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAAEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGNTVARVESGAEQVSQAGATMDEIVQAVKRVTDIMGEISSASAEQSAGIEQVN
EAVTQMDDVTQQNAALVEQAAAAAGSLEEQAERLRESISTFRVSMQAEVRPPRKRQVATMGETGKEAGLVNA
>Mature_552_residues
MRNNQPVTQREHPLPPDVYLISRTDLKGRITFANRTFVEVSGFTSDELLGAAHNLVRHPDMPPEAFADLWDSLQAGKSWV
GVVKNRCKNGDHYWVQATVTPTRVGDRVVGYTSVRSMASREQIGAADAAYRRFRENRAGGLAIRDGAVVRTGLAGLVGRV
TRITLKRRILWAQLAGLVWFLAAIAGVHWLAEEQAAQLWPWLWGAFGFAVLSSFMAGSMLVSRVERPVREMLDFALRMGA
GDLTSNFEHRSADEVGELSRAMRTMQRSLQSVVNDIQGGMASISAATHQVAAGNNDLSQRTEQQAASLEETASSMEQLTS
TVRQNADNAHQATRLAADASETAVRGGEAVGRVVQTMDEINEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAAEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGNTVARVESGAEQVSQAGATMDEIVQAVKRVTDIMGEISSASAEQSAGIEQVN
EAVTQMDDVTQQNAALVEQAAAAAGSLEEQAERLRESISTFRVSMQAEVRPPRKRQVATMGETGKEAGLVNA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=528, Percent_Identity=39.0151515151515, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=53.1531531531532, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI2367378, Length=322, Percent_Identity=59.6273291925466, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=58.3061889250814, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=55.4455445544555, Blast_Score=294, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59458; Mature: 59458

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS00041 HTH_ARAC_FAMILY_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTQREHPLPPDVYLISRTDLKGRITFANRTFVEVSGFTSDELLGAAHNLVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCC
MPPEAFADLWDSLQAGKSWVGVVKNRCKNGDHYWVQATVTPTRVGDRVVGYTSVRSMASR
CCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEEECHHHHCCHHHHHHHHHHHHHH
EQIGAADAAYRRFRENRAGGLAIRDGAVVRTGLAGLVGRVTRITLKRRILWAQLAGLVWF
HHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAGVHWLAEEQAAQLWPWLWGAFGFAVLSSFMAGSMLVSRVERPVREMLDFALRMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDLTSNFEHRSADEVGELSRAMRTMQRSLQSVVNDIQGGMASISAATHQVAAGNNDLSQR
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHH
TEQQAASLEETASSMEQLTSTVRQNADNAHQATRLAADASETAVRGGEAVGRVVQTMDEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHH
NEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAAEQGRGFAVVAGEVRSLAQRSANAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
KEIKGLIGNTVARVESGAEQVSQAGATMDEIVQAVKRVTDIMGEISSASAEQSAGIEQVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHH
EAVTQMDDVTQQNAALVEQAAAAAGSLEEQAERLRESISTFRVSMQAEVRPPRKRQVATM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GETGKEAGLVNA
CCCCCCCCCCCC
>Mature Secondary Structure
MRNNQPVTQREHPLPPDVYLISRTDLKGRITFANRTFVEVSGFTSDELLGAAHNLVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCC
MPPEAFADLWDSLQAGKSWVGVVKNRCKNGDHYWVQATVTPTRVGDRVVGYTSVRSMASR
CCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEEEECHHHHCCHHHHHHHHHHHHHH
EQIGAADAAYRRFRENRAGGLAIRDGAVVRTGLAGLVGRVTRITLKRRILWAQLAGLVWF
HHHCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAGVHWLAEEQAAQLWPWLWGAFGFAVLSSFMAGSMLVSRVERPVREMLDFALRMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDLTSNFEHRSADEVGELSRAMRTMQRSLQSVVNDIQGGMASISAATHQVAAGNNDLSQR
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHH
TEQQAASLEETASSMEQLTSTVRQNADNAHQATRLAADASETAVRGGEAVGRVVQTMDEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHH
NEASRKIVDIIGVIEGIAFQTNILALNAAVEAARAAEQGRGFAVVAGEVRSLAQRSANAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
KEIKGLIGNTVARVESGAEQVSQAGATMDEIVQAVKRVTDIMGEISSASAEQSAGIEQVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHH
EAVTQMDDVTQQNAALVEQAAAAAGSLEEQAERLRESISTFRVSMQAEVRPPRKRQVATM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GETGKEAGLVNA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]