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The map label for this gene is cheW [H]

Identifier: 94312613

GI number: 94312613

Start: 219960

End: 220511

Strand: Direct

Name: cheW [H]

Synonym: Rmet_3681

Alternate gene names: 94312613

Gene position: 219960-220511 (Clockwise)

Preceding gene: 94312612

Following gene: 94312614

Centisome position: 8.53

GC content: 61.78

Gene sequence:

>552_bases
ATGCGCGGTAACGGCAAGGGCACGCCAGCCCGGCAACGATCAACCATGCCAGCGGGGGCAACCATGAACATCAGCATCAA
CAGGACGGACGGTTCGGGAGAGGAATTCCTGGCGTTCCGGCTCGGTCGTGAAGAGTACGGTATCGACATCCTGAAAGTTC
AGGAGATTCGCGGCTACGAAACGGTGACGCAGATCGCCAATGCTCCCGCGTACCTGAAGGGCGTGATCAACCTGCGCGGC
ACGATCGTCCCGATCATCGACCTGCGCATCAAGTTCAATCAGGCCCAGATCAGCTACGACCAGTACACCGTCGTGATCAT
CGTCGACATCCATGAGCGGACCACCGGCATCGTGGTCGATGGCGTGTCGGACGTGCTGACGCTGGCCCCGGCCCAGATCA
AGCAGGCACCGACCCTGTCGGGCGGCGTCGAAACCGACTATATCCGTGGCATCGGCTCGCTCGAGGGCCGCATGCTGATC
CTGGCGGACATCGAAAAGTTGATGAACGTCGACGATCTCGCGGCCATCGAAGCCGCGGCTGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CAACGTAGGGTGAGTTTCACGCAAAGTCGCCCTTCATTCACCCCGCTGCCTGCCGTAATTACTAGAGGGCCATATTCGAT
GCCCGGTTTCAGGGGCCGCC

Downstream 100 bases:

>100_bases
GCGGCGCGAGCGGCCCGAGCGCTCCGCGCCGGGTCGTATCTCGCCCCACGCGCGTCCTGCCGGGCGTGGCGTGGGCCGCC
GCACACCGCGGTCAACGCCC

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MRGNGKGTPARQRSTMPAGATMNISINRTDGSGEEFLAFRLGREEYGIDILKVQEIRGYETVTQIANAPAYLKGVINLRG
TIVPIIDLRIKFNQAQISYDQYTVVIIVDIHERTTGIVVDGVSDVLTLAPAQIKQAPTLSGGVETDYIRGIGSLEGRMLI
LADIEKLMNVDDLAAIEAAAGAA

Sequences:

>Translated_183_residues
MRGNGKGTPARQRSTMPAGATMNISINRTDGSGEEFLAFRLGREEYGIDILKVQEIRGYETVTQIANAPAYLKGVINLRG
TIVPIIDLRIKFNQAQISYDQYTVVIIVDIHERTTGIVVDGVSDVLTLAPAQIKQAPTLSGGVETDYIRGIGSLEGRMLI
LADIEKLMNVDDLAAIEAAAGAA
>Mature_183_residues
MRGNGKGTPARQRSTMPAGATMNISINRTDGSGEEFLAFRLGREEYGIDILKVQEIRGYETVTQIANAPAYLKGVINLRG
TIVPIIDLRIKFNQAQISYDQYTVVIIVDIHERTTGIVVDGVSDVLTLAPAQIKQAPTLSGGVETDYIRGIGSLEGRMLI
LADIEKLMNVDDLAAIEAAAGAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=158, Percent_Identity=56.9620253164557, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19689; Mature: 19689

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGNGKGTPARQRSTMPAGATMNISINRTDGSGEEFLAFRLGREEYGIDILKVQEIRGYE
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCHHHCEEEEEEEECCCHH
TVTQIANAPAYLKGVINLRGTIVPIIDLRIKFNQAQISYDQYTVVIIVDIHERTTGIVVD
HHHHHHCCCHHEEEEEECCCEEEEEEEEEEEECCEEEEECCEEEEEEEEECCCCCEEEEE
GVSDVLTLAPAQIKQAPTLSGGVETDYIRGIGSLEGRMLILADIEKLMNVDDLAAIEAAA
CHHHHHHHCHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHC
GAA
CCC
>Mature Secondary Structure
MRGNGKGTPARQRSTMPAGATMNISINRTDGSGEEFLAFRLGREEYGIDILKVQEIRGYE
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCHHHCEEEEEEEECCCHH
TVTQIANAPAYLKGVINLRGTIVPIIDLRIKFNQAQISYDQYTVVIIVDIHERTTGIVVD
HHHHHHCCCHHEEEEEECCCEEEEEEEEEEEECCEEEEECCEEEEEEEEECCCCCEEEEE
GVSDVLTLAPAQIKQAPTLSGGVETDYIRGIGSLEGRMLILADIEKLMNVDDLAAIEAAA
CHHHHHHHCHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEEHHHHCCCCHHHHHHHHC
GAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]