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The map label for this gene is tig [H]

Identifier: 93007057

GI number: 93007057

Start: 2740538

End: 2741881

Strand: Direct

Name: tig [H]

Synonym: Pcryo_2233

Alternate gene names: 93007057

Gene position: 2740538-2741881 (Clockwise)

Preceding gene: 93007056

Following gene: 93007058

Centisome position: 89.56

GC content: 42.41

Gene sequence:

>1344_bases
ATGGCTACAGATTTACAAGTCACAACCAACAAGCTATCTAACAAAGAAACTCAGTTAACGGTTAAAGTACCCGTTGAAAA
GATTCAAAACAAAGTTGAAGGCCGTATTCGCCAAGTAGCGAAAACTGCCAAGATTGACGGTTTCCGTAAAGGTAACGTGC
CTATGTCACATATCCGTTCACAGTACGGTGCTGGCATTCAACAAGAAGTGATCAACGACGTCATCCGTGATACTGTATTT
GAAGCGATCAAATCTGAAGACATCCGCGCCGTTGGCATGCCGAATATCGACGACGTAAAACTTGAAGATGATTTCTTGGT
TTATCAAGCCACTGTTGAAATCTTCCCAGAAGTTGATGTACAAGGTATCAATGAGATCGAAGTTGAACGTCATACCGCCA
AGGTTGATGAAGCTGATGTTGACACCATGATCGAAAACCTACAAAAACAACGTGAAGAATTCGTTGAGAAAAAAGGTAAA
GCGGACAAAGGCAATCAAGTCACTTTTGACTTTGAAGGCTCTATCGATGGCGAAAAATTCGAAGGCGGTTCTGCTGAAGA
CTTCAAATTGGTTATCGGTAGCAATCAGATGATTCCTGGCTTTGAAGCAGGCATCAAAGGTATGAAAGCTGGCGAAGAAA
AAACCATCGACGTGACTTTCCCAGAAGATTATCAAGCTGAAAACTTAGCGGGTAAAGAAGCTCAGTTCAAAATCAATGTA
AAATTGGTTGAAAAATCTAAGCTACCAGAAATTGACGATGCATTCCTTGAGCTATTTGGTGTTAAAGAAGGCGGCGTTGA
GAAGTTAAAAGATGACGTTCGCAAAAACATGGAACGCGAAATCAAAAATGCTGCTCGTAGCCAAGTAAAGCAAGCAACGT
TTGATGCTTTGTTAGAAAAGAACGAGTTTGACGTACCTAATGCTATGCTAGAGCAAGAAATCGAGCGTCAACGCAACATG
ATGATGCAACGTTTTTCTCAGCAGTTCGGTGCGAATGCTGATAGCTTCGATAAAGACATGCTACCAAATGAGTTATTCGA
AGAGCAAGCACTACGTGCGGCACGCCTTGGCATCATCGTTGCTCGCGTTATCGATACCAAAGGCTTAGAAGTTGACCAAG
CTCGCGTTGAGACGTTCATCAAAGAAGCGGCTGAAAACTACGAAGATCCAAGTGAGGTAATCGAGTACTACACCACTGAT
AAGCAACAGCGCGCGAACATTGAGTCTGTTGTATTAGAAGACCAAGTGGTTGATTATCTAATCGAGCAAGGTAAAGTAAC
TGACAAAGAAGTTAGCTACCAAGACCTATTAGCTGCTCAGCAACAACAGCAGCAAGCAATGTAA

Upstream 100 bases:

>100_bases
TGCTATCACTATCCCCTATTTATTCCAACGGCAACCAGTCATAAACGCCCGTATTTTGAGGCATGGTTGTCTATTATTTA
ATCCTAAAGGTGTAATGATC

Downstream 100 bases:

>100_bases
TCTAGCTAAATCTTTGCCATTAACTGGTACTGACTGCTAAGATTGCTCTAAAAATGCCCTAACAAATTTGTTAGGGCATT
TTTATTGGTGGCTTATATGC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MATDLQVTTNKLSNKETQLTVKVPVEKIQNKVEGRIRQVAKTAKIDGFRKGNVPMSHIRSQYGAGIQQEVINDVIRDTVF
EAIKSEDIRAVGMPNIDDVKLEDDFLVYQATVEIFPEVDVQGINEIEVERHTAKVDEADVDTMIENLQKQREEFVEKKGK
ADKGNQVTFDFEGSIDGEKFEGGSAEDFKLVIGSNQMIPGFEAGIKGMKAGEEKTIDVTFPEDYQAENLAGKEAQFKINV
KLVEKSKLPEIDDAFLELFGVKEGGVEKLKDDVRKNMEREIKNAARSQVKQATFDALLEKNEFDVPNAMLEQEIERQRNM
MMQRFSQQFGANADSFDKDMLPNELFEEQALRAARLGIIVARVIDTKGLEVDQARVETFIKEAAENYEDPSEVIEYYTTD
KQQRANIESVVLEDQVVDYLIEQGKVTDKEVSYQDLLAAQQQQQQAM

Sequences:

>Translated_447_residues
MATDLQVTTNKLSNKETQLTVKVPVEKIQNKVEGRIRQVAKTAKIDGFRKGNVPMSHIRSQYGAGIQQEVINDVIRDTVF
EAIKSEDIRAVGMPNIDDVKLEDDFLVYQATVEIFPEVDVQGINEIEVERHTAKVDEADVDTMIENLQKQREEFVEKKGK
ADKGNQVTFDFEGSIDGEKFEGGSAEDFKLVIGSNQMIPGFEAGIKGMKAGEEKTIDVTFPEDYQAENLAGKEAQFKINV
KLVEKSKLPEIDDAFLELFGVKEGGVEKLKDDVRKNMEREIKNAARSQVKQATFDALLEKNEFDVPNAMLEQEIERQRNM
MMQRFSQQFGANADSFDKDMLPNELFEEQALRAARLGIIVARVIDTKGLEVDQARVETFIKEAAENYEDPSEVIEYYTTD
KQQRANIESVVLEDQVVDYLIEQGKVTDKEVSYQDLLAAQQQQQQAM
>Mature_446_residues
ATDLQVTTNKLSNKETQLTVKVPVEKIQNKVEGRIRQVAKTAKIDGFRKGNVPMSHIRSQYGAGIQQEVINDVIRDTVFE
AIKSEDIRAVGMPNIDDVKLEDDFLVYQATVEIFPEVDVQGINEIEVERHTAKVDEADVDTMIENLQKQREEFVEKKGKA
DKGNQVTFDFEGSIDGEKFEGGSAEDFKLVIGSNQMIPGFEAGIKGMKAGEEKTIDVTFPEDYQAENLAGKEAQFKINVK
LVEKSKLPEIDDAFLELFGVKEGGVEKLKDDVRKNMEREIKNAARSQVKQATFDALLEKNEFDVPNAMLEQEIERQRNMM
MQRFSQQFGANADSFDKDMLPNELFEEQALRAARLGIIVARVIDTKGLEVDQARVETFIKEAAENYEDPSEVIEYYTTDK
QQRANIESVVLEDQVVDYLIEQGKVTDKEVSYQDLLAAQQQQQQAM

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=438, Percent_Identity=44.0639269406393, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 50599; Mature: 50467

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDLQVTTNKLSNKETQLTVKVPVEKIQNKVEGRIRQVAKTAKIDGFRKGNVPMSHIRS
CCCCCEEHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QYGAGIQQEVINDVIRDTVFEAIKSEDIRAVGMPNIDDVKLEDDFLVYQATVEIFPEVDV
HHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEEEEEEHHHHCCCCCC
QGINEIEVERHTAKVDEADVDTMIENLQKQREEFVEKKGKADKGNQVTFDFEGSIDGEKF
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
EGGSAEDFKLVIGSNQMIPGFEAGIKGMKAGEEKTIDVTFPEDYQAENLAGKEAQFKINV
CCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
KLVEKSKLPEIDDAFLELFGVKEGGVEKLKDDVRKNMEREIKNAARSQVKQATFDALLEK
EEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEFDVPNAMLEQEIERQRNMMMQRFSQQFGANADSFDKDMLPNELFEEQALRAARLGIIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
ARVIDTKGLEVDQARVETFIKEAAENYEDPSEVIEYYTTDKQQRANIESVVLEDQVVDYL
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHH
IEQGKVTDKEVSYQDLLAAQQQQQQAM
HHCCCCCCHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATDLQVTTNKLSNKETQLTVKVPVEKIQNKVEGRIRQVAKTAKIDGFRKGNVPMSHIRS
CCCCEEHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QYGAGIQQEVINDVIRDTVFEAIKSEDIRAVGMPNIDDVKLEDDFLVYQATVEIFPEVDV
HHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEEEEEEHHHHCCCCCC
QGINEIEVERHTAKVDEADVDTMIENLQKQREEFVEKKGKADKGNQVTFDFEGSIDGEKF
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
EGGSAEDFKLVIGSNQMIPGFEAGIKGMKAGEEKTIDVTFPEDYQAENLAGKEAQFKINV
CCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
KLVEKSKLPEIDDAFLELFGVKEGGVEKLKDDVRKNMEREIKNAARSQVKQATFDALLEK
EEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEFDVPNAMLEQEIERQRNMMMQRFSQQFGANADSFDKDMLPNELFEEQALRAARLGIIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
ARVIDTKGLEVDQARVETFIKEAAENYEDPSEVIEYYTTDKQQRANIESVVLEDQVVDYL
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHH
IEQGKVTDKEVSYQDLLAAQQQQQQAM
HHCCCCCCHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA