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The map label for this gene is trpE [H]

Identifier: 93006747

GI number: 93006747

Start: 2373643

End: 2375061

Strand: Direct

Name: trpE [H]

Synonym: Pcryo_1923

Alternate gene names: 93006747

Gene position: 2373643-2375061 (Clockwise)

Preceding gene: 93006746

Following gene: 93006748

Centisome position: 77.57

GC content: 44.96

Gene sequence:

>1419_bases
ATGACCTCTCCTACACTACAATATGACCAGCCTGCTACTATTGATATTCCAAGCAAGCCGCAGCGGATAAAGCTGACGCA
AGATATTGATTTTTTCGCGTTATTTAAACGTATTGAACGGGTTTTCGATACCTGTTATTTGCTCGAATCCTTGGGTGAAG
ACAGCCATATGTCACGTCACCATGCCATTGGTTTTGATCCGGTGATGACCATTGCAGCCATCGACCGCACAACGCTTGCT
ATTACCGATAATAAAACCGCTGAAACCAAACATTATCAGACTGACAATCCTTATCAGCTTCTACGTACTATTACTCCGCA
GCACGTCATCGCCCGTGAGCAAAGTGGCGGTCTTGTCGGCTATCTAGGCTACGACTGTGTCAATTTCTTTGAGCCAAGTC
TAAATGCCAAGCCAAGCGATGATTTTGAACCTTTCAAATTTGGTGTCTATCTAGATGGCTTGACGCTCGATAAAATGACT
GGTGAAATTTTCTACTTTTACTATCCTACCGCTCAGCAAGACAATCGCATCGAGCAAATCAAAGCCTTACTTGATGTACC
TATCCCAAGCTATAAACCGCCCACCGTAGAGTTTTTAGGTGATGGTATGAGTCAAGAAGAGCATGCTAAAGTCGTCATGC
AAGTCAAAGAAGACATCATCTCTGGGCGTATTTTTCAATGTGAAGTCGGCTTTAAATCCAAATATCGTATTGCGGGCGAT
AAGATGCCAATTTATGAAAAGCTACGTGCGGTCAATCCATCACCGCATATGTATTTTATGAAATTTGCTCAGCAATGCAT
CATCGGTGCCTCACCTGAATTGCTATTTCGCTTGCGTCAGGGCGAGATGGAGACCTATCCGCTCGCAGGTACAGCCAAGC
GCGGTGTTGATGTTGCCGAAGATCGCAAACTTGCGCGTGCCCTGCTGAATGACGCAAAAGAGATTGCCGAGCACAATATG
CTAGTCGATCTGCATCGCAATGATATCGGACGCGTCGCACAATTTGGTACGGTAAAAGTGCGTAATCTGATGGATATCAA
ACGCTTCTCACACGTACAGCATATCTCCTCTGAAATCGTCGGTATTCTGCATCCTGATGAGGATATGTTTAGCGCACTTG
CCAGCAACTTCCCTGCTGGCACATTGTCAGGCGCACCAAAAGTTGAAGCGATAAAAGTGATTAATGAGCTTGAACCAGAT
GGTCGTGGTGCTTATGGCGGCGCATTAGGATCCTTTAACTTTAACGGCGATTGTATTTTTGCCATTCCTATTCGCAGCTT
ATTTATCAATGGTGAATCGGCCTATGCACAGACTTGTGGCGGCAATGTGTACGACTCCAATCCTGCTGATGAATATCTAG
AAATCCAGCGTAAGCTTTCTGCTATGAAAGTGGTACTAGACAGCTTTATGAACCCATAA

Upstream 100 bases:

>100_bases
GTAAGCGCACTGCTAGCCACCCACAGACAAGACAATTAACGCCAAGAATGTTAGCTGAATTTATTTTATAAGACCTATTT
GAATTACTTTGGACCTCATT

Downstream 100 bases:

>100_bases
CCACATATAATTTATCAAAGAGTTGGCCACCCATGAATGTTTTAATTATCGATAATTACGACTCATTTACTTTCAACCTT
TACCAGTATATCGGTGAGAT

Product: anthranilate synthase

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTSPTLQYDQPATIDIPSKPQRIKLTQDIDFFALFKRIERVFDTCYLLESLGEDSHMSRHHAIGFDPVMTIAAIDRTTLA
ITDNKTAETKHYQTDNPYQLLRTITPQHVIAREQSGGLVGYLGYDCVNFFEPSLNAKPSDDFEPFKFGVYLDGLTLDKMT
GEIFYFYYPTAQQDNRIEQIKALLDVPIPSYKPPTVEFLGDGMSQEEHAKVVMQVKEDIISGRIFQCEVGFKSKYRIAGD
KMPIYEKLRAVNPSPHMYFMKFAQQCIIGASPELLFRLRQGEMETYPLAGTAKRGVDVAEDRKLARALLNDAKEIAEHNM
LVDLHRNDIGRVAQFGTVKVRNLMDIKRFSHVQHISSEIVGILHPDEDMFSALASNFPAGTLSGAPKVEAIKVINELEPD
GRGAYGGALGSFNFNGDCIFAIPIRSLFINGESAYAQTCGGNVYDSNPADEYLEIQRKLSAMKVVLDSFMNP

Sequences:

>Translated_472_residues
MTSPTLQYDQPATIDIPSKPQRIKLTQDIDFFALFKRIERVFDTCYLLESLGEDSHMSRHHAIGFDPVMTIAAIDRTTLA
ITDNKTAETKHYQTDNPYQLLRTITPQHVIAREQSGGLVGYLGYDCVNFFEPSLNAKPSDDFEPFKFGVYLDGLTLDKMT
GEIFYFYYPTAQQDNRIEQIKALLDVPIPSYKPPTVEFLGDGMSQEEHAKVVMQVKEDIISGRIFQCEVGFKSKYRIAGD
KMPIYEKLRAVNPSPHMYFMKFAQQCIIGASPELLFRLRQGEMETYPLAGTAKRGVDVAEDRKLARALLNDAKEIAEHNM
LVDLHRNDIGRVAQFGTVKVRNLMDIKRFSHVQHISSEIVGILHPDEDMFSALASNFPAGTLSGAPKVEAIKVINELEPD
GRGAYGGALGSFNFNGDCIFAIPIRSLFINGESAYAQTCGGNVYDSNPADEYLEIQRKLSAMKVVLDSFMNP
>Mature_471_residues
TSPTLQYDQPATIDIPSKPQRIKLTQDIDFFALFKRIERVFDTCYLLESLGEDSHMSRHHAIGFDPVMTIAAIDRTTLAI
TDNKTAETKHYQTDNPYQLLRTITPQHVIAREQSGGLVGYLGYDCVNFFEPSLNAKPSDDFEPFKFGVYLDGLTLDKMTG
EIFYFYYPTAQQDNRIEQIKALLDVPIPSYKPPTVEFLGDGMSQEEHAKVVMQVKEDIISGRIFQCEVGFKSKYRIAGDK
MPIYEKLRAVNPSPHMYFMKFAQQCIIGASPELLFRLRQGEMETYPLAGTAKRGVDVAEDRKLARALLNDAKEIAEHNML
VDLHRNDIGRVAQFGTVKVRNLMDIKRFSHVQHISSEIVGILHPDEDMFSALASNFPAGTLSGAPKVEAIKVINELEPDG
RGAYGGALGSFNFNGDCIFAIPIRSLFINGESAYAQTCGGNVYDSNPADEYLEIQRKLSAMKVVLDSFMNP

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=421, Percent_Identity=31.8289786223278, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1787518, Length=364, Percent_Identity=33.7912087912088, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786809, Length=226, Percent_Identity=27.8761061946903, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082077, Length=220, Percent_Identity=27.7272727272727, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=442, Percent_Identity=33.9366515837104, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324361, Length=381, Percent_Identity=22.0472440944882, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 52971; Mature: 52840

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTLQYDQPATIDIPSKPQRIKLTQDIDFFALFKRIERVFDTCYLLESLGEDSHMSRH
CCCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHH
HAIGFDPVMTIAAIDRTTLAITDNKTAETKHYQTDNPYQLLRTITPQHVIAREQSGGLVG
CCCCCCHHHHHEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHEECCCCCEEE
YLGYDCVNFFEPSLNAKPSDDFEPFKFGVYLDGLTLDKMTGEIFYFYYPTAQQDNRIEQI
EHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEEEECCCCCCCCHHHHH
KALLDVPIPSYKPPTVEFLGDGMSQEEHAKVVMQVKEDIISGRIFQCEVGFKSKYRIAGD
HHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECCC
KMPIYEKLRAVNPSPHMYFMKFAQQCIIGASPELLFRLRQGEMETYPLAGTAKRGVDVAE
CCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCHHH
DRKLARALLNDAKEIAEHNMLVDLHRNDIGRVAQFGTVKVRNLMDIKRFSHVQHISSEIV
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHE
GILHPDEDMFSALASNFPAGTLSGAPKVEAIKVINELEPDGRGAYGGALGSFNFNGDCIF
EEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
AIPIRSLFINGESAYAQTCGGNVYDSNPADEYLEIQRKLSAMKVVLDSFMNP
EEEEEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPTLQYDQPATIDIPSKPQRIKLTQDIDFFALFKRIERVFDTCYLLESLGEDSHMSRH
CCCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHH
HAIGFDPVMTIAAIDRTTLAITDNKTAETKHYQTDNPYQLLRTITPQHVIAREQSGGLVG
CCCCCCHHHHHEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHEECCCCCEEE
YLGYDCVNFFEPSLNAKPSDDFEPFKFGVYLDGLTLDKMTGEIFYFYYPTAQQDNRIEQI
EHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCEEEEECCCCCCCCHHHHH
KALLDVPIPSYKPPTVEFLGDGMSQEEHAKVVMQVKEDIISGRIFQCEVGFKSKYRIAGD
HHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECCC
KMPIYEKLRAVNPSPHMYFMKFAQQCIIGASPELLFRLRQGEMETYPLAGTAKRGVDVAE
CCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCHHH
DRKLARALLNDAKEIAEHNMLVDLHRNDIGRVAQFGTVKVRNLMDIKRFSHVQHISSEIV
HHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHE
GILHPDEDMFSALASNFPAGTLSGAPKVEAIKVINELEPDGRGAYGGALGSFNFNGDCIF
EEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
AIPIRSLFINGESAYAQTCGGNVYDSNPADEYLEIQRKLSAMKVVLDSFMNP
EEEEEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2703466 [H]